Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Marinova K et al. | The Arabidopsis MATE transporter TT12 acts as a vacuolar flavonoid/H+ -antiporter active in proanthocyanidin-accumulating cells of the seed coat. | 2007 | Plant Cell | pmid:17601828 |
| Ayaz E and Alpsoy HC | [Garlic (Allium sativum) and traditional medicine]. | 2007 | Turkiye Parazitol Derg | pmid:17594659 |
| Coates EM et al. | Colon-available raspberry polyphenols exhibit anti-cancer effects on in vitro models of colon cancer. | 2007 | J Carcinog | pmid:17442116 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Feng R et al. | Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. | 2007 | J. Biol. Chem. | pmid:17360708 |
| D'Auria JC et al. | Identification and characterization of the BAHD acyltransferase malonyl CoA: anthocyanidin 5-O-glucoside-6''-O-malonyltransferase (At5MAT) in Arabidopsis thaliana. | 2007 | FEBS Lett. | pmid:17292360 |
| Liu L et al. | Degradation of cyanidin 3-rutinoside in the presence of (-)-epicatechin and litchi pericarp polyphenol oxidase. | 2007 | J. Agric. Food Chem. | pmid:17914871 |
| Sasaki R et al. | Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice. | 2007 | Biochem. Pharmacol. | pmid:17869225 |
| Mulabagal V et al. | Cultivars of apple fruits that are not marketed with potential for anthocyanin production. | 2007 | J. Agric. Food Chem. | pmid:17822290 |
| Esparza I et al. | Complexing capacity profiles of naturally occurring ligands in Tempranillo wines for Cu and Zn: an electroanalytical approach for cupric casse. | 2007 | Anal. Chim. Acta | pmid:17765065 |
| Kim SJ et al. | Identification of anthocyanins in the sprouts of buckwheat. | 2007 | J. Agric. Food Chem. | pmid:17580874 |
| de Brito ES et al. | Anthocyanins present in selected tropical fruits: acerola, jambolão, jussara, and guajiru. | 2007 | J. Agric. Food Chem. | pmid:17929888 |
| Yao Y and Vieira A | Protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity. | 2007 | Neurotoxicology | pmid:16956663 |
| Kern M et al. | Limited stability in cell culture medium and hydrogen peroxide formation affect the growth inhibitory properties of delphinidin and its degradation product gallic acid. | 2007 | Mol Nutr Food Res | pmid:17729219 |
| Fujihara T et al. | High-molecular-weight polyphenols from oolong tea and black tea: purification, some properties, and role in increasing mitochondrial membrane potential. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17341825 |
| Cortell JM et al. | Influence of vine vigor on grape (Vitis vinifera L. Cv. Pinot Noir) anthocyanins. 2. Anthocyanins and pigmented polymers in wine. | 2007 | J. Agric. Food Chem. | pmid:17636934 |
| Cortell JM et al. | Influence of vine vigor on grape (Vitis vinifera L. Cv. Pinot Noir) anthocyanins. 1. Anthocyanin concentration and composition in fruit. | 2007 | J. Agric. Food Chem. | pmid:17636933 |
| Jordheim M et al. | Anthocyanins in berries of ribes including gooseberry cultivars with a high content of acylated pigments. | 2007 | J. Agric. Food Chem. | pmid:17579440 |
| Lans C et al. | Ethnoveterinary medicines used for ruminants in British Columbia, Canada. | 2007 | J Ethnobiol Ethnomed | pmid:17324258 |
| Castellarin SD and Di Gaspero G | Transcriptional control of anthocyanin biosynthetic genes in extreme phenotypes for berry pigmentation of naturally occurring grapevines. | 2007 | BMC Plant Biol. | pmid:17760970 |
| Grimplet J et al. | Tissue-specific mRNA expression profiling in grape berry tissues. | 2007 | BMC Genomics | pmid:17584945 |
| Cassinese C et al. | New liquid chromatography method with ultraviolet detection for analysis of anthocyanins and anthocyanidins in Vaccinium myrtillus fruit dry extracts and commercial preparations. | 2007 Jul-Aug | J AOAC Int | pmid:17760327 |
| Fedenko VS | [Dose effect of cyanidin interaction with lead ions in roots of maize seedlings]. | 2007 Mar-Apr | Ukr Biokhim Zh (1999) | pmid:18030746 |
| Laitinen RA et al. | Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida. | 2008 | J. Exp. Bot. | pmid:18725377 |
