CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Glucose Intolerance D018149 13 associated lipids
CREST Syndrome D017675 2 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Wounds and Injuries D014947 20 associated lipids
Wiskott-Aldrich Syndrome D014923 3 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Uremia D014511 33 associated lipids
Tuberculosis D014376 20 associated lipids
Trisomy D014314 6 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Starvation D013217 47 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Aggressive Periodontitis D010520 8 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Neutropenia D009503 15 associated lipids
Melanoma D008545 69 associated lipids
Medulloblastoma D008527 22 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Lymphoma D008223 18 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia D007938 74 associated lipids
Kidney Diseases D007674 29 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Insulinoma D007340 28 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Hypoglycemia D007003 13 associated lipids
Hypertension D006973 115 associated lipids
Hyperinsulinism D006946 27 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Per page 10 20 50 100 | Total 79

PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

Download all related citations
Per page 10 20 50 100 | Total 4982
Authors Title Published Journal PubMed Link
Nejmeddine M et al. HTLV-1-Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse. 2009 Blood pmid:19494354
Hooser SB et al. Actin filament alterations in rat hepatocytes induced in vivo and in vitro by microcystin-LR, a hepatotoxin from the blue-green alga, Microcystis aeruginosa. 1991 Vet. Pathol. pmid:1949504
Stirling P and Richmond S The developmental cycle of Chlamydia trachomatis in McCoy cells treated with cytochalasin B. 1977 J. Gen. Microbiol. pmid:195005
Huang AX et al. Nitric oxide, actin reorganization and vacuoles change are involved in PEG 6000-induced stomatal closure in Vicia faba. 2009 Physiol Plant pmid:19508367
Fenwick M and Roizman B Regulation of herpesvirus macromolecular synthesis. VI. Synthesis and modification of viral polypeptides in enucleated cells. 1977 J. Virol. pmid:195087
Iyengar R et al. Involvement of microtubules and microfilaments in the action of vasopressing in canine renal medulla. 1976 J. Supramol. Struct. pmid:195139
Pickart L and Thaler MM Pyruvate-induced changes in hepatoma cell morphology and macromolecular synthesis. 1976 J. Supramol. Struct. pmid:195140
Goodyear LJ et al. Glucose transporter number, activity, and isoform content in plasma membranes of red and white skeletal muscle. 1991 Am. J. Physiol. pmid:1951679
Root-Bernstein R and Vonck J Glucose binds to the insulin receptor affecting the mutual affinity of insulin and its receptor. 2009 Cell. Mol. Life Sci. pmid:19554259
Morisset J and Beaudoin AR Biochemical reactions involved in pancreatic enzyme secretion. 4. Effects of cytochalasin B on functions of the exocrine pancreas. 1977 Can. J. Physiol. Pharmacol. pmid:195693
Storrie B and Edelson PJ Distribution of concanavalin A in fibroblasts: direct endocytosis versus surface capping. 1977 Cell pmid:195744
Huang YC et al. Anti-inflammatory flavonoids from the rhizomes of Helminthostachys zeylanica. 2009 J. Nat. Prod. pmid:19583252
Mittelman L et al. Fast cell membrane displacements in B lymphocytes. Modulation by dihydrocytochalasin B and colchicine. 1991 FEBS Lett. pmid:1959663
Gantenberg HW et al. Micronuclei in human lymphocytes irradiated in vitro or in vivo. 1991 Radiat. Res. pmid:1961924
Shibamoto Y et al. Tumor radiosensitivity prediction by the cytokinesis-block micronucleus assay. 1991 Radiat. Res. pmid:1961926
Gusakova SV et al. [Research of cytoskeleton-dependent mechanisms of contractile activity regulation in the smooth muscles]. 2009 Ross Fiziol Zh Im I M Sechenova pmid:19639882
Nowak D et al. Chemotactic activity of histones for human polymorphonuclear leukocytes. 1990 Exp Pathol pmid:1964132
Morita K et al. Enhancement by cytochalasin B of ouabain-stimulated catecholamine secretion from cultured bovine adrenal chromaffin cells: possible relation to alteration in Na+/K(+)-pump activity. 1990 Cell. Mol. Neurobiol. pmid:1965424
