Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Felgines C et al. | Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse. | 2010 | Br. J. Nutr. | pmid:20187984 |
| Di Giacomo C et al. | Protective effect of cyanidin 3-O-beta-D-glucoside on ochratoxin A-mediated damage in the rat. | 2007 | Br. J. Nutr. | pmid:17562227 |
| Felgines C et al. | Strawberry pelargonidin glycosides are excreted in urine as intact glycosides and glucuronidated pelargonidin derivatives in rats. | 2007 | Br. J. Nutr. | pmid:17559698 |
| Felgines C et al. | Absorption and metabolism of red orange juice anthocyanins in rats. | 2006 | Br. J. Nutr. | pmid:16611379 |
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| Xu ZS et al. | Transcript profiling of structural genes involved in cyanidin-based anthocyanin biosynthesis between purple and non-purple carrot (Daucus carota L.) cultivars reveals distinct patterns. | 2014 | BMC Plant Biol. | pmid:25269413 |
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| Deluc LG et al. | Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay. | 2009 | BMC Genomics | pmid:19426499 |
| Jakesevic M et al. | Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion. | 2011 | BMC Complement Altern Med | pmid:21272305 |
| Ogawa K et al. | Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro. | 2014 | BMC Complement Altern Med | pmid:24690313 |
| Clark ST and Verwoerd WS | A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants. | 2011 | BMC Bioinformatics | pmid:21849042 |
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| Conn S et al. | Anthocyanic vacuolar inclusions (AVIs) selectively bind acylated anthocyanins in Vitis vinifera L. (grapevine) suspension culture. | 2003 | Biotechnol. Lett. | pmid:12889790 |
| Yan Y et al. | High-yield anthocyanin biosynthesis in engineered Escherichia coli. | 2008 | Biotechnol. Bioeng. | pmid:18023053 |
| Devi PS et al. | DNA Damage Protecting Activity and Free Radical Scavenging Activity of Anthocyanins from Red Sorghum (Sorghum bicolor) Bran. | 2012 | Biotechnol Res Int | pmid:22400119 |
| Islam MS et al. | Anthocyanin compositions in sweetpotato (Ipomoea batatas L.) leaves. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506993 |
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| Ueda H et al. | A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. | 2004 | Biosci. Biotechnol. Biochem. | pmid:14745173 |
| Moriya C et al. | New acylated anthocyanins from purple yam and their antioxidant activity. | 2015 | Biosci. Biotechnol. Biochem. | pmid:25848974 |
| Zhang G et al. | Structure-dependent photodegradation of carotenoids accelerated by dimethyl tetrasulfide under UVA irradiation. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685214 |
| Li JB et al. | Anthocyanins from red flowers of Camellia reticulata LINDL. | 2007 | Biosci. Biotechnol. Biochem. | pmid:18037731 |
| Watanabe M | An anthocyanin compound in buckwheat sprouts and its contribution to antioxidant capacity. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17284830 |
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| Jia Y et al. | Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23769638 |
| Turnbull JJ et al. | The C-4 stereochemistry of leucocyanidin substrates for anthocyanidin synthase affects product selectivity. | 2003 | Bioorg. Med. Chem. Lett. | pmid:14552794 |
| Takasawa R et al. | Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. | 2010 | Bioorg. Med. Chem. | pmid:20801663 |
| Kuhn I et al. | Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. | 2010 | Bioorg. Med. Chem. | pmid:20951593 |