Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Wang H et al. | Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. | 1999 | J. Nat. Prod. | pmid:10075763 |
| Redus M et al. | Rate and equilibrium constants for the dehydration and deprotonation reactions of some monoacylated and glycosylated cyanidin derivatives. | 1999 | J. Agric. Food Chem. | pmid:10552670 |
| Terahara N et al. | Anthocyanins from red flower tea (Benibana-cha), Camellia sinensis. | 2001 | Phytochemistry | pmid:11249101 |
| Tanaka M et al. | A malonylated anthocyanin and flavonols in blue Meconopsis flowers. | 2001 | Phytochemistry | pmid:11249104 |
| Meiers S et al. | The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. | 2001 | J. Agric. Food Chem. | pmid:11262056 |
| Matsui T et al. | alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins. | 2001 | J. Agric. Food Chem. | pmid:11308352 |
| Matsumoto H et al. | Preparative-scale isolation of four anthocyanin components of black currant (Ribes nigrum L.) fruits. | 2001 | J. Agric. Food Chem. | pmid:11312893 |
| Matsumoto H et al. | Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. | 2001 | J. Agric. Food Chem. | pmid:11312894 |
| Nakajima J et al. | Reaction mechanism from leucoanthocyanidin to anthocyanidin 3-glucoside, a key reaction for coloring in anthocyanin biosynthesis. | 2001 | J. Biol. Chem. | pmid:11316805 |
| Fossen T et al. | Anthocyanins from maize (Zea mays) and reed canarygrass (Phalaris arundinacea). | 2001 | J. Agric. Food Chem. | pmid:11368596 |
| Chandra A et al. | Separation, identification, quantification, and method validation of anthocyanins in botanical supplement raw materials by HPLC and HPLC-MS. | 2001 | J. Agric. Food Chem. | pmid:11513621 |
| Terahara N et al. | Acylated anthocyanidin 3-sophoroside-5-glucosides from Ajuga reptans flowers and the corresponding cell cultures. | 2001 | Phytochemistry | pmid:11557083 |
| Nyman NA and Kumpulainen JT | Determination of anthocyanidins in berries and red wine by high-performance liquid chromatography. | 2001 | J. Agric. Food Chem. | pmid:11559107 |
| Seeram NP et al. | Degradation products of cyanidin glycosides from tart cherries and their bioactivities. | 2001 | J. Agric. Food Chem. | pmid:11600045 |
| Wang SY and Zheng W | Effect of plant growth temperature on antioxidant capacity in strawberry. | 2001 | J. Agric. Food Chem. | pmid:11600054 |
| Ramirez-Tortosa C et al. | Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats. | 2001 | Free Radic. Biol. Med. | pmid:11677035 |
| Seeram NP et al. | Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries. | 2001 | Phytomedicine | pmid:11695879 |
| Aharoni A et al. | The strawberry FaMYB1 transcription factor suppresses anthocyanin and flavonol accumulation in transgenic tobacco. | 2001 | Plant J. | pmid:11722774 |
| Noda Y et al. | Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. | 2002 | J. Agric. Food Chem. | pmid:11754562 |
| Stintzing FC et al. | A novel zwitterionic anthocyanin from evergreen blackberry (Rubus laciniatus Willd.). | 2002 | J. Agric. Food Chem. | pmid:11782214 |
| Wang J and Mazza G | Inhibitory effects of anthocyanins and other phenolic compounds on nitric oxide production in LPS/IFN-gamma-activated RAW 264.7 macrophages. | 2002 | J. Agric. Food Chem. | pmid:11829656 |
| Bloor SJ and Abrahams S | The structure of the major anthocyanin in Arabidopsis thaliana. | 2002 | Phytochemistry | pmid:11830144 |
| Vogt T | Substrate specificity and sequence analysis define a polyphyletic origin of betanidin 5- and 6-O-glucosyltransferase from Dorotheanthus bellidiformis. | 2002 | Planta | pmid:11855654 |
| Gennaro L et al. | Flavonoid and carbohydrate contents in Tropea red onions: effects of homelike peeling and storage. | 2002 | J. Agric. Food Chem. | pmid:11902931 |
