Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Terahara N et al. | Functional new acylated sophoroses and deglucosylated anthocyanins in a fermented red vinegar. | 2009 | J. Agric. Food Chem. | pmid:19702267 |
| Rajani GP and Ashok P | In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. | 2009 | Indian J Pharmacol | pmid:20177495 |
| Tanaka T et al. | Chemistry of secondary polyphenols produced during processing of tea and selected foods. | 2009 | Int J Mol Sci | pmid:20161999 |
| Zikri NN et al. | Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. | 2009 | Nutr Cancer | pmid:20155622 |
| Lee SJ et al. | Grape skin improves antioxidant capacity in rats fed a high fat diet. | 2009 | Nutr Res Pract | pmid:20098580 |
| Payyavula RS et al. | Glycosylation-mediated phenylpropanoid partitioning in Populus tremuloides cell cultures. | 2009 | BMC Plant Biol. | pmid:20040108 |
| Bjorøy O et al. | C-glycosylanthocyanidins synthesized from C-glycosylflavones. | 2009 | Phytochemistry | pmid:19185884 |
| Gargouri M et al. | Binding-equilibrium and kinetic studies of anthocyanidin reductase from Vitis vinifera. | 2009 | Arch. Biochem. Biophys. | pmid:19772852 |
| Chen G et al. | Cyanidin-3-glucoside reverses ethanol-induced inhibition of neurite outgrowth: role of glycogen synthase kinase 3 Beta. | 2009 | Neurotox Res | pmid:19384566 |
| Ling Y et al. | A rapid and sensitive LC-MS/MS method for quantification of four anthocyanins and its application in a clinical pharmacology study of a bioadhesive black raspberry gel. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19896910 |
| Shan Q et al. | Purple sweet potato color ameliorates cognition deficits and attenuates oxidative damage and inflammation in aging mouse brain induced by d-galactose. | 2009 | J. Biomed. Biotechnol. | pmid:19865488 |
| Kay CD et al. | The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products. | 2009 | Mol Nutr Food Res | pmid:19415657 |
| Sutela S et al. | Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch. | 2009 | BMC Plant Biol. | pmid:19788757 |
| Auger B et al. | Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed. | 2009 | Planta | pmid:19760260 |
| Rubin G et al. | Members of the LBD family of transcription factors repress anthocyanin synthesis and affect additional nitrogen responses in Arabidopsis. | 2009 | Plant Cell | pmid:19933203 |
| Han SJ et al. | Metabolism of cyanidin-3-O-beta-D-glucoside isolated from black colored rice and its antiscratching behavioral effect in mice. | 2009 | J. Food Sci. | pmid:19799667 |
| Moraga AR et al. | Cloning and characterization of a glucosyltransferase from Crocus sativus stigmas involved in flavonoid glucosylation. | 2009 | BMC Plant Biol. | pmid:19695093 |
| Philpott M et al. | Dietary protection against free radicals: a case for multiple testing to establish structure-activity relationships for antioxidant potential of anthocyanic plant species. | 2009 | Int J Mol Sci | pmid:19399239 |
| Harding SA et al. | A comparative analysis of phenylpropanoid metabolism, N utilization, and carbon partitioning in fast- and slow-growing Populus hybrid clones. | 2009 | J. Exp. Bot. | pmid:19516073 |
| Cheng JC et al. | Detection of cyanidin in different-colored peanut testae and identification of peanut cyanidin 3-sambubioside. | 2009 | J. Agric. Food Chem. | pmid:19807153 |
| Nunn AV et al. | Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? | 2009 | Nutr Metab (Lond) | pmid:19371409 |
| Peel GJ et al. | The LAP1 MYB transcription factor orchestrates anthocyanidin biosynthesis and glycosylation in Medicago. | 2009 | Plant J. | pmid:19368693 |
| Gomez C et al. | Grapevine MATE-type proteins act as vacuolar H+-dependent acylated anthocyanin transporters. | 2009 | Plant Physiol. | pmid:19297587 |
| Ugalde CM et al. | Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers. | 2009 | Pharm. Res. | pmid:19137418 |
