Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jang HH et al. | In vitro and in vivo hypoglycemic effects of cyanidin 3-caffeoyl-p-hydroxybenzoylsophoroside-5-glucoside, an anthocyanin isolated from purple-fleshed sweet potato. | 2019 | Food Chem | pmid:30309599 |
| Gras CC et al. | Effect of chlorogenic acid on spectral properties and stability of acylated and non-acylated cyanidin-3-O-glycosides. | 2018 | Food Chem | pmid:28946365 |
| Cheng J et al. | Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways. | 2018 | J. Cell. Physiol. | pmid:28771720 |
| Cao Z et al. | Cyanidin suppresses autophagic activity regulating chondrocyte hypertrophic differentiation. | 2018 | J. Cell. Physiol. | pmid:28722162 |
| Daveri E et al. | Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice. | 2018 | Redox Biol | pmid:29890336 |
| Zykin PA et al. | Anthocyanin Composition and Content in Rye Plants with Different Grain Color. | 2018 | Molecules | pmid:29671758 |
| González-Barrio R et al. | Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds. | 2018 | Food Chem | pmid:29478556 |
| Henarejos-Escudero P et al. | Digestive glands extraction and precise pigment analysis support the exclusion of the carnivorous plant Dionaea muscipula Ellis from the Caryophyllales order. | 2018 | Plant Sci. | pmid:30080622 |
| Chen J et al. | Cyanidin Protects SH-SY5Y Human Neuroblastoma Cells from 1-Methyl-4-Phenylpyridinium-Induced Neurotoxicity. | 2018 | Pharmacology | pmid:29982258 |
| Cásedas G et al. | Regulation of redox status in neuronal SH-SY5Y cells by blueberry (Vaccinium myrtillus L.) juice, cranberry (Vaccinium macrocarpon A.) juice and cyanidin. | 2018 | Food Chem. Toxicol. | pmid:29860017 |
| Li F et al. | Cyanidin ameliorates endotoxin-induced myocardial toxicity by modulating inflammation and oxidative stress through mitochondria and other factors. | 2018 | Food Chem. Toxicol. | pmid:29803697 |
| Liu X et al. | Cyanidin Curtails Renal Cell Carcinoma Tumorigenesis. | 2018 | Cell. Physiol. Biochem. | pmid:29742507 |
| Farr JE et al. | Influence of cyanidin glycosylation patterns on carboxypyranoanthocyanin formation. | 2018 | Food Chem | pmid:29680053 |
| Feng K et al. | Isolation, purification, and characterization of AgUCGalT1, a galactosyltransferase involved in anthocyanin galactosylation in purple celery (Apium graveolens L.). | 2018 | Planta | pmid:29520459 |
| Poobathy R et al. | Autofluorescence study and selected cyanidin quantification in the Jewel orchids Anoectochilus sp. and Ludisia discolor. | 2018 | PLoS ONE | pmid:29649288 |
| Du H et al. | Characterisation of flower colouration in 30 Rhododendron species via anthocyanin and flavonol identification and quantitative traits. | 2018 | Plant Biol (Stuttg) | pmid:29054107 |
| Cyboran-Mikołajczyk S et al. | The Impact of O-Glycosylation on Cyanidin Interaction with POPC Membranes: Structure-Activity Relationship. | 2018 | Molecules | pmid:30366469 |
| Aybastıer Ö et al. | Investigation of antioxidant ability of grape seeds extract to prevent oxidatively induced DNA damage by gas chromatography-tandem mass spectrometry. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29223045 |
| Yari A and Rashnoo S | Optimization of a new method for extraction of cyanidin chloride and pelargonidin chloride anthocyanins with magnetic solid phase extraction and determination in fruit samples by HPLC with central composite design. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28987497 |
| Boehm MMA et al. | Dissecting the 'bacon and eggs' phenotype: transcriptomics of post-anthesis colour change in Lotus. | 2017 | Ann. Bot. | pmid:28981620 |
| Bashandy H and Teeri TH | Genetically engineered orange petunias on the market. | 2017 | Planta | pmid:28647812 |
| Petruk G et al. | Malvidin and cyanidin derivatives from açai fruit (Euterpe oleracea Mart.) counteract UV-A-induced oxidative stress in immortalized fibroblasts. | 2017 | J. Photochem. Photobiol. B, Biol. | pmid:28527426 |
| Sgherri C et al. | Elevated CO and salinity are responsible for phenolics-enrichment in two differently pigmented lettuces. | 2017 | Plant Physiol. Biochem. | pmid:28411511 |
| Hemachandran H et al. | Unraveling the inhibition mechanism of cyanidin-3-sophoroside on polyphenol oxidase and its effect on enzymatic browning of apples. | 2017 | Food Chem | pmid:28274409 |
