Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Santos FT et al. | Comparison of five agro-industrial waste-based composts as growing media for lettuce: Effect on yield, phenolic compounds and vitamin C. | 2016 | Food Chem | pmid:27173566 |
| Sigurdson GT et al. | Evaluating the role of metal ions in the bathochromic and hyperchromic responses of cyanidin derivatives in acidic and alkaline pH. | 2016 | Food Chem | pmid:27132820 |
| Pantelić MM et al. | Identification and quantification of phenolic compounds in berry skin, pulp, and seeds in 13 grapevine varieties grown in Serbia. | 2016 | Food Chem | pmid:27283628 |
| Lai YS et al. | The Dark-Purple Tea Cultivar 'Ziyan' Accumulates a Large Amount of Delphinidin-Related Anthocyanins. | 2016 | J. Agric. Food Chem. | pmid:26996195 |
| Lee SG et al. | Contribution of Anthocyanin Composition to Total Antioxidant Capacity of Berries. | 2015 | Plant Foods Hum Nutr | pmid:26515081 |
| Riha J et al. | Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes. | 2015 | Food Funct | pmid:25578040 |
| Iliopoulou I et al. | Analysis of the Thermal Degradation of the Individual Anthocyanin Compounds of Black Carrot (Daucus carota L.): A New Approach Using High-Resolution Proton Nuclear Magnetic Resonance Spectroscopy. | 2015 | J. Agric. Food Chem. | pmid:26160425 |
| Faramarzi S et al. | Red-fleshed Apples: Old Autochthonous Fruits as a Novel Source of Anthocyanin Antioxidants. | 2015 | Plant Foods Hum Nutr | pmid:26134879 |
| Lima Mdos S et al. | Phenolic compounds, organic acids and antioxidant activity of grape juices produced in industrial scale by different processes of maceration. | 2015 | Food Chem | pmid:26041208 |
| Antolak H et al. | Adhesion of Asaia bogorensis to Glass and Polystyrene in the Presence of Cranberry Juice. | 2015 | J. Food Prot. | pmid:26038911 |
| Jo YH et al. | Metabolomic Analysis Reveals Cyanidins in Black Raspberry as Candidates for Suppression of Lipopolysaccharide-Induced Inflammation in Murine Macrophages. | 2015 | J. Agric. Food Chem. | pmid:26023864 |
| Li DW et al. | Attenuation of Cisplatin-Induced Neurotoxicity by Cyanidin, a Natural Inhibitor of ROS-Mediated Apoptosis in PC12 Cells. | 2015 | Cell. Mol. Neurobiol. | pmid:25895624 |
| Moriya C et al. | New acylated anthocyanins from purple yam and their antioxidant activity. | 2015 | Biosci. Biotechnol. Biochem. | pmid:25848974 |
| Zhang C et al. | Binding characteristics and protective capacity of cyanidin-3-glucoside and its aglycon to calf thymus DNA. | 2015 | J. Food Sci. | pmid:25810071 |
| Li SY et al. | Association between modification of phenolic profiling and development of wine color during alcohol fermentation. | 2015 | J. Food Sci. | pmid:25807971 |
| An CH et al. | Heterologous expression of IbMYB1a by different promoters exhibits different patterns of anthocyanin accumulation in tobacco. | 2015 | Plant Physiol. Biochem. | pmid:25681576 |
| Scheit K and Bauer G | Direct and indirect inactivation of tumor cell protective catalase by salicylic acid and anthocyanidins reactivates intercellular ROS signaling and allows for synergistic effects. | 2015 | Carcinogenesis | pmid:25653236 |
| Lim A et al. | Potential natural sensitizers extracted from the skin of Canarium odontophyllum fruits for dye-sensitized solar cells. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25541396 |
| Zhang H et al. | Phenolic compounds and antioxidant properties of breeding lines between the white and black rice. | 2015 | Food Chem | pmid:25442600 |
| Du C et al. | Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells. | 2015 | Drug Des Devel Ther | pmid:26379423 |
| Kadigamuwa CC et al. | 2, 2'- and 4, 4'-Cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPPâº. | 2015 | J. Neurochem. | pmid:26094622 |
| Ahn JH et al. | De Novo Transcriptome Analysis to Identify Anthocyanin Biosynthesis Genes Responsible for Tissue-Specific Pigmentation in Zoysiagrass (Zoysia japonica Steud.). | 2015 | PLoS ONE | pmid:25905914 |
| Kim RJ et al. | Antioxidant's cytoprotective effects on rotator cuff tenofibroblasts exposed to aminoamide local anesthetics. | 2015 | J. Orthop. Res. | pmid:25639557 |
| Khandelwal N and Abraham SK | Protective effects of common anthocyanidins against genotoxic damage induced by chemotherapeutic drugs in mice. | 2014 | Planta Med. | pmid:25184891 |
| Harb J et al. | Changes in polyphenols and expression levels of related genes in 'Duke' blueberries stored under high CO2 levels. | 2014 | J. Agric. Food Chem. | pmid:24999801 |
