Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Choi MJ et al. | Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system. | 2010 | Biol. Pharm. Bull. | pmid:20190403 |
| Kim JE et al. | Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. | 2010 | Biochem. Pharmacol. | pmid:20096264 |
| Josuttis M et al. | Solar UVB response of bioactives in strawberry (Fragaria × ananassa Duch. L.): a comparison of protected and open-field cultivation. | 2010 | J. Agric. Food Chem. | pmid:21086998 |
| Li X et al. | Purple canola: Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. | 2010 | J. Agric. Food Chem. | pmid:20073469 |
| Treutter D | Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. | 2010 | Int J Mol Sci | pmid:20479987 |
| Qaâdan F et al. | Polyphenols from Ginkgo biloba. | 2010 Oct-Dec | Sci Pharm | pmid:21179324 |
| Lee J et al. | Natural products and body weight control. | 2011 | N Am J Med Sci | pmid:22540057 |
| Montefiori M et al. | Identification and characterisation of F3GT1 and F3GGT1, two glycosyltransferases responsible for anthocyanin biosynthesis in red-fleshed kiwifruit (Actinidia chinensis). | 2011 | Plant J. | pmid:21175894 |
| Khandelwal VK et al. | Hemidesmus indicus and Hibiscus rosa-sinensis Affect Ischemia Reperfusion Injury in Isolated Rat Hearts. | 2011 | Evid Based Complement Alternat Med | pmid:20953394 |
| Jing Yu V et al. | Identification of components of grape powder with anti-apoptotic effects. | 2011 | Toxicol Ind Health | pmid:20699283 |
| Biegelmeyer R et al. | Comparative analysis of the chemical composition and antioxidant activity of red (Psidium cattleianum) and yellow (Psidium cattleianum var. lucidum) strawberry guava fruit. | 2011 | J. Food Sci. | pmid:22417549 |
| Min J et al. | Neuroprotective effect of cyanidin-3-O-glucoside anthocyanin in mice with focal cerebral ischemia. | 2011 | Neurosci. Lett. | pmid:21651957 |
| Ben-Simhon Z et al. | A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development. | 2011 | Planta | pmid:21643990 |
| Cuevas Montilla E et al. | Soluble and bound phenolic compounds in different Bolivian purple corn ( Zea mays L.) cultivars. | 2011 | J. Agric. Food Chem. | pmid:21639140 |
| Jordheim M et al. | Identification of cyanidin 3-O-β-(6″-(3-hydroxy-3-methylglutaroyl)glucoside) and other anthocyanins from wild and cultivated blackberries. | 2011 | J. Agric. Food Chem. | pmid:21635009 |
| Esselen M et al. | Anthocyanin-rich blackberry extract suppresses the DNA-damaging properties of topoisomerase I and II poisons in colon carcinoma cells. | 2011 | J. Agric. Food Chem. | pmid:21599019 |
| Ju JH et al. | Anti-obesity and antioxidative effects of purple sweet potato extract in 3T3-L1 adipocytes in vitro. | 2011 | J Med Food | pmid:21861722 |
| Wang D et al. | Cyanidin-3-O-β-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein E-deficient mice. | 2011 | Biochem. Pharmacol. | pmid:21569764 |
| Xue YL et al. | Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki. | 2011 | J. Agric. Food Chem. | pmid:21568325 |
| Jin Y et al. | A randomised trial to investigate the effects of acute consumption of a blackcurrant juice drink on markers of vascular reactivity and bioavailability of anthocyanins in human subjects. | 2011 | Eur J Clin Nutr | pmid:21540876 |
| El Babili F et al. | Oregano: chemical analysis and evaluation of its antimalarial, antioxidant, and cytotoxic activities. | 2011 | J. Food Sci. | pmid:21535822 |
| Santos J et al. | Inhibition of host- and bacteria-derived proteinases by natural anthocyanins. | 2011 | J. Periodont. Res. | pmid:21517858 |
| Agati G et al. | The biosynthesis of flavonoids is enhanced similarly by UV radiation and root zone salinity in L. vulgare leaves. | 2011 | J. Plant Physiol. | pmid:20850892 |
| Mewis I et al. | Specific poly-phenolic compounds in cell culture of Vitis vinifera L. cv. Gamay Fréaux. | 2011 | Appl. Biochem. Biotechnol. | pmid:21061087 |
| Liu Y et al. | Comparative study of phenolic compounds and antioxidant activity in different species of cherries. | 2011 | J. Food Sci. | pmid:22417346 |