Chang LY et al. Inhibitory effects of safrole on phagocytosis, intracellular reactive oxygen species, and the activity of myeloperoxidase released by human polymorphonuclear leukocytes. 2009 J. Periodontol. pmid:19656034
Wenzel-Seifert K and Seifert R Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells. 1990 Immunobiology pmid:1966023
Mrotek JJ and Hall PF Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B. 1977 Biochemistry pmid:196628
Deng YL et al. The role of actin in changes of cell shape and steroidogenesis in mouse Y-1 cells stimulated by ACTH--immunocytochemical studies. 1990 Tokai J. Exp. Clin. Med. pmid:1966696
Rodríguez-Enríquez S et al. Kinetics of transport and phosphorylation of glucose in cancer cells. 2009 J. Cell. Physiol. pmid:19681047
Egli D et al. Reprogramming after chromosome transfer into mouse blastomeres. 2009 Curr. Biol. pmid:19682906
Scott J et al. Dual action of phenylarsine oxide on the glucose transport activity of GLUT1. 2009 Chem. Biol. Interact. pmid:19686715
Poeckel D et al. Interference of alpha-alkyl-substituted pirinixic acid derivatives with neutrophil functions and signalling pathways. 2009 Eur. J. Pharmacol. pmid:19686721
Cunnick JM et al. Bcr and Abr cooperate in negatively regulating acute inflammatory responses. 2009 Mol. Cell. Biol. pmid:19703997
Kimelberg HK et al. Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. 1990 J. Neurosci. pmid:1970603
Pandey AK and Sodhi A Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway. 2009 Int. Immunol. pmid:19736292
Nath CJ and Ong T Micronuclei assay in cytokinesis-blocked binucleated and conventional mononucleated methods in human peripheral lymphocytes. 1990 Teratog., Carcinog. Mutagen. pmid:1975131
Kim JY et al. Src-mediated regulation of inflammatory responses by actin polymerization. 2010 Biochem. Pharmacol. pmid:19769947
Boriskin IuS [Cytochalasins in virologic research]. 1977 Mar-Apr Vopr. Virusol. pmid:197711
Kurosawa M et al. Inhibitory effects of azelastine on superoxide anion generation from activated inflammatory cells measured by a simple chemiluminescence method. 1990 Arzneimittelforschung pmid:1977394
Geppert TD and Lipsky PE Regulatory role of microfilaments in the induction of T4 cell proliferation and interleukin 2 production. 1990 Cell. Immunol. pmid:1977524
Beebe LF et al. Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos. 2009 Cloning Stem Cells pmid:19780698
Sudarikova AV et al. [Functional properties of sodium channels in cholesterol-depleted K562 cells]. 2009 Tsitologiia pmid:19799352
Ouahbi A et al. Comparative studies of volume restoration following cold-stress induced swelling in renal tissues--I. Effects of ouabain, K+ free medium, colchicine and cytochalasin B on rat and rabbit kidney cortex slices. 1990 Comp Biochem Physiol A Comp Physiol pmid:1982939
Norgauer J et al. Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils. 1991 J. Immunol. pmid:1988505
Hoki S et al. Enhancement of fibrinolysis by gel-filtered platelets and its quenching by cytochalasin B and GPIIb/IIIa antagonists. 2009 Sep-Oct Pharmacol Rep pmid:19904011
Kolber MA Enhancement of redirected target cell lysis by cytotoxic T lymphocytes in the presence of cytochalasin B. 1991 Cell. Immunol. pmid:1991331
Gu S et al. Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo. 2009 Mol. Cancer pmid:19948074
Mazur MT and Williamson JR Macrophage deformability and phagocytosis. 1977 J. Cell Biol. pmid:199608
Root RK and Metcalf JA H2O2 release from human granulocytes during phagocytosis. Relationship to superoxide anion formation and cellular catabolism of H2O2: studies with normal and cytochalasin B-treated cells. 1977 J. Clin. Invest. pmid:199619
Ebisuzaki K et al. Temporal mapping of the differentiation pathway of the murine erythroleukemia cell. 1991 Cancer Res. pmid:1998957
Wang C et al. Analysis of cat oocyte activation methods for the generation of feline disease models by nuclear transfer. 2009 Reprod. Biol. Endocrinol. pmid:20003339
Mooradian AD and Morin AM Brain uptake of glucose in diabetes mellitus: the role of glucose transporters. 1991 Am. J. Med. Sci. pmid:2000888
Murray D et al. Effect of thiols on micronucleus frequency in gamma-irradiated mammalian cells. 1991 Mutat. Res. pmid:2002801
Youn JH et al. Calcium stimulates glucose transport in skeletal muscle by a pathway independent of contraction. 1991 Am. J. Physiol. pmid:2003578
