Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shrestha B et al. | In situ cell-by-cell imaging and analysis of small cell populations by mass spectrometry. | 2011 | Anal. Chem. | pmid:21388149 |
| Pinho C et al. | Optimization of conditions for anthocyanin hydrolysis from red wine using response surface methodology (RSM). | 2011 | J. Agric. Food Chem. | pmid:21158431 |
| Suzuki R et al. | Anthocyanidins-enriched bilberry extracts inhibit 3T3-L1 adipocyte differentiation via the insulin pathway. | 2011 | Nutr Metab (Lond) | pmid:21385419 |
| Qaâdan F et al. | Polyphenols from Ginkgo biloba. | 2010 Oct-Dec | Sci Pharm | pmid:21179324 |
| Liu X et al. | Preparative separation and enrichment of syringopicroside from Folium syringae leaves with macroporous resins. | 2010 | J. Biomed. Biotechnol. | pmid:21234415 |
| Xu M et al. | Cyanidin-3-glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2. | 2010 | Mol. Cancer | pmid:21034468 |
| Ozgen M et al. | Total phenolic, anthocyanin contents and antioxidant capacity of selected elderberry (Sambucus canadensis L.) accessions. | 2010 | Pharmacogn Mag | pmid:20931079 |
| D'Archivio M et al. | Bioavailability of the polyphenols: status and controversies. | 2010 | Int J Mol Sci | pmid:20480022 |
| Kuehl KS et al. | Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial. | 2010 | J Int Soc Sports Nutr | pmid:20459662 |
| Wei S et al. | Concentration of rutin model solutions from their mixtures with glucose using ultrafiltration. | 2010 | Int J Mol Sci | pmid:20386660 |
| Han Y et al. | Ectopic expression of apple F3'H genes contributes to anthocyanin accumulation in the Arabidopsis tt7 mutant grown under nitrogen stress. | 2010 | Plant Physiol. | pmid:20357139 |
| Deguchi Y and Miyazaki K | Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract. | 2010 | Nutr Metab (Lond) | pmid:20181067 |
| Pourcel L et al. | The formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and implications for the sequestration of anthocyanin pigments. | 2010 | Mol Plant | pmid:20085894 |
| Sahay A and Shakya M | Structure prediction of dihydroflavonol 4- reductase and anthocyanidin synthase from spinach. | 2010 | Bioinformation | pmid:21364828 |
| Halbwirth H | The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. | 2010 | Int J Mol Sci | pmid:20386656 |
| Ernst IM et al. | Cellular uptake, stability, visualization by 'Naturstoff reagent A', and multidrug resistance protein 1 gene-regulatory activity of cyanidin in human keratinocytes. | 2010 | Pharmacol. Res. | pmid:19897037 |
| Ojeda D et al. | Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa. | 2010 | J Ethnopharmacol | pmid:19808084 |
| Solomon A et al. | Protection of fibroblasts (NIH-3T3) against oxidative damage by cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). | 2010 | J. Agric. Food Chem. | pmid:20443626 |
| Shi MZ and Xie DY | Features of anthocyanin biosynthesis in pap1-D and wild-type Arabidopsis thaliana plants grown in different light intensity and culture media conditions. | 2010 | Planta | pmid:20309578 |
| Choi MJ et al. | Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system. | 2010 | Biol. Pharm. Bull. | pmid:20190403 |
| Kim JE et al. | Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. | 2010 | Biochem. Pharmacol. | pmid:20096264 |
| Sparzak B et al. | HPLC analysis of polyphenols in the fruits of Rubus idaeus L. (Rosaceae). | 2010 | Nat. Prod. Res. | pmid:21104526 |
| Josuttis M et al. | Solar UVB response of bioactives in strawberry (Fragaria × ananassa Duch. L.): a comparison of protected and open-field cultivation. | 2010 | J. Agric. Food Chem. | pmid:21086998 |
| Speciale A et al. | Cyanidin-3-O-glucoside protection against TNF-α-induced endothelial dysfunction: involvement of nuclear factor-κB signaling. | 2010 | J. Agric. Food Chem. | pmid:20958056 |
| Sentandreu E et al. | LC-DAD-ESI/MS(n) determination of direct condensation flavanol-anthocyanin adducts in pressure extracted pomegranate (Punica granatum L.) juice. | 2010 | J. Agric. Food Chem. | pmid:20839870 |