| Fedenko VS et al. | UV-vis spectroscopy and colorimetric models for detecting anthocyanin-metal complexes in plants: An overview of in vitro and in vivo techniques. | 2017 | J. Plant Physiol. | pmid:28242414 |
| Liu C et al. | The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo. | 2017 | Sci Signal | pmid:28223414 |
| McCarthy EW et al. | Related allopolyploids display distinct floral pigment profiles and transgressive pigments. | 2017 | Am. J. Bot. | pmid:28057690 |
| Sigurdson GT et al. | Spectral and colorimetric characteristics of metal chelates of acylated cyanidin derivatives. | 2017 | Food Chem | pmid:27979063 |
| Kimura Y et al. | Synthesis of 8-Aryl-O-methylcyanidins and Their Usage for Dye-Sensitized Solar Cell Devices. | 2017 | Int J Mol Sci | pmid:28212330 |
| Raj P et al. | Effects of cyanidin 3-0-glucoside on cardiac structure and function in an animal model of myocardial infarction. | 2017 | Food Funct | pmid:28990610 |
| Suantawee T et al. | Cyanidin Stimulates Insulin Secretion and Pancreatic β-Cell Gene Expression through Activation of l-type Voltage-Dependent Ca Channels. | 2017 | Nutrients | pmid:28788070 |
| Xu Z et al. | ROS Induces Anthocyanin Production Via Late Biosynthetic Genes and Anthocyanin Deficiency Confers the Hypersensitivity to ROS-Generating Stresses in Arabidopsis. | 2017 | Plant Cell Physiol. | pmid:28586465 |
| Batista ÂG et al. | Jaboticaba berry peel intake prevents insulin-resistance-induced tau phosphorylation in mice. | 2017 | Mol Nutr Food Res | pmid:28544198 |
| Lagoa R et al. | Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin-induced peroxidase activity. | 2017 | Biofactors | pmid:28317253 |
| Liu YY et al. | [Establishment of myocardial targeted nanoparticles and preliminary evaluation of its effects on prevention and treatment of myocardial injury]. | 2017 | Zhonghua Shao Shang Za Zhi | pmid:29166707 |
| Carvalho MJ et al. | Nutritional and Phytochemical Composition of Vaccinium padifolium Sm Wild Berries and Radical Scavenging Activity. | 2017 | J. Food Sci. | pmid:28960302 |
| Suantawee T et al. | Protective effect of cyanidin against glucose- and methylglyoxal-induced protein glycation and oxidative DNA damage. | 2016 | Int. J. Biol. Macromol. | pmid:27645922 |
| Strugała P et al. | Interaction between Mimic Lipid Membranes and Acylated and Nonacylated Cyanidin and Its Bioactivity. | 2016 | J. Agric. Food Chem. | pmid:27624410 |
| Grajeda-Iglesias C et al. | Isolation and Characterization of Anthocyanins from Hibiscus sabdariffa Flowers. | 2016 | J. Nat. Prod. | pmid:27312226 |
| Marques C et al. | Pharmacokinetics of blackberry anthocyanins consumed with or without ethanol: A randomized and crossover trial. | 2016 | Mol Nutr Food Res | pmid:27306520 |
| Camelo-Méndez GA et al. | Effect on in vitro starch digestibility of Mexican blue maize anthocyanins. | 2016 | Food Chem | pmid:27283633 |
| Santos FT et al. | Comparison of five agro-industrial waste-based composts as growing media for lettuce: Effect on yield, phenolic compounds and vitamin C. | 2016 | Food Chem | pmid:27173566 |
| Singh CK et al. | Combination chemoprevention with grape antioxidants. | 2016 | Mol Nutr Food Res | pmid:26829056 |
| Ahmadiani N et al. | Molar absorptivity (ε) and spectral characteristics of cyanidin-based anthocyanins from red cabbage. | 2016 | Food Chem | pmid:26617032 |
| Natarajan T et al. | Idaein chloride induced p53 dependent apoptosis in cervical cancer cells through inhibition of viral oncoproteins. | 2016 | Biochimie | pmid:26586108 |
| Liao J et al. | Identification and analysis of anthocyanin components in fruit color variation in Schisandra chinensis. | 2016 | J. Sci. Food Agric. | pmid:26493497 |
| Dou C et al. | Dual Effect of Cyanidin on RANKL-Induced Differentiation and Fusion of Osteoclasts. | 2016 | J. Cell. Physiol. | pmid:25545964 |
| Thummayot S et al. | Neuroprotective effects of cyanidin against Aβ-induced oxidative and ER stress in SK-N-SH cells. | 2016 | Neurochem. Int. | pmid:27697517 |
| Del Bo' C et al. | Different effects of anthocyanins and phenolic acids from wild blueberry (Vaccinium angustifolium) on monocytes adhesion to endothelial cells in a TNF-α stimulated proinflammatory environment. | 2016 | Mol Nutr Food Res | pmid:27324255 |
| Pantelić MM et al. | Identification and quantification of phenolic compounds in berry skin, pulp, and seeds in 13 grapevine varieties grown in Serbia. | 2016 | Food Chem | pmid:27283628 |