| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cystitis | D003556 | 23 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
Total
2
Pelargonidin
Pelargonidin is a lipid of Polyketides (PK) class. The involved functions are known as Uptake, Intestinal Absorption, glucose uptake, Process and Metabolic Inhibition. Pelargonidin often locates in Serosal, Mucous Membrane, brush border membrane, Membrane and Cell surface. The associated genes with Pelargonidin are SLC5A1 gene, SLC2A2 gene, Homologous Gene, F3 gene and CRSP3 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Pelargonidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pelargonidin?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pelargonidin
PubChem Associated disorders and diseases
What pathways are associated with Pelargonidin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pelargonidin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Pelargonidin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pelargonidin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Pelargonidin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Pelargonidin?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Pelargonidin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Sohanaki H et al. | Pelargonidin Improves Passive Avoidance Task Performance in a Rat Amyloid Beta25-35 Model of Alzheimer's Disease Via Estrogen Receptor Independent Pathways. | 2016 | Acta Med Iran | pmid:27309265 |
| Kang H et al. | Suppressive Effects of Pelargonidin on Endothelial Protein C Receptor Shedding via the Inhibition of TACE Activity and MAP Kinases. | 2016 | Am. J. Chin. Med. | pmid:27222063 |
| Forni C et al. | Role of transglutaminase 2 in quercetin-induced differentiation of B16-F10 murine melanoma cells. | 2009 | Amino Acids | pmid:18688565 |
| De Rosso M et al. | Study of anthocyanic profiles of twenty-one hybrid grape varieties by liquid chromatography and precursor-ion mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22688043 |
| Sugita O et al. | A new method of measuring the antioxidant activity of polyphenols using cumene hydroperoxide. | 2004 | Ann. Clin. Biochem. | pmid:14713390 |
| Ross JA and Kasum CM | Dietary flavonoids: bioavailability, metabolic effects, and safety. | 2002 | Annu. Rev. Nutr. | pmid:12055336 |
| Vauzour D et al. | Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols. | 2008 | Arch. Biochem. Biophys. | pmid:18394421 |
| Cvorovic J et al. | Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells. | 2010 | Arch. Biochem. Biophys. | pmid:20494645 |
| Vafeiadou K et al. | The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. | 2009 | Arch. Biochem. Biophys. | pmid:19467635 |
| Xie DY et al. | Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana. | 2004 | Arch. Biochem. Biophys. | pmid:14725861 |
| Lee IC and Bae JS | Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses. | 2017 | Arch. Pharm. Res. | pmid:27826751 |
| Min G et al. | Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. | 2016 | Arch. Pharm. Res. | pmid:27778275 |
| Ku SK et al. | Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. | 2016 | Arch. Pharm. Res. | pmid:26762345 |
| Abe Y et al. | Detection of 1-O-malylglucose: pelargonidin 3-O-glucose-6''-O-malyltransferase activity in carnation (Dianthus caryophyllus). | 2008 | Biochem. Biophys. Res. Commun. | pmid:18471436 |
| Dreiseitel A et al. | Inhibition of proteasome activity by anthocyanins and anthocyanidins. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18460339 |
| Son JE et al. | Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. | 2014 | Biochem. Pharmacol. | pmid:24582770 |
| Hou DX et al. | Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. | 2005 | Biochem. Pharmacol. | pmid:15963474 |
| Grigoriev SM et al. | Regulation of mitochondrial KATP channel by redox agents. | 1999 | Biochim. Biophys. Acta | pmid:10076019 |
| Sahay A and Shakya M | Structure prediction of dihydroflavonol 4- reductase and anthocyanidin synthase from spinach. | 2010 | Bioinformation | pmid:21364828 |
