Pelargonidin

Pelargonidin is a lipid of Polyketides (PK) class. The involved functions are known as Uptake, Intestinal Absorption, glucose uptake, Process and Metabolic Inhibition. Pelargonidin often locates in Serosal, Mucous Membrane, brush border membrane, Membrane and Cell surface. The associated genes with Pelargonidin are SLC5A1 gene, SLC2A2 gene, Homologous Gene, F3 gene and CRSP3 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Pelargonidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pelargonidin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pelargonidin

MeSH term MeSH ID Detail
Cystitis D003556 23 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Pelargonidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pelargonidin?

Related references are published most in these journals:

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What functions are associated with Pelargonidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pelargonidin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pelargonidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pelargonidin?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Pelargonidin

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Authors Title Published Journal PubMed Link
Łata E et al. Vulnerability of anthocyanins to the components of a thin-layer chromatographic system and comprehensive screening of anthocyanes in alimentary products. 2018 J Chromatogr A pmid:30150119
González-Barrio R et al. Chemical composition of the edible flowers, pansy (Viola wittrockiana) and snapdragon (Antirrhinum majus) as new sources of bioactive compounds. 2018 Food Chem pmid:29478556
Xu Y et al. Pelargonidin-3-O-rutinoside as a novel α-glucosidase inhibitor for improving postprandial hyperglycemia. 2018 Chem. Commun. (Camb.) pmid:30394469
Zhang Y et al. Effect of Red and Blue Light on Anthocyanin Accumulation and Differential Gene Expression in Strawberry (Fragaria × ananassa). 2018 Molecules pmid:29614032
Oancea AM et al. The kinetics of thermal degradation of polyphenolic compounds from elderberry ( Sambucus nigra L.) extract. 2018 Food Sci Technol Int pmid:29409346
Xie S et al. Reduction of Dihydrokaempferol by Vitis vinfera Dihydroflavonol 4-Reductase to Produce Orange Pelargonidin-Type Anthocyanins. 2018 J. Agric. Food Chem. pmid:29554804
Xu W et al. Characterization of anthocyanins in the hybrid progenies derived from Iris dichotoma and I. domestica by HPLC-DAD-ESI/MS analysis. 2018 Phytochemistry pmid:29550699
Yari A and Rashnoo S Optimization of a new method for extraction of cyanidin chloride and pelargonidin chloride anthocyanins with magnetic solid phase extraction and determination in fruit samples by HPLC with central composite design. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28987497
Bashandy H and Teeri TH Genetically engineered orange petunias on the market. 2017 Planta pmid:28647812
Kurka O et al. Semisynthesis and spectral characterization of 5-methylpyranopelargonidin and 4-methylfuropelargonidin and their separation and detection in strawberry fruit wine. 2017 J Chromatogr A pmid:28648259
Samadder A et al. Nano-Pelargonidin Protects Hyperglycemic-Induced L6 Cells against Mitochondrial Dysfunction. 2017 Planta Med. pmid:28073120
Jeong S et al. Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses. 2017 Can. J. Physiol. Pharmacol. pmid:28060523
Lee IC and Bae JS Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses. 2017 Arch. Pharm. Res. pmid:27826751
Karthi N et al. Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach. 2017 Comput Biol Chem pmid:28950208
Łata E et al. Novel thin-layer chromatographic method of screening the anthocyanes containing alimentary products and precautions taken at the method development step. 2017 J Chromatogr A pmid:29173954
Servick K The strange case of the orange petunias. 2017 Science pmid:28546164
Dimitrić Marković JM et al. Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms. 2017 Food Chem pmid:27719933
Nankar AN et al. Quantitative and qualitative evaluation of kernel anthocyanins from southwestern United States blue corn. 2016 J. Sci. Food Agric. pmid:26879128
Min G et al. Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. 2016 Arch. Pharm. Res. pmid:27778275
Sohanaki H et al. Pelargonidin improves memory deficit in amyloid β25-35 rat model of Alzheimer's disease by inhibition of glial activation, cholinesterase, and oxidative stress. 2016 Biomed. Pharmacother. pmid:27470554
Müller-Maatsch J et al. Co-pigmentation of pelargonidin derivatives in strawberry and red radish model solutions by the addition of phenolic fractions from mango peels. 2016 Food Chem pmid:27451227
Arroyo-Maya IJ et al. Characterization of flavonoid-protein interactions using fluorescence spectroscopy: Binding of pelargonidin to dairy proteins. 2016 Food Chem pmid:27451201
