Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Khandelwal VK et al. | Hemidesmus indicus and Hibiscus rosa-sinensis Affect Ischemia Reperfusion Injury in Isolated Rat Hearts. | 2011 | Evid Based Complement Alternat Med | pmid:20953394 |
| Jing Yu V et al. | Identification of components of grape powder with anti-apoptotic effects. | 2011 | Toxicol Ind Health | pmid:20699283 |
| Yao JW et al. | Affinity interactions between natural pigments and human whole saliva. | 2011 | Arch. Oral Biol. | pmid:21112045 |
| Woodward GM et al. | Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation. | 2011 | Mol Nutr Food Res | pmid:21370450 |
| Shrestha B et al. | In situ cell-by-cell imaging and analysis of small cell populations by mass spectrometry. | 2011 | Anal. Chem. | pmid:21388149 |
| Mallery SR et al. | Effects of human oral mucosal tissue, saliva, and oral microflora on intraoral metabolism and bioactivation of black raspberry anthocyanins. | 2011 | Cancer Prev Res (Phila) | pmid:21558412 |
| Nishizaki Y et al. | Structure of the acyl-glucose-dependent anthocyanin 5-O-glucosyltransferase gene in carnations and its disruption by transposable elements in some varieties. | 2011 | Mol. Genet. Genomics | pmid:22048706 |
| Song J et al. | Determination of cyanidin-3-glucoside (red kernel food colour) in beverages by high performance liquid chromatography and a study of its degradation by quadruple time-of-flight mass spectrometry. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:22014114 |
| Zhang Q et al. | A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3',5'-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans. | 2011 | Chem. Commun. (Camb.) | pmid:21892498 |
| Jin Y et al. | A randomised trial to investigate the effects of acute consumption of a blackcurrant juice drink on markers of vascular reactivity and bioavailability of anthocyanins in human subjects. | 2011 | Eur J Clin Nutr | pmid:21540876 |
| El Babili F et al. | Oregano: chemical analysis and evaluation of its antimalarial, antioxidant, and cytotoxic activities. | 2011 | J. Food Sci. | pmid:21535822 |
| Santos J et al. | Inhibition of host- and bacteria-derived proteinases by natural anthocyanins. | 2011 | J. Periodont. Res. | pmid:21517858 |
| Lin LZ et al. | LC-PDA-ESI/MS(n) identification of new anthocyanins in purple Bordeaux radish ( Raphanus sativus L. variety). | 2011 | J. Agric. Food Chem. | pmid:21513350 |
| Lim TG et al. | Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity. | 2011 | Biochem. Pharmacol. | pmid:21501596 |
| Reichel M et al. | Changes in flavonoids and nonphenolic pigments during on-tree maturation and postharvest pericarp browning of litchi (Litchi chinensis Sonn.) as shown by HPLC-MSn. | 2011 | J. Agric. Food Chem. | pmid:21413696 |
| Reber JD et al. | Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries. | 2011 | Int J Food Sci Nutr | pmid:21385007 |
| Montilla EC et al. | Anthocyanin composition of black carrot (Daucus carota ssp. sativus var. atrorubens Alef.) cultivars Antonina, Beta Sweet, Deep Purple, and Purple Haze. | 2011 | J. Agric. Food Chem. | pmid:21381748 |
| Wei X et al. | Cyanidin-3-O-β-glucoside improves obesity and triglyceride metabolism in KK-Ay mice by regulating lipoprotein lipase activity. | 2011 | J. Sci. Food Agric. | pmid:21360538 |
| Liu Y et al. | Comparative study of phenolic compounds and antioxidant activity in different species of cherries. | 2011 | J. Food Sci. | pmid:22417346 |
| Saito N et al. | The blue anthocyanin pigments from the blue flowers of Heliophila coronopifolia L. (Brassicaceae). | 2011 | Phytochemistry | pmid:21903230 |
| Andrade JM et al. | Phenolic composition in different genotypes of Guabiju fruits (Myrcianthes pungens) and their potential as antioxidant and antichemotactic agents. | 2011 | J. Food Sci. | pmid:22417582 |
| Vanzo A et al. | Exceptionally fast uptake and metabolism of cyanidin 3-glucoside by rat kidneys and liver. | 2011 | J. Nat. Prod. | pmid:21510696 |
| Lätti AK et al. | Phenolic compounds in berries and flowers of a natural hybrid between bilberry and lingonberry (Vaccinium × intermedium Ruthe). | 2011 | Phytochemistry | pmid:21382629 |
