Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gao S et al. | Cyanidin reverses cisplatin-induced apoptosis in HK-2 proximal tubular cells through inhibition of ROS-mediated DNA damage and modulation of the ERK and AKT pathways. | 2013 | Cancer Lett. | pmid:23360684 |
| Tanaka J et al. | Purple rice extract and its constituents suppress endoplasmic reticulum stress-induced retinal damage in vitro and in vivo. | 2013 | Life Sci. | pmid:23123597 |
| Chu H et al. | Expression of the sweetpotato R2R3-type IbMYB1a gene induces anthocyanin accumulation in Arabidopsis. | 2013 | Physiol Plant | pmid:23039825 |
| Harb J et al. | Correlation between changes in polyphenol composition of peels and incidence of COâ‚‚ skin burning of 'Cameo' apples as influenced by controlled atmosphere storage. | 2013 | J. Agric. Food Chem. | pmid:23517081 |
| Xiao J et al. | Advance in dietary polyphenols as α-glucosidases inhibitors: a review on structure-activity relationship aspect. | 2013 | Crit Rev Food Sci Nutr | pmid:23768145 |
| Takahama U et al. | Isolation and characterization of a cyanidin-catechin pigment from adzuki bean (Vigna angularis). | 2013 | Food Chem | pmid:23768359 |
| Jia Y et al. | Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23769638 |
| Toffali K et al. | Carrot-specific features of the phenylpropanoid pathway identified by feeding cultured cells with defined intermediates. | 2013 | Plant Sci. | pmid:23759106 |
| Kuhn I et al. | Schistosoma mansoni NAD(+) catabolizing enzyme: identification of key residues in catalysis. | 2013 | Biochim. Biophys. Acta | pmid:24035885 |
| Takahama U et al. | Interactions of starch with a cyanidin-catechin pigment (vignacyanidin) isolated from Vigna angularis bean. | 2013 | Food Chem | pmid:23871000 |
| Vodopivec BM et al. | Differences in the structure of anthocyanins from the two amphibious plants, Lobelia cardinalis and Nesaea crassicaulis. | 2013 | Nat. Prod. Res. | pmid:22694738 |
| Elisabetta B et al. | Nutritional profile and productivity of bilberry (Vaccinium myrtillus L.) in different habitats of a protected area of the eastern Italian Alps. | 2013 | J. Food Sci. | pmid:23573813 |
| Brugliera F et al. | Violet/blue chrysanthemums--metabolic engineering of the anthocyanin biosynthetic pathway results in novel petal colors. | 2013 | Plant Cell Physiol. | pmid:23926066 |
| Gharib A et al. | Treatment of diabetes in the mouse model by delphinidin and cyanidin hydrochloride in free and liposomal forms. | 2013 | Planta Med. | pmid:24108435 |
| Pompei A et al. | Cyanidin reduces preadipocyte differentiation and relative ChREBP expression. | 2012 Apr-Jun | J. Biol. Regul. Homeost. Agents | pmid:22824753 |
| Wang Y et al. | Antioxidant activities and major anthocyanins of Myrobalan plum (Prunus cerasifera Ehrh.). | 2012 | J. Food Sci. | pmid:22432436 |
| Tanaka J et al. | Purple rice (Oryza sativa L.) extract and its constituents inhibit VEGF-induced angiogenesis. | 2012 | Phytother Res | pmid:21633982 |
| Arapitsas P et al. | A metabolomic approach to the study of wine micro-oxygenation. | 2012 | PLoS ONE | pmid:22662221 |
| Bonarska-Kujawa D et al. | Interaction of selected anthocyanins with erythrocytes and liposome membranes. | 2012 | Cell. Mol. Biol. Lett. | pmid:22396139 |
| Aguayo-Rojas J et al. | Phytochemicals and antioxidant capacity of tortillas obtained after lime-cooking extrusion process of whole pigmented mexican maize. | 2012 | Plant Foods Hum Nutr | pmid:22562094 |
| Wang D et al. | Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice. | 2012 | Mol Nutr Food Res | pmid:22495986 |
| Yuan L et al. | Molecular cloning and characterization of PtrLAR3, a gene encoding leucoanthocyanidin reductase from Populus trichocarpa, and its constitutive expression enhances fungal resistance in transgenic plants. | 2012 | J. Exp. Bot. | pmid:22268151 |
| Fernandes I et al. | A new approach on the gastric absorption of anthocyanins. | 2012 | Food Funct | pmid:22391951 |
| Ziberna L et al. | Transport and bioactivity of cyanidin 3-glucoside into the vascular endothelium. | 2012 | Free Radic. Biol. Med. | pmid:22387282 |
| Zou T et al. | Optimization of microwave-assisted extraction of anthocyanins from mulberry and identification of anthocyanins in extract using HPLC-ESI-MS. | 2012 | J. Food Sci. | pmid:22260102 |