| Andrade JM et al. | Phenolic composition in different genotypes of Guabiju fruits (Myrcianthes pungens) and their potential as antioxidant and antichemotactic agents. | 2011 | J. Food Sci. | pmid:22417582 |
| Moze S et al. | Phenolics in Slovenian bilberries ( Vaccinium myrtillus L.) and blueberries ( Vaccinium corymbosum L.). | 2011 | J. Agric. Food Chem. | pmid:21574578 |
| Kyselova Z | Toxicological aspects of the use of phenolic compounds in disease prevention. | 2011 | Interdiscip Toxicol | pmid:22319251 |
| Kumar D et al. | A review on chemical and biological properties of Cayratia trifolia Linn. (Vitaceae). | 2011 | Pharmacogn Rev | pmid:22279376 |
| Fujimura Y et al. | Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars. | 2011 | PLoS ONE | pmid:21853132 |
| Mazzio EA et al. | The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | 2011 | Int J Mol Sci | pmid:21340000 |
| Kovinich N et al. | Combined analysis of transcriptome and metabolite data reveals extensive differences between black and brown nearly-isogenic soybean (Glycine max) seed coats enabling the identification of pigment isogenes. | 2011 | BMC Genomics | pmid:21801362 |
| Rawat S et al. | Assessment of Antioxidant Properties in Fruits of Myrica esculenta: A Popular Wild Edible Species in Indian Himalayan Region. | 2011 | Evid Based Complement Alternat Med | pmid:21785629 |
| Adisakwattana S et al. | Cyanidin-3-rutinoside alleviates postprandial hyperglycemia and its synergism with acarbose by inhibition of intestinal α-glucosidase. | 2011 | J Clin Biochem Nutr | pmid:21765605 |
| Shimazaki M et al. | Pink-colored grape berry is the result of short insertion in intron of color regulatory gene. | 2011 | PLoS ONE | pmid:21695059 |
| Liang Z et al. | CIELAB coordinates in response to berry skin anthocyanins and their composition in Vitis. | 2011 | J. Food Sci. | pmid:21535819 |
| Venkatesha SH et al. | Immunomodulation of Autoimmune Arthritis by Herbal CAM. | 2011 | Evid Based Complement Alternat Med | pmid:21234398 |
| Jakesevic M et al. | Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion. | 2011 | BMC Complement Altern Med | pmid:21272305 |
| Ali MB et al. | Berry skin development in Norton grape: distinct patterns of transcriptional regulation and flavonoid biosynthesis. | 2011 | BMC Plant Biol. | pmid:21219654 |
| Bhuiyan MI et al. | The Neuroprotective Potential of Cyanidin-3-glucoside Fraction Extracted from Mulberry Following Oxygen-glucose Deprivation. | 2011 | Korean J. Physiol. Pharmacol. | pmid:22359473 |
| Devi PS et al. | Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7). | 2011 | Int J Breast Cancer | pmid:22312562 |
| Korać RR and Khambholja KM | Potential of herbs in skin protection from ultraviolet radiation. | 2011 | Pharmacogn Rev | pmid:22279374 |
| Lin LZ et al. | UHPLC-PDA-ESI/HRMS/MS(n) analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard greens (Brassica juncea Coss variety). | 2011 | J. Agric. Food Chem. | pmid:21970730 |
| Ben Mansour H et al. | Correlation between antibutyrylcholinesterasic and antioxidant activities of three aqueous extracts from Tunisian Rhus pentaphyllum. | 2011 | Ann. Clin. Microbiol. Antimicrob. | pmid:21880140 |
| Clark ST and Verwoerd WS | A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants. | 2011 | BMC Bioinformatics | pmid:21849042 |
| He Q et al. | Natural variation in petal color in Lycoris longituba revealed by anthocyanin components. | 2011 | PLoS ONE | pmid:21829604 |
| Scazzocchio B et al. | Cyanidin-3-O-β-glucoside and protocatechuic acid exert insulin-like effects by upregulating PPARγ activity in human omental adipocytes. | 2011 | Diabetes | pmid:21788573 |
| Marin-Kuan M et al. | Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a. | 2011 | J Toxicol | pmid:21776264 |
| Ohno S et al. | A bHLH transcription factor, DvIVS, is involved in regulation of anthocyanin synthesis in dahlia (Dahlia variabilis). | 2011 | J. Exp. Bot. | pmid:21765172 |
| Kim CK et al. | Identification and characterization of seed-specific transcription factors regulating anthocyanin biosynthesis in black rice. | 2011 | J. Appl. Genet. | pmid:21286901 |