Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fossen T et al. | Anthocyanins from maize (Zea mays) and reed canarygrass (Phalaris arundinacea). | 2001 | J. Agric. Food Chem. | pmid:11368596 |
| Matsui T et al. | alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins. | 2001 | J. Agric. Food Chem. | pmid:11308352 |
| Hyun JW and Chung HS | Cyanidin and Malvidin from Oryza sativa cv. Heugjinjubyeo mediate cytotoxicity against human monocytic leukemia cells by arrest of G(2)/M phase and induction of apoptosis. | 2004 | J. Agric. Food Chem. | pmid:15080622 |
| Oliveira Lde S et al. | Antioxidant metabolism during fruit development of different acerola (Malpighia emarginata D.C) clones. | 2012 | J. Agric. Food Chem. | pmid:22834960 |
| Park WT et al. | Metabolic profiling of glucosinolates, anthocyanins, carotenoids, and other secondary metabolites in kohlrabi (Brassica oleracea var. gongylodes). | 2012 | J. Agric. Food Chem. | pmid:22742768 |
| Iliopoulou I et al. | Analysis of the Thermal Degradation of the Individual Anthocyanin Compounds of Black Carrot (Daucus carota L.): A New Approach Using High-Resolution Proton Nuclear Magnetic Resonance Spectroscopy. | 2015 | J. Agric. Food Chem. | pmid:26160425 |
| Wiczkowski W et al. | Bioavailability of cyanidin glycosides from natural chokeberry (Aronia melanocarpa) juice with dietary-relevant dose of anthocyanins in humans. | 2010 | J. Agric. Food Chem. | pmid:21067240 |
| Montilla EC et al. | Anthocyanin composition of black carrot (Daucus carota ssp. sativus var. atrorubens Alef.) cultivars Antonina, Beta Sweet, Deep Purple, and Purple Haze. | 2011 | J. Agric. Food Chem. | pmid:21381748 |
| Zhang Y et al. | Spectral alteration and degradation of cyanidin-3-glucoside exposed to pulsed electric field. | 2010 | J. Agric. Food Chem. | pmid:20163112 |
| Asada T and Tamura H | Isolation of bilberry anthocyanidin 3-glycosides bearing ortho-dihydroxyl groups on the B ring by forming an aluminum complex and their antioxidant activity. | 2012 | J. Agric. Food Chem. | pmid:23025407 |
| Shih PH et al. | Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways. | 2012 | J. Agric. Food Chem. | pmid:22364184 |
| Stalmach A et al. | Identification of (poly)phenolic compounds in concord grape juice and their metabolites in human plasma and urine after juice consumption. | 2011 | J. Agric. Food Chem. | pmid:21812481 |
| Xu C et al. | Influence of growing season on phenolic compounds and antioxidant properties of grape berries from vines grown in subtropical climate. | 2011 | J. Agric. Food Chem. | pmid:21235208 |
| Meiers S et al. | The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. | 2001 | J. Agric. Food Chem. | pmid:11262056 |
| Vasco C et al. | Phenolic compounds in Rosaceae fruits from Ecuador. | 2009 | J. Agric. Food Chem. | pmid:19143537 |
| You Q et al. | Inhibitory effects of muscadine anthocyanins on α-glucosidase and pancreatic lipase activities. | 2011 | J. Agric. Food Chem. | pmid:21797278 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
| Kähkönen MP and Heinonen M | Antioxidant activity of anthocyanins and their aglycons. | 2003 | J. Agric. Food Chem. | pmid:12537433 |
| Montefiori M et al. | Characterization and quantification of anthocyanins in red kiwifruit ( Actinidia spp.). | 2009 | J. Agric. Food Chem. | pmid:19572542 |
| Pawlowska AM et al. | Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits. | 2008 | J. Agric. Food Chem. | pmid:18412362 |
| Bellido GG and Beta T | Anthocyanin composition and oxygen radical scavenging capacity (ORAC) of milled and pearled purple, black, and common barley. | 2009 | J. Agric. Food Chem. | pmid:19159302 |
| Tulio AZ et al. | Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry. | 2008 | J. Agric. Food Chem. | pmid:18290621 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Aaby K et al. | Characterization of phenolic compounds in strawberry (Fragaria x ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity. | 2007 | J. Agric. Food Chem. | pmid:17472391 |
| Iwai K et al. | Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb. | 2006 | J. Agric. Food Chem. | pmid:16787002 |
