Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harnly JM et al. | Flavonoid content of U.S. fruits, vegetables, and nuts. | 2006 | J. Agric. Food Chem. | pmid:17177529 |
| Jang YP et al. | Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells. | 2005 May-Jun | Photochem. Photobiol. | pmid:15745429 |
| Fimognari C et al. | In vitro anticancer activity of cyanidin-3-O-beta-glucopyranoside: effects on transformed and non-transformed T lymphocytes. | 2005 Jul-Aug | Anticancer Res. | pmid:16080535 |
| Fedenko VS et al. | [Complexation of cyanidin with cadmium ions in solution]. | 2005 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:16335277 |
| Wallerath T et al. | A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase. | 2005 | Nitric Oxide | pmid:15740983 |
| Duthie SJ et al. | DNA stability and lipid peroxidation in vitamin E-deficient rats in vivo and colon cells in vitro--modulation by the dietary anthocyanin, cyanidin-3-glycoside. | 2005 | Eur J Nutr | pmid:15309415 |
| Irani NG and Grotewold E | Light-induced morphological alteration in anthocyanin-accumulating vacuoles of maize cells. | 2005 | BMC Plant Biol. | pmid:15907203 |
| Shimada S et al. | Anthocyanidin synthase in non-anthocyanin-producing Caryophyllales species. | 2005 | Plant J. | pmid:16359388 |
| Arendt BM et al. | Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial (ISRCTN68505294). | 2005 | Nutr J | pmid:16287499 |
| Garcia-Alonso M et al. | Electron spin resonance spectroscopy studies on the free radical scavenging activity of wine anthocyanins and pyranoanthocyanins. | 2005 | Mol Nutr Food Res | pmid:16254886 |
| Dimitrić Marković JM et al. | Electronic and infrared vibrational analysis of cyanidin-quercetin copigment complex. | 2005 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16257774 |
| Kano M et al. | Antioxidative activity of anthocyanins from purple sweet potato, Ipomoera batatas cultivar Ayamurasaki. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15914919 |
| Morita Y et al. | Japanese morning glory dusky mutants displaying reddish-brown or purplish-gray flowers are deficient in a novel glycosylation enzyme for anthocyanin biosynthesis, UDP-glucose:anthocyanidin 3-O-glucoside-2''-O-glucosyltransferase, due to 4-bp insertions in the gene. | 2005 | Plant J. | pmid:15842621 |
| Honda T et al. | Acylated anthocyanins from the violet-blue flowers of Orychophragonus violaceus. | 2005 | Phytochemistry | pmid:16023157 |
| Larsson J et al. | Expanding the ChemGPS chemical space with natural products. | 2005 | J. Nat. Prod. | pmid:16038536 |
| He YH et al. | [Antioxidant and anti-inflammatory effects of cyanidin from cherries on rat adjuvant-induced arthritis]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16422543 |
| Chen PN et al. | Cyanidin 3-glucoside and peonidin 3-glucoside inhibit tumor cell growth and induce apoptosis in vitro and suppress tumor growth in vivo. | 2005 | Nutr Cancer | pmid:16573384 |
| Kim DO et al. | Sweet and sour cherry phenolics and their protective effects on neuronal cells. | 2005 | J. Agric. Food Chem. | pmid:16366675 |
| Ruiz D et al. | Characterization and quantitation of phenolic compounds in new apricot (Prunus armeniaca L.) varieties. | 2005 | J. Agric. Food Chem. | pmid:16302775 |
| Montefiori M et al. | Pigments in the fruit of red-fleshed kiwifruit (Actinidia chinensis and Actinidia deliciosa). | 2005 | J. Agric. Food Chem. | pmid:16302772 |
| Longo L and Vasapollo G | Anthocyanins from bay (Laurus nobilis L.) berries. | 2005 | J. Agric. Food Chem. | pmid:16190671 |
| Mylnikov SV et al. | Rubus fruit juices affect lipid peroxidation in a Drosophila melanogaster model in vivo. | 2005 | J. Agric. Food Chem. | pmid:16190624 |
| Felgines C et al. | Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans. | 2005 | J. Agric. Food Chem. | pmid:16190623 |
| Longo L et al. | Identification of anthocyanins in Rhamnus alaternus L. berries. | 2005 | J. Agric. Food Chem. | pmid:15740065 |
