MeSH term | MeSH ID | Detail |
---|---|---|
Cholangiocarcinoma | D018281 | 7 associated lipids |
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.
To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Chaetoglobosins
MeSH term | MeSH ID | Detail |
---|---|---|
Cholangiocarcinoma | D018281 | 7 associated lipids |
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:10209577 | ||||
pmid: | ||||
Maruta H et al. | Cytoskeletal tumor suppressors that block oncogenic RAS signaling. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10667202 |
Luo H et al. | Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α. | 2013 | Anticancer Drugs | pmid:23695013 |
Frisvad JC et al. | Penicillium discolor, a new species from cheese, nuts and vegetables. | 1997 | Antonie Van Leeuwenhoek | pmid:9298190 |
Thohinung S et al. | Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01. | 2010 | Arch. Pharm. Res. | pmid:20803114 |
Wieland T and Löw I | Concentration-dependent influence of various cytochalasins and chaetoglobosins on the phalloidin-induced polymerization of G-actin in 0.6 M potassium iodide. | 1980 | Biochemistry | pmid:6893272 |
Maruyama K et al. | Effects of chaetoglobosin J on the G-F transformation of actin. | 1986 | Biochim. Biophys. Acta | pmid:3778915 |
Trendowski M | Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. | 2014 | Biochim. Biophys. Acta | pmid:25286320 |
Dou H et al. | Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages. | 2011 | Biol. Pharm. Bull. | pmid:22130243 |
Qin JC et al. | Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19246197 |
Jiang C et al. | New production process of the antifungal chaetoglobosin A using cornstalks. | Braz. J. Microbiol. | pmid:28223029 | |
Fogle MR et al. | Heat stability of chaetoglobosins A and C. | 2008 | Can. J. Microbiol. | pmid:18449228 |
Matesic DF et al. | Inhibition of cytokinesis and akt phosphorylation by chaetoglobosin K in ras-transformed epithelial cells. | 2006 | Cancer Chemother. Pharmacol. | pmid:16254733 |
Tikoo A et al. | Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445. | 1999 Sep-Oct | Cancer J Sci Am | pmid:10526670 |
Li B et al. | Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells. | 2015 | Cancer Lett. | pmid:25304379 |
Matesic DF et al. | Prevention of organochlorine-induced inhibition of gap junctional communication by chaetoglobosin K in astrocytes. | 2001 | Cell Biol. Toxicol. | pmid:11787861 |
Ge HM et al. | Precursor-directed fungal generation of novel halogenated chaetoglobosins with more preferable immunosuppressive action. | 2011 | Chem. Commun. (Camb.) | pmid:21152613 |
Sekita S et al. | Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J. | 1982 | Chem. Pharm. Bull. | pmid:7116505 |
Boettger D et al. | Evolutionary imprint of catalytic domains in fungal PKS-NRPS hybrids. | 2012 | Chembiochem | pmid:23023987 |