Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stintzing FC et al. | Color and antioxidant properties of cyanidin-based anthocyanin pigments. | 2002 | J. Agric. Food Chem. | pmid:12358498 |
| Terahara N et al. | Functional new acylated sophoroses and deglucosylated anthocyanins in a fermented red vinegar. | 2009 | J. Agric. Food Chem. | pmid:19702267 |
| Harb J et al. | Changes in polyphenols and expression levels of related genes in 'Duke' blueberries stored under high CO2 levels. | 2014 | J. Agric. Food Chem. | pmid:24999801 |
| Kovinich N et al. | Identification of two anthocyanidin reductase genes and three red-brown soybean accessions with reduced anthocyanidin reductase 1 mRNA, activity, and seed coat proanthocyanidin amounts. | 2012 | J. Agric. Food Chem. | pmid:22107112 |
| Xie Q et al. | Accumulation and molecular regulation of anthocyanin in purple tumorous stem mustard (Brassica juncea var. tumida Tsen et Lee). | 2014 | J. Agric. Food Chem. | pmid:25055052 |
| Suzuki T et al. | Structural identification of anthocyanins and analysis of concentrations during growth and flowering in buckwheat (Fagopyrum esculentum Moench) petals. | 2007 | J. Agric. Food Chem. | pmid:17941697 |
| Ozga JA et al. | Characterization of cyanidin- and quercetin-derived flavonoids and other phenolics in mature saskatoon fruits (Amelanchier alnifolia Nutt.). | 2007 | J. Agric. Food Chem. | pmid:17994693 |
| Lin LZ et al. | LC-PDA-ESI/MS(n) identification of new anthocyanins in purple Bordeaux radish ( Raphanus sativus L. variety). | 2011 | J. Agric. Food Chem. | pmid:21513350 |
| Reichel M et al. | Changes in flavonoids and nonphenolic pigments during on-tree maturation and postharvest pericarp browning of litchi (Litchi chinensis Sonn.) as shown by HPLC-MSn. | 2011 | J. Agric. Food Chem. | pmid:21413696 |
| Cuevas-RodrÃguez EO et al. | Characterization of anthocyanins and proanthocyanidins in wild and domesticated Mexican blackberries (Rubus spp.). | 2010 | J. Agric. Food Chem. | pmid:20507066 |
| Li Z et al. | Effects of exogenous abscisic acid on yield, antioxidant capacities, and phytochemical contents of greenhouse grown lettuces. | 2010 | J. Agric. Food Chem. | pmid:20420437 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Mulabagal V et al. | Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. | 2009 | J. Agric. Food Chem. | pmid:19199585 |
| Pricelius S et al. | Substrate specificities of glycosidases from Aspergillus species pectinase preparations on elderberry anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19191672 |
| Vasco C et al. | Chemical composition and phenolic compound profile of mortiño (Vaccinium floribundum Kunth). | 2009 | J. Agric. Food Chem. | pmid:19719139 |
| Kohyama N et al. | Changes in anthocyanins in the grains of purple waxy hull-less barley during seed maturation and after harvest. | 2008 | J. Agric. Food Chem. | pmid:18558760 |
| Comeskey DJ et al. | Isolation and structural identification of the anthocyanin components of red kiwifruit. | 2009 | J. Agric. Food Chem. | pmid:19203266 |
| Kim SJ et al. | Identification of anthocyanins in the sprouts of buckwheat. | 2007 | J. Agric. Food Chem. | pmid:17580874 |
| Nicoué EE et al. | Anthocyanins in wild blueberries of Quebec: extraction and identification. | 2007 | J. Agric. Food Chem. | pmid:17579428 |
| Wang CY et al. | Increasing antioxidant activity and reducing decay of blueberries by essential oils. | 2008 | J. Agric. Food Chem. | pmid:18442248 |
| Walton MC et al. | The flavonol quercetin-3-glucoside inhibits cyanidin-3-glucoside absorption in vitro. | 2006 | J. Agric. Food Chem. | pmid:16787048 |
| Jordheim M et al. | Anthocyanins in berries of ribes including gooseberry cultivars with a high content of acylated pigments. | 2007 | J. Agric. Food Chem. | pmid:17579440 |
| Kim MJ et al. | Relationship between phenolic compounds, anthocyanins content and antioxidant activity in colored barley germplasm. | 2007 | J. Agric. Food Chem. | pmid:17516656 |
| Noda Y et al. | Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. | 2002 | J. Agric. Food Chem. | pmid:11754562 |
| Li L et al. | Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | 2009 | J. Agric. Food Chem. | pmid:19166352 |