| Zilić S et al. | Phenolic compounds, carotenoids, anthocyanins, and antioxidant capacity of colored maize (Zea mays L.) kernels. | 2012 | J. Agric. Food Chem. | pmid:22248075 |
| Guo H et al. | Cyanidin 3-glucoside attenuates obesity-associated insulin resistance and hepatic steatosis in high-fat diet-fed and db/db mice via the transcription factor FoxO1. | 2012 | J. Nutr. Biochem. | pmid:21543211 |
| Li J et al. | Purple corn anthocyanins dampened high-glucose-induced mesangial fibrosis and inflammation: possible renoprotective role in diabetic nephropathy. | 2012 | J. Nutr. Biochem. | pmid:21543205 |
| Ojwang LO et al. | Ultra performance liquid chromatography-tandem quadrupole mass spectrometry profiling of anthocyanins and flavonols in cowpea (Vigna unguiculata) of varying genotypes. | 2012 | J. Agric. Food Chem. | pmid:22429113 |
| Yoshimura Y et al. | Visualization of anthocyanin species in rabbiteye blueberry Vaccinium ashei by matrix-assisted laser desorption/ionization imaging mass spectrometry. | 2012 | Anal Bioanal Chem | pmid:22399120 |
| Romera-Fernández M et al. | Feasibility study of FT-MIR spectroscopy and PLS-R for the fast determination of anthocyanins in wine. | 2012 | Talanta | pmid:22265503 |
| Treutter D et al. | Diversity of phenolic profiles in the fruit skin of Prunus domestica plums and related species. | 2012 | J. Agric. Food Chem. | pmid:23140499 |
| Zhu L et al. | Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. | 2012 | Int J Mol Sci | pmid:22489164 |
| de Jesus NZ et al. | Tannins, peptic ulcers and related mechanisms. | 2012 | Int J Mol Sci | pmid:22489149 |
| Oloyede FM et al. | Effect of NPK fertilizer on chemical composition of pumpkin (Cucurbita pepo Linn.) seeds. | 2012 | ScientificWorldJournal | pmid:22629204 |
| Ghanbari R et al. | Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. | 2012 | Int J Mol Sci | pmid:22489153 |
| Guo H et al. | Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. | 2012 | Lipids Health Dis | pmid:22243683 |
| Rozza AL et al. | Morphologic and pharmacological investigations in the epicatechin gastroprotective effect. | 2012 | Evid Based Complement Alternat Med | pmid:22666296 |
| Mohanty S and Cock IE | The chemotherapeutic potential of Terminalia ferdinandiana: Phytochemistry and bioactivity. | 2012 | Pharmacogn Rev | pmid:22654402 |
| Taha RM and Wafa SN | Plant regeneration and cellular behaviour studies in Celosia cristata grown in vivo and in vitro. | 2012 | ScientificWorldJournal | pmid:22593677 |
| Kumar S et al. | Genomic selection for fruit quality traits in apple (Malus×domestica Borkh.). | 2012 | PLoS ONE | pmid:22574211 |
| Ganugapati J et al. | Molecular docking studies of banana flower flavonoids as insulin receptor tyrosine kinase activators as a cure for diabetes mellitus. | 2012 | Bioinformation | pmid:22493522 |
| Roslan ND et al. | Flavonoid biosynthesis genes putatively identified in the aromatic plant Polygonum minus via Expressed Sequences Tag (EST) analysis. | 2012 | Int J Mol Sci | pmid:22489118 |
| Chagné D et al. | QTL and candidate gene mapping for polyphenolic composition in apple fruit. | 2012 | BMC Plant Biol. | pmid:22269060 |
| Han Y et al. | Introduction of apple ANR genes into tobacco inhibits expression of both CHI and DFR genes in flowers, leading to loss of anthocyanin. | 2012 | J. Exp. Bot. | pmid:22238451 |
| Sun CD et al. | Cyanidin-3-glucoside-rich extract from Chinese bayberry fruit protects pancreatic β cells and ameliorates hyperglycemia in streptozotocin-induced diabetic mice. | 2012 | J Med Food | pmid:22181073 |
| Yonekura-Sakakibara K et al. | Two glycosyltransferases involved in anthocyanin modification delineated by transcriptome independent component analysis in Arabidopsis thaliana. | 2012 | Plant J. | pmid:21899608 |
| Duchnowicz P et al. | Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study). | 2012 | Eur J Nutr | pmid:21755326 |
| Crupi P et al. | HPLC-DAD-ESI-MS analysis of flavonoid compounds in 5 seedless table grapes grown in Apulian Region. | 2012 | J. Food Sci. | pmid:22309436 |
| Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |