MeSH term | MeSH ID | Detail |
---|---|---|
Cystitis | D003556 | 23 associated lipids |
Parkinsonian Disorders | D020734 | 20 associated lipids |
Pelargonidin is a lipid of Polyketides (PK) class. The involved functions are known as Uptake, Intestinal Absorption, glucose uptake, Process and Metabolic Inhibition. Pelargonidin often locates in Serosal, Mucous Membrane, brush border membrane, Membrane and Cell surface. The associated genes with Pelargonidin are SLC5A1 gene, SLC2A2 gene, Homologous Gene, F3 gene and CRSP3 gene. The related experimental models are Knock-out.
To understand associated biological information of Pelargonidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Pelargonidin
MeSH term | MeSH ID | Detail |
---|---|---|
Cystitis | D003556 | 23 associated lipids |
Parkinsonian Disorders | D020734 | 20 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Åata E et al. | Vulnerability of anthocyanins to the components of a thin-layer chromatographic system and comprehensive screening of anthocyanes in alimentary products. | 2018 | J Chromatogr A | pmid:30150119 |
González-Barrio R et al. | Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds. | 2018 | Food Chem | pmid:29478556 |
Xu Y et al. | Pelargonidin-3-O-rutinoside as a novel α-glucosidase inhibitor for improving postprandial hyperglycemia. | 2018 | Chem. Commun. (Camb.) | pmid:30394469 |
Zhang Y et al. | Effect of Red and Blue Light on Anthocyanin Accumulation and Differential Gene Expression in Strawberry (Fragaria × ananassa). | 2018 | Molecules | pmid:29614032 |
Oancea AM et al. | The kinetics of thermal degradation of polyphenolic compounds from elderberry ( Sambucus nigra L.) extract. | 2018 | Food Sci Technol Int | pmid:29409346 |
Xie S et al. | Reduction of Dihydrokaempferol by Vitis vinfera Dihydroflavonol 4-Reductase to Produce Orange Pelargonidin-Type Anthocyanins. | 2018 | J. Agric. Food Chem. | pmid:29554804 |
Xu W et al. | Characterization of anthocyanins in the hybrid progenies derived from Iris dichotoma and I. domestica by HPLC-DAD-ESI/MS analysis. | 2018 | Phytochemistry | pmid:29550699 |
Yari A and Rashnoo S | Optimization of a new method for extraction of cyanidin chloride and pelargonidin chloride anthocyanins with magnetic solid phase extraction and determination in fruit samples by HPLC with central composite design. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28987497 |
Bashandy H and Teeri TH | Genetically engineered orange petunias on the market. | 2017 | Planta | pmid:28647812 |
Kurka O et al. | Semisynthesis and spectral characterization of 5-methylpyranopelargonidin and 4-methylfuropelargonidin and their separation and detection in strawberry fruit wine. | 2017 | J Chromatogr A | pmid:28648259 |
Samadder A et al. | Nano-Pelargonidin Protects Hyperglycemic-Induced L6 Cells against Mitochondrial Dysfunction. | 2017 | Planta Med. | pmid:28073120 |
Jeong S et al. | Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses. | 2017 | Can. J. Physiol. Pharmacol. | pmid:28060523 |
Lee IC and Bae JS | Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses. | 2017 | Arch. Pharm. Res. | pmid:27826751 |
Karthi N et al. | Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach. | 2017 | Comput Biol Chem | pmid:28950208 |
Åata E et al. | Novel thin-layer chromatographic method of screening the anthocyanes containing alimentary products and precautions taken at the method development step. | 2017 | J Chromatogr A | pmid:29173954 |
Servick K | The strange case of the orange petunias. | 2017 | Science | pmid:28546164 |
Dimitrić Marković JM et al. | Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms. | 2017 | Food Chem | pmid:27719933 |
Nankar AN et al. | Quantitative and qualitative evaluation of kernel anthocyanins from southwestern United States blue corn. | 2016 | J. Sci. Food Agric. | pmid:26879128 |
Min G et al. | Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. | 2016 | Arch. Pharm. Res. | pmid:27778275 |
Sohanaki H et al. | Pelargonidin improves memory deficit in amyloid β25-35 rat model of Alzheimer's disease by inhibition of glial activation, cholinesterase, and oxidative stress. | 2016 | Biomed. Pharmacother. | pmid:27470554 |
Müller-Maatsch J et al. | Co-pigmentation of pelargonidin derivatives in strawberry and red radish model solutions by the addition of phenolic fractions from mango peels. | 2016 | Food Chem | pmid:27451227 |
Arroyo-Maya IJ et al. | Characterization of flavonoid-protein interactions using fluorescence spectroscopy: Binding of pelargonidin to dairy proteins. | 2016 | Food Chem | pmid:27451201 |
Kang H et al. | Suppressive Effects of Pelargonidin on Endothelial Protein C Receptor Shedding via the Inhibition of TACE Activity and MAP Kinases. | 2016 | Am. J. Chin. Med. | pmid:27222063 |
Dhivya S et al. | Impact of Anthocyanidins on Mitoxantrone-Induced Cytotoxicity and Genotoxicity: An In Vitro and In Vivo Analysis. | 2016 | Integr Cancer Ther | pmid:27146128 |
Samadder A et al. | Nanopharmaceutical approach using pelargonidin towards enhancement of efficacy for prevention of alloxan-induced DNA damage in L6 cells via activation of PARP and p53. | 2016 | Environ. Toxicol. Pharmacol. | pmid:26943895 |
Park E et al. | A dose-response evaluation of freeze-dried strawberries independent of fiber content on metabolic indices in abdominally obese individuals with insulin resistance in a randomized, single-blinded, diet-controlled crossover trial. | 2016 | Mol Nutr Food Res | pmid:26842771 |
Ku SK et al. | Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. | 2016 | Arch. Pharm. Res. | pmid:26762345 |
Chen W et al. | Protective effect of wild raspberry (Rubus hirsutus Thunb.) extract against acrylamide-induced oxidative damage is potentiated after simulated gastrointestinal digestion. | 2016 | Food Chem | pmid:26593576 |
Espin S et al. | Phenolic composition and antioxidant capacity of yellow and purple-red Ecuadorian cultivars of tree tomato (Solanum betaceum Cav.). | 2016 | Food Chem | pmid:26471655 |
Sohanaki H et al. | Pelargonidin Improves Passive Avoidance Task Performance in a Rat Amyloid Beta25-35 Model of Alzheimer's Disease Via Estrogen Receptor Independent Pathways. | 2016 | Acta Med Iran | pmid:27309265 |
Park CH et al. | Metabolic Profiling and Antioxidant Assay of Metabolites from Three Radish Cultivars (Raphanus sativus). | 2016 | Molecules | pmid:26828471 |
Warskulat AC et al. | Unprecedented Utilization of Pelargonidin and Indole for the Biosynthesis of Plant Indole Alkaloids. | 2016 | Chembiochem | pmid:26670055 |
Yıldırım S et al. | Fast determination of anthocyanins and free pelargonidin in fruits, fruit juices, and fruit wines by high-performance liquid chromatography using a core-shell column. | 2016 | J Sep Sci | pmid:27550473 |
Lai YS et al. | The Dark-Purple Tea Cultivar 'Ziyan' Accumulates a Large Amount of Delphinidin-Related Anthocyanins. | 2016 | J. Agric. Food Chem. | pmid:26996195 |
Riha J et al. | Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes. | 2015 | Food Funct | pmid:25578040 |
Lim A et al. | Potential natural sensitizers extracted from the skin of Canarium odontophyllum fruits for dye-sensitized solar cells. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25541396 |
Junqueira-Gonçalves MP et al. | Isolation and characterization of phenolic compounds and anthocyanins from Murta (Ugni molinae Turcz.) fruits. Assessment of antioxidant and antibacterial activity. | 2015 | Molecules | pmid:25838172 |
Khandelwal N and Abraham SK | Protective effects of common anthocyanidins against genotoxic damage induced by chemotherapeutic drugs in mice. | 2014 | Planta Med. | pmid:25184891 |
Zhu Y et al. | Molecular cloning and functional characterization of the anthocyanidin reductase gene from Vitis bellula. | 2014 | Planta | pmid:24880552 |
Khandelwal N and Abraham SK | Intake of anthocyanidins pelargonidin and cyanidin reduces genotoxic stress in mice induced by diepoxybutane, urethane and endogenous nitrosation. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24642102 |
Somerset S and Papier K | A food frequency questionnaire validated for estimating dietary flavonoid intake in an Australian population. | 2014 | Nutr Cancer | pmid:25207829 |
Miosic S et al. | Dihydroflavonol 4-reductase genes encode enzymes with contrasting substrate specificity and show divergent gene expression profiles in Fragaria species. | 2014 | PLoS ONE | pmid:25393679 |
Lin YC et al. | Protective effect of anthocyanidins against sodium dithionite-induced hypoxia injury in C6 glial cells. | 2014 | J. Agric. Food Chem. | pmid:24845373 |
Son JE et al. | Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. | 2014 | Biochem. Pharmacol. | pmid:24582770 |
