Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Terahara N et al. | Functional new acylated sophoroses and deglucosylated anthocyanins in a fermented red vinegar. | 2009 | J. Agric. Food Chem. | pmid:19702267 |
| Hugueney P et al. | A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine. | 2009 | Plant Physiol. | pmid:19525322 |
| Rajani GP and Ashok P | In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. | 2009 | Indian J Pharmacol | pmid:20177495 |
| Tanaka T et al. | Chemistry of secondary polyphenols produced during processing of tea and selected foods. | 2009 | Int J Mol Sci | pmid:20161999 |
| Zikri NN et al. | Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. | 2009 | Nutr Cancer | pmid:20155622 |
| Lee SJ et al. | Grape skin improves antioxidant capacity in rats fed a high fat diet. | 2009 | Nutr Res Pract | pmid:20098580 |
| Payyavula RS et al. | Glycosylation-mediated phenylpropanoid partitioning in Populus tremuloides cell cultures. | 2009 | BMC Plant Biol. | pmid:20040108 |
| Chen G et al. | Cyanidin-3-glucoside reverses ethanol-induced inhibition of neurite outgrowth: role of glycogen synthase kinase 3 Beta. | 2009 | Neurotox Res | pmid:19384566 |
| Kay CD et al. | The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products. | 2009 | Mol Nutr Food Res | pmid:19415657 |
| Sutela S et al. | Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch. | 2009 | BMC Plant Biol. | pmid:19788757 |
| Auger B et al. | Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed. | 2009 | Planta | pmid:19760260 |
| Rubin G et al. | Members of the LBD family of transcription factors repress anthocyanin synthesis and affect additional nitrogen responses in Arabidopsis. | 2009 | Plant Cell | pmid:19933203 |
| Han SJ et al. | Metabolism of cyanidin-3-O-beta-D-glucoside isolated from black colored rice and its antiscratching behavioral effect in mice. | 2009 | J. Food Sci. | pmid:19799667 |
| Moraga AR et al. | Cloning and characterization of a glucosyltransferase from Crocus sativus stigmas involved in flavonoid glucosylation. | 2009 | BMC Plant Biol. | pmid:19695093 |
| Zhao J and Dixon RA | MATE transporters facilitate vacuolar uptake of epicatechin 3'-O-glucoside for proanthocyanidin biosynthesis in Medicago truncatula and Arabidopsis. | 2009 | Plant Cell | pmid:19684242 |
| Philpott M et al. | Dietary protection against free radicals: a case for multiple testing to establish structure-activity relationships for antioxidant potential of anthocyanic plant species. | 2009 | Int J Mol Sci | pmid:19399239 |
| Harding SA et al. | A comparative analysis of phenylpropanoid metabolism, N utilization, and carbon partitioning in fast- and slow-growing Populus hybrid clones. | 2009 | J. Exp. Bot. | pmid:19516073 |
| Cheng JC et al. | Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. | 2009 | J. Agric. Food Chem. | pmid:19807153 |
| Nunn AV et al. | Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? | 2009 | Nutr Metab (Lond) | pmid:19371409 |
| Peel GJ et al. | The LAP1 MYB transcription factor orchestrates anthocyanidin biosynthesis and glycosylation in Medicago. | 2009 | Plant J. | pmid:19368693 |
| Gomez C et al. | Grapevine MATE-type proteins act as vacuolar H+-dependent acylated anthocyanin transporters. | 2009 | Plant Physiol. | pmid:19297587 |
| Ugalde CM et al. | Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers. | 2009 | Pharm. Res. | pmid:19137418 |
| Adisakwattana S et al. | alpha-Glucosidase inhibitory activity of cyanidin-3-galactoside and synergistic effect with acarbose. | 2009 | J Enzyme Inhib Med Chem | pmid:18615280 |
| Slavin M et al. | Antioxidant properties, phytochemical composition, and antiproliferative activity of Maryland-grown soybeans with colored seed coats. | 2009 | J. Agric. Food Chem. | pmid:19950996 |
| Slimestad R et al. | Analysis of phenolic compounds in six Norwegian plum cultivars (Prunus domestica L.). | 2009 | J. Agric. Food Chem. | pmid:19888727 |
| Qin C et al. | Separation and elucidation of anthocyanins in the fruit of mockstrawberry (Duchesnea indica Focke). | 2009 | Nat. Prod. Res. | pmid:19851924 |
| Yuan Y et al. | Transcriptional regulation of anthocyanin biosynthesis in red cabbage. | 2009 | Planta | pmid:19756724 |
| Shin DY et al. | Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723048 |
| Gargouri M et al. | Structure and epimerase activity of anthocyanidin reductase from Vitis vinifera. | 2009 | Acta Crystallogr. D Biol. Crystallogr. | pmid:19690377 |
| Simões C et al. | Anthocyanin production in callus cultures of Cleome rosea: modulation by culture conditions and characterization of pigments by means of HPLC-DAD/ESIMS. | 2009 | Plant Physiol. Biochem. | pmid:19589687 |
| Butryee C et al. | Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf. | 2009 | Int J Food Sci Nutr | pmid:19572229 |