| Adisakwattana S et al. | alpha-Glucosidase inhibitory activity of cyanidin-3-galactoside and synergistic effect with acarbose. | 2009 | J Enzyme Inhib Med Chem | pmid:18615280 |
| Slavin M et al. | Antioxidant properties, phytochemical composition, and antiproliferative activity of Maryland-grown soybeans with colored seed coats. | 2009 | J. Agric. Food Chem. | pmid:19950996 |
| Slimestad R et al. | Analysis of phenolic compounds in six Norwegian plum cultivars (Prunus domestica L.). | 2009 | J. Agric. Food Chem. | pmid:19888727 |
| Qin C et al. | Separation and elucidation of anthocyanins in the fruit of mockstrawberry (Duchesnea indica Focke). | 2009 | Nat. Prod. Res. | pmid:19851924 |
| Yuan Y et al. | Transcriptional regulation of anthocyanin biosynthesis in red cabbage. | 2009 | Planta | pmid:19756724 |
| Shin DY et al. | Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723048 |
| Gargouri M et al. | Structure and epimerase activity of anthocyanidin reductase from Vitis vinifera. | 2009 | Acta Crystallogr. D Biol. Crystallogr. | pmid:19690377 |
| Modolo LV et al. | Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids. | 2009 | J. Mol. Biol. | pmid:19683002 |
| Felgines C et al. | Tissue distribution of anthocyanins in rats fed a blackberry anthocyanin-enriched diet. | 2009 | Mol Nutr Food Res | pmid:19653220 |
| Simões C et al. | Anthocyanin production in callus cultures of Cleome rosea: modulation by culture conditions and characterization of pigments by means of HPLC-DAD/ESIMS. | 2009 | Plant Physiol. Biochem. | pmid:19589687 |
| Butryee C et al. | Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf. | 2009 | Int J Food Sci Nutr | pmid:19572229 |
| Li JB et al. | A new acylated anthocyanin from the red flowers of Camellia hongkongensis and characterization of anthocyanins in the section Camellia species. | 2009 | J Integr Plant Biol | pmid:19522813 |
| Nakabayashi R et al. | Metabolomics-oriented isolation and structure elucidation of 37 compounds including two anthocyanins from Arabidopsis thaliana. | 2009 | Phytochemistry | pmid:19497599 |
| Jordheim M et al. | Acylated anthocyanins in inflorescence of spider flower (Cleome hassleriana). | 2009 | Phytochemistry | pmid:19427007 |
| Dreiseitel A et al. | Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B. | 2009 | Pharmacol. Res. | pmid:19416630 |
| Garzón GA et al. | Determination of anthocyanins, total phenolic content, and antioxidant activity in Andes Berry (Rubus glaucus Benth). | 2009 | J. Food Sci. | pmid:19397707 |
| Marczylo TH et al. | Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice. | 2009 | Cancer Chemother. Pharmacol. | pmid:19363608 |
| Kim SH et al. | Structural identification and antioxidant properties of major anthocyanin extracted from Omija (Schizandra chinensis) fruit. | 2009 | J. Food Sci. | pmid:19323727 |
| He J et al. | Stability of black raspberry anthocyanins in the digestive tract lumen and transport efficiency into gastric and small intestinal tissues in the rat. | 2009 | J. Agric. Food Chem. | pmid:19317488 |
| Osmani SA et al. | Effect of glucuronosylation on anthocyanin color stability. | 2009 | J. Agric. Food Chem. | pmid:19281238 |
| Dai J et al. | A comprehensive study of anthocyanin-containing extracts from selected blackberry cultivars: extraction methods, stability, anticancer properties and mechanisms. | 2009 | Food Chem. Toxicol. | pmid:19271318 |
| Mulabagal V et al. | Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. | 2009 | J. Agric. Food Chem. | pmid:19199585 |
| Pricelius S et al. | Substrate specificities of glycosidases from Aspergillus species pectinase preparations on elderberry anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19191672 |
| Kassim A et al. | Environmental and seasonal influences on red raspberry anthocyanin antioxidant contents and identification of quantitative traits loci (QTL). | 2009 | Mol Nutr Food Res | pmid:19156716 |