| Ganugapati J et al. | Molecular docking studies of banana flower flavonoids as insulin receptor tyrosine kinase activators as a cure for diabetes mellitus. | 2012 | Bioinformation | pmid:22493522 |
| Marinov BS and Ruzieva RKh | [Opposite control of O2 affinity for hemoglobin by donors and acceptors]. | 1990 | Biokhimiia | pmid:2078638 |
| Gargouri M et al. | The epimerase activity of anthocyanidin reductase from Vitis vinifera and its regiospecific hydride transfers. | Biol. Chem. | pmid:20030585 | |
| Sohanaki H et al. | Pelargonidin improves memory deficit in amyloid β25-35 rat model of Alzheimer's disease by inhibition of glial activation, cholinesterase, and oxidative stress. | 2016 | Biomed. Pharmacother. | pmid:27470554 |
| Takasawa R et al. | Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. | 2010 | Bioorg. Med. Chem. | pmid:20801663 |
| Ku CS and Mun SP | Optimization of the extraction of anthocyanin from Bokbunja (Rubus coreanus Miq.) marc produced during traditional wine processing and characterization of the extracts. | 2008 | Bioresour. Technol. | pmid:18456493 |
| Kaneko T et al. | Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human fibroblasts by anthocyanidins. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12843669 |
| Tanaka Y et al. | Flower color modification by engineering of the flavonoid biosynthetic pathway: practical perspectives. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20834175 |
| Yan Y et al. | High-yield anthocyanin biosynthesis in engineered Escherichia coli. | 2008 | Biotechnol. Bioeng. | pmid:18023053 |
| Su V and Hsu BD | Cloning and expression of a putative cytochrome P450 gene that influences the colour of Phalaenopsis flowers. | 2003 | Biotechnol. Lett. | pmid:14719829 |
| Aksamit-Stachurska A et al. | Glycosyltransferase efficiently controls phenylpropanoid pathway. | 2008 | BMC Biotechnol. | pmid:18321380 |
| Kovinich N et al. | Combined analysis of transcriptome and metabolite data reveals extensive differences between black and brown nearly-isogenic soybean (Glycine max) seed coats enabling the identification of pigment isogenes. | 2011 | BMC Genomics | pmid:21801362 |
| Grimplet J et al. | Tissue-specific mRNA expression profiling in grape berry tissues. | 2007 | BMC Genomics | pmid:17584945 |
| Irani NG and Grotewold E | Light-induced morphological alteration in anthocyanin-accumulating vacuoles of maize cells. | 2005 | BMC Plant Biol. | pmid:15907203 |
| Payyavula RS et al. | Differential effects of environment on potato phenylpropanoid and carotenoid expression. | 2012 | BMC Plant Biol. | pmid:22429339 |
| Gillman JD et al. | Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in brown hilum and brown seed coats. | 2011 | BMC Plant Biol. | pmid:22070454 |
| Boase MR et al. | Isolation and antisense suppression of flavonoid 3', 5'-hydroxylase modifies flower pigments and colour in cyclamen. | 2010 | BMC Plant Biol. | pmid:20540805 |
| Chagné D et al. | QTL and candidate gene mapping for polyphenolic composition in apple fruit. | 2012 | BMC Plant Biol. | pmid:22269060 |
| Telias A et al. | Apple skin patterning is associated with differential expression of MYB10. | 2011 | BMC Plant Biol. | pmid:21599973 |
| Zamora-Ros R et al. | Estimation of the intake of anthocyanidins and their food sources in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. | 2011 | Br. J. Nutr. | pmid:21481290 |
| Azzini E et al. | Bioavailability of strawberry antioxidants in human subjects. | 2010 | Br. J. Nutr. | pmid:20487578 |
| Felgines C et al. | Strawberry pelargonidin glycosides are excreted in urine as intact glycosides and glucuronidated pelargonidin derivatives in rats. | 2007 | Br. J. Nutr. | pmid:17559698 |
| Edirisinghe I et al. | Strawberry anthocyanin and its association with postprandial inflammation and insulin. | 2011 | Br. J. Nutr. | pmid:21736853 |
| El Mohsen MA et al. | Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. | 2006 | Br. J. Nutr. | pmid:16441916 |
| Dreiseitel A et al. | Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1. | 2009 | Br. J. Pharmacol. | pmid:19922539 |
| Roghani M et al. | Oral pelargonidin exerts dose-dependent neuroprotection in 6-hydroxydopamine rat model of hemi-parkinsonism. | 2010 | Brain Res. Bull. | pmid:20558255 |