| Li JB et al. | A new acylated anthocyanin from the red flowers of Camellia hongkongensis and characterization of anthocyanins in the section Camellia species. | 2009 | J Integr Plant Biol | pmid:19522813 |
| Nakabayashi R et al. | Metabolomics-oriented isolation and structure elucidation of 37 compounds including two anthocyanins from Arabidopsis thaliana. | 2009 | Phytochemistry | pmid:19497599 |
| Jin J et al. | Analysis of phytochemical composition and chemoprotective capacity of rocket (Eruca sativa and Diplotaxis tenuifolia) leafy salad following cultivation in different environments. | 2009 | J. Agric. Food Chem. | pmid:19489541 |
| Qiu F et al. | Preparative isolation and purification of anthocyanins from purple sweet potato by high-speed counter-current chromatography. | 2009 | J Sep Sci | pmid:19479751 |
| Savikin K et al. | Phenolic content and radical scavenging capacity of berries and related jams from certificated area in Serbia. | 2009 | Plant Foods Hum Nutr | pmid:19468835 |
| Jordheim M et al. | Acylated anthocyanins in inflorescence of spider flower (Cleome hassleriana). | 2009 | Phytochemistry | pmid:19427007 |
| Dreiseitel A et al. | Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B. | 2009 | Pharmacol. Res. | pmid:19416630 |
| Garzón GA et al. | Determination of anthocyanins, total phenolic content, and antioxidant activity in Andes Berry (Rubus glaucus Benth). | 2009 | J. Food Sci. | pmid:19397707 |
| Marczylo TH et al. | Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice. | 2009 | Cancer Chemother. Pharmacol. | pmid:19363608 |
| Kim SH et al. | Structural identification and antioxidant properties of major anthocyanin extracted from Omija (Schizandra chinensis) fruit. | 2009 | J. Food Sci. | pmid:19323727 |
| He J et al. | Stability of black raspberry anthocyanins in the digestive tract lumen and transport efficiency into gastric and small intestinal tissues in the rat. | 2009 | J. Agric. Food Chem. | pmid:19317488 |
| Osmani SA et al. | Effect of glucuronosylation on anthocyanin color stability. | 2009 | J. Agric. Food Chem. | pmid:19281238 |
| Dai J et al. | A comprehensive study of anthocyanin-containing extracts from selected blackberry cultivars: extraction methods, stability, anticancer properties and mechanisms. | 2009 | Food Chem. Toxicol. | pmid:19271318 |
| Kassim A et al. | Environmental and seasonal influences on red raspberry anthocyanin antioxidant contents and identification of quantitative traits loci (QTL). | 2009 | Mol Nutr Food Res | pmid:19156716 |
| Vasco C et al. | Phenolic compounds in Rosaceae fruits from Ecuador. | 2009 | J. Agric. Food Chem. | pmid:19143537 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
| Queiroz F et al. | Degradation of anthocyanins and anthocyanidins in blueberry jams/stuffed fish. | 2009 | J. Agric. Food Chem. | pmid:19845348 |
| Vasco C et al. | Chemical composition and phenolic compound profile of mortiño (Vaccinium floribundum Kunth). | 2009 | J. Agric. Food Chem. | pmid:19719139 |
| Dreiseitel A et al. | sPhospholipase A(2) is inhibited by anthocyanidins. | 2009 | J Neural Transm (Vienna) | pmid:19649692 |
| Montefiori M et al. | Characterization and quantification of anthocyanins in red kiwifruit ( Actinidia spp.). | 2009 | J. Agric. Food Chem. | pmid:19572542 |
| Lätti AK et al. | Characterization of anthocyanins in caucasian blueberries (Vaccinium arctostaphylos L.) native to Turkey. | 2009 | J. Agric. Food Chem. | pmid:19480388 |
| Persson IA et al. | Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. | 2009 | J. Agric. Food Chem. | pmid:19441816 |
| Matsunaga N et al. | Bilberry and its main constituents have neuroprotective effects against retinal neuronal damage in vitro and in vivo. | 2009 | Mol Nutr Food Res | pmid:19415665 |
| Thomasset S et al. | Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? | 2009 | Cancer Chemother. Pharmacol. | pmid:19294386 |
| Song W et al. | Phytochemical profiles of different mulberry (Morus sp.) species from China. | 2009 | J. Agric. Food Chem. | pmid:19761189 |
| Comeskey DJ et al. | Isolation and structural identification of the anthocyanin components of red kiwifruit. | 2009 | J. Agric. Food Chem. | pmid:19203266 |
| Bellido GG and Beta T | Anthocyanin composition and oxygen radical scavenging capacity (ORAC) of milled and pearled purple, black, and common barley. | 2009 | J. Agric. Food Chem. | pmid:19159302 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Knaup B et al. | Anthocyanins as lipoxygenase inhibitors. | 2009 | Mol Nutr Food Res | pmid:19072887 |
| Singh K et al. | Differential display mediated cloning of anthocyanidin reductase gene from tea (Camellia sinensis) and its relationship with the concentration of epicatechins. | 2009 | Tree Physiol. | pmid:19380395 |
| Garcia-Alonso M et al. | Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. | 2009 | J. Nutr. Biochem. | pmid:18789665 |
