MeSH term | MeSH ID | Detail |
---|---|---|
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
Cholangiocarcinoma | D018281 | 7 associated lipids |
Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.
To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Chaetoglobosins
MeSH term | MeSH ID | Detail |
---|---|---|
Leukemia, Lymphocytic, Chronic, B-Cell | D015451 | 25 associated lipids |
Cholangiocarcinoma | D018281 | 7 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Walsh JP et al. | Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. | 2019 | Rapid Commun. Mass Spectrom. | pmid:30325552 |
Yang MH et al. | Aureochaeglobosins A-C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum. | 2018 | Org. Lett. | pmid:29771535 |
Hu Y et al. | Gα-cAMP/PKA pathway positively regulates pigmentation, chaetoglobosin A biosynthesis and sexual development in Chaetomium globosum. | 2018 | PLoS ONE | pmid:29652900 |
Jiang C et al. | Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. | 2017 | World J. Microbiol. Biotechnol. | pmid:28466302 |
Zhao SS et al. | Chaetomium globosum CDW7, a potential biological control strain and its antifungal metabolites. | 2017 | FEMS Microbiol. Lett. | pmid:28011695 |
Ashrafi S et al. | Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. | 2017 | PLoS ONE | pmid:28700638 |
Zhu X et al. | Penochalasin K, a new unusual chaetoglobosin from the mangrove endophytic fungus Penicillium chrysogenum V11 and its effective semi-synthesis. | 2017 | Fitoterapia | pmid:28958956 |
Jiang T et al. | Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. | 2016 | J. Nat. Prod. | pmid:27759375 |
Chen C et al. | Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare. | 2015 | J. Nat. Prod. | pmid:26068802 |
Dhillon B et al. | Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25733908 |
Li B et al. | Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells. | 2015 | Cancer Lett. | pmid:25304379 |
Rogers KD et al. | Diplodiatoxin, chaetoglobosins, and diplonine associated with a field outbreak of Stenocarpella ear rot in Illinois. | 2014 | Mycotoxin Res | pmid:24504633 |
Zheng QC et al. | Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum. | 2014 | Fitoterapia | pmid:24418656 |
Trendowski M | Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. | 2014 | Biochim. Biophys. Acta | pmid:25286320 |
Li H et al. | Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities. | 2014 | J. Agric. Food Chem. | pmid:24708412 |
Knudsen PB et al. | Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. | 2014 | Leukemia | pmid:24280868 |
Hua C et al. | Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway. | 2013 | Immunobiology | pmid:22739238 |
Kawahara T et al. | New chaetoglobosin derivatives, MBJ-0038, MBJ-0039 and MBJ-0040, isolated from the fungus Chaetomium sp. f24230. | 2013 | J. Antibiot. | pmid:23881215 |
Ishiuchi K et al. | Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis. | 2013 | J. Am. Chem. Soc. | pmid:23611317 |
Luo H et al. | Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α. | 2013 | Anticancer Drugs | pmid:23695013 |
Hu Y et al. | Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. | 2013 | J. Agric. Food Chem. | pmid:23214998 |
McMullin DR et al. | Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment. | 2013 | Mycotoxin Res | pmid:23334724 |
Ali A et al. | Dual modulation of JNK and Akt signaling pathways by chaetoglobosin K in human lung carcinoma and ras-transformed epithelial cells. | 2013 | Invest New Drugs | pmid:23054210 |
Wang Y et al. | Bioactive metabolites from Chaetomium globosum L18, an endophytic fungus in the medicinal plant Curcuma wenyujin. | 2012 | Phytomedicine | pmid:22112725 |
Xue M et al. | Chaetoglobosin Vb from endophytic Chaetomium globosum: absolute configuration of chaetoglobosins. | 2012 | Chirality | pmid:22593034 |
Xu GB et al. | Electrospray ionization tandem mass spectrometry of chaetoglobosins. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22886807 |
Hu Y et al. | A PKS gene, pks-1, is involved in chaetoglobosin biosynthesis, pigmentation and sporulation in Chaetomium globosum. | 2012 | Sci China Life Sci | pmid:23233225 |
Boettger D et al. | Evolutionary imprint of catalytic domains in fungal PKS-NRPS hybrids. | 2012 | Chembiochem | pmid:23023987 |
Ge HM et al. | Precursor-directed fungal generation of novel halogenated chaetoglobosins with more preferable immunosuppressive action. | 2011 | Chem. Commun. (Camb.) | pmid:21152613 |