| Jeong S et al. | Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses. | 2017 | Can. J. Physiol. Pharmacol. | pmid:28060523 |
| Bakowska-Barczak AM et al. | Survey of bioactive components in Western Canadian berries. | 2007 | Can. J. Physiol. Pharmacol. | pmid:18066116 |
| Lamy S et al. | Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. | 2006 | Carcinogenesis | pmid:16308314 |
| Xu Y et al. | Pelargonidin-3-O-rutinoside as a novel α-glucosidase inhibitor for improving postprandial hyperglycemia. | 2018 | Chem. Commun. (Camb.) | pmid:30394469 |
| Tamura S et al. | Six new acylated anthocyanins from red radish (Raphanus sativus). | 2010 | Chem. Pharm. Bull. | pmid:20823613 |
| Habermeyer M et al. | Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity. | 2005 | Chem. Res. Toxicol. | pmid:16167831 |
| Warskulat AC et al. | Unprecedented Utilization of Pelargonidin and Indole for the Biosynthesis of Plant Indole Alkaloids. | 2016 | Chembiochem | pmid:26670055 |
| Karthi N et al. | Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach. | 2017 | Comput Biol Chem | pmid:28950208 |
| Khandelwal N and Abraham SK | Intake of anthocyanidins pelargonidin and cyanidin reduces genotoxic stress in mice induced by diepoxybutane, urethane and endogenous nitrosation. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24642102 |
| Samadder A et al. | Nanopharmaceutical approach using pelargonidin towards enhancement of efficacy for prevention of alloxan-induced DNA damage in L6 cells via activation of PARP and p53. | 2016 | Environ. Toxicol. Pharmacol. | pmid:26943895 |
| Lee H et al. | Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22454682 |
| Choi JG et al. | In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. | 2011 | Evid Based Complement Alternat Med | pmid:19687188 |
| Naudi A et al. | Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress. | 2012 | Exp Diabetes Res | pmid:22253615 |
| Müller-Maatsch J et al. | Co-pigmentation of pelargonidin derivatives in strawberry and red radish model solutions by the addition of phenolic fractions from mango peels. | 2016 | Food Chem | pmid:27451227 |
| Arroyo-Maya IJ et al. | Characterization of flavonoid-protein interactions using fluorescence spectroscopy: Binding of pelargonidin to dairy proteins. | 2016 | Food Chem | pmid:27451201 |
| Chen W et al. | Protective effect of wild raspberry (Rubus hirsutus Thunb.) extract against acrylamide-induced oxidative damage is potentiated after simulated gastrointestinal digestion. | 2016 | Food Chem | pmid:26593576 |
| Espin S et al. | Phenolic composition and antioxidant capacity of yellow and purple-red Ecuadorian cultivars of tree tomato (Solanum betaceum Cav.). | 2016 | Food Chem | pmid:26471655 |
| Kamonpatana K et al. | Susceptibility of anthocyanins to ex vivo degradation in human saliva. | 2012 | Food Chem | pmid:22868153 |
| González-Barrio R et al. | Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds. | 2018 | Food Chem | pmid:29478556 |
| Dimitrić Marković JM et al. | Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms. | 2017 | Food Chem | pmid:27719933 |
| Wang LS et al. | Antioxidant and pro-oxidant properties of acylated pelargonidin derivatives extracted from red radish (Raphanus sativus var. niger, Brassicaceae). | 2010 | Food Chem. Toxicol. | pmid:20600520 |
| Shih PH et al. | Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. | 2005 | Food Chem. Toxicol. | pmid:15964118 |
| Riha J et al. | Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes. | 2015 | Food Funct | pmid:25578040 |
| Oancea AM et al. | The kinetics of thermal degradation of polyphenolic compounds from elderberry ( Sambucus nigra L.) extract. | 2018 | Food Sci Technol Int | pmid:29409346 |
| Rahman MM et al. | Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. | 2006 | Free Radic. Res. | pmid:17015281 |
| Wink M et al. | Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents. | 2012 | Front Microbiol | pmid:22536197 |
| Wang L et al. | Purification and cloning of a Chinese red radish peroxidase that metabolise pelargonidin and forms a gene family in Brassicaceae. | 2004 | Gene | pmid:15588587 |
