Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gras CC et al. | Effect of chlorogenic acid on spectral properties and stability of acylated and non-acylated cyanidin-3-O-glycosides. | 2018 | Food Chem | pmid:28946365 |
| Ieri F et al. | Simultaneous determination of anthocyanins, coumarins and phenolic acids in fruits, kernels and liqueur of Prunus mahaleb L. | 2012 | Food Chem | pmid:22980784 |
| Ahmadiani N et al. | Molar absorptivity (ε) and spectral characteristics of cyanidin-based anthocyanins from red cabbage. | 2016 | Food Chem | pmid:26617032 |
| Lima Mdos S et al. | Phenolic compounds, organic acids and antioxidant activity of grape juices produced in industrial scale by different processes of maceration. | 2015 | Food Chem | pmid:26041208 |
| Park S et al. | Quantification of glucosinolates, anthocyanins, free amino acids, and vitamin C in inbred lines of cabbage (Brassica oleracea L.). | 2014 | Food Chem | pmid:24128451 |
| Takahama U et al. | Isolation and characterization of a cyanidin-catechin pigment from adzuki bean (Vigna angularis). | 2013 | Food Chem | pmid:23768359 |
| Sui X and Zhou W | Monte Carlo modelling of non-isothermal degradation of two cyanidin-based anthocyanins in aqueous system at high temperatures and its impact on antioxidant capacities. | 2014 | Food Chem | pmid:24262567 |
| González-Barrio R et al. | Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds. | 2018 | Food Chem | pmid:29478556 |
| Dai J et al. | A comprehensive study of anthocyanin-containing extracts from selected blackberry cultivars: extraction methods, stability, anticancer properties and mechanisms. | 2009 | Food Chem. Toxicol. | pmid:19271318 |
| Cásedas G et al. | Regulation of redox status in neuronal SH-SY5Y cells by blueberry (Vaccinium myrtillus L.) juice, cranberry (Vaccinium macrocarpon A.) juice and cyanidin. | 2018 | Food Chem. Toxicol. | pmid:29860017 |
| Li F et al. | Cyanidin ameliorates endotoxin-induced myocardial toxicity by modulating inflammation and oxidative stress through mitochondria and other factors. | 2018 | Food Chem. Toxicol. | pmid:29803697 |
| Min K and Ebeler SE | Flavonoid effects on DNA oxidation at low concentrations relevant to physiological levels. | 2008 | Food Chem. Toxicol. | pmid:17707569 |
| Choi EH et al. | Cytoprotective effect of anthocyanins against doxorubicin-induced toxicity in H9c2 cardiomyocytes in relation to their antioxidant activities. | 2007 | Food Chem. Toxicol. | pmid:17524543 |
| Matsufuji H et al. | Formation and inhibition of genotoxic malonaldehyde from DNA oxidation controlled with EDTA. | 2006 | Food Chem. Toxicol. | pmid:16122862 |
| Shih PH et al. | Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. | 2005 | Food Chem. Toxicol. | pmid:15964118 |
| Riha J et al. | Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes. | 2015 | Food Funct | pmid:25578040 |
| Fernandes I et al. | A new approach on the gastric absorption of anthocyanins. | 2012 | Food Funct | pmid:22391951 |
| Raj P et al. | Effects of cyanidin 3-0-glucoside on cardiac structure and function in an animal model of myocardial infarction. | 2017 | Food Funct | pmid:28990610 |
| Zhang J et al. | The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus. | 2004 | Free Radic. Biol. Med. | pmid:15336320 |
| Ziberna L et al. | Transport and bioactivity of cyanidin 3-glucoside into the vascular endothelium. | 2012 | Free Radic. Biol. Med. | pmid:22387282 |