Straus DC | The possible role of fungal contamination in sick building syndrome. | 2011 | Front Biosci (Elite Ed) | pmid:21196335 |
Dou H et al. | Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages. | 2011 | Biol. Pharm. Bull. | pmid:22130243 |
Thohinung S et al. | Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01. | 2010 | Arch. Pharm. Res. | pmid:20803114 |
Cui CM et al. | Cytoglobosins A-G, cytochalasans from a marine-derived endophytic fungus, Chaetomium globosum QEN-14. | 2010 | J. Nat. Prod. | pmid:20225834 |
Zhang J et al. | Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum. | 2010 | Planta Med. | pmid:20486076 |
Qin JC et al. | Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19246197 |
Sidorova TS and Matesic DF | Protective effect of the natural product, chaetoglobosin K, on lindane- and dieldrin-induced changes in astroglia: identification of activated signaling pathways. | 2008 | Pharm. Res. | pmid:18040759 |
Fogle MR et al. | Heat stability of chaetoglobosins A and C. | 2008 | Can. J. Microbiol. | pmid:18449228 |
Fogle MR et al. | Growth and mycotoxin production by Chaetomium globosum. | 2007 | Mycopathologia | pmid:17551849 |
Matesic DF et al. | Inhibition of cytokinesis and akt phosphorylation by chaetoglobosin K in ras-transformed epithelial cells. | 2006 | Cancer Chemother. Pharmacol. | pmid:16254733 |
Ding G et al. | Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019. | 2006 | J. Nat. Prod. | pmid:16499339 |
Christian OE et al. | Using jasplakinolide to turn on pathways that enable the isolation of new chaetoglobosins from Phomospis asparagi. | 2005 | J. Nat. Prod. | pmid:16309305 |
Andersen B et al. | Penicillium expansum: consistent production of patulin, chaetoglobosins, and other secondary metabolites in culture and their natural occurrence in fruit products. | 2004 | J. Agric. Food Chem. | pmid:15080656 |
Jiao W et al. | Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum. | 2004 | J. Nat. Prod. | pmid:15497948 |
Fog Nielsen K | Mycotoxin production by indoor molds. | 2003 | Fungal Genet. Biol. | pmid:12781669 |
Matesic DF et al. | Prevention of organochlorine-induced inhibition of gap junctional communication by chaetoglobosin K in astrocytes. | 2001 | Cell Biol. Toxicol. | pmid:11787861 |
Shinohara C et al. | Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B. | 2000 | J. Antibiot. | pmid:10819297 |
Tikoo A et al. | Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445. | 1999 Sep-Oct | Cancer J Sci Am | pmid:10526670 |
Maruta H et al. | Cytoskeletal tumor suppressors that block oncogenic RAS signaling. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10667202 |
Frisvad JC et al. | Penicillium discolor, a new species from cheese, nuts and vegetables. | 1997 | Antonie Van Leeuwenhoek | pmid:9298190 |
Kobayashi H et al. | A screening method for antimitotic and antifungal substances using conidia of Pyricularia oryzae, modification and application to tropical marine fungi. | 1996 | J. Antibiot. | pmid:8931720 |
Feuilloley M et al. | Effect of cytochalasin-B on the metabolism of polyphosphoinositides in andrenocortical cells. | 1993 | Endocrinology | pmid:8404684 |
van Haelst C and Rothstein TL | Cytochalasin stimulates phosphoinositide metabolism in murine B lymphocytes. | 1988 | J. Immunol. | pmid:2830337 |
Maruyama K et al. | Effects of chaetoglobosin J on the G-F transformation of actin. | 1986 | Biochim. Biophys. Acta | pmid:3778915 |
Sekita S et al. | Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J. | 1982 | Chem. Pharm. Bull. | pmid:7116505 |
Griffin JF et al. | Inhibition of glucose transport in human erythrocytes by cytochalasins: A model based on diffraction studies. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6954518 |
Cutler HG et al. | Chaetoglobosin K: a new plant growth inhibitor and toxin from Diplodia macrospora. | 1980 Jan-Feb | J. Agric. Food Chem. | pmid:7358926 |
Wieland T and Löw I | Concentration-dependent influence of various cytochalasins and chaetoglobosins on the phalloidin-induced polymerization of G-actin in 0.6 M potassium iodide. | 1980 | Biochemistry | pmid:6893272 |
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Jiang C et al. | New production process of the antifungal chaetoglobosin A using cornstalks. | Braz. J. Microbiol. | pmid:28223029 |