Chaetoglobosins

Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.

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Introduction

To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Chaetoglobosins

MeSH term MeSH ID Detail
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Chaetoglobosins

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Chaetoglobosins?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Chaetoglobosins?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

What genes are associated with Chaetoglobosins?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Chaetoglobosins

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Authors Title Published Journal PubMed Link
Jiang C et al. Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. 2017 World J. Microbiol. Biotechnol. pmid:28466302
Hu Y et al. A PKS gene, pks-1, is involved in chaetoglobosin biosynthesis, pigmentation and sporulation in Chaetomium globosum. 2012 Sci China Life Sci pmid:23233225
Xu GB et al. Electrospray ionization tandem mass spectrometry of chaetoglobosins. 2012 Rapid Commun. Mass Spectrom. pmid:22886807
Walsh JP et al. Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. 2019 Rapid Commun. Mass Spectrom. pmid:30325552
Griffin JF et al. Inhibition of glucose transport in human erythrocytes by cytochalasins: A model based on diffraction studies. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6954518
Dhillon B et al. Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25733908
Ashrafi S et al. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. 2017 PLoS ONE pmid:28700638
Hu Y et al. Gα-cAMP/PKA pathway positively regulates pigmentation, chaetoglobosin A biosynthesis and sexual development in Chaetomium globosum. 2018 PLoS ONE pmid:29652900
Zhang J et al. Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum. 2010 Planta Med. pmid:20486076
Wang Y et al. Bioactive metabolites from Chaetomium globosum L18, an endophytic fungus in the medicinal plant Curcuma wenyujin. 2012 Phytomedicine pmid:22112725
Sidorova TS and Matesic DF Protective effect of the natural product, chaetoglobosin K, on lindane- and dieldrin-induced changes in astroglia: identification of activated signaling pathways. 2008 Pharm. Res. pmid:18040759
Yang MH et al. Aureochaeglobosins A-C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum. 2018 Org. Lett. pmid:29771535
Rogers KD et al. Diplodiatoxin, chaetoglobosins, and diplonine associated with a field outbreak of Stenocarpella ear rot in Illinois. 2014 Mycotoxin Res pmid:24504633
McMullin DR et al. Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment. 2013 Mycotoxin Res pmid:23334724
Fogle MR et al. Growth and mycotoxin production by Chaetomium globosum. 2007 Mycopathologia pmid:17551849
Knudsen PB et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. 2014 Leukemia pmid:24280868
Jiang T et al. Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. 2016 J. Nat. Prod. pmid:27759375
Chen C et al. Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare. 2015 J. Nat. Prod. pmid:26068802
Jiao W et al. Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum. 2004 J. Nat. Prod. pmid:15497948
Ding G et al. Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019. 2006 J. Nat. Prod. pmid:16499339