| Tanaka Y et al. | Recent progress of flower colour modification by biotechnology. | 2009 | Int J Mol Sci | pmid:20054474 |
| Korte G et al. | An examination of anthocyanins' and anthocyanidins' affinity for cannabinoid receptors. | 2009 | J Med Food | pmid:20041802 |
| Ikegami A et al. | Molecular identification of 1-Cys peroxiredoxin and anthocyanidin/flavonol 3-O-galactosyltransferase from proanthocyanidin-rich young fruits of persimmon (Diospyros kaki Thunb.). | 2009 | Planta | pmid:19641937 |
| Zhang Y et al. | The potato R locus codes for dihydroflavonol 4-reductase. | 2009 | Theor. Appl. Genet. | pmid:19588118 |
| Albert NW et al. | Light-induced vegetative anthocyanin pigmentation in Petunia. | 2009 | J. Exp. Bot. | pmid:19380423 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Li L et al. | Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | 2009 | J. Agric. Food Chem. | pmid:19166352 |
| Matus JT et al. | Post-veraison sunlight exposure induces MYB-mediated transcriptional regulation of anthocyanin and flavonol synthesis in berry skins of Vitis vinifera. | 2009 | J. Exp. Bot. | pmid:19129169 |
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| Deluc LG et al. | Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay. | 2009 | BMC Genomics | pmid:19426499 |
| Lehtonen HM et al. | Urinary excretion of the main anthocyanin in lingonberry (Vaccinium vitis-idaea), cyanidin 3-O-galactoside, and its metabolites. | 2009 | J. Agric. Food Chem. | pmid:19351112 |
| Lea MA et al. | Inhibition of growth and induction of differentiation of colon cancer cells by peach and plum phenolic compounds. | 2008 Jul-Aug | Anticancer Res. | pmid:18751377 |
| Fedenko VS | [Cyanidin as endogenous chelator of metal ions in maize seedling roots]. | 2008 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:18710034 |
| Li CY et al. | Corn husk as a potential source of anthocyanins. | 2008 | J. Agric. Food Chem. | pmid:19007127 |
| Laitinen RA et al. | Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida. | 2008 | J. Exp. Bot. | pmid:18725377 |
| Gastrointestinal pharmacology. | 2008 | Indian J Pharmacol | pmid:21593966 | |
| Merzlyak MN et al. | Light absorption by anthocyanins in juvenile, stressed, and senescing leaves. | 2008 | J. Exp. Bot. | pmid:18796701 |
| Xu F et al. | Molecular cloning and function analysis of an anthocyanidin synthase gene from Ginkgo biloba, and its expression in abiotic stress responses. | 2008 | Mol. Cells | pmid:18779661 |
| Zhang G et al. | Structure-dependent photodegradation of carotenoids accelerated by dimethyl tetrasulfide under UVA irradiation. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685214 |
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| Dancs G et al. | The effects of enhanced methionine synthesis on amino acid and anthocyanin content of potato tubers. | 2008 | BMC Plant Biol. | pmid:18549488 |
| Hassimotto NM et al. | Absorption and metabolism of cyanidin-3-glucoside and cyanidin-3-rutinoside extracted from wild mulberry (Morus nigra L.) in rats. | 2008 | Nutr Res | pmid:19083408 |
| Hassimotto NM et al. | Antioxidant status in humans after consumption of blackberry (Rubus fruticosus L.) juices with and without defatted milk. | 2008 | J. Agric. Food Chem. | pmid:19053224 |
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| Pawlowska AM et al. | Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits. | 2008 | J. Agric. Food Chem. | pmid:18412362 |
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| Tulio AZ et al. | Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry. | 2008 | J. Agric. Food Chem. | pmid:18290621 |
| Guo H et al. | Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-alpha-induced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation. | 2008 | Biochem. Pharmacol. | pmid:18179781 |
| Scalzo J et al. | The anthocyanin composition of different Vaccinium, Ribes and Rubus genotypes. | 2008 | Biofactors | pmid:19706968 |
| Ku CS and Mun SP | Optimization of the extraction of anthocyanin from Bokbunja (Rubus coreanus Miq.) marc produced during traditional wine processing and characterization of the extracts. | 2008 | Bioresour. Technol. | pmid:18456493 |
| Wang CY et al. | Increasing antioxidant activity and reducing decay of blueberries by essential oils. | 2008 | J. Agric. Food Chem. | pmid:18442248 |
| Nakatsuka T et al. | Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian. | 2008 | J. Exp. Bot. | pmid:18375606 |
| Maruyama C et al. | Azuki bean juice lowers serum triglyceride concentrations in healthy young women. | 2008 | J Clin Biochem Nutr | pmid:18648655 |
| Griesser M et al. | Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle. | 2008 | J. Exp. Bot. | pmid:18487633 |
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