Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jaakola L et al. | A SQUAMOSA MADS box gene involved in the regulation of anthocyanin accumulation in bilberry fruits. | 2010 | Plant Physiol. | pmid:20566708 |
| Fusi E et al. | Alpha-tocopherol counteracts the cytotoxicity induced by ochratoxin a in primary porcine fibroblasts. | 2010 | Toxins (Basel) | pmid:22069637 |
| Hirai S et al. | Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies. | 2010 | Mediators Inflamm. | pmid:20508825 |
| Min SW et al. | Anti-inflammatory effects of black rice, cyanidin-3-O-beta-D-glycoside, and its metabolites, cyanidin and protocatechuic acid. | 2010 | Int. Immunopharmacol. | pmid:20669401 |
| Ozen T and Türkekul I | Antioxidant activities of Sarcodon imbricatum wildly grown in the Black Sea Region of Turkey. | 2010 | Pharmacogn Mag | pmid:20668572 |
| Titta L et al. | Blood orange juice inhibits fat accumulation in mice. | 2010 | Int J Obes (Lond) | pmid:20029381 |
| Morant M et al. | Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2. | 2010 | Mol Plant | pmid:20008451 |
| Hoorens B et al. | Neighbour identity hardly affects litter-mixture effects on decomposition rates of New Zealand forest species. | 2010 | Oecologia | pmid:19756760 |
| Wiczkowski W et al. | Bioavailability of cyanidin glycosides from natural chokeberry (Aronia melanocarpa) juice with dietary-relevant dose of anthocyanins in humans. | 2010 | J. Agric. Food Chem. | pmid:21067240 |
| Liu J et al. | Bog bilberry (Vaccinium uliginosum L.) extract reduces cultured Hep-G2, Caco-2, and 3T3-L1 cell viability, affects cell cycle progression, and has variable effects on membrane permeability. | 2010 | J. Food Sci. | pmid:20492295 |
| Li Z et al. | Effects of exogenous abscisic acid on yield, antioxidant capacities, and phytochemical contents of greenhouse grown lettuces. | 2010 | J. Agric. Food Chem. | pmid:20420437 |
| Zhang Y et al. | Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. | 2010 | Inflamm. Res. | pmid:20309718 |
| Delazar A et al. | Isolation and free-radical-scavenging properties of cyanidin 3-O-glycosides from the fruits of Ribes biebersteinii Berl. | 2010 | Acta Pharm | pmid:20228037 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Felgines C et al. | Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse. | 2010 | Br. J. Nutr. | pmid:20187984 |
| Choi JY et al. | Analysis and tentative structure elucidation of new anthocyanins in fruit peel of Vitis coignetiae Pulliat (meoru) using LC-MS/MS: Contribution to the overall antioxidant activity. | 2010 | J Sep Sci | pmid:20187032 |
| Zhang Y et al. | Spectral alteration and degradation of cyanidin-3-glucoside exposed to pulsed electric field. | 2010 | J. Agric. Food Chem. | pmid:20163112 |
| Lacombe A et al. | Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7. | 2010 | Int. J. Food Microbiol. | pmid:20153540 |
| Tarozzi A et al. | Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25-35) oligomer-induced toxicity. | 2010 | Neurosci. Lett. | pmid:20152881 |
| Yamagishi M et al. | Two R2R3-MYB genes, homologs of Petunia AN2, regulate anthocyanin biosyntheses in flower Tepals, tepal spots and leaves of asiatic hybrid lily. | 2010 | Plant Cell Physiol. | pmid:20118109 |
| Behnke K et al. | RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. | 2010 | Plant Mol. Biol. | pmid:20526857 |
| Johnson ET et al. | Constitutive expression of the maize genes B1 and C1 in transgenic Hi II maize results in differential tissue pigmentation and generates resistance to Helicoverpa zea. | 2010 | J. Agric. Food Chem. | pmid:20108901 |
| Tsao R | Chemistry and biochemistry of dietary polyphenols. | 2010 | Nutrients | pmid:22254006 |
| Kim CY et al. | The sweet potato IbMYB1 gene as a potential visible marker for sweet potato intragenic vector system. | 2010 | Physiol Plant | pmid:20163556 |
