Chaetoglobosins

Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.

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Introduction

To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Chaetoglobosins

MeSH term MeSH ID Detail
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Chaetoglobosins

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Chaetoglobosins?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Chaetoglobosins?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

What genes are associated with Chaetoglobosins?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Chaetoglobosins

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Authors Title Published Journal PubMed Link
Walsh JP et al. Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. 2019 Rapid Commun. Mass Spectrom. pmid:30325552
Yang MH et al. Aureochaeglobosins A-C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum. 2018 Org. Lett. pmid:29771535
Hu Y et al. Gα-cAMP/PKA pathway positively regulates pigmentation, chaetoglobosin A biosynthesis and sexual development in Chaetomium globosum. 2018 PLoS ONE pmid:29652900
Jiang C et al. Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. 2017 World J. Microbiol. Biotechnol. pmid:28466302
Zhao SS et al. Chaetomium globosum CDW7, a potential biological control strain and its antifungal metabolites. 2017 FEMS Microbiol. Lett. pmid:28011695
Ashrafi S et al. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. 2017 PLoS ONE pmid:28700638
Zhu X et al. Penochalasin K, a new unusual chaetoglobosin from the mangrove endophytic fungus Penicillium chrysogenum V11 and its effective semi-synthesis. 2017 Fitoterapia pmid:28958956
Jiang T et al. Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. 2016 J. Nat. Prod. pmid:27759375
Chen C et al. Armochaetoglobins A-J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare. 2015 J. Nat. Prod. pmid:26068802
Dhillon B et al. Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25733908
Li B et al. Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells. 2015 Cancer Lett. pmid:25304379
Rogers KD et al. Diplodiatoxin, chaetoglobosins, and diplonine associated with a field outbreak of Stenocarpella ear rot in Illinois. 2014 Mycotoxin Res pmid:24504633
Zheng QC et al. Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum. 2014 Fitoterapia pmid:24418656
Trendowski M Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. 2014 Biochim. Biophys. Acta pmid:25286320
Li H et al. Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities. 2014 J. Agric. Food Chem. pmid:24708412
Knudsen PB et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. 2014 Leukemia pmid:24280868
Hua C et al. Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway. 2013 Immunobiology pmid:22739238
Kawahara T et al. New chaetoglobosin derivatives, MBJ-0038, MBJ-0039 and MBJ-0040, isolated from the fungus Chaetomium sp. f24230. 2013 J. Antibiot. pmid:23881215
Ishiuchi K et al. Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis. 2013 J. Am. Chem. Soc. pmid:23611317
Luo H et al. Chaetoglobosin K inhibits tumor angiogenesis through downregulation of vascular epithelial growth factor-binding hypoxia-inducible factor 1α. 2013 Anticancer Drugs pmid:23695013