Chaetoglobosins

Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.

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Introduction

To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Chaetoglobosins

MeSH term MeSH ID Detail
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Chaetoglobosins

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Chaetoglobosins?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Chaetoglobosins?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

What genes are associated with Chaetoglobosins?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Chaetoglobosins

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Authors Title Published Journal PubMed Link
Frisvad JC et al. Penicillium discolor, a new species from cheese, nuts and vegetables. 1997 Antonie Van Leeuwenhoek pmid:9298190
Kobayashi H et al. A screening method for antimitotic and antifungal substances using conidia of Pyricularia oryzae, modification and application to tropical marine fungi. 1996 J. Antibiot. pmid:8931720
Feuilloley M et al. Effect of cytochalasin-B on the metabolism of polyphosphoinositides in andrenocortical cells. 1993 Endocrinology pmid:8404684
Cutler HG et al. Chaetoglobosin K: a new plant growth inhibitor and toxin from Diplodia macrospora. 1980 Jan-Feb J. Agric. Food Chem. pmid:7358926
Sekita S et al. Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J. 1982 Chem. Pharm. Bull. pmid:7116505
Griffin JF et al. Inhibition of glucose transport in human erythrocytes by cytochalasins: A model based on diffraction studies. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6954518
Wieland T and Löw I Concentration-dependent influence of various cytochalasins and chaetoglobosins on the phalloidin-induced polymerization of G-actin in 0.6 M potassium iodide. 1980 Biochemistry pmid:6893272
Maruyama K et al. Effects of chaetoglobosin J on the G-F transformation of actin. 1986 Biochim. Biophys. Acta pmid:3778915
Walsh JP et al. Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. 2019 Rapid Commun. Mass Spectrom. pmid:30325552
Yang MH et al. Aureochaeglobosins A-C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum. 2018 Org. Lett. pmid:29771535
Hu Y et al. Gα-cAMP/PKA pathway positively regulates pigmentation, chaetoglobosin A biosynthesis and sexual development in Chaetomium globosum. 2018 PLoS ONE pmid:29652900
Zhu X et al. Penochalasin K, a new unusual chaetoglobosin from the mangrove endophytic fungus Penicillium chrysogenum V11 and its effective semi-synthesis. 2017 Fitoterapia pmid:28958956
Ashrafi S et al. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. 2017 PLoS ONE pmid:28700638
Jiang C et al. Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. 2017 World J. Microbiol. Biotechnol. pmid:28466302
van Haelst C and Rothstein TL Cytochalasin stimulates phosphoinositide metabolism in murine B lymphocytes. 1988 J. Immunol. pmid:2830337
Jiang C et al. New production process of the antifungal chaetoglobosin A using cornstalks. Braz. J. Microbiol. pmid:28223029
Zhao SS et al. Chaetomium globosum CDW7, a potential biological control strain and its antifungal metabolites. 2017 FEMS Microbiol. Lett. pmid:28011695
Jiang T et al. Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. 2016 J. Nat. Prod. pmid:27759375
Chen C et al. Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare. 2015 J. Nat. Prod. pmid:26068802
Dhillon B et al. Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25733908