| Hidalgo M et al. | Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites. | 2012 | Genes Nutr | pmid:22218934 |
| Sharma M et al. | Identification of the pr1 gene product completes the anthocyanin biosynthesis pathway of maize. | 2011 | Genetics | pmid:21385724 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Gastrointestinal pharmacology. | 2008 | Indian J Pharmacol | pmid:21593966 | |
| Cherian S et al. | Antidiabetic effect of a glycoside of pelargonidin isolated from the bark of Ficus bengalensis Linn. | 1992 | Indian J. Biochem. Biophys. | pmid:1427968 |
| Cherian S and Augusti KT | Antidiabetic effects of a glycoside of leucopelargonidin isolated from Ficus bengalensis Linn. | 1993 | Indian J. Exp. Biol. | pmid:8500813 |
| Reber JD et al. | Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries. | 2011 | Int J Food Sci Nutr | pmid:21385007 |
| Halbwirth H | The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. | 2010 | Int J Mol Sci | pmid:20386656 |
| Zhu L et al. | Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. | 2012 | Int J Mol Sci | pmid:22489164 |
| Zhao Q et al. | Anthocyanins profile of grape berries of Vitis amurensis, its hybrids and their wines. | 2010 | Int J Mol Sci | pmid:20559511 |
| de Pascual-Teresa S et al. | Flavanols and anthocyanins in cardiovascular health: a review of current evidence. | 2010 | Int J Mol Sci | pmid:20480037 |
| Treutter D | Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. | 2010 | Int J Mol Sci | pmid:20479987 |
| Tanaka Y et al. | Recent progress of flower colour modification by biotechnology. | 2009 | Int J Mol Sci | pmid:20054474 |
| Wang BL et al. | Treating acute cystitis with biodegradable micelle-encapsulated quercetin. | 2012 | Int J Nanomedicine | pmid:22661886 |
| Dhivya S et al. | Impact of Anthocyanidins on Mitoxantrone-Induced Cytotoxicity and Genotoxicity: An In Vitro and In Vivo Analysis. | 2016 | Integr Cancer Ther | pmid:27146128 |
| Mirshekar M et al. | Chronic oral pelargonidin alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: involvement of oxidative stress. | 2010 Jan-Apr | Iran. Biomed. J. | pmid:20683496 |
| Kurka O et al. | Semisynthesis and spectral characterization of 5-methylpyranopelargonidin and 4-methylfuropelargonidin and their separation and detection in strawberry fruit wine. | 2017 | J Chromatogr A | pmid:28648259 |
| Åata E et al. | Vulnerability of anthocyanins to the components of a thin-layer chromatographic system and comprehensive screening of anthocyanes in alimentary products. | 2018 | J Chromatogr A | pmid:30150119 |
| Tian Q et al. | Screening for anthocyanins using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry with precursor-ion analysis, product-ion analysis, common-neutral-loss analysis, and selected reaction monitoring. | 2005 | J Chromatogr A | pmid:16395794 |
| Åata E et al. | Novel thin-layer chromatographic method of screening the anthocyanes containing alimentary products and precautions taken at the method development step. | 2017 | J Chromatogr A | pmid:29173954 |
| Korte G et al. | An examination of anthocyanins' and anthocyanidins' affinity for cannabinoid receptors. | 2009 | J Med Food | pmid:20041802 |
| Aizza LC and Dornelas MC | A genomic approach to study anthocyanin synthesis and flower pigmentation in passionflowers. | 2011 | J Nucleic Acids | pmid:21772993 |
| Estévez L and Mosquera RA | Conformational and substitution effects on the electron distribution in a series of anthocyanidins. | 2009 | J Phys Chem A | pmid:19685919 |
| Estévez L and Mosquera RA | A density functional theory study on pelargonidin. | 2007 | J Phys Chem A | pmid:17929785 |
| Comandini P et al. | CZE separation of strawberry anthocyanins with acidic buffer and comparison with HPLC. | 2008 | J Sep Sci | pmid:18704996 |
| Yıldırım S et al. | Fast determination of anthocyanins and free pelargonidin in fruits, fruit juices, and fruit wines by high-performance liquid chromatography using a core-shell column. | 2016 | J Sep Sci | pmid:27550473 |
| Nicoué EE et al. | Anthocyanins in wild blueberries of Quebec: extraction and identification. | 2007 | J. Agric. Food Chem. | pmid:17579428 |