Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamaura K et al. | Anthocyanins from bilberry (Vaccinium myrtillus L.) alleviate pruritus in a mouse model of chronic allergic contact dermatitis. | 2011 | Pharmacognosy Res | pmid:22022165 |
| Ernst IM et al. | Cellular uptake, stability, visualization by 'Naturstoff reagent A', and multidrug resistance protein 1 gene-regulatory activity of cyanidin in human keratinocytes. | 2010 | Pharmacol. Res. | pmid:19897037 |
| Dreiseitel A et al. | Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B. | 2009 | Pharmacol. Res. | pmid:19416630 |
| Chen J et al. | Cyanidin Protects SH-SY5Y Human Neuroblastoma Cells from 1-Methyl-4-Phenylpyridinium-Induced Neurotoxicity. | 2018 | Pharmacology | pmid:29982258 |
| Tirupula KC et al. | pH-dependent interaction of rhodopsin with cyanidin-3-glucoside. 2. Functional aspects. | Photochem. Photobiol. | pmid:19267871 | |
| Yanamala N et al. | pH-dependent interaction of rhodopsin with cyanidin-3-glucoside. 1. Structural aspects. | Photochem. Photobiol. | pmid:19192199 | |
| Afaq F et al. | Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign. | Photochem. Photobiol. | pmid:15493960 | |
| Jang YP et al. | Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells. | 2005 May-Jun | Photochem. Photobiol. | pmid:15745429 |
| Chu H et al. | Expression of the sweetpotato R2R3-type IbMYB1a gene induces anthocyanin accumulation in Arabidopsis. | 2013 | Physiol Plant | pmid:23039825 |
| Kim CY et al. | The sweet potato IbMYB1 gene as a potential visible marker for sweet potato intragenic vector system. | 2010 | Physiol Plant | pmid:20163556 |
| Escribano-Bailón MT et al. | Anthocyanin composition of the fruit of Coriaria myrtifolia L. | 2002 Nov-Dec | Phytochem Anal | pmid:12494755 |
| Asenstorfer RE et al. | Purification of anthocyanins from species of Banksia and Acacia using high-voltage paper electrophoresis. | Phytochem Anal | pmid:12793461 | |
| Romani A et al. | Identification and quantification of galloyl derivatives, flavonoid glycosides and anthocyanins in leaves of Pistacia lentiscus L. | Phytochem Anal | pmid:12018027 | |
| Bjorøy O et al. | C-glycosylanthocyanidins synthesized from C-glycosylflavones. | 2009 | Phytochemistry | pmid:19185884 |
| Saito N et al. | Covalent anthocyanin-flavonol complexes from the violet-blue flowers of Allium 'Blue Perfume'. | 2012 | Phytochemistry | pmid:22704652 |
| Hall D et al. | Molecular cloning and biochemical characterization of the UDP-glucose: flavonoid 3-O-glucosyltransferase from Concord grape (Vitis labrusca). | 2012 | Phytochemistry | pmid:22098678 |
| Tatsuzawa F et al. | Triacylated cyanidin 3-(3X-glucosylsambubioside)-5-glucosides from the flowers of Malcolmia maritima. | 2008 | Phytochemistry | pmid:17928016 |
| Pale E et al. | Two triacylated and tetraglucosylated anthocyanins from Ipomoea asarifolia flowers. | 2003 | Phytochemistry | pmid:14630005 |
| Salvatierra A et al. | Comparison of transcriptional profiles of flavonoid genes and anthocyanin contents during fruit development of two botanical forms of Fragaria chiloensis ssp. chiloensis. | 2010 | Phytochemistry | pmid:20800857 |
| Honda T et al. | Acylated anthocyanins from the violet-blue flowers of Orychophragonus violaceus. | 2005 | Phytochemistry | pmid:16023157 |
| Andersen ØM et al. | Anthocyanins with unusual furanose sugar (apiose) from leaves of Synadenium grantii (Euphorbiaceae). | 2010 | Phytochemistry | pmid:20594565 |
| Saito N et al. | Tetra-acylated cyanidin 3-sophoroside-5-glucosides from the flowers of Iberis umbellata L. (Cruciferae). | 2008 | Phytochemistry | pmid:18514755 |
| Tatsuzawa F et al. | Triacylated peonidin 3-sophoroside-5-glucosides from the purple flowers of Moricandia ramburii Webb. | 2012 | Phytochemistry | pmid:22264647 |
| Owens DK and McIntosh CA | Identification, recombinant expression, and biochemical characterization of a flavonol 3-O-glucosyltransferase clone from Citrus paradisi. | Phytochemistry | pmid:19733370 | |
