Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lin LZ and Harnly JM | Phenolic compounds and chromatographic profiles of pear skins (Pyrus spp.). | 2008 | J. Agric. Food Chem. | pmid:18778075 |
| Xu F et al. | Molecular cloning and function analysis of an anthocyanidin synthase gene from Ginkgo biloba, and its expression in abiotic stress responses. | 2008 | Mol. Cells | pmid:18779661 |
| Nicoletti I et al. | Identification and quantification of phenolic compounds in grapes by HPLC-PDA-ESI-MS on a semimicro separation scale. | 2008 | J. Agric. Food Chem. | pmid:18781764 |
| Meng S et al. | Natural dyes adsorbed on TiO2 nanowire for photovoltaic applications: enhanced light absorption and ultrafast electron injection. | 2008 | Nano Lett. | pmid:18788788 |
| Garcia-Alonso M et al. | Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. | 2009 | J. Nutr. Biochem. | pmid:18789665 |
| Merzlyak MN et al. | Light absorption by anthocyanins in juvenile, stressed, and senescing leaves. | 2008 | J. Exp. Bot. | pmid:18796701 |
| Tarozzi A et al. | Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity. | 2008 | Neuroreport | pmid:18797302 |
| Osmani SA et al. | Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. | 2008 | Plant Physiol. | pmid:18829982 |
| Conn S et al. | Purification, molecular cloning, and characterization of glutathione S-transferases (GSTs) from pigmented Vitis vinifera L. cell suspension cultures as putative anthocyanin transport proteins. | 2008 | J. Exp. Bot. | pmid:18836188 |
| Matsunaga N et al. | Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In Vivo. | 2010 | Evid Based Complement Alternat Med | pmid:18955266 |
| De Rosso VV et al. | Singlet oxygen quenching by anthocyanin's flavylium cations. | 2008 | Free Radic. Res. | pmid:18985487 |
| Li CY et al. | Corn husk as a potential source of anthocyanins. | 2008 | J. Agric. Food Chem. | pmid:19007127 |
| Han FL et al. | Principal component regression analysis of the relation between CIELAB color and monomeric anthocyanins in young Cabernet Sauvignon wines. | 2008 | Molecules | pmid:19015625 |
| Noda Y et al. | Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine. | 2008 | J Clin Biochem Nutr | pmid:19015753 |
| Li CY et al. | Gastroprotective effect of cyanidin 3-glucoside on ethanol-induced gastric lesions in rats. | 2008 | Alcohol | pmid:19038699 |
| Hassimotto NM et al. | Antioxidant status in humans after consumption of blackberry (Rubus fruticosus L.) juices with and without defatted milk. | 2008 | J. Agric. Food Chem. | pmid:19053224 |
| Knaup B et al. | Anthocyanins as lipoxygenase inhibitors. | 2009 | Mol Nutr Food Res | pmid:19072887 |
| Hassimotto NM et al. | Absorption and metabolism of cyanidin-3-glucoside and cyanidin-3-rutinoside extracted from wild mulberry (Morus nigra L.) in rats. | 2008 | Nutr Res | pmid:19083408 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Meng L et al. | Antioxidant activities of polyphenols extracted from Perilla frutescens varieties. | 2008 | Molecules | pmid:19127243 |
| Matus JT et al. | Post-veraison sunlight exposure induces MYB-mediated transcriptional regulation of anthocyanin and flavonol synthesis in berry skins of Vitis vinifera. | 2009 | J. Exp. Bot. | pmid:19129169 |
| Ugalde CM et al. | Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers. | 2009 | Pharm. Res. | pmid:19137418 |
| Vasco C et al. | Phenolic compounds in Rosaceae fruits from Ecuador. | 2009 | J. Agric. Food Chem. | pmid:19143537 |
| Kassim A et al. | Environmental and seasonal influences on red raspberry anthocyanin antioxidant contents and identification of quantitative traits loci (QTL). | 2009 | Mol Nutr Food Res | pmid:19156716 |
| Bellido GG and Beta T | Anthocyanin composition and oxygen radical scavenging capacity (ORAC) of milled and pearled purple, black, and common barley. | 2009 | J. Agric. Food Chem. | pmid:19159302 |