| Miladinović B et al. | Chemical profile and antioxidative and antimicrobial activity of juices and extracts of 4 black currants varieties (Ribes nigrum L.). | 2014 | J. Food Sci. | pmid:24506271 |
| Thummayot S et al. | Neuroprotective effect of purple rice extract and its constituent against amyloid beta-induced neuronal cell death in SK-N-SH cells. | 2014 | Neurotoxicology | pmid:25451968 |
| Scheit K and Bauer G | Synergistic effects between catalase inhibitors and modulators of nitric oxide metabolism on tumor cell apoptosis. | 2014 | Anticancer Res. | pmid:25275027 |
| Xie Q et al. | Accumulation and molecular regulation of anthocyanin in purple tumorous stem mustard (Brassica juncea var. tumida Tsen et Lee). | 2014 | J. Agric. Food Chem. | pmid:25055052 |
| Khandelwal N and Abraham SK | Intake of anthocyanidins pelargonidin and cyanidin reduces genotoxic stress in mice induced by diepoxybutane, urethane and endogenous nitrosation. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24642102 |
| Khaodee W et al. | Effectively simultaneous naked-eye detection of Cu(II), Pb(II), Al(III) and Fe(III) using cyanidin extracted from red cabbage as chelating agent. | 2014 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:24594882 |
| Park S et al. | Quantification of glucosinolates, anthocyanins, free amino acids, and vitamin C in inbred lines of cabbage (Brassica oleracea L.). | 2014 | Food Chem | pmid:24128451 |
| Sun LL et al. | Composition and antioxidant activity of the anthocyanins of the fruit of Berberis heteropoda Schrenk. | 2014 | Molecules | pmid:25415473 |
| Miosic S et al. | Dihydroflavonol 4-reductase genes encode enzymes with contrasting substrate specificity and show divergent gene expression profiles in Fragaria species. | 2014 | PLoS ONE | pmid:25393679 |
| Xu ZS et al. | Transcript profiling of structural genes involved in cyanidin-based anthocyanin biosynthesis between purple and non-purple carrot (Daucus carota L.) cultivars reveals distinct patterns. | 2014 | BMC Plant Biol. | pmid:25269413 |
| Cheng DM et al. | Development and phytochemical characterization of high polyphenol red lettuce with anti-diabetic properties. | 2014 | PLoS ONE | pmid:24637790 |
| Sui X and Zhou W | Monte Carlo modelling of non-isothermal degradation of two cyanidin-based anthocyanins in aqueous system at high temperatures and its impact on antioxidant capacities. | 2014 | Food Chem | pmid:24262567 |
| Austin HR et al. | Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24393842 |
| Chen R et al. | Effects of the vegetable polyphenols epigallocatechin-3-gallate, luteolin, apigenin, myricetin, quercetin, and cyanidin in primary cultures of human retinal pigment epithelial cells. | 2014 | Mol. Vis. | pmid:24623967 |
| Bijak M et al. | Thrombin inhibitory activity of some polyphenolic compounds. | 2014 | Med Chem Res | pmid:24610996 |
| Kim RJ et al. | Do antioxidants inhibit oxidative-stress-induced autophagy of tenofibroblasts? | 2014 | J. Orthop. Res. | pmid:24644146 |
| Xia N et al. | Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells. | 2014 | Molecules | pmid:24662080 |
| Ogawa K et al. | Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro. | 2014 | BMC Complement Altern Med | pmid:24690313 |
| Chao PY et al. | Inhibitive effect of purple sweet potato leaf extract and its components on cell adhesion and inflammatory response in human aortic endothelial cells. | 2013 Mar-Apr | Cell Adh Migr | pmid:23466865 |
| Huang XW et al. | A new sensor for ammonia based on cyanidin-sensitized titanium dioxide film operating at room temperature. | 2013 | Anal. Chim. Acta | pmid:23830444 |
| Bushakra JM et al. | QTL involved in the modification of cyanidin compounds in black and red raspberry fruit. | 2013 | Theor. Appl. Genet. | pmid:23224381 |
| Gharib A et al. | In vitro and in vivo antibacterial activities of cyanidinum chloride-loaded liposomes against a resistant strain of Pseudomonas aeruginosa. | 2013 | Planta Med. | pmid:23203413 |
| Elisabetta B et al. | Nutritional profile and productivity of bilberry (Vaccinium myrtillus L.) in different habitats of a protected area of the eastern Italian Alps. | 2013 | J. Food Sci. | pmid:23573813 |
| Brugliera F et al. | Violet/blue chrysanthemums--metabolic engineering of the anthocyanin biosynthetic pathway results in novel petal colors. | 2013 | Plant Cell Physiol. | pmid:23926066 |
| Gharib A et al. | Treatment of diabetes in the mouse model by delphinidin and cyanidin hydrochloride in free and liposomal forms. | 2013 | Planta Med. | pmid:24108435 |