Harik SI et al. Chronic hyperglycemia increases the density of glucose transporters in human erythrocyte membranes. 1991 J. Clin. Endocrinol. Metab. pmid:2005206
Cai X et al. Connection between biomechanics and cytoskeleton structure of lymphocyte and Jurkat cells: An AFM study. 2010 Micron pmid:20060729
Vedeler A et al. The characterization of free, cytoskeletal and membrane-bound polysomes in Krebs II ascites and 3T3 cells. 1991 Mol. Cell. Biochem. pmid:2008179
Noonan KD et al. The role of plasma membrane and intracellular microskeletal elements in determining the lectin agglutinability of two CHO sub-clones. 1977 Prog. Clin. Biol. Res. pmid:200961
Al-Zubairi AS et al. Evaluation of the genotoxicity of zerumbone in cultured human peripheral blood lymphocytes. 2010 Toxicol In Vitro pmid:20123012
Ohkuro M and Hishinuma I The alpha integrin cytoplasmic motif KXGFFKR is essential for integrin-mediated leukocyte adhesion. 2010 Int. J. Mol. Med. pmid:20127050
Johnsson AK and Karlsson R Microtubule-dependent localization of profilin I mRNA to actin polymerization sites in serum-stimulated cells. 2010 Eur. J. Cell Biol. pmid:20129697
Milosević-Djordjević O et al. High micronucleus frequency in peripheral blood lymphocytes of untreated cancer patients irrespective of gender, smoking and cancer sites. 2010 Tohoku J. Exp. Med. pmid:20139662
Kirkland D Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit): summary of results in the collaborative trial. 2010 Mutat. Res. pmid:20149894
Schettler A et al. Release of proteinases from stimulated polymorphonuclear leukocytes. Evidence for subclasses of the main granule types and their association with cytoskeletal components. 1991 Eur. J. Biochem. pmid:2015820
Robinson JC and Kaufman PL Cytochalasin B potentiates epinephrine's outflow facility-increasing effect. 1991 Invest. Ophthalmol. Vis. Sci. pmid:2016142
Suzuki N and Mihashi K Binding mode of cytochalasin B to F-actin is altered by lateral binding of regulatory proteins. 1991 J. Biochem. pmid:2016267
Bennett K and de Vellis J Reversible inhibition of the norepinephrine induction of lactate dehydrogenase by cytochalasin B in rat glial C6 cells. 1977 J. Cell. Physiol. pmid:201647
Lowes DA et al. Dehydroascorbic acid as pre-conditioner: protection from lipopolysaccharide induced mitochondrial damage. 2010 Free Radic. Res. pmid:20166893
Kirkland D Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit): introduction to the collaborative trial. 2010 Mutat. Res. pmid:20176128
Carruthers A and Helgerson AL Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B. 1991 Biochemistry pmid:2018762
Ubels JL and Osgood TB Inhibition of corneal epithelial cell migration by cadmium and mercury. 1991 Bull Environ Contam Toxicol pmid:2018869
Katagiri H et al. Substitution of leucine for tryptophan 412 does not abolish cytochalasin B labeling but markedly decreases the intrinsic activity of GLUT1 glucose transporter. 1991 J. Biol. Chem. pmid:2019601
Fowler P et al. Cadmium chloride, benzo[a]pyrene and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Covance laboratories, Harrogate UK in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20206291
Fowler P et al. Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20226265
Brasen JC et al. On the mechanism of oscillations in neutrophils. 2010 Biophys. Chem. pmid:20227815
Cura AJ and Carruthers A Acute modulation of sugar transport in brain capillary endothelial cell cultures during activation of the metabolic stress pathway. 2010 J. Biol. Chem. pmid:20231288
Ishihara H et al. The glucose transport activity of GLUT1 is markedly decreased by substitution of a single amino acid with a different charge at residue 415. 1991 Biochem. Biophys. Res. Commun. pmid:2025301
May JM The one-site model of human erythrocyte glucose transport: testing its predictions using network thermodynamic computer simulations. 1991 Biochim. Biophys. Acta pmid:2025630
Stitt AW et al. Fasciola hepatica: disruption of spermatogenesis by the microfilament inhibitor cytochalasin B. 1991 Parasitol. Res. pmid:2027880
Hebert DN and Carruthers A Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers. 1991 Biochemistry pmid:2029513
Khalbuss WE and Wondergem R Involvement of cell calcium and transmembrane potential in control of hepatocyte volume. 1991 Hepatology pmid:2030001