| Conn S et al. | Purification, molecular cloning, and characterization of glutathione S-transferases (GSTs) from pigmented Vitis vinifera L. cell suspension cultures as putative anthocyanin transport proteins. | 2008 | J. Exp. Bot. | pmid:18836188 |
| Osmani SA et al. | Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. | 2008 | Plant Physiol. | pmid:18829982 |
| Gastrointestinal pharmacology. | 2008 | Indian J Pharmacol | pmid:21593966 | |
| Merzlyak MN et al. | Light absorption by anthocyanins in juvenile, stressed, and senescing leaves. | 2008 | J. Exp. Bot. | pmid:18796701 |
| Xu F et al. | Molecular cloning and function analysis of an anthocyanidin synthase gene from Ginkgo biloba, and its expression in abiotic stress responses. | 2008 | Mol. Cells | pmid:18779661 |
| Zhang G et al. | Structure-dependent photodegradation of carotenoids accelerated by dimethyl tetrasulfide under UVA irradiation. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18685214 |
| Steigerwalt RD et al. | Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects. | 2008 | Mol. Vis. | pmid:18618008 |
| Fukamachi K et al. | Purple corn color suppresses Ras protein level and inhibits 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in the rat. | 2008 | Cancer Sci. | pmid:18616524 |
| Dancs G et al. | The effects of enhanced methionine synthesis on amino acid and anthocyanin content of potato tubers. | 2008 | BMC Plant Biol. | pmid:18549488 |
| Saito N et al. | Tetra-acylated cyanidin 3-sophoroside-5-glucosides from the flowers of Iberis umbellata L. (Cruciferae). | 2008 | Phytochemistry | pmid:18514755 |
| Hattori M et al. | Different inhibitory response of cyanidin and methylene blue for filament formation of tau microtubule-binding domain. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18619417 |
| Meng S et al. | Natural dyes adsorbed on TiO2 nanowire for photovoltaic applications: enhanced light absorption and ultrafast electron injection. | 2008 | Nano Lett. | pmid:18788788 |
| Hassimotto NM et al. | Absorption and metabolism of cyanidin-3-glucoside and cyanidin-3-rutinoside extracted from wild mulberry (Morus nigra L.) in rats. | 2008 | Nutr Res | pmid:19083408 |
| Kohyama N et al. | Changes in anthocyanins in the grains of purple waxy hull-less barley during seed maturation and after harvest. | 2008 | J. Agric. Food Chem. | pmid:18558760 |
| Li JB et al. | Anthocyanins from red flowers of Camellia cultivar 'Dalicha'. | 2008 | Phytochemistry | pmid:18466934 |
| Pawlowska AM et al. | Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits. | 2008 | J. Agric. Food Chem. | pmid:18412362 |
| Sakaguchi Y et al. | Major anthocyanins from purple asparagus (Asparagus officinalis). | 2008 | Phytochemistry | pmid:18406435 |
| Li Volti G et al. | Anesthetics and natural heme oxygenase-1 inducers: waiting for carbon monoxide? | 2008 | Ann. Surg. | pmid:18362637 |
| Tulio AZ et al. | Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry. | 2008 | J. Agric. Food Chem. | pmid:18290621 |
| Guo H et al. | Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-alpha-induced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation. | 2008 | Biochem. Pharmacol. | pmid:18179781 |
| Ku CS and Mun SP | Optimization of the extraction of anthocyanin from Bokbunja (Rubus coreanus Miq.) marc produced during traditional wine processing and characterization of the extracts. | 2008 | Bioresour. Technol. | pmid:18456493 |
| Wang CY et al. | Increasing antioxidant activity and reducing decay of blueberries by essential oils. | 2008 | J. Agric. Food Chem. | pmid:18442248 |
| Nakatsuka T et al. | Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian. | 2008 | J. Exp. Bot. | pmid:18375606 |
| Maruyama C et al. | Azuki bean juice lowers serum triglyceride concentrations in healthy young women. | 2008 | J Clin Biochem Nutr | pmid:18648655 |
| Jugdé H et al. | Isolation and characterization of a novel glycosyltransferase that converts phloretin to phlorizin, a potent antioxidant in apple. | 2008 | FEBS J. | pmid:18573104 |
| Dani C et al. | Protective effects of purple grape juice on carbon tetrachloride-induced oxidative stress in brains of adult Wistar rats. | 2008 | J Med Food | pmid:18361738 |