| Li L et al. | Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. | 2009 | J. Agric. Food Chem. | pmid:19166352 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Bjorøy O et al. | C-glycosylanthocyanidins synthesized from C-glycosylflavones. | 2009 | Phytochemistry | pmid:19185884 |
| Pricelius S et al. | Substrate specificities of glycosidases from Aspergillus species pectinase preparations on elderberry anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19191672 |
| Yanamala N et al. | pH-dependent interaction of rhodopsin with cyanidin-3-glucoside. 1. Structural aspects. | Photochem. Photobiol. | pmid:19192199 | |
| Mulabagal V et al. | Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. | 2009 | J. Agric. Food Chem. | pmid:19199585 |
| Walton MC et al. | Viscous food matrix influences absorption and excretion but not metabolism of blackcurrant anthocyanins in rats. | J. Food Sci. | pmid:19200098 | |
| Comeskey DJ et al. | Isolation and structural identification of the anthocyanin components of red kiwifruit. | 2009 | J. Agric. Food Chem. | pmid:19203266 |
| Tirupula KC et al. | pH-dependent interaction of rhodopsin with cyanidin-3-glucoside. 2. Functional aspects. | Photochem. Photobiol. | pmid:19267871 | |
| Dai J et al. | A comprehensive study of anthocyanin-containing extracts from selected blackberry cultivars: extraction methods, stability, anticancer properties and mechanisms. | 2009 | Food Chem. Toxicol. | pmid:19271318 |
| Osmani SA et al. | Effect of glucuronosylation on anthocyanin color stability. | 2009 | J. Agric. Food Chem. | pmid:19281238 |
| Thomasset S et al. | Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? | 2009 | Cancer Chemother. Pharmacol. | pmid:19294386 |
| Gomez C et al. | Grapevine MATE-type proteins act as vacuolar H+-dependent acylated anthocyanin transporters. | 2009 | Plant Physiol. | pmid:19297587 |
| He J et al. | Stability of black raspberry anthocyanins in the digestive tract lumen and transport efficiency into gastric and small intestinal tissues in the rat. | 2009 | J. Agric. Food Chem. | pmid:19317488 |
| Kim SH et al. | Structural identification and antioxidant properties of major anthocyanin extracted from Omija (Schizandra chinensis) fruit. | 2009 | J. Food Sci. | pmid:19323727 |
| Lehtonen HM et al. | Urinary excretion of the main anthocyanin in lingonberry (Vaccinium vitis-idaea), cyanidin 3-O-galactoside, and its metabolites. | 2009 | J. Agric. Food Chem. | pmid:19351112 |
| Marczylo TH et al. | Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice. | 2009 | Cancer Chemother. Pharmacol. | pmid:19363608 |
| Peel GJ et al. | The LAP1 MYB transcription factor orchestrates anthocyanidin biosynthesis and glycosylation in Medicago. | 2009 | Plant J. | pmid:19368693 |
| Nunn AV et al. | Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? | 2009 | Nutr Metab (Lond) | pmid:19371409 |
| Singh K et al. | Differential display mediated cloning of anthocyanidin reductase gene from tea (Camellia sinensis) and its relationship with the concentration of epicatechins. | 2009 | Tree Physiol. | pmid:19380395 |
| Albert NW et al. | Light-induced vegetative anthocyanin pigmentation in Petunia. | 2009 | J. Exp. Bot. | pmid:19380423 |
| Chen G et al. | Cyanidin-3-glucoside reverses ethanol-induced inhibition of neurite outgrowth: role of glycogen synthase kinase 3 Beta. | 2009 | Neurotox Res | pmid:19384566 |
| Garzón GA et al. | Determination of anthocyanins, total phenolic content, and antioxidant activity in Andes Berry (Rubus glaucus Benth). | 2009 | J. Food Sci. | pmid:19397707 |
| Philpott M et al. | Dietary protection against free radicals: a case for multiple testing to establish structure-activity relationships for antioxidant potential of anthocyanic plant species. | 2009 | Int J Mol Sci | pmid:19399239 |