| Saito N et al. | The blue anthocyanin pigments from the blue flowers of Heliophila coronopifolia L. (Brassicaceae). | 2011 | Phytochemistry | pmid:21903230 |
| Nakabayashi R et al. | Metabolomics-oriented isolation and structure elucidation of 37 compounds including two anthocyanins from Arabidopsis thaliana. | 2009 | Phytochemistry | pmid:19497599 |
| Lätti AK et al. | Phenolic compounds in berries and flowers of a natural hybrid between bilberry and lingonberry (Vaccinium × intermedium Ruthe). | 2011 | Phytochemistry | pmid:21382629 |
| Li JB et al. | Anthocyanins from red flowers of Camellia cultivar 'Dalicha'. | 2008 | Phytochemistry | pmid:18466934 |
| Sakaguchi Y et al. | Major anthocyanins from purple asparagus (Asparagus officinalis). | 2008 | Phytochemistry | pmid:18406435 |
| Tatsuzawa F et al. | 6-Hydroxypelargonidin glycosides in the orange-red flowers of Alstroemeria. | 2003 | Phytochemistry | pmid:12648544 |
| Kovinich N et al. | Functional characterization of a UDP-glucose:flavonoid 3-O-glucosyltransferase from the seed coat of black soybean (Glycine max (L.) Merr.). | 2010 | Phytochemistry | pmid:20621794 |
| Tatsuzawa F et al. | Acylated cyanidin 3-sambubioside-5-glucosides in three garden plants of the Cruciferae. | 2006 | Phytochemistry | pmid:16777160 |
| Yoshida K et al. | Ferric ions involved in the flower color development of the Himalayan blue poppy, Meconopsis grandis. | 2006 | Phytochemistry | pmid:16678868 |
| Saito N et al. | Acylated anthocyanins from the blue-violet flowers of Anemone coronaria. | 2002 | Phytochemistry | pmid:12031427 |
| Seitz C et al. | Redirection of anthocyanin synthesis in Osteospermum hybrida by a two-enzyme manipulation strategy. | 2007 | Phytochemistry | pmid:17286993 |
| Ando T et al. | Delphinidin accumulation is associated with abnormal flower development in petunias. | 2004 | Phytochemistry | pmid:15587706 |
| Takeda K et al. | Components of protocyanin, a blue pigment from the blue flowers of Centaurea cyanus. | 2005 | Phytochemistry | pmid:16005311 |
| McDougall GJ et al. | Anthocyanins from red wine--their stability under simulated gastrointestinal digestion. | 2005 | Phytochemistry | pmid:16242736 |
| Nimal Punyasiri PA et al. | Exobasidium vexans infection of Camellia sinensis increased 2,3-cis isomerisation and gallate esterification of proanthocyanidins. | 2004 | Phytochemistry | pmid:15504433 |
| Marles MA et al. | New perspectives on proanthocyanidin biochemistry and molecular regulation. | 2003 | Phytochemistry | pmid:12943753 |
| Fukui Y et al. | A rationale for the shift in colour towards blue in transgenic carnation flowers expressing the flavonoid 3',5'-hydroxylase gene. | 2003 | Phytochemistry | pmid:12657292 |
| Tanaka M et al. | A malonylated anthocyanin and flavonols in blue Meconopsis flowers. | 2001 | Phytochemistry | pmid:11249104 |
| Fossen T et al. | Anthocyanins with 4'-glucosidation from red onion, Allium cepa. | 2003 | Phytochemistry | pmid:14630001 |
| Nielsen AH et al. | Flavonoids in flowers of 16 Kalanchoë blossfeldiana varieties. | 2005 | Phytochemistry | pmid:16297414 |
| Reiersen B et al. | Anthocyanins acylated with gallic acid from chenille plant, Acalypha hispida. | 2003 | Phytochemistry | pmid:14559283 |
| Terahara N et al. | Acylated anthocyanidin 3-sophoroside-5-glucosides from Ajuga reptans flowers and the corresponding cell cultures. | 2001 | Phytochemistry | pmid:11557083 |
| Fossen T and Øvstedal DO | Anthocyanins from flowers of the orchids Dracula chimaera and D. cordobae. | 2003 | Phytochemistry | pmid:12877919 |
| Terahara N et al. | Anthocyanins from red flower tea (Benibana-cha), Camellia sinensis. | 2001 | Phytochemistry | pmid:11249101 |
| Goda Y et al. | Two acylated anthocyanins from purple sweet potato. | 1997 | Phytochemistry | pmid:8983218 |
| Bloor SJ and Abrahams S | The structure of the major anthocyanin in Arabidopsis thaliana. | 2002 | Phytochemistry | pmid:11830144 |