| Meng L et al. | Anthocyanin and flavonoid production from Perilla frutescens: pilot plant scale processing including cross-flow microfiltration and reverse osmosis. | 2006 | J. Agric. Food Chem. | pmid:16756359 |
| Srivastava A et al. | Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and phase II enzymes. | 2007 | J. Agric. Food Chem. | pmid:17381106 |
| Ichiyanagi T et al. | Extended glucuronidation is another major path of cyanidin 3-O-beta-D-glucopyranoside metabolism in rats. | 2005 | J. Agric. Food Chem. | pmid:16131148 |
| Tian Q et al. | Probing anthocyanin profiles in purple sweet potato cell line (Ipomoea batatas L. Cv. Ayamurasaki) by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry. | 2005 | J. Agric. Food Chem. | pmid:16076141 |
| Espinosa-Alonso LG et al. | Polyphenols in wild and weedy Mexican common beans (Phaseolus vulgaris L.). | 2006 | J. Agric. Food Chem. | pmid:16756378 |
| Innocenti M et al. | Evaluation of the phenolic content in the aerial parts of different varieties of Cichorium intybus L. | 2005 | J. Agric. Food Chem. | pmid:16076140 |
| Wu X et al. | Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption. | 2006 | J. Agric. Food Chem. | pmid:16719536 |
| Kayodé AP et al. | Uncommonly high levels of 3-deoxyanthocyanidins and antioxidant capacity in the leaf sheaths of dye sorghum. | 2011 | J. Agric. Food Chem. | pmid:21322653 |
| Lee J et al. | Comparison of anthocyanin pigment and other phenolic compounds of Vaccinium membranaceum and Vaccinium ovatum native to the Pacific Northwest of North America. | 2004 | J. Agric. Food Chem. | pmid:15537315 |
| Chang Q and Wong YS | Identification of flavonoids in Hakmeitau beans (Vigna sinensis) by high-performance liquid chromatography-electrospray mass spectrometry (LC-ESI/MS). | 2004 | J. Agric. Food Chem. | pmid:15506802 |
| Muñoz-Espada AC et al. | Anthocyanin quantification and radical scavenging capacity of Concord, Norton, and Marechal Foch grapes and wines. | 2004 | J. Agric. Food Chem. | pmid:15506816 |
| Määttä-Riihinen KR et al. | Identification and quantification of phenolic compounds in berries of Fragaria and Rubus species (family Rosaceae). | 2004 | J. Agric. Food Chem. | pmid:15453684 |
| Choung MG et al. | Anthocyanin profile of Korean cultivated kidney bean (Phaseolus vulgaris L.). | 2003 | J. Agric. Food Chem. | pmid:14611168 |
| Chun OK et al. | Superoxide radical scavenging activity of the major polyphenols in fresh plums. | 2003 | J. Agric. Food Chem. | pmid:14690398 |
| Ella Missang C et al. | Flavonols and anthocyanins of bush butter, Dacryodes edulis (G. Don) H.J. Lam, fruit. changes in their composition during ripening. | 2003 | J. Agric. Food Chem. | pmid:14640602 |
| Määttä KR et al. | High-performance liquid chromatography (HPLC) analysis of phenolic compounds in berries with diode array and electrospray ionization mass spectrometric (MS) detection: ribes species. | 2003 | J. Agric. Food Chem. | pmid:14582969 |
| Terasawa N et al. | Identification and some properties of anthocyanin isolated from Zuiki, stalk of Colocasia esculenta. | 2007 | J. Agric. Food Chem. | pmid:17447784 |
| Matsumoto H et al. | Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. | 2001 | J. Agric. Food Chem. | pmid:11312894 |
| Matsumoto H et al. | Preparative-scale isolation of four anthocyanin components of black currant (Ribes nigrum L.) fruits. | 2001 | J. Agric. Food Chem. | pmid:11312893 |
| Wolfe KL and Liu RH | Apple peels as a value-added food ingredient. | 2003 | J. Agric. Food Chem. | pmid:12617604 |
| Wolfe K et al. | Antioxidant activity of apple peels. | 2003 | J. Agric. Food Chem. | pmid:12537430 |
| Zheng W and Wang SY | Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. | 2003 | J. Agric. Food Chem. | pmid:12517117 |
| Rajbhandari R et al. | Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. | 2011 | J. Agric. Food Chem. | pmid:21634376 |
| Yang H et al. | Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. | 2011 | J. Agric. Food Chem. | pmid:21302942 |
| Chandra A et al. | Separation, identification, quantification, and method validation of anthocyanins in botanical supplement raw materials by HPLC and HPLC-MS. | 2001 | J. Agric. Food Chem. | pmid:11513621 |