Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mutwil M et al. | PlaNet: combined sequence and expression comparisons across plant networks derived from seven species. | 2011 | Plant Cell | pmid:21441431 |
| Jing Yu V et al. | Identification of components of grape powder with anti-apoptotic effects. | 2011 | Toxicol Ind Health | pmid:20699283 |
| Yao JW et al. | Affinity interactions between natural pigments and human whole saliva. | 2011 | Arch. Oral Biol. | pmid:21112045 |
| Paixão J et al. | Dietary anthocyanins protect endothelial cells against peroxynitrite-induced mitochondrial apoptosis pathway and Bax nuclear translocation: an in vitro approach. | 2011 | Apoptosis | pmid:21785847 |
| Woodward GM et al. | Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation. | 2011 | Mol Nutr Food Res | pmid:21370450 |
| Shrestha B et al. | In situ cell-by-cell imaging and analysis of small cell populations by mass spectrometry. | 2011 | Anal. Chem. | pmid:21388149 |
| Mallery SR et al. | Effects of human oral mucosal tissue, saliva, and oral microflora on intraoral metabolism and bioactivation of black raspberry anthocyanins. | 2011 | Cancer Prev Res (Phila) | pmid:21558412 |
| Zhang Q et al. | A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3',5'-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans. | 2011 | Chem. Commun. (Camb.) | pmid:21892498 |
| Kanamoto Y et al. | A black soybean seed coat extract prevents obesity and glucose intolerance by up-regulating uncoupling proteins and down-regulating inflammatory cytokines in high-fat diet-fed mice. | 2011 | J. Agric. Food Chem. | pmid:21751816 |
| Woodward GM et al. | Anthocyanins remain stable during commercial blackcurrant juice processing. | 2011 | J. Food Sci. | pmid:21729077 |
| Min J et al. | Neuroprotective effect of cyanidin-3-O-glucoside anthocyanin in mice with focal cerebral ischemia. | 2011 | Neurosci. Lett. | pmid:21651957 |
| Ben-Simhon Z et al. | A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development. | 2011 | Planta | pmid:21643990 |
| Cuevas Montilla E et al. | Soluble and bound phenolic compounds in different Bolivian purple corn ( Zea mays L.) cultivars. | 2011 | J. Agric. Food Chem. | pmid:21639140 |
| Jordheim M et al. | Identification of cyanidin 3-O-β-(6″-(3-hydroxy-3-methylglutaroyl)glucoside) and other anthocyanins from wild and cultivated blackberries. | 2011 | J. Agric. Food Chem. | pmid:21635009 |
| Abdel-Moemin AR | Switching to black rice diets modulates low-density lipoprotein oxidation and lipid measurements in rabbits. | 2011 | Am. J. Med. Sci. | pmid:21289511 |
| Rababah TM et al. | Effect of jam processing and storage on total phenolics, antioxidant activity, and anthocyanins of different fruits. | 2011 | J. Sci. Food Agric. | pmid:21254073 |
| Tanaka J et al. | Purple rice extract and anthocyanidins of the constituents protect against light-induced retinal damage in vitro and in vivo. | 2011 | J. Agric. Food Chem. | pmid:21175193 |
| Zhao J et al. | MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. | 2011 | Plant Cell | pmid:21467581 |
| Mewis I et al. | Specific poly-phenolic compounds in cell culture of Vitis vinifera L. cv. Gamay Fréaux. | 2011 | Appl. Biochem. Biotechnol. | pmid:21061087 |
| Liu Y et al. | Comparative study of phenolic compounds and antioxidant activity in different species of cherries. | 2011 | J. Food Sci. | pmid:22417346 |
| Andrade JM et al. | Phenolic composition in different genotypes of Guabiju fruits (Myrcianthes pungens) and their potential as antioxidant and antichemotactic agents. | 2011 | J. Food Sci. | pmid:22417582 |
| Stalmach A et al. | Identification of (poly)phenolic compounds in concord grape juice and their metabolites in human plasma and urine after juice consumption. | 2011 | J. Agric. Food Chem. | pmid:21812481 |
| Xu C et al. | Influence of growing season on phenolic compounds and antioxidant properties of grape berries from vines grown in subtropical climate. | 2011 | J. Agric. Food Chem. | pmid:21235208 |
| Pinho C et al. | Optimization of conditions for anthocyanin hydrolysis from red wine using response surface methodology (RSM). | 2011 | J. Agric. Food Chem. | pmid:21158431 |