Mattila JT et al. Phagocytosis of the Lyme disease spirochete, Borrelia burgdorferi, by cells from the ticks, Ixodes scapularis and Dermacentor andersoni, infected with an endosymbiont, Rickettsia peacockii. 2007 J. Insect Sci. pmid:20331397
Becich MJ et al. Internalization of bacille Calmette-Guerin by bladder tumor cells. 1991 J. Urol. pmid:2033723
Elhajouji A Mitomycin C, 5-fluoruracil, colchicine and etoposide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Novartis in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20338262
Yamada C et al. Vitrification with glutamine improves maturation rate of vitrified / warmed immature bovine oocytes. 2011 Reprod. Domest. Anim. pmid:20345596
Nesslany F and Marzin D Cytosine arabinoside, vinblastine, diethylstilboestrol and 2-aminoanthracene tested in the in vitro human TK6 cell line micronucleus test (MNvit) at Institut Pasteur de Lille in support of OECD draft test guideline 487. 2010 Mutat. Res. pmid:20348020
Wang ZY et al. Actin microfilament involved in regulation of pacemaking activity in cultured interstitial cells of Cajal from murine intestine. 2010 J. Membr. Biol. pmid:20349180
Bogdanov AA et al. Restoration of adhesive potentials of Ehrlich ascites carcinoma cells by modification of plasma membrane. 1991 J. Cell. Physiol. pmid:2037621
Petrie L et al. Inhibition of myoblast differentiation by lack of zinc. 1991 Biochem. J. pmid:2039464
Schuler M et al. Evaluation of phenolphthalein, diazepam and quinacrine dihydrochloride in the in vitro mammalian cell micronucleus test in Chinese hamster ovary (CHO) and TK6 cells. 2010 Mutat. Res. pmid:20399283
Watanabe N et al. Motility of bile canaliculi in the living animal: implications for bile flow. 1991 J. Cell Biol. pmid:2040644
Gravett CM et al. Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. 2010 Eur. Respir. J. pmid:20413544
Whitwell J et al. 5-Fluorouracil, colchicine, benzo[a]pyrene and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster V79 cells at Covance Laboratories, Harrogate, UK in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20438860
Condeelis JS and Taylor DL The contractile basis of amoeboid movement. V. The control of gelation, solation, and contraction in extracts from Dictyostelium discoideum. 1977 J. Cell Biol. pmid:20447
Weiss RE and Wilbur KM Effects of cytochalasin B on division and calcium carbonate extrusion in a calcareous alga. 1978 Exp. Cell Res. pmid:204503
Cuello C et al. Superfine open pulled straws vitrification of porcine blastocysts does not require pretreatment with cytochalasin B and/or centrifugation. 2010 Reprod. Fertil. Dev. pmid:20450833
Whitwell J et al. 2-Aminoanthracene, 5-fluorouracil, colchicine, benzo[a]pyrene, cadmium chloride and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster ovary (CHO) cells at Covance Laboratories, Harrogate UK in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20478394
Taylor RB et al. Redistribution and pinocytosis of lymphocyte surface immunoglobulin molecules induced by anti-immunoglobulin antibody. 1971 Nature New Biol. pmid:20480991
Lipowsky HH et al. In vivo mechanical properties of leukocytes during adhesion to venular endothelium. 1991 Biorheology pmid:2049532
May JM and Qu ZC Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C? 2010 Arch. Biochem. Biophys. pmid:20510668
Zor U et al. Implication of microtubules and microfilaments in the response of the ovarian adenylate cyclase-cyclic AMP system to gonadotropins and prostaglandin E2. 1978 Biochem. Biophys. Res. Commun. pmid:205222
Sturm EM et al. CD203c-based basophil activation test in allergy diagnosis: characteristics and differences to CD63 upregulation. 2010 Cytometry B Clin Cytom pmid:20533392
Thorn NA et al. Characteristics of ascorbic acid uptake by isolated ox neurohypophyseal nerve terminals and the influence of glucocorticoid and tri-iodothyronine on uptake. 1991 Acta Physiol. Scand. pmid:2053450
Itasaki N et al. Actin bundles on the right side in the caudal part of the heart tube play a role in dextro-looping in the embryonic chick heart. 1991 Anat. Embryol. pmid:2053708
Kamel M et al. Inhibition of elastase enzyme release from human polymorphonuclear leukocytes by N-acetyl-galactosamine and N-acetyl-glucosamine. 1991 Jan-Feb Clin. Exp. Rheumatol. pmid:2054963
Tomanin R et al. Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block method. 1991 Mutagenesis pmid:2056912