Cyanidin is a lipid of Polyketides (PK) class. Cyanidin is associated with abnormalities such as Consumption-archaic term for TB, furuncle, Obesity, Cardiovascular Diseases and Endothelial dysfunction. The involved functions are known as anthocyanin biosynthetic process, Regulation, flavonoid biosynthetic process, Anabolism and anthocyanin metabolic process. Cyanidin often locates in Body tissue, integral to membrane, Autonomic nervous system, Blood and Tissue membrane. The associated genes with Cyanidin are anthocyanidin synthase, SLC2A8 gene, EPB41L2 gene, NKS1 gene and GLUCOSIDASE. The related lipids are Butanols. The related experimental models are Knock-out.
To understand associated biological information of Cyanidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cyanidin is suspected in Obesity, Chronic Disease, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Heart Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cyanidin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xu M et al. | Cyanidin-3-glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2. | 2010 | Mol. Cancer | pmid:21034468 |
| Ozgen M et al. | Total phenolic, anthocyanin contents and antioxidant capacity of selected elderberry (Sambucus canadensis L.) accessions. | 2010 | Pharmacogn Mag | pmid:20931079 |
| Pourcel L et al. | The formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and implications for the sequestration of anthocyanin pigments. | 2010 | Mol Plant | pmid:20085894 |
| Sahay A and Shakya M | Structure prediction of dihydroflavonol 4- reductase and anthocyanidin synthase from spinach. | 2010 | Bioinformation | pmid:21364828 |
| Ozen T and Türkekul I | Antioxidant activities of Sarcodon imbricatum wildly grown in the Black Sea Region of Turkey. | 2010 | Pharmacogn Mag | pmid:20668572 |
| Titta L et al. | Blood orange juice inhibits fat accumulation in mice. | 2010 | Int J Obes (Lond) | pmid:20029381 |
| Morant M et al. | Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2. | 2010 | Mol Plant | pmid:20008451 |
| Ojeda D et al. | Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa. | 2010 | J Ethnopharmacol | pmid:19808084 |
| Shi MZ and Xie DY | Features of anthocyanin biosynthesis in pap1-D and wild-type Arabidopsis thaliana plants grown in different light intensity and culture media conditions. | 2010 | Planta | pmid:20309578 |
| Choi MJ et al. | Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system. | 2010 | Biol. Pharm. Bull. | pmid:20190403 |
| Kim JE et al. | Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. | 2010 | Biochem. Pharmacol. | pmid:20096264 |
| Andersen ØM et al. | Anthocyanins with unusual furanose sugar (apiose) from leaves of Synadenium grantii (Euphorbiaceae). | 2010 | Phytochemistry | pmid:20594565 |
| Zhu F et al. | Anthocyanins, hydroxycinnamic acid derivatives, and antioxidant activity in roots of different chinese purple-fleshed sweetpotato genotypes. | 2010 | J. Agric. Food Chem. | pmid:20524661 |
| Cuevas-RodrÃguez EO et al. | Characterization of anthocyanins and proanthocyanidins in wild and domesticated Mexican blackberries (Rubus spp.). | 2010 | J. Agric. Food Chem. | pmid:20507066 |
| Liu J et al. | Bog bilberry (Vaccinium uliginosum L.) extract reduces cultured Hep-G2, Caco-2, and 3T3-L1 cell viability, affects cell cycle progression, and has variable effects on membrane permeability. | 2010 | J. Food Sci. | pmid:20492295 |
| Li Z et al. | Effects of exogenous abscisic acid on yield, antioxidant capacities, and phytochemical contents of greenhouse grown lettuces. | 2010 | J. Agric. Food Chem. | pmid:20420437 |
| Zhang Y et al. | Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. | 2010 | Inflamm. Res. | pmid:20309718 |
| Delazar A et al. | Isolation and free-radical-scavenging properties of cyanidin 3-O-glycosides from the fruits of Ribes biebersteinii Berl. | 2010 | Acta Pharm | pmid:20228037 |
| Prior RL et al. | Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet. | 2010 | J. Agric. Food Chem. | pmid:20201554 |
| Wyzgoski FJ et al. | Modeling relationships among active components in black raspberry (Rubus occidentalis L.) fruit extracts using high-resolution (1)H nuclear magnetic resonance (NMR) spectroscopy and multivariate statistical analysis. | 2010 | J. Agric. Food Chem. | pmid:20192269 |
| Felgines C et al. | Radiolabelled cyanidin 3-O-glucoside is poorly absorbed in the mouse. | 2010 | Br. J. Nutr. | pmid:20187984 |
| Choi JY et al. | Analysis and tentative structure elucidation of new anthocyanins in fruit peel of Vitis coignetiae Pulliat (meoru) using LC-MS/MS: Contribution to the overall antioxidant activity. | 2010 | J Sep Sci | pmid:20187032 |