| Longo L and Vasapollo G | Anthocyanins from bay (Laurus nobilis L.) berries. | 2005 | J. Agric. Food Chem. | pmid:16190671 |
| Mylnikov SV et al. | Rubus fruit juices affect lipid peroxidation in a Drosophila melanogaster model in vivo. | 2005 | J. Agric. Food Chem. | pmid:16190624 |
| Chirinos R et al. | High-performance liquid chromatography with photodiode array detection (HPLC-DAD)/HPLC-mass spectrometry (MS) profiling of anthocyanins from Andean Mashua Tubers (Tropaeolum tuberosum RuÃz and Pavón) and their contribution to the overall antioxidant activity. | 2006 | J. Agric. Food Chem. | pmid:16968067 |
| Felgines C et al. | Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans. | 2005 | J. Agric. Food Chem. | pmid:16190623 |
| Ichiyanagi T et al. | Bioavailability and tissue distribution of anthocyanins in bilberry (Vaccinium myrtillus L.) extract in rats. | 2006 | J. Agric. Food Chem. | pmid:16939312 |
| Pinelo M et al. | Effect of clarification techniques and rat intestinal extract incubation on phenolic composition and antioxidant activity of black currant juice. | 2006 | J. Agric. Food Chem. | pmid:16939310 |
| Al-Farsi M et al. | Comparison of antioxidant activity, anthocyanins, carotenoids, and phenolics of three native fresh and sun-dried date (Phoenix dactylifera L.) varieties grown in Oman. | 2005 | J. Agric. Food Chem. | pmid:16159191 |
| Ichiyanagi T et al. | Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. | 2006 | J. Agric. Food Chem. | pmid:16848510 |
| Abdel-Aal el-SM et al. | Anthocyanin composition in black, blue, pink, purple, and red cereal grains. | 2006 | J. Agric. Food Chem. | pmid:16787017 |
| McDougall GJ et al. | Anthocyanin-flavanol condensation products from black currant (Ribes nigrum L.). | 2005 | J. Agric. Food Chem. | pmid:16190645 |
| Jayaprakasam B et al. | Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. | 2005 | J. Agric. Food Chem. | pmid:15631504 |
| Ichiyanagi T et al. | Metabolic pathway of cyanidin 3-O-beta-D-glucopyranoside in rats. | 2005 | J. Agric. Food Chem. | pmid:15631521 |
| Hillebrand S et al. | Characterization of anthocyanins and pyranoanthocyanins from blood orange [Citrus sinensis (L.) Osbeck] juice. | 2004 | J. Agric. Food Chem. | pmid:15563216 |
| Lee JH and Talcott ST | Fruit maturity and juice extraction influences ellagic acid derivatives and other antioxidant polyphenolics in muscadine grapes. | 2004 | J. Agric. Food Chem. | pmid:14733522 |
| Gonçalves B et al. | Effect of ripeness and postharvest storage on the phenolic profiles of Cherries (Prunus avium L.). | 2004 | J. Agric. Food Chem. | pmid:14759143 |
| Beckwith AG et al. | Relationship of light quantity and anthocyanin production in Pennisetum setaceum Cvs. rubrum and red riding hood. | 2004 | J. Agric. Food Chem. | pmid:14759132 |
| Wang H et al. | Characterization of anthocyanins in grape juices by ion trap liquid chromatography-mass spectrometry. | 2003 | J. Agric. Food Chem. | pmid:12643639 |
| Caldwell CR | Alkylperoxyl radical scavenging activity of red leaf lettuce (Lactuca sativa L.) phenolics. | 2003 | J. Agric. Food Chem. | pmid:14705882 |
| Wang J and Mazza G | Inhibitory effects of anthocyanins and other phenolic compounds on nitric oxide production in LPS/IFN-gamma-activated RAW 264.7 macrophages. | 2002 | J. Agric. Food Chem. | pmid:11829656 |
| Nyman NA and Kumpulainen JT | Determination of anthocyanidins in berries and red wine by high-performance liquid chromatography. | 2001 | J. Agric. Food Chem. | pmid:11559107 |
| Matsumoto H et al. | Stimulatory effect of cyanidin 3-glycosides on the regeneration of rhodopsin. | 2003 | J. Agric. Food Chem. | pmid:12769524 |
| Abdel-Aal el-SM and Hucl P | Composition and stability of anthocyanins in blue-grained wheat. | 2003 | J. Agric. Food Chem. | pmid:12670152 |
| Lai YS et al. | The Dark-Purple Tea Cultivar 'Ziyan' Accumulates a Large Amount of Delphinidin-Related Anthocyanins. | 2016 | J. Agric. Food Chem. | pmid:26996195 |
| Stintzing FC et al. | A novel zwitterionic anthocyanin from evergreen blackberry (Rubus laciniatus Willd.). | 2002 | J. Agric. Food Chem. | pmid:11782214 |