Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang XW et al. | A new sensor for ammonia based on cyanidin-sensitized titanium dioxide film operating at room temperature. | 2013 | Anal. Chim. Acta | pmid:23830444 |
| Bushakra JM et al. | QTL involved in the modification of cyanidin compounds in black and red raspberry fruit. | 2013 | Theor. Appl. Genet. | pmid:23224381 |
| Gharib A et al. | In vitro and in vivo antibacterial activities of cyanidinum chloride-loaded liposomes against a resistant strain of Pseudomonas aeruginosa. | 2013 | Planta Med. | pmid:23203413 |
| Esselen M et al. | Anthocyanins suppress the cleavable complex formation by irinotecan and diminish its DNA-strand-breaking activity in the colon of Wistar rats. | 2013 | Carcinogenesis | pmid:23275152 |
| Jia Y et al. | Cyanidin is an agonistic ligand for peroxisome proliferator-activated receptor-alpha reducing hepatic lipid. | 2013 | Biochim. Biophys. Acta | pmid:23228689 |
| Xiao J et al. | A review on structure-activity relationship of dietary polyphenols inhibiting α-amylase. | 2013 | Crit Rev Food Sci Nutr | pmid:23391016 |
| Gao S et al. | Cyanidin reverses cisplatin-induced apoptosis in HK-2 proximal tubular cells through inhibition of ROS-mediated DNA damage and modulation of the ERK and AKT pathways. | 2013 | Cancer Lett. | pmid:23360684 |
| Tanaka J et al. | Purple rice extract and its constituents suppress endoplasmic reticulum stress-induced retinal damage in vitro and in vivo. | 2013 | Life Sci. | pmid:23123597 |
| Jia Y et al. | Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23769638 |
| Toffali K et al. | Carrot-specific features of the phenylpropanoid pathway identified by feeding cultured cells with defined intermediates. | 2013 | Plant Sci. | pmid:23759106 |
| Kuhn I et al. | Schistosoma mansoni NAD(+) catabolizing enzyme: identification of key residues in catalysis. | 2013 | Biochim. Biophys. Acta | pmid:24035885 |
| Takahama U et al. | Interactions of starch with a cyanidin-catechin pigment (vignacyanidin) isolated from Vigna angularis bean. | 2013 | Food Chem | pmid:23871000 |
| Brugliera F et al. | Violet/blue chrysanthemums--metabolic engineering of the anthocyanin biosynthetic pathway results in novel petal colors. | 2013 | Plant Cell Physiol. | pmid:23926066 |
| Gharib A et al. | Treatment of diabetes in the mouse model by delphinidin and cyanidin hydrochloride in free and liposomal forms. | 2013 | Planta Med. | pmid:24108435 |
| Pompei A et al. | Cyanidin reduces preadipocyte differentiation and relative ChREBP expression. | 2012 Apr-Jun | J. Biol. Regul. Homeost. Agents | pmid:22824753 |
| Wang Y et al. | Antioxidant activities and major anthocyanins of Myrobalan plum (Prunus cerasifera Ehrh.). | 2012 | J. Food Sci. | pmid:22432436 |
| Arya A et al. | Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22474512 |
| Bonarska-Kujawa D et al. | Interaction of selected anthocyanins with erythrocytes and liposome membranes. | 2012 | Cell. Mol. Biol. Lett. | pmid:22396139 |
| Ieri F et al. | Simultaneous determination of anthocyanins, coumarins and phenolic acids in fruits, kernels and liqueur of Prunus mahaleb L. | 2012 | Food Chem | pmid:22980784 |
| Mulabagal V et al. | Quantitative analysis of anthocyanins in Euterpe oleracea (açaÃ) dietary supplement raw materials and capsules by Q-TOF liquid chromatography/mass spectrometry. | 2012 | Pharm Biol | pmid:22900515 |
| Oliveira Lde S et al. | Antioxidant metabolism during fruit development of different acerola (Malpighia emarginata D.C) clones. | 2012 | J. Agric. Food Chem. | pmid:22834960 |
| Kim SM et al. | Neuroprotective effects of black soybean anthocyanins via inactivation of ASK1-JNK/p38 pathways and mobilization of cellular sialic acids. | 2012 | Life Sci. | pmid:22575822 |
| Park WT et al. | Metabolic profiling of glucosinolates, anthocyanins, carotenoids, and other secondary metabolites in kohlrabi (Brassica oleracea var. gongylodes). | 2012 | J. Agric. Food Chem. | pmid:22742768 |
| Li X et al. | Accumulation of phenylpropanoids and correlated gene expression during the development of tartary buckwheat sprouts. | 2012 | J. Agric. Food Chem. | pmid:22587625 |
| Aguayo-Rojas J et al. | Phytochemicals and antioxidant capacity of tortillas obtained after lime-cooking extrusion process of whole pigmented mexican maize. | 2012 | Plant Foods Hum Nutr | pmid:22562094 |