Lee MJ et al. | Characterization and quantitation of anthocyanins in purple-fleshed sweet potatoes cultivated in Korea by HPLC-DAD and HPLC-ESI-QTOF-MS/MS. | 2013 | J. Agric. Food Chem. | pmid:23464823 |
Ichiyanagi T et al. | Structural elucidation and biological fate of two glucuronyl metabolites of pelargonidin 3-O-β-D-glucopyranoside in rats. | 2013 | J. Agric. Food Chem. | pmid:23256460 |
Kamenickova A et al. | Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. | 2013 | Toxicol. Lett. | pmid:23735880 |
Kamenickova A et al. | Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. | 2013 | Toxicol. Lett. | pmid:23419638 |
Tatsuzawa F | 7-O-methylpelargonidin glycosides from the pale red flowers of Catharanthus roseus. | 2013 | Nat Prod Commun | pmid:24079176 |
Vodopivec BM et al. | Differences in the structure of anthocyanins from the two amphibious plants, Lobelia cardinalis and Nesaea crassicaulis. | 2013 | Nat. Prod. Res. | pmid:22694738 |
Naudi A et al. | Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress. | 2012 | Exp Diabetes Res | pmid:22253615 |
Wang BL et al. | Treating acute cystitis with biodegradable micelle-encapsulated quercetin. | 2012 | Int J Nanomedicine | pmid:22661886 |
Wink M et al. | Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents. | 2012 | Front Microbiol | pmid:22536197 |
Valcheva-Kuzmanova S et al. | Electron spin resonance measurement of radical scavenging activity of Aronia melanocarpa fruit juice. | 2012 | Pharmacogn Mag | pmid:22701293 |
Otles S and Yalcin B | Phenolic compounds analysis of root, stalk, and leaves of nettle. | 2012 | ScientificWorldJournal | pmid:22593694 |
Lee H et al. | Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22454682 |
Hidalgo M et al. | Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites. | 2012 | Genes Nutr | pmid:22218934 |
De Rosso M et al. | Study of anthocyanic profiles of twenty-one hybrid grape varieties by liquid chromatography and precursor-ion mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22688043 |
Kamonpatana K et al. | Susceptibility of anthocyanins to ex vivo degradation in human saliva. | 2012 | Food Chem | pmid:22868153 |
Zhu L et al. | Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. | 2012 | Int J Mol Sci | pmid:22489164 |
Zhu M et al. | Relationship between the composition of flavonoids and flower colors variation in tropical water lily (Nymphaea) cultivars. | 2012 | PLoS ONE | pmid:22485167 |
Payyavula RS et al. | Differential effects of environment on potato phenylpropanoid and carotenoid expression. | 2012 | BMC Plant Biol. | pmid:22429339 |
Poulose SM et al. | Anthocyanin-rich açai (Euterpe oleracea Mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. | 2012 | J. Agric. Food Chem. | pmid:22224493 |
Abraham SK et al. | Analysis of in vitro chemoprevention of genotoxic damage by phytochemicals, as single agents or as combinations. | 2012 | Mutat. Res. | pmid:22405976 |
Vauzour D | Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. | 2012 | Oxid Med Cell Longev | pmid:22701758 |
Kanazawa K et al. | Short photoirradiation induces flavonoid synthesis and increases its production in postharvest vegetables. | 2012 | J. Agric. Food Chem. | pmid:22506664 |
Ganugapati J et al. | Molecular docking studies of banana flower flavonoids as insulin receptor tyrosine kinase activators as a cure for diabetes mellitus. | 2012 | Bioinformation | pmid:22493522 |
Yoshimura Y et al. | Different localization patterns of anthocyanin species in the pericarp of black rice revealed by imaging mass spectrometry. | 2012 | PLoS ONE | pmid:22363605 |
Chagné D et al. | QTL and candidate gene mapping for polyphenolic composition in apple fruit. | 2012 | BMC Plant Biol. | pmid:22269060 |
Han Y et al. | Introduction of apple ANR genes into tobacco inhibits expression of both CHI and DFR genes in flowers, leading to loss of anthocyanin. | 2012 | J. Exp. Bot. | pmid:22238451 |
Woodward GM et al. | Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation. | 2011 | Mol Nutr Food Res | pmid:21370450 |
Nishizaki Y et al. | Structure of the acyl-glucose-dependent anthocyanin 5-O-glucosyltransferase gene in carnations and its disruption by transposable elements in some varieties. | 2011 | Mol. Genet. Genomics | pmid:22048706 |
Cuevas Montilla E et al. | Soluble and bound phenolic compounds in different Bolivian purple corn ( Zea mays L.) cultivars. | 2011 | J. Agric. Food Chem. | pmid:21639140 |