Kang H et al. Suppressive Effects of Pelargonidin on Endothelial Protein C Receptor Shedding via the Inhibition of TACE Activity and MAP Kinases. 2016 Am. J. Chin. Med. pmid:27222063
Dhivya S et al. Impact of Anthocyanidins on Mitoxantrone-Induced Cytotoxicity and Genotoxicity: An In Vitro and In Vivo Analysis. 2016 Integr Cancer Ther pmid:27146128
Samadder A et al. Nanopharmaceutical approach using pelargonidin towards enhancement of efficacy for prevention of alloxan-induced DNA damage in L6 cells via activation of PARP and p53. 2016 Environ. Toxicol. Pharmacol. pmid:26943895
Park E et al. A dose-response evaluation of freeze-dried strawberries independent of fiber content on metabolic indices in abdominally obese individuals with insulin resistance in a randomized, single-blinded, diet-controlled crossover trial. 2016 Mol Nutr Food Res pmid:26842771
Ku SK et al. Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. 2016 Arch. Pharm. Res. pmid:26762345
Chen W et al. Protective effect of wild raspberry (Rubus hirsutus Thunb.) extract against acrylamide-induced oxidative damage is potentiated after simulated gastrointestinal digestion. 2016 Food Chem pmid:26593576
Espin S et al. Phenolic composition and antioxidant capacity of yellow and purple-red Ecuadorian cultivars of tree tomato (Solanum betaceum Cav.). 2016 Food Chem pmid:26471655
Sohanaki H et al. Pelargonidin Improves Passive Avoidance Task Performance in a Rat Amyloid Beta25-35 Model of Alzheimer's Disease Via Estrogen Receptor Independent Pathways. 2016 Acta Med Iran pmid:27309265
Park CH et al. Metabolic Profiling and Antioxidant Assay of Metabolites from Three Radish Cultivars (Raphanus sativus). 2016 Molecules pmid:26828471
Warskulat AC et al. Unprecedented Utilization of Pelargonidin and Indole for the Biosynthesis of Plant Indole Alkaloids. 2016 Chembiochem pmid:26670055
Yıldırım S et al. Fast determination of anthocyanins and free pelargonidin in fruits, fruit juices, and fruit wines by high-performance liquid chromatography using a core-shell column. 2016 J Sep Sci pmid:27550473
Lai YS et al. The Dark-Purple Tea Cultivar 'Ziyan' Accumulates a Large Amount of Delphinidin-Related Anthocyanins. 2016 J. Agric. Food Chem. pmid:26996195
Riha J et al. Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes. 2015 Food Funct pmid:25578040
Lim A et al. Potential natural sensitizers extracted from the skin of Canarium odontophyllum fruits for dye-sensitized solar cells. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25541396
Junqueira-Gonçalves MP et al. Isolation and characterization of phenolic compounds and anthocyanins from Murta (Ugni molinae Turcz.) fruits. Assessment of antioxidant and antibacterial activity. 2015 Molecules pmid:25838172
Khandelwal N and Abraham SK Protective effects of common anthocyanidins against genotoxic damage induced by chemotherapeutic drugs in mice. 2014 Planta Med. pmid:25184891
Zhu Y et al. Molecular cloning and functional characterization of the anthocyanidin reductase gene from Vitis bellula. 2014 Planta pmid:24880552
Khandelwal N and Abraham SK Intake of anthocyanidins pelargonidin and cyanidin reduces genotoxic stress in mice induced by diepoxybutane, urethane and endogenous nitrosation. 2014 Environ. Toxicol. Pharmacol. pmid:24642102
Somerset S and Papier K A food frequency questionnaire validated for estimating dietary flavonoid intake in an Australian population. 2014 Nutr Cancer pmid:25207829
Miosic S et al. Dihydroflavonol 4-reductase genes encode enzymes with contrasting substrate specificity and show divergent gene expression profiles in Fragaria species. 2014 PLoS ONE pmid:25393679
Lin YC et al. Protective effect of anthocyanidins against sodium dithionite-induced hypoxia injury in C6 glial cells. 2014 J. Agric. Food Chem. pmid:24845373
Son JE et al. Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. 2014 Biochem. Pharmacol. pmid:24582770
Lee MJ et al. Characterization and quantitation of anthocyanins in purple-fleshed sweet potatoes cultivated in Korea by HPLC-DAD and HPLC-ESI-QTOF-MS/MS. 2013 J. Agric. Food Chem. pmid:23464823
Ichiyanagi T et al. Structural elucidation and biological fate of two glucuronyl metabolites of pelargonidin 3-O-β-D-glucopyranoside in rats. 2013 J. Agric. Food Chem. pmid:23256460
Kamenickova A et al. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. 2013 Toxicol. Lett. pmid:23735880
Kamenickova A et al. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. 2013 Toxicol. Lett. pmid:23419638
Tatsuzawa F 7-O-methylpelargonidin glycosides from the pale red flowers of Catharanthus roseus. 2013 Nat Prod Commun pmid:24079176
Vodopivec BM et al. Differences in the structure of anthocyanins from the two amphibious plants, Lobelia cardinalis and Nesaea crassicaulis. 2013 Nat. Prod. Res. pmid:22694738