| Sreerama YN et al. | Variability in the distribution of phenolic compounds in milled fractions of chickpea and horse gram: evaluation of their antioxidant properties. | 2010 | J. Agric. Food Chem. | pmid:20593828 |
| Akkarachiyasit S et al. | Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase. | 2010 | Int J Mol Sci | pmid:20957102 |
| Yang Y et al. | Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21135223 |
| Lopes-Lutz D et al. | Characterization and quantification of polyphenols in Amazon grape (Pourouma cecropiifolia Martius). | 2010 | Molecules | pmid:21116224 |
| Okazaki Y et al. | A beverage containing fermented black soybean ameliorates ferric nitrilotriacetate-induced renal oxidative damage in rats. | 2010 | J Clin Biochem Nutr | pmid:21103028 |
| Falginella L et al. | Expansion and subfunctionalisation of flavonoid 3',5'-hydroxylases in the grapevine lineage. | 2010 | BMC Genomics | pmid:20939908 |
| Sasaki K et al. | Functional divergence within class B MADS-box genes TfGLO and TfDEF in Torenia fournieri Lind. | 2010 | Mol. Genet. Genomics | pmid:20872230 |
| Chiu LW et al. | The purple cauliflower arises from activation of a MYB transcription factor. | 2010 | Plant Physiol. | pmid:20855520 |
| Ono E et al. | Functional differentiation of the glycosyltransferases that contribute to the chemical diversity of bioactive flavonol glycosides in grapevines (Vitis vinifera). | 2010 | Plant Cell | pmid:20693356 |
| Kovinich N et al. | Functional characterization of a UDP-glucose:flavonoid 3-O-glucosyltransferase from the seed coat of black soybean (Glycine max (L.) Merr.). | 2010 | Phytochemistry | pmid:20621794 |
| Cvorovic J et al. | Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells. | 2010 | Arch. Biochem. Biophys. | pmid:20494645 |
| Stushnoff C et al. | Flavonoid profiling and transcriptome analysis reveals new gene-metabolite correlations in tubers of Solanum tuberosum L. | 2010 | J. Exp. Bot. | pmid:20110266 |
| Matsunaga N et al. | Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In Vivo. | 2010 | Evid Based Complement Alternat Med | pmid:18955266 |
| Fortalezas S et al. | Antioxidant properties and neuroprotective capacity of strawberry tree fruit (Arbutus unedo). | 2010 | Nutrients | pmid:22254017 |
| Bedon F et al. | Subgroup 4 R2R3-MYBs in conifer trees: gene family expansion and contribution to the isoprenoid- and flavonoid-oriented responses. | 2010 | J. Exp. Bot. | pmid:20732878 |
| Gutha LR et al. | Modulation of flavonoid biosynthetic pathway genes and anthocyanins due to virus infection in grapevine (Vitis vinifera L.) leaves. | 2010 | BMC Plant Biol. | pmid:20731850 |
| Pandey KB and Rizvi SI | Plant polyphenols as dietary antioxidants in human health and disease. | 2009 Nov-Dec | Oxid Med Cell Longev | pmid:20716914 |
| Burdulis D et al. | Comparative study of anthocyanin composition, antimicrobial and antioxidant activity in bilberry (Vaccinium myrtillus L.) and blueberry (Vaccinium corymbosum L.) fruits. | 2009 Jul-Aug | Acta Pol Pharm | pmid:19702172 |
| Sutela S et al. | Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch. | 2009 | BMC Plant Biol. | pmid:19788757 |
| Auger B et al. | Brassica orthologs from BANYULS belong to a small multigene family, which is involved in procyanidin accumulation in the seed. | 2009 | Planta | pmid:19760260 |
| Moraga AR et al. | Cloning and characterization of a glucosyltransferase from Crocus sativus stigmas involved in flavonoid glucosylation. | 2009 | BMC Plant Biol. | pmid:19695093 |
| Butryee C et al. | Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf. | 2009 | Int J Food Sci Nutr | pmid:19572229 |
| Li JB et al. | A new acylated anthocyanin from the red flowers of Camellia hongkongensis and characterization of anthocyanins in the section Camellia species. | 2009 | J Integr Plant Biol | pmid:19522813 |
| Nakabayashi R et al. | Metabolomics-oriented isolation and structure elucidation of 37 compounds including two anthocyanins from Arabidopsis thaliana. | 2009 | Phytochemistry | pmid:19497599 |
| Jin J et al. | Analysis of phytochemical composition and chemoprotective capacity of rocket (Eruca sativa and Diplotaxis tenuifolia) leafy salad following cultivation in different environments. | 2009 | J. Agric. Food Chem. | pmid:19489541 |
| Cao S et al. | A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. | 2009 | J. Agric. Food Chem. | pmid:19099393 |
| Fernandes I et al. | Enzymatic hemisynthesis of metabolites and conjugates of anthocyanins. | 2009 | J. Agric. Food Chem. | pmid:19113877 |
| Knaup B et al. | Anthocyanins as lipoxygenase inhibitors. | 2009 | Mol Nutr Food Res | pmid:19072887 |