Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| He YH et al. | [Antioxidant and anti-inflammatory effects of cyanidin from cherries on rat adjuvant-induced arthritis]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16422543 |
| Felgines C et al. | Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans. | 2005 | J. Agric. Food Chem. | pmid:16190623 |
| Stoner GD et al. | Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days. | 2005 | J Clin Pharmacol | pmid:16172180 |
| Al-Farsi M et al. | Comparison of antioxidant activity, anthocyanins, carotenoids, and phenolics of three native fresh and sun-dried date (Phoenix dactylifera L.) varieties grown in Oman. | 2005 | J. Agric. Food Chem. | pmid:16159191 |
| Habermeyer M et al. | Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity. | 2005 | Chem. Res. Toxicol. | pmid:16167831 |
| Russo A et al. | Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-beta-d-glucoside. | 2005 | J. Nutr. Biochem. | pmid:15629238 |
| Galvano F et al. | Cyanidins: metabolism and biological properties. | 2004 | J. Nutr. Biochem. | pmid:14711454 |
| Zhang J et al. | The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus. | 2004 | Free Radic. Biol. Med. | pmid:15336320 |
| Hyun JW and Chung HS | Cyanidin and Malvidin from Oryza sativa cv. Heugjinjubyeo mediate cytotoxicity against human monocytic leukemia cells by arrest of G(2)/M phase and induction of apoptosis. | 2004 | J. Agric. Food Chem. | pmid:15080622 |
| Ueda H et al. | A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. | 2004 | Biosci. Biotechnol. Biochem. | pmid:14745173 |
| Tsuda T et al. | Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15003523 |
| Wu X et al. | Pelargonidin is absorbed and metabolized differently than cyanidin after marionberry consumption in pigs. | 2004 | J. Nutr. | pmid:15465754 |
| Xu JW et al. | Cyanidin-3-glucoside regulates phosphorylation of endothelial nitric oxide synthase. | 2004 | FEBS Lett. | pmid:15358561 |
| Harada K et al. | Absorption of acylated anthocyanins in rats and humans after ingesting an extract of Ipomoea batatas purple sweet potato tuber. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15277754 |
| Xu JW et al. | Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment. | 2004 | Hypertension | pmid:15226277 |
| Tatsuzawa F et al. | Diacylated 8-C-glucosylcyanidin 3-glucoside from the flowers of Tricyrtis formosana. | 2004 | Chem. Pharm. Bull. | pmid:15133223 |
| Matsumoto M et al. | Gastroprotective effect of red pigments in black chokeberry fruit (Aronia melanocarpa Elliot) on acute gastric hemorrhagic lesions in rats. | 2004 | J. Agric. Food Chem. | pmid:15080625 |
| Scordino M et al. | Adsorption of flavonoids on resins: cyanidin 3-glucoside. | 2004 | J. Agric. Food Chem. | pmid:15053537 |
| Ando T et al. | Delphinidin accumulation is associated with abnormal flower development in petunias. | 2004 | Phytochemistry | pmid:15587706 |
| Hillebrand S et al. | Characterization of anthocyanins and pyranoanthocyanins from blood orange [Citrus sinensis (L.) Osbeck] juice. | 2004 | J. Agric. Food Chem. | pmid:15563216 |
| Iwai K et al. | Physiological effects and active ingredients of Viburnum dilatatum Thunb fruits on oxidative stress. | 2004 | Biofactors | pmid:15630210 |
| Lee J et al. | Comparison of anthocyanin pigment and other phenolic compounds of Vaccinium membranaceum and Vaccinium ovatum native to the Pacific Northwest of North America. | 2004 | J. Agric. Food Chem. | pmid:15537315 |
| Chang Q and Wong YS | Identification of flavonoids in Hakmeitau beans (Vigna sinensis) by high-performance liquid chromatography-electrospray mass spectrometry (LC-ESI/MS). | 2004 | J. Agric. Food Chem. | pmid:15506802 |
| Muñoz-Espada AC et al. | Anthocyanin quantification and radical scavenging capacity of Concord, Norton, and Marechal Foch grapes and wines. | 2004 | J. Agric. Food Chem. | pmid:15506816 |
| Nimal Punyasiri PA et al. | Exobasidium vexans infection of Camellia sinensis increased 2,3-cis isomerisation and gallate esterification of proanthocyanidins. | 2004 | Phytochemistry | pmid:15504433 |
