Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang Y et al. | Antioxidant activities and major anthocyanins of Myrobalan plum (Prunus cerasifera Ehrh.). | 2012 | J. Food Sci. | pmid:22432436 |
| Tanaka J et al. | Purple rice (Oryza sativa L.) extract and its constituents inhibit VEGF-induced angiogenesis. | 2012 | Phytother Res | pmid:21633982 |
| Arapitsas P et al. | A metabolomic approach to the study of wine micro-oxygenation. | 2012 | PLoS ONE | pmid:22662221 |
| Ieri F et al. | Simultaneous determination of anthocyanins, coumarins and phenolic acids in fruits, kernels and liqueur of Prunus mahaleb L. | 2012 | Food Chem | pmid:22980784 |
| Mulabagal V et al. | Quantitative analysis of anthocyanins in Euterpe oleracea (açaÃ) dietary supplement raw materials and capsules by Q-TOF liquid chromatography/mass spectrometry. | 2012 | Pharm Biol | pmid:22900515 |
| Oliveira Lde S et al. | Antioxidant metabolism during fruit development of different acerola (Malpighia emarginata D.C) clones. | 2012 | J. Agric. Food Chem. | pmid:22834960 |
| Kim SM et al. | Neuroprotective effects of black soybean anthocyanins via inactivation of ASK1-JNK/p38 pathways and mobilization of cellular sialic acids. | 2012 | Life Sci. | pmid:22575822 |
| Park WT et al. | Metabolic profiling of glucosinolates, anthocyanins, carotenoids, and other secondary metabolites in kohlrabi (Brassica oleracea var. gongylodes). | 2012 | J. Agric. Food Chem. | pmid:22742768 |
| Schrader C et al. | Genistein as a potential inducer of the anti-atherogenic enzyme paraoxonase-1: studies in cultured hepatocytes in vitro and in rat liver in vivo. | 2012 | J. Cell. Mol. Med. | pmid:22304296 |
| Li X et al. | Accumulation of phenylpropanoids and correlated gene expression during the development of tartary buckwheat sprouts. | 2012 | J. Agric. Food Chem. | pmid:22587625 |
| Aguayo-Rojas J et al. | Phytochemicals and antioxidant capacity of tortillas obtained after lime-cooking extrusion process of whole pigmented mexican maize. | 2012 | Plant Foods Hum Nutr | pmid:22562094 |
| Wang D et al. | Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice. | 2012 | Mol Nutr Food Res | pmid:22495986 |
| Saito N et al. | Covalent anthocyanin-flavonol complexes from the violet-blue flowers of Allium 'Blue Perfume'. | 2012 | Phytochemistry | pmid:22704652 |
| Yuan L et al. | Molecular cloning and characterization of PtrLAR3, a gene encoding leucoanthocyanidin reductase from Populus trichocarpa, and its constitutive expression enhances fungal resistance in transgenic plants. | 2012 | J. Exp. Bot. | pmid:22268151 |
| Zhu W et al. | The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway. | 2012 | Free Radic. Biol. Med. | pmid:22085656 |
| Akhlaghi M and Bandy B | Preconditioning and acute effects of flavonoids in protecting cardiomyocytes from oxidative cell death. | 2012 | Oxid Med Cell Longev | pmid:22829963 |
| Sun Y et al. | Arabidopsis TT19 functions as a carrier to transport anthocyanin from the cytosol to tonoplasts. | 2012 | Mol Plant | pmid:22201047 |
| Su M et al. | Physical changes and physiological characteristics of red and green peel during nectarine (cv. Hu018) maturation. | 2012 | J. Sci. Food Agric. | pmid:22144032 |
| Asada T and Tamura H | Isolation of bilberry anthocyanidin 3-glycosides bearing ortho-dihydroxyl groups on the B ring by forming an aluminum complex and their antioxidant activity. | 2012 | J. Agric. Food Chem. | pmid:23025407 |
| Yi L et al. | Differential suppression of intracellular reactive oxygen species-mediated signaling pathway in vascular endothelial cells by several subclasses of flavonoids. | 2012 | Biochimie | pmid:22683914 |
| Ojwang LO et al. | Ultra performance liquid chromatography-tandem quadrupole mass spectrometry profiling of anthocyanins and flavonols in cowpea (Vigna unguiculata) of varying genotypes. | 2012 | J. Agric. Food Chem. | pmid:22429113 |
| Peng QZ et al. | An integrated approach to demonstrating the ANR pathway of proanthocyanidin biosynthesis in plants. | 2012 | Planta | pmid:22678031 |
| De Rosso M et al. | Study of anthocyanic profiles of twenty-one hybrid grape varieties by liquid chromatography and precursor-ion mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22688043 |
| Shih PH et al. | Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways. | 2012 | J. Agric. Food Chem. | pmid:22364184 |
| Ishiguro K et al. | Functional analysis of Antirrhinum kelloggii flavonoid 3'-hydroxylase and flavonoid 3',5'-hydroxylase genes; critical role in flower color and evolution in the genus Antirrhinum. | 2012 | J. Plant Res. | pmid:21959781 |
| Kamonpatana K et al. | Susceptibility of anthocyanins to ex vivo degradation in human saliva. | 2012 | Food Chem | pmid:22868153 |
| Treutter D et al. | Diversity of phenolic profiles in the fruit skin of Prunus domestica plums and related species. | 2012 | J. Agric. Food Chem. | pmid:23140499 |
| Zhu L et al. | Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. | 2012 | Int J Mol Sci | pmid:22489164 |
| Oloyede FM et al. | Effect of NPK fertilizer on chemical composition of pumpkin (Cucurbita pepo Linn.) seeds. | 2012 | ScientificWorldJournal | pmid:22629204 |
| Guo H et al. | Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. | 2012 | Lipids Health Dis | pmid:22243683 |
| Di Giacomo C et al. | Effect of Treatment with Cyanidin-3-O-β-D-Glucoside on Rat Ischemic/Reperfusion Brain Damage. | 2012 | Evid Based Complement Alternat Med | pmid:23008739 |
| Sorrenti V et al. | Dimethylarginine dimethylaminohydrolase/nitric oxide synthase pathway in liver and kidney: protective effect of cyanidin 3-O-β-D-glucoside on ochratoxin-A toxicity. | 2012 | Toxins (Basel) | pmid:22778905 |
| Li S and Yao J | [Adsorption dynamics study on interactions of pigments and human whole saliva]. | 2012 | Hua Xi Kou Qiang Yi Xue Za Zhi | pmid:22768757 |
| Vauzour D | Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. | 2012 | Oxid Med Cell Longev | pmid:22701758 |
| Rozza AL et al. | Morphologic and pharmacological investigations in the epicatechin gastroprotective effect. | 2012 | Evid Based Complement Alternat Med | pmid:22666296 |
| Mohanty S and Cock IE | The chemotherapeutic potential of Terminalia ferdinandiana: Phytochemistry and bioactivity. | 2012 | Pharmacogn Rev | pmid:22654402 |
| Taha RM and Wafa SN | Plant regeneration and cellular behaviour studies in Celosia cristata grown in vivo and in vitro. | 2012 | ScientificWorldJournal | pmid:22593677 |
| Kumar S et al. | Genomic selection for fruit quality traits in apple (Malus×domestica Borkh.). | 2012 | PLoS ONE | pmid:22574211 |
| Ganugapati J et al. | Molecular docking studies of banana flower flavonoids as insulin receptor tyrosine kinase activators as a cure for diabetes mellitus. | 2012 | Bioinformation | pmid:22493522 |
| Vignolini S et al. | The mirror crack'd: both pigment and structure contribute to the glossy blue appearance of the mirror orchid, Ophrys speculum. | 2012 | New Phytol. | pmid:23043621 |
| Bak MJ et al. | Procyanidins from wild grape (Vitis amurensis) seeds regulate ARE-mediated enzyme expression via Nrf2 coupled with p38 and PI3K/Akt pathway in HepG2 cells. | 2012 | Int J Mol Sci | pmid:22312287 |
| Ibrahim MH et al. | Involvement of nitrogen on flavonoids, glutathione, anthocyanin, ascorbic acid and antioxidant activities of Malaysian medicinal plant Labisia pumila Blume (Kacip Fatimah). | 2012 | Int J Mol Sci | pmid:22312260 |
| Huang WY et al. | Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing. | 2012 | J Zhejiang Univ Sci B | pmid:22302422 |
| Chagné D et al. | QTL and candidate gene mapping for polyphenolic composition in apple fruit. | 2012 | BMC Plant Biol. | pmid:22269060 |
| Han Y et al. | Introduction of apple ANR genes into tobacco inhibits expression of both CHI and DFR genes in flowers, leading to loss of anthocyanin. | 2012 | J. Exp. Bot. | pmid:22238451 |
| Sun CD et al. | Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic β cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice. | 2012 | J Med Food | pmid:22181073 |
| Khater F et al. | Identification and functional characterization of cDNAs coding for hydroxybenzoate/hydroxycinnamate glucosyltransferases co-expressed with genes related to proanthocyanidin biosynthesis. | 2012 | J. Exp. Bot. | pmid:22090445 |
| Duchnowicz P et al. | Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study). | 2012 | Eur J Nutr | pmid:21755326 |
| Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |
| Biegelmeyer R et al. | Comparative analysis of the chemical composition and antioxidant activity of red (Psidium cattleianum) and yellow (Psidium cattleianum var. lucidum) strawberry guava fruit. | 2011 | J. Food Sci. | pmid:22417549 |