Pelargonidin

Pelargonidin is a lipid of Polyketides (PK) class. The involved functions are known as Uptake, Intestinal Absorption, glucose uptake, Process and Metabolic Inhibition. Pelargonidin often locates in Serosal, Mucous Membrane, brush border membrane, Membrane and Cell surface. The associated genes with Pelargonidin are SLC5A1 gene, SLC2A2 gene, Homologous Gene, F3 gene and CRSP3 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Pelargonidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pelargonidin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pelargonidin

MeSH term MeSH ID Detail
Cystitis D003556 23 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Pelargonidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pelargonidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pelargonidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pelargonidin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pelargonidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pelargonidin?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Pelargonidin

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Authors Title Published Journal PubMed Link
Zhang Y et al. Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties. 2008 J. Agric. Food Chem. pmid:18211028
Tulio AZ et al. Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidants in black raspberry. 2008 J. Agric. Food Chem. pmid:18290621
Yan Y et al. High-yield anthocyanin biosynthesis in engineered Escherichia coli. 2008 Biotechnol. Bioeng. pmid:18023053
Hämäläinen M et al. Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. 2007 Mediators Inflamm. pmid:18274639
Omoigui S The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. 2007 Immun Ageing pmid:17374166
Matsufuji H et al. Stability to light, heat, and hydrogen peroxide at different pH values and DPPH radical scavenging activity of acylated anthocyanins from red radish extract. 2007 J. Agric. Food Chem. pmid:17394340
Hernanz D et al. Assessment of the differences in the phenolic composition of five strawberry cultivars (Fragaria x ananassa Duch.) grown in two different soilless systems. 2007 J. Agric. Food Chem. pmid:17279770
Nicoué EE et al. Anthocyanins in wild blueberries of Quebec: extraction and identification. 2007 J. Agric. Food Chem. pmid:17579428
Felgines C et al. Strawberry pelargonidin glycosides are excreted in urine as intact glycosides and glucuronidated pelargonidin derivatives in rats. 2007 Br. J. Nutr. pmid:17559698
Stewart D et al. Metabolomic approach to identifying bioactive compounds in berries: advances toward fruit nutritional enhancement. 2007 Mol Nutr Food Res pmid:17492796
Aaby K et al. Characterization of phenolic compounds in strawberry (Fragaria x ananassa) fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity. 2007 J. Agric. Food Chem. pmid:17472391
Bakowska-Barczak AM et al. Survey of bioactive components in Western Canadian berries. 2007 Can. J. Physiol. Pharmacol. pmid:18066116
Hosseinian FS and Beta T Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries. 2007 J. Agric. Food Chem. pmid:18052240
Jordheim M et al. Molar absorptivities and reducing capacity of pyranoanthocyanins and other anthocyanins. 2007 J. Agric. Food Chem. pmid:18047275
Estévez L and Mosquera RA A density functional theory study on pelargonidin. 2007 J Phys Chem A pmid:17929785
de Brito ES et al. Anthocyanins present in selected tropical fruits: acerola, jambolão, jussara, and guajiru. 2007 J. Agric. Food Chem. pmid:17929888
Abraham SK et al. Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid. 2007 Mol Nutr Food Res pmid:17579891
Kern M et al. Limited stability in cell culture medium and hydrogen peroxide formation affect the growth inhibitory properties of delphinidin and its degradation product gallic acid. 2007 Mol Nutr Food Res pmid:17729219
Kottra G and Daniel H Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake. 2007 J. Pharmacol. Exp. Ther. pmid:17495124
Nakatsuka T et al. Production of red-flowered plants by genetic engineering of multiple flavonoid biosynthetic genes. 2007 Plant Cell Rep. pmid:17639403
Seitz C et al. Redirection of anthocyanin synthesis in Osteospermum hybrida by a two-enzyme manipulation strategy. 2007 Phytochemistry pmid:17286993
