Chaetoglobosins

Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.

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Introduction

To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Chaetoglobosins

MeSH term MeSH ID Detail
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Chaetoglobosins

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Chaetoglobosins?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Chaetoglobosins?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

What genes are associated with Chaetoglobosins?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Chaetoglobosins

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Authors Title Published Journal PubMed Link
pmid:10209577
pmid:
Maruta H et al. Cytoskeletal tumor suppressors that block oncogenic RAS signaling. 1999 Ann. N. Y. Acad. Sci. pmid:10667202
Luo H et al. Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α. 2013 Anticancer Drugs pmid:23695013
Frisvad JC et al. Penicillium discolor, a new species from cheese, nuts and vegetables. 1997 Antonie Van Leeuwenhoek pmid:9298190
Thohinung S et al. Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01. 2010 Arch. Pharm. Res. pmid:20803114
Wieland T and Löw I Concentration-dependent influence of various cytochalasins and chaetoglobosins on the phalloidin-induced polymerization of G-actin in 0.6 M potassium iodide. 1980 Biochemistry pmid:6893272
Maruyama K et al. Effects of chaetoglobosin J on the G-F transformation of actin. 1986 Biochim. Biophys. Acta pmid:3778915
Trendowski M Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. 2014 Biochim. Biophys. Acta pmid:25286320
Dou H et al. Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages. 2011 Biol. Pharm. Bull. pmid:22130243