Sato M et al. | Tissue culture-induced flower-color changes in Saintpaulia caused by excision of the transposon inserted in the flavonoid 3', 5' hydroxylase (F3'5'H) promoter. | 2011 | Plant Cell Rep. | pmid:21293860 |
Reber JD et al. | Antioxidant capacity interactions and a chemical/structural model of phenolic compounds found in strawberries. | 2011 | Int J Food Sci Nutr | pmid:21385007 |
Zhao J et al. | MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. | 2011 | Plant Cell | pmid:21467581 |
Zamora-Ros R et al. | Estimation of the intake of anthocyanidins and their food sources in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. | 2011 | Br. J. Nutr. | pmid:21481290 |
Mahajan M et al. | Post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set. | 2011 | PLoS ONE | pmid:22145036 |
Gillman JD et al. | Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in brown hilum and brown seed coats. | 2011 | BMC Plant Biol. | pmid:22070454 |
Kovinich N et al. | Combined analysis of transcriptome and metabolite data reveals extensive differences between black and brown nearly-isogenic soybean (Glycine max) seed coats enabling the identification of pigment isogenes. | 2011 | BMC Genomics | pmid:21801362 |
Aizza LC and Dornelas MC | A genomic approach to study anthocyanin synthesis and flower pigmentation in passionflowers. | 2011 | J Nucleic Acids | pmid:21772993 |
Suzuki R et al. | Anthocyanidins-enriched bilberry extracts inhibit 3T3-L1 adipocyte differentiation via the insulin pathway. | 2011 | Nutr Metab (Lond) | pmid:21385419 |
Kortstee AJ et al. | Anthocyanin production as a potential visual selection marker during plant transformation. | 2011 | Transgenic Res. | pmid:21340526 |
Sharma M et al. | Identification of the pr1 gene product completes the anthocyanin biosynthesis pathway of maize. | 2011 | Genetics | pmid:21385724 |
Edirisinghe I et al. | Strawberry anthocyanin and its association with postprandial inflammation and insulin. | 2011 | Br. J. Nutr. | pmid:21736853 |
Wang Q et al. | Inhibitory effect of antioxidant extracts from various potatoes on the proliferation of human colon and liver cancer cells. | 2011 | Nutr Cancer | pmid:21888504 |
Choi JG et al. | In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. | 2011 | Evid Based Complement Alternat Med | pmid:19687188 |
Hämäläinen M et al. | Effects of flavonoids on prostaglandin E2 production and on COX-2 and mPGES-1 expressions in activated macrophages. | 2011 | Planta Med. | pmid:21341175 |
Korać RR and Khambholja KM | Potential of herbs in skin protection from ultraviolet radiation. | 2011 | Pharmacogn Rev | pmid:22279374 |
Alvarez-Suarez JM et al. | Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase. | 2011 | PLoS ONE | pmid:22016781 |
He Q et al. | Natural variation in petal color in Lycoris longituba revealed by anthocyanin components. | 2011 | PLoS ONE | pmid:21829604 |
Ohno S et al. | A bHLH transcription factor, DvIVS, is involved in regulation of anthocyanin synthesis in dahlia (Dahlia variabilis). | 2011 | J. Exp. Bot. | pmid:21765172 |
Telias A et al. | Apple skin patterning is associated with differential expression of MYB10. | 2011 | BMC Plant Biol. | pmid:21599973 |
Mirshekar M et al. | Chronic oral pelargonidin alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: involvement of oxidative stress. | 2010 Jan-Apr | Iran. Biomed. J. | pmid:20683496 |
BuendÃa B et al. | HPLC-MS analysis of proanthocyanidin oligomers and other phenolics in 15 strawberry cultivars. | 2010 | J. Agric. Food Chem. | pmid:20038100 |
Yen JH et al. | Glycine tomentella Hayata inhibits IL-1β and IL-6 production, inhibits MMP-9 activity, and enhances RAW264.7 macrophage clearance of apoptotic cells. | 2010 | J. Biomed. Sci. | pmid:21054849 |
Tamura S et al. | Six new acylated anthocyanins from red radish (Raphanus sativus). | 2010 | Chem. Pharm. Bull. | pmid:20823613 |
Lopes-Lutz D et al. | Characterization and quantification of polyphenols in Amazon grape (Pourouma cecropiifolia Martius). | 2010 | Molecules | pmid:21116224 |
Chiu LW et al. | The purple cauliflower arises from activation of a MYB transcription factor. | 2010 | Plant Physiol. | pmid:20855520 |
Tanaka Y et al. | Flower color modification by engineering of the flavonoid biosynthetic pathway: practical perspectives. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20834175 |