CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anemia D000740 21 associated lipids
Arteriosclerosis D001161 86 associated lipids
Asthma D001249 52 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Chancroid D002602 4 associated lipids
Chondrosarcoma D002813 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Erythroblastosis, Fetal D004899 2 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Eye Diseases D005128 12 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Galactosemias D005693 5 associated lipids
Glioma D005910 112 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hypertension D006973 115 associated lipids
Hypoglycemia D007003 13 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Insulinoma D007340 28 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 100 | Total 79

PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

Download all related citations
Per page 10 20 50 100 | Total 4982
Authors Title Published Journal PubMed Link
Maher F and Simpson IA The GLUT3 glucose transporter is the predominant isoform in primary cultured neurons: assessment by biosynthetic and photoaffinity labelling. 1994 Biochem. J. pmid:8042980
Miyamoto K et al. Characterization of the rabbit intestinal fructose transporter (GLUT5). 1994 Biochem. J. pmid:7980458
Rubin RP et al. Activation of (arachidonyl) phosphatidylinositol turnover in rabbit neutrophils by the calcium ionophore A23187. 1981 Biochem. J. pmid:6796062
Good AH et al. Characterization of monoclonal antibodies that recognize band 4.5 polypeptides associated with nucleoside transport in pig erythrocytes. 1987 Biochem. J. pmid:3446189
Sorbara LR et al. Thrombin-induced translocation of GLUT3 glucose transporters in human platelets. 1997 Biochem. J. pmid:9371709
Edwards SW et al. Oxygen-radical production during inflammation may be limited by oxygen concentration. 1984 Biochem. J. pmid:6712601
Yano Y and May JM Ligand-induced conformational changes modify proteolytic cleavage of the adipocyte insulin-sensitive glucose transporter. 1993 Biochem. J. pmid:8216214
Martin GE et al. Kinetics and thermodynamics of the binding of forskolin to the galactose-H+ transport protein, GalP, of Escherichia coli. 1995 Biochem. J. pmid:7755573
McDonald TP and Henderson PJ Cysteine residues in the D-galactose-H+ symport protein of Escherichia coli: effects of mutagenesis on transport, reaction with N-ethylmaleimide and antibiotic binding. 2001 Biochem. J. pmid:11171069
Mesmer OT et al. Use of a genetic variant to study the hexose transport properties of human skin fibroblasts. 1990 Biochem. J. pmid:2306216
Sofue M et al. ADP modifies the function of the glucose transporter: studies with reconstituted liposomes. 1993 Biochem. J. pmid:8318016
Threadgold LC et al. Monosaccharide transport into lactating-rat mammary acini. 1982 Biochem. J. pmid:6214256
Sofue M et al. Possible multifunction of glucose transporter. Transport of nicotinamide by reconstituted liposomes. 1992 Biochem. J. pmid:1463467
Segal J The effect of trypsin on sugar uptake in rat thymocytes. Modulation of cellular cyclic AMP concentration and the sugar-transport system. 1987 Biochem. J. pmid:2825642
Azhar S and Menon KM Receptor-mediated gonadotropin action in the ovary. Action of cytoskeletal element-disrupting agents on gonadotropin-induced steroidogenesis in rat luteal cells. 1981 Biochem. J. pmid:6272724
Nishimura H et al. Monoclonal antibodies possibly recognize conformational changes in the human erythrocyte glucose transporter. 1992 Biochem. J. pmid:1731746
Vissers MC and Winterbourn CC Activation of human neutrophil gelatinase by endogenous serine proteinases. 1988 Biochem. J. pmid:2829854
Hallett MB and Campbell AK Uptake of liposomes containing the photoprotein obelin by rat isolated adipocytes. Adhesion, endocytosis or fusion? 1980 Biochem. J. pmid:7236227
Amrolia P et al. An investigation of glucose uptake in relation to steroidogenesis in rat testis and tumour Leydig cells. 1988 Biochem. J. pmid:2833234
Pinches SA et al. Preparation and characterization of basolateral membrane vesicles from pig and human colonocytes: the mechanism of glucose transport. 1993 Biochem. J. pmid:8396917