| Seeram NP et al. | Characterization, quantification, and bioactivities of anthocyanins in Cornus species. | 2002 | J. Agric. Food Chem. | pmid:11958615 |
| Slimestad R and Solheim H | Anthocyanins from black currants (Ribes nigrum L.). | 2002 | J. Agric. Food Chem. | pmid:12009991 |
| Romani A et al. | Identification and quantification of galloyl derivatives, flavonoid glycosides and anthocyanins in leaves of Pistacia lentiscus L. | Phytochem Anal | pmid:12018027 | |
| Saito N et al. | Acylated anthocyanins from the blue-violet flowers of Anemone coronaria. | 2002 | Phytochemistry | pmid:12031427 |
| Milbury PE et al. | Bioavailablility of elderberry anthocyanins. | 2002 | Mech. Ageing Dev. | pmid:12044949 |
| Ross JA and Kasum CM | Dietary flavonoids: bioavailability, metabolic effects, and safety. | 2002 | Annu. Rev. Nutr. | pmid:12055336 |
| Briviba K et al. | Neurotensin-and EGF-induced metabolic activation of colon carcinoma cells is diminished by dietary flavonoid cyanidin but not by its glycosides. | 2001 | Nutr Cancer | pmid:12094622 |
| Page JE and Towers GH | Anthocyanins protect light-sensitive thiarubrine phototoxins. | 2002 | Planta | pmid:12111231 |
| Es-Safi NE et al. | Interactions between cyanidin 3-O-glucoside and furfural derivatives and their impact on food color changes. | 2002 | J. Agric. Food Chem. | pmid:12236682 |
| Cantos E et al. | Varietal differences among the polyphenol profiles of seven table grape cultivars studied by LC-DAD-MS-MS. | 2002 | J. Agric. Food Chem. | pmid:12236700 |
| Yan X et al. | Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon). | 2002 | J. Agric. Food Chem. | pmid:12358448 |
| Stintzing FC et al. | Color and antioxidant properties of cyanidin-based anthocyanin pigments. | 2002 | J. Agric. Food Chem. | pmid:12358498 |
| Wang SY et al. | Cultural system affects fruit quality and antioxidant capacity in strawberries. | 2002 | J. Agric. Food Chem. | pmid:12381146 |
| Frank J et al. | Effects of dietary anthocyanins on tocopherols and lipids in rats. | 2002 | J. Agric. Food Chem. | pmid:12452636 |
| Eiro MJ and Heinonen M | Anthocyanin color behavior and stability during storage: effect of intermolecular copigmentation. | 2002 | J. Agric. Food Chem. | pmid:12452676 |
| Rossetto M et al. | Synergistic antioxidant effect of catechin and malvidin 3-glucoside on free radical-initiated peroxidation of linoleic acid in micelles. | 2002 | Arch. Biochem. Biophys. | pmid:12464277 |
| Cervellati R et al. | Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. | 2002 | J. Agric. Food Chem. | pmid:12475261 |
| Suzuki H et al. | cDNA cloning, heterologous expressions, and functional characterization of malonyl-coenzyme a:anthocyanidin 3-o-glucoside-6"-o-malonyltransferase from dahlia flowers. | 2002 | Plant Physiol. | pmid:12481098 |
| Escribano-Bailón MT et al. | Anthocyanin composition of the fruit of Coriaria myrtifolia L. | 2002 Nov-Dec | Phytochem Anal | pmid:12494755 |
| Islam MS et al. | Anthocyanin compositions in sweetpotato (Ipomoea batatas L.) leaves. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506993 |
| Zheng W and Wang SY | Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. | 2003 | J. Agric. Food Chem. | pmid:12517117 |
| Wolfe K et al. | Antioxidant activity of apple peels. | 2003 | J. Agric. Food Chem. | pmid:12537430 |
| Kähkönen MP and Heinonen M | Antioxidant activity of anthocyanins and their aglycons. | 2003 | J. Agric. Food Chem. | pmid:12537433 |
| Lazzé MC et al. | Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells. | 2003 | Mutat. Res. | pmid:12547288 |
| Katsuzaki H et al. | Cyanidin 3-O-beta-D-glucoside isolated from skin of black Glycine max and other anthocyanins isolated from skin of red grape induce apoptosis in human lymphoid leukemia Molt 4B cells. | Oncol. Rep. | pmid:12579261 |