| Stoner GD et al. | Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days. | 2005 | J Clin Pharmacol | pmid:16172180 |
| Yeh CT and Yen GC | Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells. | 2005 | J. Agric. Food Chem. | pmid:15740068 |
| Al-Farsi M et al. | Comparison of antioxidant activity, anthocyanins, carotenoids, and phenolics of three native fresh and sun-dried date (Phoenix dactylifera L.) varieties grown in Oman. | 2005 | J. Agric. Food Chem. | pmid:16159191 |
| Ichiyanagi T et al. | Extended glucuronidation is another major path of cyanidin 3-O-beta-D-glucopyranoside metabolism in rats. | 2005 | J. Agric. Food Chem. | pmid:16131148 |
| Tian Q et al. | Probing anthocyanin profiles in purple sweet potato cell line (Ipomoea batatas L. Cv. Ayamurasaki) by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry. | 2005 | J. Agric. Food Chem. | pmid:16076141 |
| Punyasiri PA et al. | Preformed and induced chemical resistance of tea leaf against Exobasidium vexans infection. | 2005 | J. Chem. Ecol. | pmid:16222773 |
| Takeda K et al. | Components of protocyanin, a blue pigment from the blue flowers of Centaurea cyanus. | 2005 | Phytochemistry | pmid:16005311 |
| Hou DX et al. | Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. | 2005 | Biochem. Pharmacol. | pmid:15963474 |
| McDougall GJ et al. | Anthocyanins from red wine--their stability under simulated gastrointestinal digestion. | 2005 | Phytochemistry | pmid:16242736 |
| McDougall GJ et al. | Anthocyanin-flavanol condensation products from black currant (Ribes nigrum L.). | 2005 | J. Agric. Food Chem. | pmid:16190645 |
| Habermeyer M et al. | Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity. | 2005 | Chem. Res. Toxicol. | pmid:16167831 |
| Innocenti M et al. | Evaluation of the phenolic content in the aerial parts of different varieties of Cichorium intybus L. | 2005 | J. Agric. Food Chem. | pmid:16076140 |
| Wu X and Prior RL | Identification and characterization of anthocyanins by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in common foods in the United States: vegetables, nuts, and grains. | 2005 | J. Agric. Food Chem. | pmid:15826066 |
| Flamini R | Some advances in the knowledge of grape, wine and distillates chemistry as achieved by mass spectrometry. | 2005 | J Mass Spectrom | pmid:15954164 |
| Berardini N et al. | Screening of mango (Mangifera indica L.) cultivars for their contents of flavonol O- and xanthone C-glycosides, anthocyanins, and pectin. | 2005 | J. Agric. Food Chem. | pmid:15740041 |
| Nakajima T et al. | Insertion and excision of a transposable element governs the red floral phenotype in commercial petunias. | 2005 | Theor. Appl. Genet. | pmid:15731929 |
| Wu X and Prior RL | Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries. | 2005 | J. Agric. Food Chem. | pmid:15796599 |
| Riso P et al. | Effects of blood orange juice intake on antioxidant bioavailability and on different markers related to oxidative stress. | 2005 | J. Agric. Food Chem. | pmid:15713002 |
| Zhang Y et al. | Human tumor cell growth inhibition by nontoxic anthocyanidins, the pigments in fruits and vegetables. | 2005 | Life Sci. | pmid:15680311 |
| Frank T et al. | Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract. | 2005 | J Clin Pharmacol | pmid:15647413 |
| Jayaprakasam B et al. | Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. | 2005 | J. Agric. Food Chem. | pmid:15631504 |
| Ichiyanagi T et al. | Metabolic pathway of cyanidin 3-O-beta-D-glucopyranoside in rats. | 2005 | J. Agric. Food Chem. | pmid:15631521 |
| Russo A et al. | Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-beta-d-glucoside. | 2005 | J. Nutr. Biochem. | pmid:15629238 |
| Aura AM et al. | In vitro metabolism of anthocyanins by human gut microflora. | 2005 | Eur J Nutr | pmid:15309431 |
| Shih PH et al. | Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. | 2005 | Food Chem. Toxicol. | pmid:15964118 |
| Nielsen AH et al. | Flavonoids in flowers of 16 Kalanchoë blossfeldiana varieties. | 2005 | Phytochemistry | pmid:16297414 |