| Wang D et al. | Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice. | 2012 | Mol Nutr Food Res | pmid:22495986 |
| Saito N et al. | Covalent anthocyanin-flavonol complexes from the violet-blue flowers of Allium 'Blue Perfume'. | 2012 | Phytochemistry | pmid:22704652 |
| Hall D et al. | Molecular cloning and biochemical characterization of the UDP-glucose: flavonoid 3-O-glucosyltransferase from Concord grape (Vitis labrusca). | 2012 | Phytochemistry | pmid:22098678 |
| Yang Y et al. | SNARE-wedging polyphenols as small molecular botox. | 2012 | Planta Med. | pmid:22109835 |
| Ernst IM et al. | Cyanidin does not affect sulforaphane-mediated Nrf2 induction in cultured human keratinocytes. | 2012 | Br. J. Nutr. | pmid:21745425 |
| Tatsuzawa F et al. | Triacylated peonidin 3-sophoroside-5-glucosides from the purple flowers of Moricandia ramburii Webb. | 2012 | Phytochemistry | pmid:22264647 |
| Brown PN et al. | Comparisons of large (Vaccinium macrocarpon Ait.) and small (Vaccinium oxycoccos L., Vaccinium vitis-idaea L.) cranberry in British Columbia by phytochemical determination, antioxidant potential, and metabolomic profiling with chemometric analysis. | 2012 | Planta Med. | pmid:22337317 |
| Sun Y et al. | Arabidopsis TT19 functions as a carrier to transport anthocyanin from the cytosol to tonoplasts. | 2012 | Mol Plant | pmid:22201047 |
| Yi L et al. | Differential suppression of intracellular reactive oxygen species-mediated signaling pathway in vascular endothelial cells by several subclasses of flavonoids. | 2012 | Biochimie | pmid:22683914 |
| Ojwang LO et al. | Ultra performance liquid chromatography-tandem quadrupole mass spectrometry profiling of anthocyanins and flavonols in cowpea (Vigna unguiculata) of varying genotypes. | 2012 | J. Agric. Food Chem. | pmid:22429113 |
| Yoshimura Y et al. | Visualization of anthocyanin species in rabbiteye blueberry Vaccinium ashei by matrix-assisted laser desorption/ionization imaging mass spectrometry. | 2012 | Anal Bioanal Chem | pmid:22399120 |
| de Jesus NZ et al. | Tannins, peptic ulcers and related mechanisms. | 2012 | Int J Mol Sci | pmid:22489149 |
| Zhu M et al. | Relationship between the composition of flavonoids and flower colors variation in tropical water lily (Nymphaea) cultivars. | 2012 | PLoS ONE | pmid:22485167 |
| Jang HH et al. | Black rice (Oryza sativa L.) extract attenuates hepatic steatosis in C57BL/6 J mice fed a high-fat diet via fatty acid oxidation. | 2012 | Nutr Metab (Lond) | pmid:22458550 |
| Payyavula RS et al. | Differential effects of environment on potato phenylpropanoid and carotenoid expression. | 2012 | BMC Plant Biol. | pmid:22429339 |
| Aqil F et al. | Antioxidant and antiproliferative activities of anthocyanin/ellagitannin-enriched extracts from Syzygium cumini L. (Jamun, the Indian Blackberry). | 2012 | Nutr Cancer | pmid:22420901 |
| Devi PS et al. | DNA Damage Protecting Activity and Free Radical Scavenging Activity of Anthocyanins from Red Sorghum (Sorghum bicolor) Bran. | 2012 | Biotechnol Res Int | pmid:22400119 |
| Ghanbari R et al. | Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. | 2012 | Int J Mol Sci | pmid:22489153 |
| Roslan ND et al. | Flavonoid biosynthesis genes putatively identified in the aromatic plant Polygonum minus via Expressed Sequences Tag (EST) analysis. | 2012 | Int J Mol Sci | pmid:22489118 |
| Sharif T et al. | Aronia melanocarpa juice induces a redox-sensitive p73-related caspase 3-dependent apoptosis in human leukemia cells. | 2012 | PLoS ONE | pmid:22412883 |
| Arfan M et al. | Antioxidant activity of mulberry fruit extracts. | 2012 | Int J Mol Sci | pmid:22408465 |
| Kanwal S et al. | Docking of human rhodopsin mutant (Gly90→Asp) with beta-arrestin and cyanidin 3-rutinoside to cure night blindness. | 2012 | Bioinformation | pmid:22368384 |
| Yoshimura Y et al. | Different localization patterns of anthocyanin species in the pericarp of black rice revealed by imaging mass spectrometry. | 2012 | PLoS ONE | pmid:22363605 |
| Khater F et al. | Identification and functional characterization of cDNAs coding for hydroxybenzoate/hydroxycinnamate glucosyltransferases co-expressed with genes related to proanthocyanidin biosynthesis. | 2012 | J. Exp. Bot. | pmid:22090445 |
| Yonekura-Sakakibara K et al. | Two glycosyltransferases involved in anthocyanin modification delineated by transcriptome independent component analysis in Arabidopsis thaliana. | 2012 | Plant J. | pmid:21899608 |