Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Rubin G et al. | Members of the LBD family of transcription factors repress anthocyanin synthesis and affect additional nitrogen responses in Arabidopsis. | 2009 | Plant Cell | pmid:19933203 |
| Slavin M et al. | Antioxidant properties, phytochemical composition, and antiproliferative activity of Maryland-grown soybeans with colored seed coats. | 2009 | J. Agric. Food Chem. | pmid:19950996 |
| Chakraborty M et al. | Effect of the novel radiant zone drying method on anthocyanins and phenolics of three blueberry liquids. | 2010 | J. Agric. Food Chem. | pmid:19954224 |
| Wang SC et al. | Aqueous Extract from Hibiscus sabdariffa Linnaeus Ameliorate Diabetic Nephropathy via Regulating Oxidative Status and Akt/Bad/14-3-3γ in an Experimental Animal Model. | 2011 | Evid Based Complement Alternat Med | pmid:19965962 |
| Lätti AK et al. | Anthocyanin and flavonol variation in bog bilberries (Vaccinium uliginosum L.) in Finland. | 2010 | J. Agric. Food Chem. | pmid:20000402 |
| Morant M et al. | Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2. | 2010 | Mol Plant | pmid:20008451 |
| Truong VD et al. | Characterization of anthocyanins and anthocyanidins in purple-fleshed sweetpotatoes by HPLC-DAD/ESI-MS/MS. | 2010 | J. Agric. Food Chem. | pmid:20017481 |
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| Titta L et al. | Blood orange juice inhibits fat accumulation in mice. | 2010 | Int J Obes (Lond) | pmid:20029381 |
| Gargouri M et al. | The epimerase activity of anthocyanidin reductase from Vitis vinifera and its regiospecific hydride transfers. | Biol. Chem. | pmid:20030585 | |
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| Kim JE et al. | Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. | 2010 | Biochem. Pharmacol. | pmid:20096264 |
| Lee SJ et al. | Grape skin improves antioxidant capacity in rats fed a high fat diet. | 2009 | Nutr Res Pract | pmid:20098580 |
| Johnson ET et al. | Constitutive expression of the maize genes B1 and C1 in transgenic Hi II maize results in differential tissue pigmentation and generates resistance to Helicoverpa zea. | 2010 | J. Agric. Food Chem. | pmid:20108901 |
| Stushnoff C et al. | Flavonoid profiling and transcriptome analysis reveals new gene-metabolite correlations in tubers of Solanum tuberosum L. | 2010 | J. Exp. Bot. | pmid:20110266 |
| Yamagishi M et al. | Two R2R3-MYB genes, homologs of Petunia AN2, regulate anthocyanin biosyntheses in flower Tepals, tepal spots and leaves of asiatic hybrid lily. | 2010 | Plant Cell Physiol. | pmid:20118109 |
| Park MY et al. | Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin. | 2008 | Nutr Res Pract | pmid:20126360 |
| Kim MK et al. | Identification and quantification of anthocyanin pigments in colored rice. | 2008 | Nutr Res Pract | pmid:20126365 |
| Tarozzi A et al. | Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25-35) oligomer-induced toxicity. | 2010 | Neurosci. Lett. | pmid:20152881 |
| Lacombe A et al. | Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7. | 2010 | Int. J. Food Microbiol. | pmid:20153540 |
| Zikri NN et al. | Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. | 2009 | Nutr Cancer | pmid:20155622 |
| Tanaka T et al. | Chemistry of secondary polyphenols produced during processing of tea and selected foods. | 2009 | Int J Mol Sci | pmid:20161999 |
| Zhang Y et al. | Spectral alteration and degradation of cyanidin-3-glucoside exposed to pulsed electric field. | 2010 | J. Agric. Food Chem. | pmid:20163112 |
| Kim CY et al. | The sweet potato IbMYB1 gene as a potential visible marker for sweet potato intragenic vector system. | 2010 | Physiol Plant | pmid:20163556 |
| Rajani GP and Ashok P | In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. | 2009 | Indian J Pharmacol | pmid:20177495 |
| Deguchi Y and Miyazaki K | Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract. | 2010 | Nutr Metab (Lond) | pmid:20181067 |
| Choi JY et al. | Analysis and tentative structure elucidation of new anthocyanins in fruit peel of Vitis coignetiae Pulliat (meoru) using LC-MS/MS: Contribution to the overall antioxidant activity. | 2010 | J Sep Sci | pmid:20187032 |
| Felgines C et al. | Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse. | 2010 | Br. J. Nutr. | pmid:20187984 |
| Choi MJ et al. | Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system. | 2010 | Biol. Pharm. Bull. | pmid:20190403 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Delazar A et al. | Isolation and free-radical-scavenging properties of cyanidin 3-O-glycosides from the fruits of Ribes biebersteinii Berl. | 2010 | Acta Pharm | pmid:20228037 |
| Shi MZ and Xie DY | Features of anthocyanin biosynthesis in pap1-D and wild-type Arabidopsis thaliana plants grown in different light intensity and culture media conditions. | 2010 | Planta | pmid:20309578 |
| Zhang Y et al. | Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. | 2010 | Inflamm. Res. | pmid:20309718 |
| Han Y et al. | Ectopic expression of apple F3'H genes contributes to anthocyanin accumulation in the Arabidopsis tt7 mutant grown under nitrogen stress. | 2010 | Plant Physiol. | pmid:20357139 |
| Bae JY et al. | Protective actions of Rubus coreanus ethanol extract on collagenous extracellular matrix in ultraviolet-B irradiation-induced human dermal fibroblasts. | 2007 | Nutr Res Pract | pmid:20368951 |
| Halbwirth H | The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. | 2010 | Int J Mol Sci | pmid:20386656 |
| Wei S et al. | Concentration of rutin model solutions from their mixtures with glucose using ultrafiltration. | 2010 | Int J Mol Sci | pmid:20386660 |
| Li Z et al. | Effects of exogenous abscisic acid on yield, antioxidant capacities, and phytochemical contents of greenhouse grown lettuces. | 2010 | J. Agric. Food Chem. | pmid:20420437 |
| Suttana W et al. | Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. | 2010 | Mol. Cancer | pmid:20438634 |
| Solomon A et al. | Protection of fibroblasts (NIH-3T3) against oxidative damage by cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). | 2010 | J. Agric. Food Chem. | pmid:20443626 |
| Kuehl KS et al. | Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial. | 2010 | J Int Soc Sports Nutr | pmid:20459662 |
| Treutter D | Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. | 2010 | Int J Mol Sci | pmid:20479987 |
| D'Archivio M et al. | Bioavailability of the polyphenols: status and controversies. | 2010 | Int J Mol Sci | pmid:20480022 |