Stutchfield J and Cockcroft S Correlation between secretion and phospholipase D activation in differentiated HL60 cells. 1993 Biochem. J. pmid:8352731
Rathinavelu A and Isom GE Differential internalization and processing of atrial-natriuretic-factor B and C receptor in PC12 cells. 1991 Biochem. J. pmid:1646602
Afzal I et al. Interactions of ATP, oestradiol, genistein and the anti-oestrogens, faslodex (ICI 182780) and tamoxifen, with the human erythrocyte glucose transporter, GLUT1. 2002 Biochem. J. pmid:12133004
Moscat G et al. Ionophore A23187 induces a refractory state in thrombin-activated release of inositol phosphates. 1986 Biochem. J. pmid:3099773
Greco-Perotto R et al. Insulin modifies the properties of glucose transporters in rat brown adipose tissue. 1987 Biochem. J. pmid:3318814
Davies A et al. Site-specific antibodies as probes of the topology and function of the human erythrocyte glucose transporter. 1990 Biochem. J. pmid:1691633
Mesmer OT and Lo TC Hexose transport in human myoblasts. 1989 Biochem. J. pmid:2818559
Obermaier-Kusser B et al. Regulation of glucose carrier activity by AlCl3 and phospholipase C in fat-cells. 1988 Biochem. J. pmid:3066348
Joost HG et al. Qualitative and quantitative comparison of glucose transport activity and glucose transporter concentration in plasma membranes from basal and insulin-stimulated rat adipose cells. 1988 Biochem. J. pmid:3277616
Mühlbacher C et al. Phorbol esters imitate in rat fat-cells the full effect of insulin on glucose-carrier translocation, but not on 3-O-methylglucose-transport activity. 1988 Biochem. J. pmid:3281656
Zaninetti D et al. Effects of insulin on glucose transport and glucose transporters in rat heart. 1988 Biochem. J. pmid:3281662
Obermaier-Kusser B et al. Further evidence for a two-step model of glucose-transport regulation. Inositol phosphate-oligosaccharides regulate glucose-carrier activity. 1989 Biochem. J. pmid:2803236
Gélas P et al. Human neutrophil phospholipase D activation by N-formylmethionyl-leucylphenylalanine reveals a two-step process for the control of phosphatidylcholine breakdown and oxidative burst. 1992 Biochem. J. pmid:1417792
Hallett MB and Campbell AK Two distinct mechanisms for stimulation of oxygen-radical production by polymorphonuclear leucocytes. 1983 Biochem. J. pmid:6318738
Halperin ML and Cheema-Dhadli S Comparison of glucose and fructose transport into adipocytes of the rat. 1982 Biochem. J. pmid:7046737
Van der Wijk T et al. Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels. 1999 Biochem. J. pmid:10527936
Cherqui G et al. Evidence for surface glycoprotein involvement in the intracellular bioactivity of insulin in rat adipocytes. 1983 Biochem. J. pmid:6351847
Ryder JW et al. In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle. 1999 Biochem. J. pmid:10455018
Rist RJ and Naftalin RJ Dexamethasone inhibits the hexose monophosphate shunt in activated rat peritoneal macrophages by reducing hexokinase-dependent sugar uptake. 1991 Biochem. J. pmid:1883324
Zierath JR et al. Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle. 1995 Biochem. J. pmid:7487889
Roberts PA et al. Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes. 1985 Biochem. J. pmid:4004786
vom Dahl S et al. Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures. 1995 Biochem. J. pmid:7772037
Chen SR and Lo TC Cytochalasin B as a probe for the two hexose-transport systems in rat L6 myoblasts. 1988 Biochem. J. pmid:3390161
Inukai K et al. Replacement of both tryptophan residues at 388 and 412 completely abolished cytochalasin B photolabelling of the GLUT1 glucose transporter. 1994 Biochem. J. pmid:8092986
Goebeler M et al. Increase of calcium levels in epithelial cells induces translocation of calcium-binding proteins migration inhibitory factor-related protein 8 (MRP8) and MRP14 to keratin intermediate filaments. 1995 Biochem. J. pmid:7542868
Lakshmanan J Involvement of cytoskeletal structures in nerve-growth-factor-mediated induction of ornithine decarboxylase. 1979 Biochem. J. pmid:571277