Grimplet J et al. Tissue-specific mRNA expression profiling in grape berry tissues. 2007 BMC Genomics pmid:17584945
Macz-Pop GA et al. New flavanol-anthocyanin condensed pigments and anthocyanin composition in guatemalan beans (Phaseolus spp.). 2006 J. Agric. Food Chem. pmid:16417317
Hjernø K et al. Down-regulation of the strawberry Bet v 1-homologous allergen in concert with the flavonoid biosynthesis pathway in colorless strawberry mutant. 2006 Proteomics pmid:16447153
El Mohsen MA et al. Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. 2006 Br. J. Nutr. pmid:16441916
Harnly JM et al. Flavonoid content of U.S. fruits, vegetables, and nuts. 2006 J. Agric. Food Chem. pmid:17177529
Rahman MM et al. Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. 2006 Free Radic. Res. pmid:17015281
Chirinos R et al. High-performance liquid chromatography with photodiode array detection (HPLC-DAD)/HPLC-mass spectrometry (MS) profiling of anthocyanins from Andean Mashua Tubers (Tropaeolum tuberosum Ruíz and Pavón) and their contribution to the overall antioxidant activity. 2006 J. Agric. Food Chem. pmid:16968067
Lamy S et al. Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. 2006 Carcinogenesis pmid:16308314
Abdel-Aal el-SM et al. Anthocyanin composition in black, blue, pink, purple, and red cereal grains. 2006 J. Agric. Food Chem. pmid:16787017
Espinosa-Alonso LG et al. Polyphenols in wild and weedy Mexican common beans (Phaseolus vulgaris L.). 2006 J. Agric. Food Chem. pmid:16756378
Wu X et al. Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption. 2006 J. Agric. Food Chem. pmid:16719536
Longo L and Vasapollo G Determination of anthocyanins in Ruscus aculeatus L. berries. 2005 J. Agric. Food Chem. pmid:15656691
Irani NG and Grotewold E Light-induced morphological alteration in anthocyanin-accumulating vacuoles of maize cells. 2005 BMC Plant Biol. pmid:15907203
Lorenc-Kukuła K et al. Ectopic expression of anthocyanin 5-o-glucosyltransferase in potato tuber causes increased resistance to bacteria. 2005 J. Agric. Food Chem. pmid:15656661
Garcia-Alonso M et al. Electron spin resonance spectroscopy studies on the free radical scavenging activity of wine anthocyanins and pyranoanthocyanins. 2005 Mol Nutr Food Res pmid:16254886
Mylnikov SV et al. Rubus fruit juices affect lipid peroxidation in a Drosophila melanogaster model in vivo. 2005 J. Agric. Food Chem. pmid:16190624
Longo L et al. Identification of anthocyanins in Rhamnus alaternus L. berries. 2005 J. Agric. Food Chem. pmid:15740065
Tian Q et al. Probing anthocyanin profiles in purple sweet potato cell line (Ipomoea batatas L. Cv. Ayamurasaki) by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry. 2005 J. Agric. Food Chem. pmid:16076141
Hou DX et al. Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. 2005 Biochem. Pharmacol. pmid:15963474
Habermeyer M et al. Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity. 2005 Chem. Res. Toxicol. pmid:16167831
Wu X and Prior RL Identification and characterization of anthocyanins by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in common foods in the United States: vegetables, nuts, and grains. 2005 J. Agric. Food Chem. pmid:15826066
Wu X and Prior RL Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries. 2005 J. Agric. Food Chem. pmid:15796599
Zhang Y et al. Human tumor cell growth inhibition by nontoxic anthocyanidins, the pigments in fruits and vegetables. 2005 Life Sci. pmid:15680311
Jayaprakasam B et al. Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. 2005 J. Agric. Food Chem. pmid:15631504
Shih PH et al. Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. 2005 Food Chem. Toxicol. pmid:15964118
Tian Q et al. Screening for anthocyanins using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry with precursor-ion analysis, product-ion analysis, common-neutral-loss analysis, and selected reaction monitoring. 2005 J Chromatogr A pmid:16395794
Nielsen AH et al. Flavonoids in flowers of 16 Kalanchoë blossfeldiana varieties. 2005 Phytochemistry pmid:16297414
Xie DY et al. Molecular and biochemical analysis of two cDNA clones encoding dihydroflavonol-4-reductase from Medicago truncatula. 2004 Plant Physiol. pmid:14976232
Wang L et al. Purification and cloning of a Chinese red radish peroxidase that metabolise pelargonidin and forms a gene family in Brassicaceae. 2004 Gene pmid:15588587