MeSH term | MeSH ID | Detail |
---|---|---|
Cholangiocarcinoma | D018281 | 7 associated lipids |
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.
To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Chaetoglobosins
MeSH term | MeSH ID | Detail |
---|---|---|
Cholangiocarcinoma | D018281 | 7 associated lipids |
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:10209577 | ||||
pmid: | ||||
Maruta H et al. | Cytoskeletal tumor suppressors that block oncogenic RAS signaling. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10667202 |
Luo H et al. | Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α. | 2013 | Anticancer Drugs | pmid:23695013 |
Frisvad JC et al. | Penicillium discolor, a new species from cheese, nuts and vegetables. | 1997 | Antonie Van Leeuwenhoek | pmid:9298190 |
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Maruyama K et al. | Effects of chaetoglobosin J on the G-F transformation of actin. | 1986 | Biochim. Biophys. Acta | pmid:3778915 |
Trendowski M | Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. | 2014 | Biochim. Biophys. Acta | pmid:25286320 |
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Jiang C et al. | New production process of the antifungal chaetoglobosin A using cornstalks. | Braz. J. Microbiol. | pmid:28223029 | |
Fogle MR et al. | Heat stability of chaetoglobosins A and C. | 2008 | Can. J. Microbiol. | pmid:18449228 |
Matesic DF et al. | Inhibition of cytokinesis and akt phosphorylation by chaetoglobosin K in ras-transformed epithelial cells. | 2006 | Cancer Chemother. Pharmacol. | pmid:16254733 |
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Li B et al. | Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells. | 2015 | Cancer Lett. | pmid:25304379 |
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Zhao SS et al. | Chaetomium globosum CDW7, a potential biological control strain and its antifungal metabolites. | 2017 | FEMS Microbiol. Lett. | pmid:28011695 |
Zheng QC et al. | Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum. | 2014 | Fitoterapia | pmid:24418656 |
Zhu X et al. | Penochalasin K, a new unusual chaetoglobosin from the mangrove endophytic fungus Penicillium chrysogenum V11 and its effective semi-synthesis. | 2017 | Fitoterapia | pmid:28958956 |
Straus DC | The possible role of fungal contamination in sick building syndrome. | 2011 | Front Biosci (Elite Ed) | pmid:21196335 |
Fog Nielsen K | Mycotoxin production by indoor molds. | 2003 | Fungal Genet. Biol. | pmid:12781669 |
Hua C et al. | Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway. | 2013 | Immunobiology | pmid:22739238 |
Ali A et al. | Dual modulation of JNK and Akt signaling pathways by chaetoglobosin K in human lung carcinoma and ras-transformed epithelial cells. | 2013 | Invest New Drugs | pmid:23054210 |
Cutler HG et al. | Chaetoglobosin K: a new plant growth inhibitor and toxin from Diplodia macrospora. | 1980 Jan-Feb | J. Agric. Food Chem. | pmid:7358926 |
Andersen B et al. | Penicillium expansum: consistent production of patulin, chaetoglobosins, and other secondary metabolites in culture and their natural occurrence in fruit products. | 2004 | J. Agric. Food Chem. | pmid:15080656 |
Hu Y et al. | Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. | 2013 | J. Agric. Food Chem. | pmid:23214998 |
Li H et al. | Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities. | 2014 | J. Agric. Food Chem. | pmid:24708412 |
Ishiuchi K et al. | Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis. | 2013 | J. Am. Chem. Soc. | pmid:23611317 |
Kobayashi H et al. | A screening method for antimitotic and antifungal substances using conidia of Pyricularia oryzae, modification and application to tropical marine fungi. | 1996 | J. Antibiot. | pmid:8931720 |
Shinohara C et al. | Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B. | 2000 | J. Antibiot. | pmid:10819297 |
Kawahara T et al. | New chaetoglobosin derivatives, MBJ-0038, MBJ-0039 and MBJ-0040, isolated from the fungus Chaetomium sp. f24230. | 2013 | J. Antibiot. | pmid:23881215 |
van Haelst C and Rothstein TL | Cytochalasin stimulates phosphoinositide metabolism in murine B lymphocytes. | 1988 | J. Immunol. | pmid:2830337 |
Cui CM et al. | Cytoglobosins A-G, cytochalasans from a marine-derived endophytic fungus, Chaetomium globosum QEN-14. | 2010 | J. Nat. Prod. | pmid:20225834 |
Jiang T et al. | Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. | 2016 | J. Nat. Prod. | pmid:27759375 |
Chen C et al. | Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare. | 2015 | J. Nat. Prod. | pmid:26068802 |
Christian OE et al. | Using jasplakinolide to turn on pathways that enable the isolation of new chaetoglobosins from Phomospis asparagi. | 2005 | J. Nat. Prod. | pmid:16309305 |
Jiao W et al. | Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum. | 2004 | J. Nat. Prod. | pmid:15497948 |
Ding G et al. | Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019. | 2006 | J. Nat. Prod. | pmid:16499339 |
Knudsen PB et al. | Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. | 2014 | Leukemia | pmid:24280868 |
Fogle MR et al. | Growth and mycotoxin production by Chaetomium globosum. | 2007 | Mycopathologia | pmid:17551849 |
Rogers KD et al. | Diplodiatoxin, chaetoglobosins, and diplonine associated with a field outbreak of Stenocarpella ear rot in Illinois. | 2014 | Mycotoxin Res | pmid:24504633 |
McMullin DR et al. | Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment. | 2013 | Mycotoxin Res | pmid:23334724 |
Yang MH et al. | Aureochaeglobosins A-C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum. | 2018 | Org. Lett. | pmid:29771535 |
Sidorova TS and Matesic DF | Protective effect of the natural product, chaetoglobosin K, on lindane- and dieldrin-induced changes in astroglia: identification of activated signaling pathways. | 2008 | Pharm. Res. | pmid:18040759 |
Wang Y et al. | Bioactive metabolites from Chaetomium globosum L18, an endophytic fungus in the medicinal plant Curcuma wenyujin. | 2012 | Phytomedicine | pmid:22112725 |
Zhang J et al. | Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum. | 2010 | Planta Med. | pmid:20486076 |
Ashrafi S et al. | Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. | 2017 | PLoS ONE | pmid:28700638 |
Hu Y et al. | Gα-cAMP/PKA pathway positively regulates pigmentation, chaetoglobosin A biosynthesis and sexual development in Chaetomium globosum. | 2018 | PLoS ONE | pmid:29652900 |
Griffin JF et al. | Inhibition of glucose transport in human erythrocytes by cytochalasins: A model based on diffraction studies. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6954518 |
Dhillon B et al. | Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25733908 |
Xu GB et al. | Electrospray ionization tandem mass spectrometry of chaetoglobosins. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22886807 |
Walsh JP et al. | Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. | 2019 | Rapid Commun. Mass Spectrom. | pmid:30325552 |
Hu Y et al. | A PKS gene, pks-1, is involved in chaetoglobosin biosynthesis, pigmentation and sporulation in Chaetomium globosum. | 2012 | Sci China Life Sci | pmid:23233225 |
Jiang C et al. | Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. | 2017 | World J. Microbiol. Biotechnol. | pmid:28466302 |