| You Q et al. | Inhibitory effects of muscadine anthocyanins on α-glucosidase and pancreatic lipase activities. | 2011 | J. Agric. Food Chem. | pmid:21797278 |
| Kumar D et al. | A review on chemical and biological properties of Cayratia trifolia Linn. (Vitaceae). | 2011 | Pharmacogn Rev | pmid:22279376 |
| Fournier-Level A et al. | Genetic mechanisms underlying the methylation level of anthocyanins in grape (Vitis vinifera L.). | 2011 | BMC Plant Biol. | pmid:22171701 |
| Gillman JD et al. | Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in brown hilum and brown seed coats. | 2011 | BMC Plant Biol. | pmid:22070454 |
| Yamaura K et al. | Anthocyanins from bilberry (Vaccinium myrtillus L.) alleviate pruritus in a mouse model of chronic allergic contact dermatitis. | 2011 | Pharmacognosy Res | pmid:22022165 |
| Mazzio EA et al. | The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | 2011 | Int J Mol Sci | pmid:21340000 |
| Suzuki R et al. | Anthocyanidins-enriched bilberry extracts inhibit 3T3-L1 adipocyte differentiation via the insulin pathway. | 2011 | Nutr Metab (Lond) | pmid:21385419 |
| Kortstee AJ et al. | Anthocyanin production as a potential visual selection marker during plant transformation. | 2011 | Transgenic Res. | pmid:21340526 |
| Sharma M et al. | Identification of the pr1 gene product completes the anthocyanin biosynthesis pathway of maize. | 2011 | Genetics | pmid:21385724 |
| Maldonado-Rojas W and Olivero-Verbel J | Potential interaction of natural dietary bioactive compounds with COX-2. | 2011 | J. Mol. Graph. Model. | pmid:21803623 |
| Fortes AM et al. | Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening. | 2011 | BMC Plant Biol. | pmid:22047180 |
| Horbowicz M et al. | Effects of methyl jasmonate on accumulation of flavonoids in seedlings of common buckwheat (Fagopyrum esculentum Moench). | 2011 | Acta. Biol. Hung. | pmid:21840829 |
| Choi JG et al. | In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. | 2011 | Evid Based Complement Alternat Med | pmid:19687188 |
| Massaad CA | Neuronal and vascular oxidative stress in Alzheimer's disease. | 2011 | Curr Neuropharmacol | pmid:22654724 |
| Korać RR and Khambholja KM | Potential of herbs in skin protection from ultraviolet radiation. | 2011 | Pharmacogn Rev | pmid:22279374 |
| Kwon SC and Kim YB | Antioxidative and aldose reductase-inhibitory effects of a fermentation filtrate of Rubus coreanus. | 2011 | Lab Anim Res | pmid:22232649 |
| Panickar KS and Anderson RA | Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. | 2011 | Int J Mol Sci | pmid:22174658 |
| Abidi W et al. | Evaluation of antioxidant compounds and total sugar content in a nectarine [Prunus persica (L.) Batsch] progeny. | 2011 | Int J Mol Sci | pmid:22072927 |
| Alvarez-Suarez JM et al. | Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase. | 2011 | PLoS ONE | pmid:22016781 |
| Wu X et al. | Optimization of phenolic antioxidant extraction from Wuweizi (Schisandra chinensis) pulp using random-centroid optimazation methodology. | 2011 | Int J Mol Sci | pmid:22016656 |
| Lin LZ et al. | UHPLC-PDA-ESI/HRMS/MS(n) analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard greens (Brassica juncea Coss variety). | 2011 | J. Agric. Food Chem. | pmid:21970730 |
| Wei YZ et al. | Differential expression of anthocyanin biosynthetic genes in relation to anthocyanin accumulation in the pericarp of Litchi chinensis Sonn. | 2011 | PLoS ONE | pmid:21559331 |
| Wei SD et al. | Antioxidant activities of fractions of polymeric procyanidins from stem bark of Acacia confusa. | 2011 | Int J Mol Sci | pmid:21541049 |
| Gou JY et al. | Negative regulation of anthocyanin biosynthesis in Arabidopsis by a miR156-targeted SPL transcription factor. | 2011 | Plant Cell | pmid:21487097 |
| Feng Y et al. | A three-component gene expression system and its application for inducible flavonoid overproduction in transgenic Arabidopsis thaliana. | 2011 | PLoS ONE | pmid:21408135 |
| Akkarachiyasit S et al. | In vitro inhibitory effects of cyandin-3-rutinoside on pancreatic α-amylase and its combined effect with acarbose. | 2011 | Molecules | pmid:21368719 |