| Kyselova Z | Toxicological aspects of the use of phenolic compounds in disease prevention. | 2011 | Interdiscip Toxicol | pmid:22319251 |
| Kumar D et al. | A review on chemical and biological properties of Cayratia trifolia Linn. (Vitaceae). | 2011 | Pharmacogn Rev | pmid:22279376 |
| Fournier-Level A et al. | Genetic mechanisms underlying the methylation level of anthocyanins in grape (Vitis vinifera L.). | 2011 | BMC Plant Biol. | pmid:22171701 |
| Adisakwattana S et al. | Cyanidin-3-rutinoside alleviates postprandial hyperglycemia and its synergism with acarbose by inhibition of intestinal α-glucosidase. | 2011 | J Clin Biochem Nutr | pmid:21765605 |
| Shimazaki M et al. | Pink-colored grape berry is the result of short insertion in intron of color regulatory gene. | 2011 | PLoS ONE | pmid:21695059 |
| Martin C et al. | How can research on plants contribute to promoting human health? | 2011 | Plant Cell | pmid:21586682 |
| Liang Z et al. | CIELAB coordinates in response to berry skin anthocyanins and their composition in Vitis. | 2011 | J. Food Sci. | pmid:21535819 |
| Wang SC et al. | Aqueous Extract from Hibiscus sabdariffa Linnaeus Ameliorate Diabetic Nephropathy via Regulating Oxidative Status and Akt/Bad/14-3-3γ in an Experimental Animal Model. | 2011 | Evid Based Complement Alternat Med | pmid:19965962 |
| Kayodé AP et al. | Uncommonly high levels of 3-deoxyanthocyanidins and antioxidant capacity in the leaf sheaths of dye sorghum. | 2011 | J. Agric. Food Chem. | pmid:21322653 |
| Massaad CA | Neuronal and vascular oxidative stress in Alzheimer's disease. | 2011 | Curr Neuropharmacol | pmid:22654724 |
| Bhuiyan MI et al. | The Neuroprotective Potential of Cyanidin-3-glucoside Fraction Extracted from Mulberry Following Oxygen-glucose Deprivation. | 2011 | Korean J. Physiol. Pharmacol. | pmid:22359473 |
| Devi PS et al. | Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7). | 2011 | Int J Breast Cancer | pmid:22312562 |
| Korać RR and Khambholja KM | Potential of herbs in skin protection from ultraviolet radiation. | 2011 | Pharmacogn Rev | pmid:22279374 |
| Kwon SC and Kim YB | Antioxidative and aldose reductase-inhibitory effects of a fermentation filtrate of Rubus coreanus. | 2011 | Lab Anim Res | pmid:22232649 |
| Panickar KS and Anderson RA | Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. | 2011 | Int J Mol Sci | pmid:22174658 |
| Ohno S et al. | A bHLH transcription factor, DvIVS, is involved in regulation of anthocyanin synthesis in dahlia (Dahlia variabilis). | 2011 | J. Exp. Bot. | pmid:21765172 |
| Zou TB et al. | Optimization of ultrasound-assisted extraction of anthocyanins from mulberry, using response surface methodology. | 2011 | Int J Mol Sci | pmid:21686165 |
| Ke Z et al. | Cyanidin-3-glucoside ameliorates ethanol neurotoxicity in the developing brain. | 2011 | J. Neurosci. Res. | pmid:21671257 |
| Rajbhandari R et al. | Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. | 2011 | J. Agric. Food Chem. | pmid:21634376 |
| Kim KT et al. | Neuroprotective effect of anthocyanin on experimental traumatic spinal cord injury. | 2011 | J Korean Neurosurg Soc | pmid:21607177 |
| Telias A et al. | Apple skin patterning is associated with differential expression of MYB10. | 2011 | BMC Plant Biol. | pmid:21599973 |
| Huang SS et al. | Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice. | 2011 | Evid Based Complement Alternat Med | pmid:21584194 |
| Udani JK et al. | Effects of Açai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. | 2011 | Nutr J | pmid:21569436 |
| Wei YZ et al. | Differential expression of anthocyanin biosynthetic genes in relation to anthocyanin accumulation in the pericarp of Litchi chinensis Sonn. | 2011 | PLoS ONE | pmid:21559331 |
| Yang H et al. | Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. | 2011 | J. Agric. Food Chem. | pmid:21302942 |
| Wei SD et al. | Antioxidant activities of fractions of polymeric procyanidins from stem bark of Acacia confusa. | 2011 | Int J Mol Sci | pmid:21541049 |
| Gou JY et al. | Negative regulation of anthocyanin biosynthesis in Arabidopsis by a miR156-targeted SPL transcription factor. | 2011 | Plant Cell | pmid:21487097 |