| Vasco C et al. | Phenolic compounds in Rosaceae fruits from Ecuador. | 2009 | J. Agric. Food Chem. | pmid:19143537 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
| Queiroz F et al. | Degradation of anthocyanins and anthocyanidins in blueberry jams/stuffed fish. | 2009 | J. Agric. Food Chem. | pmid:19845348 |
| Vasco C et al. | Chemical composition and phenolic compound profile of mortiño (Vaccinium floribundum Kunth). | 2009 | J. Agric. Food Chem. | pmid:19719139 |
| Dreiseitel A et al. | sPhospholipase A(2) is inhibited by anthocyanidins. | 2009 | J Neural Transm (Vienna) | pmid:19649692 |
| Montefiori M et al. | Characterization and quantification of anthocyanins in red kiwifruit ( Actinidia spp.). | 2009 | J. Agric. Food Chem. | pmid:19572542 |
| Matsunaga N et al. | Bilberry and its main constituents have neuroprotective effects against retinal neuronal damage in vitro and in vivo. | 2009 | Mol Nutr Food Res | pmid:19415665 |
| Thomasset S et al. | Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? | 2009 | Cancer Chemother. Pharmacol. | pmid:19294386 |
| Song W et al. | Phytochemical profiles of different mulberry (Morus sp.) species from China. | 2009 | J. Agric. Food Chem. | pmid:19761189 |
| Comeskey DJ et al. | Isolation and structural identification of the anthocyanin components of red kiwifruit. | 2009 | J. Agric. Food Chem. | pmid:19203266 |
| Bellido GG and Beta T | Anthocyanin composition and oxygen radical scavenging capacity (ORAC) of milled and pearled purple, black, and common barley. | 2009 | J. Agric. Food Chem. | pmid:19159302 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Knaup B et al. | Anthocyanins as lipoxygenase inhibitors. | 2009 | Mol Nutr Food Res | pmid:19072887 |
| Singh K et al. | Differential display mediated cloning of anthocyanidin reductase gene from tea (Camellia sinensis) and its relationship with the concentration of epicatechins. | 2009 | Tree Physiol. | pmid:19380395 |
| Garcia-Alonso M et al. | Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. | 2009 | J. Nutr. Biochem. | pmid:18789665 |
| Tanaka Y et al. | Recent progress of flower colour modification by biotechnology. | 2009 | Int J Mol Sci | pmid:20054474 |
| Sarr M et al. | In vitro vasorelaxation mechanisms of bioactive compounds extracted from Hibiscus sabdariffa on rat thoracic aorta. | 2009 | Nutr Metab (Lond) | pmid:19883513 |
| Albert NW et al. | Light-induced vegetative anthocyanin pigmentation in Petunia. | 2009 | J. Exp. Bot. | pmid:19380423 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Li L et al. | Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | 2009 | J. Agric. Food Chem. | pmid:19166352 |
| Matus JT et al. | Post-veraison sunlight exposure induces MYB-mediated transcriptional regulation of anthocyanin and flavonol synthesis in berry skins of Vitis vinifera. | 2009 | J. Exp. Bot. | pmid:19129169 |
| Kamiyama M et al. | Inhibition of low-density lipoprotein oxidation by Nagano purple grape (Vitis viniferaxVitis labrusca). | 2009 | J. Nutr. Sci. Vitaminol. | pmid:20086316 |
| Deluc LG et al. | Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay. | 2009 | BMC Genomics | pmid:19426499 |
| Lehtonen HM et al. | Urinary excretion of the main anthocyanin in lingonberry (Vaccinium vitis-idaea), cyanidin 3-O-galactoside, and its metabolites. | 2009 | J. Agric. Food Chem. | pmid:19351112 |
| Ban Y et al. | UDP-sugar biosynthetic pathway: contribution to cyanidin 3-galactoside biosynthesis in apple skin. | 2009 | Planta | pmid:19652996 |
| Lea MA et al. | Inhibition of growth and induction of differentiation of colon cancer cells by peach and plum phenolic compounds. | 2008 Jul-Aug | Anticancer Res. | pmid:18751377 |
| Fedenko VS | [Cyanidin as endogenous chelator of metal ions in maize seedling roots]. | 2008 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:18710034 |
