Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Stintzing FC et al. | Color and antioxidant properties of cyanidin-based anthocyanin pigments. | 2002 | J. Agric. Food Chem. | pmid:12358498 |
| Matsui T et al. | alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins. | 2001 | J. Agric. Food Chem. | pmid:11308352 |
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| Solomon A et al. | Protection of fibroblasts (NIH-3T3) against oxidative damage by cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). | 2010 | J. Agric. Food Chem. | pmid:20443626 |
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| Tanaka J et al. | Purple rice extract and anthocyanidins of the constituents protect against light-induced retinal damage in vitro and in vivo. | 2011 | J. Agric. Food Chem. | pmid:21175193 |
| Josuttis M et al. | Solar UVB response of bioactives in strawberry (Fragaria × ananassa Duch. L.): a comparison of protected and open-field cultivation. | 2010 | J. Agric. Food Chem. | pmid:21086998 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Zhang Y et al. | Spectral alteration and degradation of cyanidin-3-glucoside exposed to pulsed electric field. | 2010 | J. Agric. Food Chem. | pmid:20163112 |
| Johnson ET et al. | Constitutive expression of the maize genes B1 and C1 in transgenic Hi II maize results in differential tissue pigmentation and generates resistance to Helicoverpa zea. | 2010 | J. Agric. Food Chem. | pmid:20108901 |
| Li X et al. | Purple canola: Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. | 2010 | J. Agric. Food Chem. | pmid:20073469 |
| Asada T and Tamura H | Isolation of bilberry anthocyanidin 3-glycosides bearing ortho-dihydroxyl groups on the B ring by forming an aluminum complex and their antioxidant activity. | 2012 | J. Agric. Food Chem. | pmid:23025407 |
| Stalmach A et al. | Identification of (poly)phenolic compounds in concord grape juice and their metabolites in human plasma and urine after juice consumption. | 2011 | J. Agric. Food Chem. | pmid:21812481 |
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| Pinho C et al. | Optimization of conditions for anthocyanin hydrolysis from red wine using response surface methodology (RSM). | 2011 | J. Agric. Food Chem. | pmid:21158431 |
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| Meiers S et al. | The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. | 2001 | J. Agric. Food Chem. | pmid:11262056 |
| Pricelius S et al. | Substrate specificities of glycosidases from Aspergillus species pectinase preparations on elderberry anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19191672 |
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| You Q et al. | Inhibitory effects of muscadine anthocyanins on α-glucosidase and pancreatic lipase activities. | 2011 | J. Agric. Food Chem. | pmid:21797278 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
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| Montefiori M et al. | Characterization and quantification of anthocyanins in red kiwifruit ( Actinidia spp.). | 2009 | J. Agric. Food Chem. | pmid:19572542 |
| Lätti AK et al. | Characterization of anthocyanins in caucasian blueberries (Vaccinium arctostaphylos L.) native to Turkey. | 2009 | J. Agric. Food Chem. | pmid:19480388 |
| Persson IA et al. | Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. | 2009 | J. Agric. Food Chem. | pmid:19441816 |
| Pawlowska AM et al. | Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits. | 2008 | J. Agric. Food Chem. | pmid:18412362 |
| Bellido GG and Beta T | Anthocyanin composition and oxygen radical scavenging capacity (ORAC) of milled and pearled purple, black, and common barley. | 2009 | J. Agric. Food Chem. | pmid:19159302 |
| Tulio AZ et al. | Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry. | 2008 | J. Agric. Food Chem. | pmid:18290621 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Matsuura R et al. | Determination of antioxidant activity and characterization of antioxidant phenolics in the plum vinegar extract of cherry blossom (Prunus lannesiana). | 2008 | J. Agric. Food Chem. | pmid:18092753 |
| Aaby K et al. | Characterization of phenolic compounds in strawberry (Fragaria x ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity. | 2007 | J. Agric. Food Chem. | pmid:17472391 |
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| Hosseinian FS and Beta T | Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries. | 2007 | J. Agric. Food Chem. | pmid:18052240 |
| Walton MC et al. | The flavonol quercetin-3-glucoside inhibits cyanidin-3-glucoside absorption in vitro. | 2006 | J. Agric. Food Chem. | pmid:16787048 |
| Frank J et al. | Effects of dietary anthocyanins on tocopherols and lipids in rats. | 2002 | J. Agric. Food Chem. | pmid:12452636 |
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| Ichiyanagi T et al. | Extended glucuronidation is another major path of cyanidin 3-O-beta-D-glucopyranoside metabolism in rats. | 2005 | J. Agric. Food Chem. | pmid:16131148 |
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