| Gill CI et al. | Profiling of phenols in human fecal water after raspberry supplementation. | 2010 | J. Agric. Food Chem. | pmid:20809621 |
| Salvatierra A et al. | Comparison of transcriptional profiles of flavonoid genes and anthocyanin contents during fruit development of two botanical forms of Fragaria chiloensis ssp. chiloensis. | 2010 | Phytochemistry | pmid:20800857 |
| Montilla EC et al. | Preparative isolation of anthocyanins from Japanese purple sweet potato (Ipomoea batatas L.) varieties by high-speed countercurrent chromatography. | 2010 | J. Agric. Food Chem. | pmid:20731350 |
| Andersen ØM et al. | Anthocyanins with unusual furanose sugar (apiose) from leaves of Synadenium grantii (Euphorbiaceae). | 2010 | Phytochemistry | pmid:20594565 |
| Zhu F et al. | Anthocyanins, hydroxycinnamic acid derivatives, and antioxidant activity in roots of different chinese purple-fleshed sweetpotato genotypes. | 2010 | J. Agric. Food Chem. | pmid:20524661 |
| Cuevas-RodrÃguez EO et al. | Characterization of anthocyanins and proanthocyanidins in wild and domesticated Mexican blackberries (Rubus spp.). | 2010 | J. Agric. Food Chem. | pmid:20507066 |
| Li X et al. | Purple canola: Arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. | 2010 | J. Agric. Food Chem. | pmid:20073469 |
| White BL et al. | Proximate and polyphenolic characterization of cranberry pomace. | 2010 | J. Agric. Food Chem. | pmid:20020689 |
| Truong VD et al. | Characterization of anthocyanins and anthocyanidins in purple-fleshed sweetpotatoes by HPLC-DAD/ESI-MS/MS. | 2010 | J. Agric. Food Chem. | pmid:20017481 |
| Chakraborty M et al. | Effect of the novel radiant zone drying method on anthocyanins and phenolics of three blueberry liquids. | 2010 | J. Agric. Food Chem. | pmid:19954224 |
| Zu XY et al. | Anthocyanins extracted from Chinese blueberry (Vaccinium uliginosum L.) and its anticancer effects on DLD-1 and COLO205 cells. | 2010 | Chin. Med. J. | pmid:21034658 |
| Sreerama YN et al. | Variability in the distribution of phenolic compounds in milled fractions of chickpea and horse gram: evaluation of their antioxidant properties. | 2010 | J. Agric. Food Chem. | pmid:20593828 |
| Lätti AK et al. | Anthocyanin and flavonol variation in bog bilberries (Vaccinium uliginosum L.) in Finland. | 2010 | J. Agric. Food Chem. | pmid:20000402 |
| Deng J et al. | Comparative study on iron release from soybean (Glycine max) seed ferritin induced by anthocyanins and ascorbate. | 2010 | J. Agric. Food Chem. | pmid:19921836 |
| Takasawa R et al. | Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. | 2010 | Bioorg. Med. Chem. | pmid:20801663 |
| Kuhn I et al. | Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. | 2010 | Bioorg. Med. Chem. | pmid:20951593 |
| Lopes-Lutz D et al. | Characterization and quantification of polyphenols in Amazon grape (Pourouma cecropiifolia Martius). | 2010 | Molecules | pmid:21116224 |
| Okazaki Y et al. | A beverage containing fermented black soybean ameliorates ferric nitrilotriacetate-induced renal oxidative damage in rats. | 2010 | J Clin Biochem Nutr | pmid:21103028 |
| Falginella L et al. | Expansion and subfunctionalisation of flavonoid 3',5'-hydroxylases in the grapevine lineage. | 2010 | BMC Genomics | pmid:20939908 |
| Sasaki K et al. | Functional divergence within class B MADS-box genes TfGLO and TfDEF in Torenia fournieri Lind. | 2010 | Mol. Genet. Genomics | pmid:20872230 |
| Treutter D | Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. | 2010 | Int J Mol Sci | pmid:20479987 |
| Kovinich N et al. | Functional characterization of a UDP-glucose:flavonoid 3-O-glucosyltransferase from the seed coat of black soybean (Glycine max (L.) Merr.). | 2010 | Phytochemistry | pmid:20621794 |
| Stushnoff C et al. | Flavonoid profiling and transcriptome analysis reveals new gene-metabolite correlations in tubers of Solanum tuberosum L. | 2010 | J. Exp. Bot. | pmid:20110266 |
| Suttana W et al. | Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. | 2010 | Mol. Cancer | pmid:20438634 |
| Fortalezas S et al. | Antioxidant properties and neuroprotective capacity of strawberry tree fruit (Arbutus unedo). | 2010 | Nutrients | pmid:22254017 |