Cyanidin

Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cyanidin?

Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Cyanidin

PubChem Associated disorders and diseases

What pathways are associated with Cyanidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cyanidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Cyanidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cyanidin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Cyanidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Cyanidin?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Animal Disease Models

Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Cyanidin

Download all related citations
Per page 10 20 50 100 | Total 859
Authors Title Published Journal PubMed Link
Zhu W et al. The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP-PKA-dependent signaling pathway. 2012 Free Radic. Biol. Med. pmid:22085656
Ramirez-Tortosa C et al. Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats. 2001 Free Radic. Biol. Med. pmid:11677035
De Rosso VV et al. Singlet oxygen quenching by anthocyanin's flavylium cations. 2008 Free Radic. Res. pmid:18985487
Rahman MM et al. Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. 2006 Free Radic. Res. pmid:17015281
Sharma M et al. Identification of the pr1 gene product completes the anthocyanin biosynthesis pathway of maize. 2011 Genetics pmid:21385724
Li S and Yao J [Adsorption dynamics study on interactions of pigments and human whole saliva]. 2012 Hua Xi Kou Qiang Yi Xue Za Zhi pmid:22768757
Xu JW et al. Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment. 2004 Hypertension pmid:15226277
Omoigui S The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. 2007 Immun Ageing pmid:17374166
Rajani GP and Ashok P In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. 2009 Indian J Pharmacol pmid:20177495
Gastrointestinal pharmacology. 2008 Indian J Pharmacol pmid:21593966
Zhang Y et al. Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. 2010 Inflamm. Res. pmid:20309718
Devi PS et al. Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7). 2011 Int J Breast Cancer pmid:22312562
Reber JD et al. Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries. 2011 Int J Food Sci Nutr pmid:21385007
Bononi M et al. 'Cyanidin volumetric index' and 'chromaticity coordinates ratio' to characterize red raspberry (Rubus idaeus). 2006 Aug-Sep Int J Food Sci Nutr pmid:17135027
Butryee C et al. Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf. 2009 Int J Food Sci Nutr pmid:19572229
Chun OK et al. Antioxidant properties of raw and processed cabbages. 2004 Int J Food Sci Nutr pmid:15223595
Bononi M and Tateo F Stabilization of cranberry anthocyanins in nutraceutical capsules. 2007 Int J Food Sci Nutr pmid:17469769
D'Archivio M et al. Bioavailability of the polyphenols: status and controversies. 2010 Int J Mol Sci pmid:20480022
Wei S et al. Concentration of rutin model solutions from their mixtures with glucose using ultrafiltration. 2010 Int J Mol Sci pmid:20386660
Tanaka T et al. Chemistry of secondary polyphenols produced during processing of tea and selected foods. 2009 Int J Mol Sci pmid:20161999
Halbwirth H The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. 2010 Int J Mol Sci pmid:20386656
Philpott M et al. Dietary protection against free radicals: a case for multiple testing to establish structure-activity relationships for antioxidant potential of anthocyanic plant species. 2009 Int J Mol Sci pmid:19399239
Kimura Y et al. Synthesis of 8-Aryl-O-methylcyanidins and Their Usage for Dye-Sensitized Solar Cell Devices. 2017 Int J Mol Sci pmid:28212330
Zhu L et al. Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. 2012 Int J Mol Sci pmid:22489164
de Jesus NZ et al. Tannins, peptic ulcers and related mechanisms. 2012 Int J Mol Sci pmid:22489149
Mazzio EA et al. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. 2011 Int J Mol Sci pmid:21340000