| Kim JM et al. | Effects of black soybean [Glycine max (L.) Merr.] seed coats and its anthocyanidins on colonic inflammation and cell proliferation in vitro and in vivo. | 2008 | J. Agric. Food Chem. | pmid:18710248 |
| Li CY et al. | Corn husk as a potential source of anthocyanins. | 2008 | J. Agric. Food Chem. | pmid:19007127 |
| Mertens-Talcott SU et al. | Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. | 2008 | J. Agric. Food Chem. | pmid:18693743 |
| Meng L et al. | Antioxidant activities of polyphenols extracted from Perilla frutescens varieties. | 2008 | Molecules | pmid:19127243 |
| Lillo C et al. | Nutrient depletion as a key factor for manipulating gene expression and product formation in different branches of the flavonoid pathway. | 2008 | Plant Cell Environ. | pmid:18031469 |
| Kim MK et al. | Identification and quantification of anthocyanin pigments in colored rice. | 2008 | Nutr Res Pract | pmid:20126365 |
| Hassimotto NM et al. | Antioxidant status in humans after consumption of blackberry (Rubus fruticosus L.) juices with and without defatted milk. | 2008 | J. Agric. Food Chem. | pmid:19053224 |
| Li CY et al. | Gastroprotective effect of cyanidin 3-glucoside on ethanol-induced gastric lesions in rats. | 2008 | Alcohol | pmid:19038699 |
| De Rosso VV et al. | Singlet oxygen quenching by anthocyanin's flavylium cations. | 2008 | Free Radic. Res. | pmid:18985487 |
| Tarozzi A et al. | Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity. | 2008 | Neuroreport | pmid:18797302 |
| Lin LZ and Harnly JM | Phenolic compounds and chromatographic profiles of pear skins (Pyrus spp.). | 2008 | J. Agric. Food Chem. | pmid:18778075 |
| Zhou LL et al. | Development of tobacco callus cultures over expressing Arabidopsis PAP1/MYB75 transcription factor and characterization of anthocyanin biosynthesis. | 2008 | Planta | pmid:18766373 |
| Jensen GS et al. | In vitro and in vivo antioxidant and anti-inflammatory capacities of an antioxidant-rich fruit and berry juice blend. Results of a pilot and randomized, double-blinded, placebo-controlled, crossover study. | 2008 | J. Agric. Food Chem. | pmid:18717569 |
| Comandini P et al. | CZE separation of strawberry anthocyanins with acidic buffer and comparison with HPLC. | 2008 | J Sep Sci | pmid:18704996 |
| Felgines C et al. | Influence of glucose on cyanidin 3-glucoside absorption in rats. | 2008 | Mol Nutr Food Res | pmid:18646002 |
| Hollands W et al. | Urinary excretion of strawberry anthocyanins is dose dependent for physiological oral doses of fresh fruit. | 2008 | Mol Nutr Food Res | pmid:18645999 |
| Scalzo J et al. | The anthocyanin composition of different Vaccinium, Ribes and Rubus genotypes. | 2008 | Biofactors | pmid:19706968 |
| Matsuura R et al. | Determination of antioxidant activity and characterization of antioxidant phenolics in the plum vinegar extract of cherry blossom (Prunus lannesiana). | 2008 | J. Agric. Food Chem. | pmid:18092753 |
| Yan Y et al. | High-yield anthocyanin biosynthesis in engineered Escherichia coli. | 2008 | Biotechnol. Bioeng. | pmid:18023053 |
| Nicoletti I et al. | Identification and quantification of phenolic compounds in grapes by HPLC-PDA-ESI-MS on a semimicro separation scale. | 2008 | J. Agric. Food Chem. | pmid:18781764 |
| Zhang J et al. | Determination of anthocyanins and exploration of relationship between their composition and petal coloration in crape myrtle (Lagerstroemia hybrid). | 2008 | J Integr Plant Biol | pmid:18713426 |
| Min K and Ebeler SE | Flavonoid effects on DNA oxidation at low concentrations relevant to physiological levels. | 2008 | Food Chem. Toxicol. | pmid:17707569 |
| Griesser M et al. | Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle. | 2008 | J. Exp. Bot. | pmid:18487633 |
| Park MY et al. | Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin. | 2008 | Nutr Res Pract | pmid:20126360 |
| Park JS et al. | Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa). | 2008 | Plant Cell Rep. | pmid:18317777 |