Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim JM et al. | Effects of black soybean [Glycine max (L.) Merr.] seed coats and its anthocyanidins on colonic inflammation and cell proliferation in vitro and in vivo. | 2008 | J. Agric. Food Chem. | pmid:18710248 |
| Strugała P et al. | Interaction between Mimic Lipid Membranes and Acylated and Nonacylated Cyanidin and Its Bioactivity. | 2016 | J. Agric. Food Chem. | pmid:27624410 |
| Mertens-Talcott SU et al. | Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. | 2008 | J. Agric. Food Chem. | pmid:18693743 |
| Cheng JC et al. | Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. | 2009 | J. Agric. Food Chem. | pmid:19807153 |
| Solomon A et al. | Protection of fibroblasts (NIH-3T3) against oxidative damage by cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). | 2010 | J. Agric. Food Chem. | pmid:20443626 |
| Esselen M et al. | Anthocyanin-rich blackberry extract suppresses the DNA-damaging properties of topoisomerase I and II poisons in colon carcinoma cells. | 2011 | J. Agric. Food Chem. | pmid:21599019 |
| Xue YL et al. | Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki. | 2011 | J. Agric. Food Chem. | pmid:21568325 |
| Sentandreu E et al. | LC-DAD-ESI/MS(n) determination of direct condensation flavanol-anthocyanin adducts in pressure extracted pomegranate (Punica granatum L.) juice. | 2010 | J. Agric. Food Chem. | pmid:20839870 |
| Gill CI et al. | Profiling of phenols in human fecal water after raspberry supplementation. | 2010 | J. Agric. Food Chem. | pmid:20809621 |
| Montilla EC et al. | Preparative isolation of anthocyanins from Japanese purple sweet potato (Ipomoea batatas L.) varieties by high-speed countercurrent chromatography. | 2010 | J. Agric. Food Chem. | pmid:20731350 |
| Schauss AG et al. | Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (acai). | 2006 | J. Agric. Food Chem. | pmid:17061839 |
| Slavin M et al. | Antioxidant properties, phytochemical composition, and antiproliferative activity of Maryland-grown soybeans with colored seed coats. | 2009 | J. Agric. Food Chem. | pmid:19950996 |
| Slimestad R et al. | Analysis of phenolic compounds in six Norwegian plum cultivars (Prunus domestica L.). | 2009 | J. Agric. Food Chem. | pmid:19888727 |
| Moze S et al. | Phenolics in Slovenian bilberries ( Vaccinium myrtillus L.) and blueberries ( Vaccinium corymbosum L.). | 2011 | J. Agric. Food Chem. | pmid:21574578 |
| He J et al. | Stability of black raspberry anthocyanins in the digestive tract lumen and transport efficiency into gastric and small intestinal tissues in the rat. | 2009 | J. Agric. Food Chem. | pmid:19317488 |
| Harb J et al. | Correlation between changes in polyphenol composition of peels and incidence of COâ‚‚ skin burning of 'Cameo' apples as influenced by controlled atmosphere storage. | 2013 | J. Agric. Food Chem. | pmid:23517081 |
| Sreerama YN et al. | Variability in the distribution of phenolic compounds in milled fractions of chickpea and horse gram: evaluation of their antioxidant properties. | 2010 | J. Agric. Food Chem. | pmid:20593828 |
| Deng J et al. | Comparative study on iron release from soybean (Glycine max) seed ferritin induced by anthocyanins and ascorbate. | 2010 | J. Agric. Food Chem. | pmid:19921836 |
| Queiroz F et al. | Degradation of anthocyanins and anthocyanidins in blueberry jams/stuffed fish. | 2009 | J. Agric. Food Chem. | pmid:19845348 |
| Song W et al. | Phytochemical profiles of different mulberry (Morus sp.) species from China. | 2009 | J. Agric. Food Chem. | pmid:19761189 |
| Liu L et al. | Degradation of cyanidin 3-rutinoside in the presence of (-)-epicatechin and litchi pericarp polyphenol oxidase. | 2007 | J. Agric. Food Chem. | pmid:17914871 |
| Mulabagal V et al. | Cultivars of apple fruits that are not marketed with potential for anthocyanin production. | 2007 | J. Agric. Food Chem. | pmid:17822290 |
| Solomon A et al. | Antioxidant activities and anthocyanin content of fresh fruits of common fig (Ficus carica L.). | 2006 | J. Agric. Food Chem. | pmid:17002444 |
| Fang Z et al. | Chemical composition of clarified bayberry (Myrica rubra Sieb. et Zucc.) juice sediment. | 2006 | J. Agric. Food Chem. | pmid:17002443 |
| de Brito ES et al. | Anthocyanins present in selected tropical fruits: acerola, jambolão, jussara, and guajiru. | 2007 | J. Agric. Food Chem. | pmid:17929888 |
| Ruiz D et al. | Characterization and quantitation of phenolic compounds in new apricot (Prunus armeniaca L.) varieties. | 2005 | J. Agric. Food Chem. | pmid:16302775 |
| Li L et al. | Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | 2009 | J. Agric. Food Chem. | pmid:19166352 |
| Montefiori M et al. | Pigments in the fruit of red-fleshed kiwifruit (Actinidia chinensis and Actinidia deliciosa). | 2005 | J. Agric. Food Chem. | pmid:16302772 |
| Cortell JM and Kennedy JA | Effect of shading on accumulation of flavonoid compounds in (Vitis vinifera L.) pinot noir fruit and extraction in a model system. | 2006 | J. Agric. Food Chem. | pmid:17061828 |
| Longo L et al. | Identification of anthocyanins in Rhamnus alaternus L. berries. | 2005 | J. Agric. Food Chem. | pmid:15740065 |
| Yeh CT and Yen GC | Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells. | 2005 | J. Agric. Food Chem. | pmid:15740068 |
| Scordino M et al. | Adsorption of flavonoids on resins: cyanidin 3-glucoside. | 2004 | J. Agric. Food Chem. | pmid:15053537 |
| Wu X and Prior RL | Identification and characterization of anthocyanins by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in common foods in the United States: vegetables, nuts, and grains. | 2005 | J. Agric. Food Chem. | pmid:15826066 |
| Berardini N et al. | Screening of mango (Mangifera indica L.) cultivars for their contents of flavonol O- and xanthone C-glycosides, anthocyanins, and pectin. | 2005 | J. Agric. Food Chem. | pmid:15740041 |
| Jordheim M et al. | Characterization of hemiacetal forms of anthocyanidin 3-O-beta-glycopyranosides. | 2006 | J. Agric. Food Chem. | pmid:17147416 |
| Wu X and Prior RL | Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries. | 2005 | J. Agric. Food Chem. | pmid:15796599 |
| Romero C et al. | Polyphenol changes during fermentation of naturally black olives. | 2004 | J. Agric. Food Chem. | pmid:15053538 |
| Kuskoski EM et al. | Characterization of anthocyanins from the fruits of baguaçu (Eugenia umbelliflora Berg). | 2003 | J. Agric. Food Chem. | pmid:12926896 |
| Del Pozo-Insfran D et al. | Phytochemical composition and pigment stability of Açai (Euterpe oleracea Mart.). | 2004 | J. Agric. Food Chem. | pmid:15030208 |
| Yousef GG et al. | Biosynthesis and characterization of 14C-enriched flavonoid fractions from plant cell suspension cultures. | 2004 | J. Agric. Food Chem. | pmid:14995111 |
| Chaovanalikit A et al. | Characterization and quantification of anthocyanins and polyphenolics in bluehHoneysuckle (Lonicera caerulea L.). | 2004 | J. Agric. Food Chem. | pmid:14969540 |
| Slimestad R and Solheim H | Anthocyanins from black currants (Ribes nigrum L.). | 2002 | J. Agric. Food Chem. | pmid:12009991 |
| Seeram NP et al. | Characterization, quantification, and bioactivities of anthocyanins in Cornus species. | 2002 | J. Agric. Food Chem. | pmid:11958615 |
| Hu C et al. | Black rice (Oryza sativa L. indica) pigmented fraction suppresses both reactive oxygen species and nitric oxide in chemical and biological model systems. | 2003 | J. Agric. Food Chem. | pmid:12926869 |
| Gonnet JF | Origin of the color of Cv. rhapsody in blue rose and some other so-called "blue" roses. | 2003 | J. Agric. Food Chem. | pmid:12903958 |
| Es-Safi NE et al. | Interactions between cyanidin 3-O-glucoside and furfural derivatives and their impact on food color changes. | 2002 | J. Agric. Food Chem. | pmid:12236682 |
| Lehtonen HM et al. | Urinary excretion of the main anthocyanin in lingonberry (Vaccinium vitis-idaea), cyanidin 3-O-galactoside, and its metabolites. | 2009 | J. Agric. Food Chem. | pmid:19351112 |
| Redus M et al. | Rate and equilibrium constants for the dehydration and deprotonation reactions of some monoacylated and glycosylated cyanidin derivatives. | 1999 | J. Agric. Food Chem. | pmid:10552670 |
| Seeram NP et al. | Degradation products of cyanidin glycosides from tart cherries and their bioactivities. | 2001 | J. Agric. Food Chem. | pmid:11600045 |
| Wang SY and Zheng W | Effect of plant growth temperature on antioxidant capacity in strawberry. | 2001 | J. Agric. Food Chem. | pmid:11600054 |