Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yao JW et al. | Affinity interactions between natural pigments and human whole saliva. | 2011 | Arch. Oral Biol. | pmid:21112045 |
| Reber JD et al. | Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries. | 2011 | Int J Food Sci Nutr | pmid:21385007 |
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| Qaâdan F et al. | Polyphenols from Ginkgo biloba. | 2010 Oct-Dec | Sci Pharm | pmid:21179324 |
| Liu X et al. | Preparative separation and enrichment of syringopicroside from Folium syringae leaves with macroporous resins. | 2010 | J. Biomed. Biotechnol. | pmid:21234415 |
| Xu M et al. | Cyanidin-3-glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2. | 2010 | Mol. Cancer | pmid:21034468 |
| Ozgen M et al. | Total phenolic, anthocyanin contents and antioxidant capacity of selected elderberry (Sambucus canadensis L.) accessions. | 2010 | Pharmacogn Mag | pmid:20931079 |
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| Min SW et al. | Anti-inflammatory effects of black rice, cyanidin-3-O-beta-D-glycoside, and its metabolites, cyanidin and protocatechuic acid. | 2010 | Int. Immunopharmacol. | pmid:20669401 |
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| Ernst IM et al. | Cellular uptake, stability, visualization by 'Naturstoff reagent A', and multidrug resistance protein 1 gene-regulatory activity of cyanidin in human keratinocytes. | 2010 | Pharmacol. Res. | pmid:19897037 |
| Ojeda D et al. | Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa. | 2010 | J Ethnopharmacol | pmid:19808084 |
| Solomon A et al. | Protection of fibroblasts (NIH-3T3) against oxidative damage by cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). | 2010 | J. Agric. Food Chem. | pmid:20443626 |
| Shi MZ and Xie DY | Features of anthocyanin biosynthesis in pap1-D and wild-type Arabidopsis thaliana plants grown in different light intensity and culture media conditions. | 2010 | Planta | pmid:20309578 |
| Choi MJ et al. | Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system. | 2010 | Biol. Pharm. Bull. | pmid:20190403 |
| Kim JE et al. | Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. | 2010 | Biochem. Pharmacol. | pmid:20096264 |
| Wiczkowski W et al. | Bioavailability of cyanidin glycosides from natural chokeberry (Aronia melanocarpa) juice with dietary-relevant dose of anthocyanins in humans. | 2010 | J. Agric. Food Chem. | pmid:21067240 |
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| Josuttis M et al. | Solar UVB response of bioactives in strawberry (Fragaria × ananassa Duch. L.): a comparison of protected and open-field cultivation. | 2010 | J. Agric. Food Chem. | pmid:21086998 |
| Speciale A et al. | Cyanidin-3-O-glucoside protection against TNF-α-induced endothelial dysfunction: involvement of nuclear factor-κB signaling. | 2010 | J. Agric. Food Chem. | pmid:20958056 |
| Sentandreu E et al. | LC-DAD-ESI/MS(n) determination of direct condensation flavanol-anthocyanin adducts in pressure extracted pomegranate (Punica granatum L.) juice. | 2010 | J. Agric. Food Chem. | pmid:20839870 |
| Gill CI et al. | Profiling of phenols in human fecal water after raspberry supplementation. | 2010 | J. Agric. Food Chem. | pmid:20809621 |
| Salvatierra A et al. | Comparison of transcriptional profiles of flavonoid genes and anthocyanin contents during fruit development of two botanical forms of Fragaria chiloensis ssp. chiloensis. | 2010 | Phytochemistry | pmid:20800857 |
| Montilla EC et al. | Preparative isolation of anthocyanins from Japanese purple sweet potato (Ipomoea batatas L.) varieties by high-speed countercurrent chromatography. | 2010 | J. Agric. Food Chem. | pmid:20731350 |
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| Zhu F et al. | Anthocyanins, hydroxycinnamic acid derivatives, and antioxidant activity in roots of different chinese purple-fleshed sweetpotato genotypes. | 2010 | J. Agric. Food Chem. | pmid:20524661 |
| Cuevas-RodrÃguez EO et al. | Characterization of anthocyanins and proanthocyanidins in wild and domesticated Mexican blackberries (Rubus spp.). | 2010 | J. Agric. Food Chem. | pmid:20507066 |
| Liu J et al. | Bog bilberry (Vaccinium uliginosum L.) extract reduces cultured Hep-G2, Caco-2, and 3T3-L1 cell viability, affects cell cycle progression, and has variable effects on membrane permeability. | 2010 | J. Food Sci. | pmid:20492295 |
| Li Z et al. | Effects of exogenous abscisic acid on yield, antioxidant capacities, and phytochemical contents of greenhouse grown lettuces. | 2010 | J. Agric. Food Chem. | pmid:20420437 |
| Zhang Y et al. | Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. | 2010 | Inflamm. Res. | pmid:20309718 |
| Delazar A et al. | Isolation and free-radical-scavenging properties of cyanidin 3-O-glycosides from the fruits of Ribes biebersteinii Berl. | 2010 | Acta Pharm | pmid:20228037 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Felgines C et al. | Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse. | 2010 | Br. J. Nutr. | pmid:20187984 |
| Choi JY et al. | Analysis and tentative structure elucidation of new anthocyanins in fruit peel of Vitis coignetiae Pulliat (meoru) using LC-MS/MS: Contribution to the overall antioxidant activity. | 2010 | J Sep Sci | pmid:20187032 |
| Zhang Y et al. | Spectral alteration and degradation of cyanidin-3-glucoside exposed to pulsed electric field. | 2010 | J. Agric. Food Chem. | pmid:20163112 |
| Lacombe A et al. | Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7. | 2010 | Int. J. Food Microbiol. | pmid:20153540 |
| Tarozzi A et al. | Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25-35) oligomer-induced toxicity. | 2010 | Neurosci. Lett. | pmid:20152881 |
| Yamagishi M et al. | Two R2R3-MYB genes, homologs of Petunia AN2, regulate anthocyanin biosyntheses in flower Tepals, tepal spots and leaves of asiatic hybrid lily. | 2010 | Plant Cell Physiol. | pmid:20118109 |
| Behnke K et al. | RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. | 2010 | Plant Mol. Biol. | pmid:20526857 |
| Johnson ET et al. | Constitutive expression of the maize genes B1 and C1 in transgenic Hi II maize results in differential tissue pigmentation and generates resistance to Helicoverpa zea. | 2010 | J. Agric. Food Chem. | pmid:20108901 |
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| Truong VD et al. | Characterization of anthocyanins and anthocyanidins in purple-fleshed sweetpotatoes by HPLC-DAD/ESI-MS/MS. | 2010 | J. Agric. Food Chem. | pmid:20017481 |
| Chakraborty M et al. | Effect of the novel radiant zone drying method on anthocyanins and phenolics of three blueberry liquids. | 2010 | J. Agric. Food Chem. | pmid:19954224 |
| Zu XY et al. | Anthocyanins extracted from Chinese blueberry (Vaccinium uliginosum L.) and its anticancer effects on DLD-1 and COLO205 cells. | 2010 | Chin. Med. J. | pmid:21034658 |
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| Akkarachiyasit S et al. | Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase. | 2010 | Int J Mol Sci | pmid:20957102 |
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