Akkarachiyasit S et al. Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase. 2010 Int J Mol Sci pmid:20957102
Zhao Q et al. Anthocyanins profile of grape berries of Vitis amurensis, its hybrids and their wines. 2010 Int J Mol Sci pmid:20559511
de Pascual-Teresa S et al. Flavanols and anthocyanins in cardiovascular health: a review of current evidence. 2010 Int J Mol Sci pmid:20480037
Treutter D Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. 2010 Int J Mol Sci pmid:20479987
Tanaka Y et al. Recent progress of flower colour modification by biotechnology. 2009 Int J Mol Sci pmid:20054474
Ghanbari R et al. Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. 2012 Int J Mol Sci pmid:22489153
Roslan ND et al. Flavonoid biosynthesis genes putatively identified in the aromatic plant Polygonum minus via Expressed Sequences Tag (EST) analysis. 2012 Int J Mol Sci pmid:22489118
Arfan M et al. Antioxidant activity of mulberry fruit extracts. 2012 Int J Mol Sci pmid:22408465
Bak MJ et al. Procyanidins from wild grape (Vitis amurensis) seeds regulate ARE-mediated enzyme expression via Nrf2 coupled with p38 and PI3K/Akt pathway in HepG2 cells. 2012 Int J Mol Sci pmid:22312287
Ibrahim MH et al. Involvement of nitrogen on flavonoids, glutathione, anthocyanin, ascorbic acid and antioxidant activities of Malaysian medicinal plant Labisia pumila Blume (Kacip Fatimah). 2012 Int J Mol Sci pmid:22312260
Panickar KS and Anderson RA Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. 2011 Int J Mol Sci pmid:22174658
Abidi W et al. Evaluation of antioxidant compounds and total sugar content in a nectarine [Prunus persica (L.) Batsch] progeny. 2011 Int J Mol Sci pmid:22072927
Wu X et al. Optimization of phenolic antioxidant extraction from Wuweizi (Schisandra chinensis) pulp using random-centroid optimazation methodology. 2011 Int J Mol Sci pmid:22016656
Zou TB et al. Optimization of ultrasound-assisted extraction of anthocyanins from mulberry, using response surface methodology. 2011 Int J Mol Sci pmid:21686165
Wei SD et al. Antioxidant activities of fractions of polymeric procyanidins from stem bark of Acacia confusa. 2011 Int J Mol Sci pmid:21541049
Titta L et al. Blood orange juice inhibits fat accumulation in mice. 2010 Int J Obes (Lond) pmid:20029381
Min SW et al. Anti-inflammatory effects of black rice, cyanidin-3-O-beta-D-glycoside, and its metabolites, cyanidin and protocatechuic acid. 2010 Int. Immunopharmacol. pmid:20669401
Suantawee T et al. Protective effect of cyanidin against glucose- and methylglyoxal-induced protein glycation and oxidative DNA damage. 2016 Int. J. Biol. Macromol. pmid:27645922
Cooke D et al. Effect of cyanidin-3-glucoside and an anthocyanin mixture from bilberry on adenoma development in the ApcMin mouse model of intestinal carcinogenesis--relationship with tissue anthocyanin levels. 2006 Int. J. Cancer pmid:16823841
Lacombe A et al. Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7. 2010 Int. J. Food Microbiol. pmid:20153540
Kyselova Z Toxicological aspects of the use of phenolic compounds in disease prevention. 2011 Interdiscip Toxicol pmid:22319251
Milbury PE et al. Bilberry (Vaccinium myrtillus) anthocyanins modulate heme oxygenase-1 and glutathione S-transferase-pi expression in ARPE-19 cells. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17460300
Barzaghi N et al. Protective effect of cyanidin (IdB 1027) against aspirin-induced fall in gastric transmucosal potential difference in normal subjects. 1991 Ital J Gastroenterol pmid:1742514
Cassinese C et al. New liquid chromatography method with ultraviolet detection for analysis of anthocyanins and anthocyanidins in Vaccinium myrtillus fruit dry extracts and commercial preparations. 2007 Jul-Aug J AOAC Int pmid:17760327
Coates EM et al. Colon-available raspberry polyphenols exhibit anti-cancer effects on in vitro models of colon cancer. 2007 J Carcinog pmid:17442116
Füzfai Z and Molnár-Perl I Gas chromatographic-mass spectrometric fragmentation study of flavonoids as their trimethylsilyl derivatives: analysis of flavonoids, sugars, carboxylic and amino acids in model systems and in citrus fruits. 2007 J Chromatogr A pmid:17289064
Di Paola-Naranjo RD et al. Liquid chromatographic-mass spectrometric analysis of anthocyanin composition of dark blue bee pollen from Echium plantagineum. 2004 J Chromatogr A pmid:15553145
Adisakwattana S et al. Cyanidin-3-rutinoside alleviates postprandial hyperglycemia and its synergism with acarbose by inhibition of intestinal α-glucosidase. 2011 J Clin Biochem Nutr pmid:21765605
Okazaki Y et al. A beverage containing fermented black soybean ameliorates ferric nitrilotriacetate-induced renal oxidative damage in rats. 2010 J Clin Biochem Nutr pmid:21103028
Noda Y et al. Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine. 2008 J Clin Biochem Nutr pmid:19015753
Maruyama C et al. Azuki bean juice lowers serum triglyceride concentrations in healthy young women. 2008 J Clin Biochem Nutr pmid:18648655
Stoner GD et al. Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days. 2005 J Clin Pharmacol pmid:16172180
Frank T et al. Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract. 2005 J Clin Pharmacol pmid:15647413
Adisakwattana S et al. alpha-Glucosidase inhibitory activity of cyanidin-3-galactoside and synergistic effect with acarbose. 2009 J Enzyme Inhib Med Chem pmid:18615280
Lans C et al. Ethnoveterinary medicines used for ruminants in British Columbia, Canada. 2007 J Ethnobiol Ethnomed pmid:17324258
Ojeda D et al. Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa. 2010 J Ethnopharmacol pmid:19808084
Kuehl KS et al. Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial. 2010 J Int Soc Sports Nutr pmid:20459662
Li JB et al. A new acylated anthocyanin from the red flowers of Camellia hongkongensis and characterization of anthocyanins in the section Camellia species. 2009 J Integr Plant Biol pmid:19522813
Zhang J et al. Determination of anthocyanins and exploration of relationship between their composition and petal coloration in crape myrtle (Lagerstroemia hybrid). 2008 J Integr Plant Biol pmid:18713426
Kim KT et al. Neuroprotective effect of anthocyanin on experimental traumatic spinal cord injury. 2011 J Korean Neurosurg Soc pmid:21607177
Pawlak K et al. Blue natural organic dyestuffs--from textile dyeing to mural painting. Separation and characterization of coloring matters present in elderberry, logwood and indigo. 2006 J Mass Spectrom pmid:16575781
Flamini R Some advances in the knowledge of grape, wine and distillates chemistry as achieved by mass spectrometry. 2005 J Mass Spectrom pmid:15954164
Alcalde-Eon C et al. Identification of dimeric anthocyanins and new oligomeric pigments in red wine by means of HPLC-DAD-ESI/MSn. 2007 J Mass Spectrom pmid:17511019
Ju JH et al. Anti-obesity and antioxidative effects of purple sweet potato extract in 3T3-L1 adipocytes in vitro. 2011 J Med Food pmid:21861722
Kim AJ and Park S Mulberry extract supplements ameliorate the inflammation-related hematological parameters in carrageenan-induced arthritic rats. 2006 J Med Food pmid:17004912
Korte G et al. An examination of anthocyanins' and anthocyanidins' affinity for cannabinoid receptors. 2009 J Med Food pmid:20041802
Herath HM et al. Inhibitory effect of some flavonoids on tumor necrosis factor-alpha production in lipopolysaccharide-stimulated mouse macrophage cell line J774.1. 2003 J Med Food pmid:14977446
Sun CD et al. Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic β cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice. 2012 J Med Food pmid:22181073
Dani C et al. Protective effects of purple grape juice on carbon tetrachloride-induced oxidative stress in brains of adult Wistar rats. 2008 J Med Food pmid:18361738
Dreiseitel A et al. sPhospholipase A(2) is inhibited by anthocyanidins. 2009 J Neural Transm (Vienna) pmid:19649692
Giordano L et al. Development and validation of an LC-MS/MS analysis for simultaneous determination of delphinidin-3-glucoside, cyanidin-3-glucoside and cyanidin-3-(6-malonylglucoside) in human plasma and urine after blood orange juice administration. 2007 J Sep Sci pmid:18027360
Choi JY et al. Analysis and tentative structure elucidation of new anthocyanins in fruit peel of Vitis coignetiae Pulliat (meoru) using LC-MS/MS: Contribution to the overall antioxidant activity. 2010 J Sep Sci pmid:20187032
Qiu F et al. Preparative isolation and purification of anthocyanins from purple sweet potato by high-speed counter-current chromatography. 2009 J Sep Sci pmid:19479751
Comandini P et al. CZE separation of strawberry anthocyanins with acidic buffer and comparison with HPLC. 2008 J Sep Sci pmid:18704996
Marin-Kuan M et al. Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a. 2011 J Toxicol pmid:21776264
Huang WY et al. Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing. 2012 J Zhejiang Univ Sci B pmid:22302422
Li X et al. Accumulation of phenylpropanoids and correlated gene expression during the development of tartary buckwheat sprouts. 2012 J. Agric. Food Chem. pmid:22587625
Tsao R et al. Polyphenolic profiles in eight apple cultivars using high-performance liquid chromatography (HPLC). 2003 J. Agric. Food Chem. pmid:14518966
Jo YH et al. Metabolomic Analysis Reveals Cyanidins in Black Raspberry as Candidates for Suppression of Lipopolysaccharide-Induced Inflammation in Murine Macrophages. 2015 J. Agric. Food Chem. pmid:26023864
Kanamoto Y et al. A black soybean seed coat extract prevents obesity and glucose intolerance by up-regulating uncoupling proteins and down-regulating inflammatory cytokines in high-fat diet-fed mice. 2011 J. Agric. Food Chem. pmid:21751816
Josuttis M et al. Solar UVB response of bioactives in strawberry (Fragaria × ananassa Duch. L.): a comparison of protected and open-field cultivation. 2010 J. Agric. Food Chem. pmid:21086998
Li X et al. Purple canola: Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. 2010 J. Agric. Food Chem. pmid:20073469
White BL et al. Proximate and polyphenolic characterization of cranberry pomace. 2010 J. Agric. Food Chem. pmid:20020689
Treutter D et al. Diversity of phenolic profiles in the fruit skin of Prunus domestica plums and related species. 2012 J. Agric. Food Chem. pmid:23140499
Harb J et al. Correlation between changes in polyphenol composition of peels and incidence of COâ‚‚ skin burning of 'Cameo' apples as influenced by controlled atmosphere storage. 2013 J. Agric. Food Chem. pmid:23517081
Persson IA et al. Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. 2009 J. Agric. Food Chem. pmid:19441816
Nicoletti I et al. Identification and quantification of phenolic compounds in grapes by HPLC-PDA-ESI-MS on a semimicro separation scale. 2008 J. Agric. Food Chem. pmid:18781764
Hosseinian FS and Beta T Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries. 2007 J. Agric. Food Chem. pmid:18052240
Frank J et al. Effects of dietary anthocyanins on tocopherols and lipids in rats. 2002 J. Agric. Food Chem. pmid:12452636
Jordheim M et al. Molar absorptivities and reducing capacity of pyranoanthocyanins and other anthocyanins. 2007 J. Agric. Food Chem. pmid:18047275
Tian Q et al. Urinary excretion of black raspberry (Rubus occidentalis) anthocyanins and their metabolites. 2006 J. Agric. Food Chem. pmid:16478275
Yoshimura Y et al. Evaluation of the NO scavenging activity of procyanidin in grape seed by use of the TMA-PTIO/NOC 7 ESR system. 2003 J. Agric. Food Chem. pmid:14558755
Schwarz M et al. Isolation and identification of novel pyranoanthocyanins from black carrot (Daucus carota L.) juice. 2004 J. Agric. Food Chem. pmid:15291481
Eiro MJ and Heinonen M Anthocyanin color behavior and stability during storage: effect of intermolecular copigmentation. 2002 J. Agric. Food Chem. pmid:12452676