Tu YP et al. Cytoplasmic Ca2+ inhibits the glucose transporter of human erythrocytes. 1995 Biochem. Mol. Biol. Int. pmid:7663442
Bennett BL et al. Glucose transport in a murine mammary epithelial cell line. 1997 Biochem. Mol. Biol. Int. pmid:9238530
Brooks SP and Storey KB Glycolytic enzyme binding in Otala lactea hepatopancreas: effect of taxol, colchicine and cytochalasin B and D on the in vivo enzyme distribution. 1997 Biochem. Mol. Biol. Int. pmid:9111945
Michelakakis H and Danpure CJ The effect of cytochalasin B on the release of lysosomal enzymes and intra-lysosomally-stored polyvinylpyrrolidone in the isolated perfused rat liver. 1984 Biochem. Pharmacol. pmid:6430298
Elferink JG Chlorpromazine inhibits phagocytosis and exocytosis in rabbit polymorphonuclear leukocytes. 1979 Biochem. Pharmacol. pmid:375938
Tsuruo T and Iida H Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. 1986 Biochem. Pharmacol. pmid:3457567
Skidgel RA et al. Metabolism of substance P and bradykinin by human neutrophils. 1991 Biochem. Pharmacol. pmid:1708255
Smith RJ and Iden SS Pharmacological modulation of chemotactic factor-elicited release of granule-associated enzymes from human neutrophils. Effects of prostaglandins, nonsteroid anti-inflammatory agents and corticosteroids. 1980 Biochem. Pharmacol. pmid:7426044
Theodoropoulos PA et al. Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping. 1994 Biochem. Pharmacol. pmid:8204105
Smith RJ et al. Stimulation of the human neutrophil superoxide anion-generating system with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine. 1984 Biochem. Pharmacol. pmid:6324816
Dayer JM et al. Effects of prostaglandin E2, indomethacin, trifluoperazine and drugs affecting the cytoskeleton on collagenase production by cultured adherent rheumatoid synovial cells. 1984 Biochem. Pharmacol. pmid:6089839
Zhou HL et al. Association between leukotriene B4-induced phospholipase D activation and degranulation of human neutrophils. 1993 Biochem. Pharmacol. pmid:8394074
Fujita H et al. Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B. 2005 Biochem. Pharmacol. pmid:15869745
Michelakakis H and Danpure CJ The release of intralysosomally-stored 125I-Triton WR-1339 and lysosomal enzymes from the isolated perfused rat liver in the presence and absence of cytochalasin B. 1986 Biochem. Pharmacol. pmid:3082335
Soares-da-Silva P Actin cytoskeleton, tubular sodium and the renal synthesis of dopamine. 1992 Biochem. Pharmacol. pmid:1449540
DoKhac L et al. Differential role of microtubules in the control of prostaglandin E2 and beta-adrenergic stimulation of cyclic AMP accumulation in the rat myometrium. 1983 Biochem. Pharmacol. pmid:6193795
Trush MA et al. Oxidant-mediated electronic excitation of imipramine. 1984 Biochem. Pharmacol. pmid:6329228
Lucas M and Solano F Opposite effect of cytochalasin B on agonist-induced respiratory burst in neutrophils and monocytes. 1991 Biochem. Pharmacol. pmid:1859454
Kim JY et al. Src-mediated regulation of inflammatory responses by actin polymerization. 2010 Biochem. Pharmacol. pmid:19769947
Malaisse WJ et al. The coupling of metabolic to secretory events in pancreatic islets: inhibition by 2-cyclohexene-1-one of the secretory response to cyclic AMP and cytochalasin B. 1986 Biochem. Pharmacol. pmid:2877668
Smith RJ et al. Human neutrophil activation with interleukin-1. A role for intracellular calcium and arachidonic acid lipoxygenation. 1987 Biochem. Pharmacol. pmid:2825706
Smith RJ Phagocytic release of lysosomal enzymes from guinea pig neutrophils--regulation by corticosteroids, autonomic neurohormones and cyclic nucleotides. 1977 Biochem. Pharmacol. pmid:21664
Stournaras C et al. Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B. 1996 Biochem. Pharmacol. pmid:8937443
Morita K et al. Effects of cytoskeleton-disrupting drugs on ouabain-stimulated catecholamine secretion from cultured adrenal chromaffin cells. 1988 Biochem. Pharmacol. pmid:3401261
Michelakakis H and Danpure CJ The effect of cytochalasin B on the release of lysosomal enzymes from isolated rat hepatocytes [proceedings]. 1979 Biochem. Soc. Trans. pmid:119657