| Määttä-Riihinen KR et al. | Identification and quantification of phenolic compounds in berries of Fragaria and Rubus species (family Rosaceae). | 2004 | J. Agric. Food Chem. | pmid:15453684 |
| Aumont V et al. | Production of highly 13C-labeled polyphenols in Vitis vinifera cell bioreactor cultures. | 2004 | J. Biotechnol. | pmid:15066766 |
| Zhao C et al. | Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumorigenic colonic cell growth. | 2004 | J. Agric. Food Chem. | pmid:15453676 |
| Zhang Z et al. | Comparison of HPLC methods for determination of anthocyanins and anthocyanidins in bilberry extracts. | 2004 | J. Agric. Food Chem. | pmid:14969517 |
| Matsufuji H and Shibamoto T | Inhibition of malonaldehyde formation in oxidized calf thymus DNA with synthetic and natural antioxidants. | 2004 | J. Agric. Food Chem. | pmid:15373421 |
| Lee JH and Talcott ST | Fruit maturity and juice extraction influences ellagic acid derivatives and other antioxidant polyphenolics in muscadine grapes. | 2004 | J. Agric. Food Chem. | pmid:14733522 |
| Marko D et al. | The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation. | 2004 | Mol Nutr Food Res | pmid:15497183 |
| Schwarz M et al. | Isolation and identification of novel pyranoanthocyanins from black carrot (Daucus carota L.) juice. | 2004 | J. Agric. Food Chem. | pmid:15291481 |
| Kay CD et al. | Anthocyanin metabolites in human urine and serum. | 2004 | Br. J. Nutr. | pmid:15228048 |
| Chun OK et al. | Antioxidant properties of raw and processed cabbages. | 2004 | Int J Food Sci Nutr | pmid:15223595 |
| Turker N et al. | Effect of storage temperature on the stability of anthocyanins of a fermented black carrot (Daucus carota var. L.) beverage: shalgam. | 2004 | J. Agric. Food Chem. | pmid:15186101 |
| Romero C et al. | Polyphenol changes during fermentation of naturally black olives. | 2004 | J. Agric. Food Chem. | pmid:15053538 |
| Del Pozo-Insfran D et al. | Phytochemical composition and pigment stability of Açai (Euterpe oleracea Mart.). | 2004 | J. Agric. Food Chem. | pmid:15030208 |
| Lazzè MC et al. | Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. | 2004 | Carcinogenesis | pmid:15016660 |
| Sugita O et al. | A new method of measuring the antioxidant activity of polyphenols using cumene hydroperoxide. | 2004 | Ann. Clin. Biochem. | pmid:14713390 |
| Yousef GG et al. | Biosynthesis and characterization of 14C-enriched flavonoid fractions from plant cell suspension cultures. | 2004 | J. Agric. Food Chem. | pmid:14995111 |
| Chaovanalikit A et al. | Characterization and quantification of anthocyanins and polyphenolics in bluehHoneysuckle (Lonicera caerulea L.). | 2004 | J. Agric. Food Chem. | pmid:14969540 |
| Gonçalves B et al. | Effect of ripeness and postharvest storage on the phenolic profiles of Cherries (Prunus avium L.). | 2004 | J. Agric. Food Chem. | pmid:14759143 |
| Beckwith AG et al. | Relationship of light quantity and anthocyanin production in Pennisetum setaceum Cvs. rubrum and red riding hood. | 2004 | J. Agric. Food Chem. | pmid:14759132 |
| Fimognari C et al. | Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens. | 2004 | Environ. Mol. Mutagen. | pmid:14743345 |
| Xie DY et al. | Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana. | 2004 | Arch. Biochem. Biophys. | pmid:14725861 |
| Wang LS et al. | Chemical taxonomy of the Xibei tree peony from China by floral pigmentation. | 2004 | J. Plant Res. | pmid:14685820 |
| Di Paola-Naranjo RD et al. | Liquid chromatographic-mass spectrometric analysis of anthocyanin composition of dark blue bee pollen from Echium plantagineum. | 2004 | J Chromatogr A | pmid:15553145 |
| Glei M et al. | Initial in vitro toxicity testing of functional foods rich in catechins and anthocyanins in human cells. | 2003 Oct-Dec | Toxicol In Vitro | pmid:14599469 |
| Wolfe KL and Liu RH | Apple peels as a value-added food ingredient. | 2003 | J. Agric. Food Chem. | pmid:12617604 |