| Akkarachiyasit S et al. | Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase. | 2010 | Int J Mol Sci | pmid:20957102 |
| Yang Y et al. | Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21135223 |
| Matsunaga N et al. | Inhibitory actions of bilberry anthocyanidins on angiogenesis. | 2010 | Phytother Res | pmid:19496063 |
| Chiu LW et al. | The purple cauliflower arises from activation of a MYB transcription factor. | 2010 | Plant Physiol. | pmid:20855520 |
| Ono E et al. | Functional differentiation of the glycosyltransferases that contribute to the chemical diversity of bioactive flavonol glycosides in grapevines (Vitis vinifera). | 2010 | Plant Cell | pmid:20693356 |
| Takahashi R et al. | A new allele of flower color gene W1 encoding flavonoid 3'5'-hydroxylase is responsible for light purple flowers in wild soybean Glycine soja. | 2010 | BMC Plant Biol. | pmid:20663233 |
| Zhao Q et al. | Anthocyanins profile of grape berries of Vitis amurensis, its hybrids and their wines. | 2010 | Int J Mol Sci | pmid:20559511 |
| Boase MR et al. | Isolation and antisense suppression of flavonoid 3', 5'-hydroxylase modifies flower pigments and colour in cyclamen. | 2010 | BMC Plant Biol. | pmid:20540805 |
| de Pascual-Teresa S et al. | Flavanols and anthocyanins in cardiovascular health: a review of current evidence. | 2010 | Int J Mol Sci | pmid:20480037 |
| Cvorovic J et al. | Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells. | 2010 | Arch. Biochem. Biophys. | pmid:20494645 |
| Matsunaga N et al. | Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In Vivo. | 2010 | Evid Based Complement Alternat Med | pmid:18955266 |
| Bedon F et al. | Subgroup 4 R2R3-MYBs in conifer trees: gene family expansion and contribution to the isoprenoid- and flavonoid-oriented responses. | 2010 | J. Exp. Bot. | pmid:20732878 |
| Gutha LR et al. | Modulation of flavonoid biosynthetic pathway genes and anthocyanins due to virus infection in grapevine (Vitis vinifera L.) leaves. | 2010 | BMC Plant Biol. | pmid:20731850 |
| Pandey KB and Rizvi SI | Plant polyphenols as dietary antioxidants in human health and disease. | 2009 Nov-Dec | Oxid Med Cell Longev | pmid:20716914 |
| Burdulis D et al. | Comparative study of anthocyanin composition, antimicrobial and antioxidant activity in bilberry (Vaccinium myrtillus L.) and blueberry (Vaccinium corymbosum L.) fruits. | 2009 Jul-Aug | Acta Pol Pharm | pmid:19702172 |
| Hugueney P et al. | A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine. | 2009 | Plant Physiol. | pmid:19525322 |
| Bjorøy O et al. | C-glycosylanthocyanidins synthesized from C-glycosylflavones. | 2009 | Phytochemistry | pmid:19185884 |
| Gargouri M et al. | Binding-equilibrium and kinetic studies of anthocyanidin reductase from Vitis vinifera. | 2009 | Arch. Biochem. Biophys. | pmid:19772852 |
| Harding SA et al. | A comparative analysis of phenylpropanoid metabolism, N utilization, and carbon partitioning in fast- and slow-growing Populus hybrid clones. | 2009 | J. Exp. Bot. | pmid:19516073 |
| Qiu F et al. | Preparative isolation and purification of anthocyanins from purple sweet potato by high-speed counter-current chromatography. | 2009 | J Sep Sci | pmid:19479751 |
| Savikin K et al. | Phenolic content and radical scavenging capacity of berries and related jams from certificated area in Serbia. | 2009 | Plant Foods Hum Nutr | pmid:19468835 |
| Persson IA et al. | Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. | 2009 | J. Agric. Food Chem. | pmid:19441816 |
| Garcia-Alonso M et al. | Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. | 2009 | J. Nutr. Biochem. | pmid:18789665 |
| Korte G et al. | An examination of anthocyanins' and anthocyanidins' affinity for cannabinoid receptors. | 2009 | J Med Food | pmid:20041802 |
| Zhang Y et al. | The potato R locus codes for dihydroflavonol 4-reductase. | 2009 | Theor. Appl. Genet. | pmid:19588118 |