Walmsley AR et al. The pre-steady-state kinetics of conformational changes in sugar transporters. 1994 Biochem. Soc. Trans. pmid:7821656
al-Habori M et al. Cytochalasins potently inhibit glycogen synthesis in hepatocyte cultures by an indirect mechanism. 1991 Biochem. Soc. Trans. pmid:1794472
Michelakakis H and Danpure CJ The uptake and release of lysosomal enzymes by isolated perfused rat liver. 1980 Biochem. Soc. Trans. pmid:6778741
Drewes LR et al. Inhibition of unidirectional influx of glucose into the isolated perfused dog brain by cytochalasin B. 1976 Biochem. Soc. Trans. pmid:1001606
Schmitt M and Bültmann B Fluorescent chemotactic peptides as tools to identify the f-Met-Leu-Phe receptor on human granulocytes. 1990 Biochem. Soc. Trans. pmid:2379691
Brant AM et al. Immunological identification of five members of the human facilitative glucose transporter family. 1992 Biochem. Soc. Trans. pmid:1426534
O'Dowd Y and Newsholme P Regulation of superoxide production in human polymorphonuclear leukocytes (PMNs). 1997 Biochem. Soc. Trans. pmid:9191411
Charalambous BM et al. Detection of proton-linked sugar transport proteins in Enterobacteriaceae. 1989 Biochem. Soc. Trans. pmid:2546838
Hales CN et al. Sugar transport in lysosomes? 1982 Biochem. Soc. Trans. pmid:7199491
Jones MN and Nickson JK The human erythrocyte monosaccharide transporter in bilayer lipid membranes. 1982 Biochem. Soc. Trans. pmid:7199492
Haslam RJ and Lynham JA Increased phosphorylation of specific blood platelet proteins in association with the release reaction. 1976 Biochem. Soc. Trans. pmid:187490
Dean RT Effects of cytochalasin B on the pinocytosis and degradation of proteins by macrophages [proceedings]. 1979 Biochem. Soc. Trans. pmid:570939
Gallo SA et al. HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process. 2001 Biochemistry pmid:11591141
Tsukamoto T et al. Adenosine cyclic 3',5'-monophosphate uptake and regulation of membrane protein kinase in intact human erythrocytes. 1980 Biochemistry pmid:6243958
Carruthers A and Melchior DL Human erythrocyte hexose transporter activity is governed by bilayer lipid composition in reconstituted vesicles. 1984 Biochemistry pmid:6543323
Schürmann A et al. Role of conserved arginine and glutamate residues on the cytosolic surface of glucose transporters for transporter function. 1997 Biochemistry pmid:9335548
May JM et al. Tryptic digestion of the human erythrocyte glucose transporter: effects on ligand binding and tryptophan fluorescence. 1993 Biochemistry pmid:8373759
Burant CF and Bell GI Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. 1992 Biochemistry pmid:1420159
King AP et al. Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding. 1991 Biochemistry pmid:1747373
May JM and Beechem JM Monitoring conformational change in the human erythrocyte glucose carrier: use of a fluorescent probe attached to an exofacial carrier sulfhydryl. 1993 Biochemistry pmid:8457556
Hebert DN and Carruthers A Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers. 1991 Biochemistry pmid:2029513
Gorga FR and Lienhard GE Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. 1981 Biochemistry pmid:7295669
Cloherty EK et al. Regulation of GLUT1-mediated sugar transport by an antiport/uniport switch mechanism. 1996 Biochemistry pmid:8855962
Axelrod JD and Pilch PF Unique cytochalasin B binding characteristics of the hepatic glucose carrier. 1983 Biochemistry pmid:6683102
Shanahan MF Characterization of cytochalasin B photoincorporation into human erythrocyte D-glucose transporter and F-actin. 1983 Biochemistry pmid:6683567
Reyes AM et al. Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. 2002 Biochemistry pmid:12069599
Robichaud T et al. Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site. 2011 Biochemistry pmid:21384913
Lienhard GE et al. Monosaccharide transport system of the human erythrocyte. Identification of the cytochalasin B binding component. 1977 Biochemistry pmid:911802
Sultzman LA and Carruthers A Stop-flow analysis of cooperative interactions between GLUT1 sugar import and export sites. 1999 Biochemistry pmid:10350483