(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Dantas AM et al. Bioaccessibility of phenolic compounds in native and exotic frozen pulps explored in Brazil using a digestion model coupled with a simulated intestinal barrier. 2019 Food Chem pmid:30372928
Soares S et al. Effect of malvidin-3-glucoside and epicatechin interaction on their ability to interact with salivary proline-rich proteins. 2019 Food Chem pmid:30409602
Chen W et al. Effect of pH-shifting treatment on structural and functional properties of whey protein isolate and its interaction with (-)-epigallocatechin-3-gallate. 2019 Food Chem pmid:30372932
Owczarek A et al. A validated H qNMR method for direct and simultaneous quantification of esculin, fraxin and (-)-epicatechin in Hippocastani cortex. 2019 Talanta pmid:30348388
Schröder L et al. Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells. 2019 Oncol. Rep. pmid:30320348
Chen Y et al. Structure-activity relationship of procyanidins on advanced glycation end products formation and corresponding mechanisms. 2019 Food Chem pmid:30309598
Liu B and Yan W Lipophilization of EGCG and effects on antioxidant activities. 2019 Food Chem pmid:30309596
Wang S et al. Integration of (+)-catechin and β-sitosterol to achieve excellent radical-scavenging activity in emulsions. 2019 Food Chem pmid:30309587
Sonmezdag AS et al. Effect of hulling methods and roasting treatment on phenolic compounds and physicochemical properties of cultivars 'Ohadi' and 'Uzun' pistachios (Pistacia vera L.). 2019 Food Chem pmid:30309564
Wang Y et al. Novel insight into the role of withering process in characteristic flavor formation of teas using transcriptome analysis and metabolite profiling. 2019 Food Chem pmid:30309549
da Silva Sauthier MC et al. Screening of Mangifera indica L. functional content using PCA and neural networks (ANN). 2019 Food Chem pmid:30292356
Muñoz-Labrador A et al. Effects of high intensity ultrasound on disaggregation of a macromolecular procyanidin-rich fraction from Vitis vinifera L. seed extract and evaluation of its antioxidant activity. 2019 Ultrason Sonochem pmid:30219355
Cremonini E et al. (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. 2018 Redox Biol pmid:29154190
Zhang H et al. Effect of tea products on the in vitro enzymatic digestibility of starch. 2018 Food Chem pmid:29146347
Grant-Preece P et al. Impact of fluorescent lighting on the browning potential of model wine solutions containing organic acids and iron. 2018 Food Chem pmid:29146334
André DM et al. Epigallocatechin-3-gallate protects against the exacerbation of allergic eosinophilic inflammation associated with obesity in mice. 2018 Int. Immunopharmacol. pmid:30015241
Chirumbolo S Baicalin in flavocoxid may act against hepatitis B virus via a pro-inflammatory pathway. 2018 Inflamm. Res. pmid:29134230
Shin S et al. (-)-Epigallocatechin gallate derivatives reduce the expression of both urokinase plasminogen activator and plasminogen activator inhibitor-1 to inhibit migration, adhesion, and invasion of MDA-MB-231 cells. 2018 Phytother Res pmid:30009577
Vittorio O et al. Doxorubicin synergism and resistance reversal in human neuroblastoma BE(2)C cell lines: An in vitro study with dextran-catechin nanohybrids. 2018 Eur J Pharm Biopharm pmid:29129733
Zhao L et al. Study on interaction between human salivary α-amylase and sorghum procyanidin tetramer: Binding characteristics and structural analysis. 2018 Int. J. Biol. Macromol. pmid:30001600
Hassanein NMA et al. Chemopreventive effect of sulindac in combination with epigallocatechin gallate or kaempferol against 1,2-dimethyl hydrazine-induced preneoplastic lesions in rats: A Comparative Study. 2018 J. Biochem. Mol. Toxicol. pmid:29999212
Ueda-Wakagi M et al. Epigallocatechin gallate induces GLUT4 translocation in skeletal muscle through both PI3K- and AMPK-dependent pathways. 2018 Food Funct pmid:29998274
Koch W et al. Green Tea Quality Evaluation Based on Its Catechins and Metals Composition in Combination with Chemometric Analysis. 2018 Molecules pmid:29997337
Álvarez-Cilleros D et al. Protective effects of (-)-epicatechin and the colonic metabolite 3,4-dihydroxyphenylacetic acid against glucotoxicity-induced insulin signalling blockade and altered glucose uptake and production in renal tubular NRK-52E cells. 2018 Food Chem. Toxicol. pmid:29981789
Alejo-Armijo A et al. Synthesis and Evaluation of Antimicrobial and Antibiofilm Properties of A-Type Procyanidin Analogues against Resistant Bacteria in Food. 2018 J. Agric. Food Chem. pmid:29464945
Gao C et al. Development of a Thiolysis HPLC Method for the Analysis of Procyanidins in Cranberry Products. 2018 J. Agric. Food Chem. pmid:29430926
Hammerbacher A et al. Gallocatechin biosynthesis via a flavonoid 3',5'-hydroxylase is a defense response in Norway spruce against infection by the bark beetle-associated sap-staining fungus Endoconidiophora polonica. 2018 Phytochemistry pmid:29421514
Guo R et al. Epigallocatechin-3-gallate attenuates acute and chronic psoriatic itch in mice: Involvement of antioxidant, anti-inflammatory effects and suppression of ERK and Akt signaling pathways. 2018 Biochem. Biophys. Res. Commun. pmid:29402411
Li CF et al. Comprehensive Dissection of Metabolic Changes in Albino and Green Tea Cultivars. 2018 J. Agric. Food Chem. pmid:29397711
Gu L et al. In Vitro Bioavailability, Cellular Antioxidant Activity, and Cytotoxicity of β-Carotene-Loaded Emulsions Stabilized by Catechin-Egg White Protein Conjugates. 2018 J. Agric. Food Chem. pmid:29385797
Pollicino T et al. Flavocoxid exerts a potent antiviral effect against hepatitis B virus. 2018 Inflamm. Res. pmid:29018874
Jain P et al. Antimicrobial metabolites from Saraca asoca impairs the membrane transport system and quorum-sensing system in Pseudomonas aeruginosa. 2018 Arch. Microbiol. pmid:28993916
Xiong LG et al. Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans. 2018 Redox Biol pmid:28992589
Kaewprachu P et al. Characterization of fish myofibrillar protein film incorporated with catechin-Kradon extract. 2018 Int. J. Biol. Macromol. pmid:28987800
Kfoury N et al. Striking changes in tea metabolites due to elevational effects. 2018 Food Chem pmid:29853384
Ding S et al. Regulation of Immune Function by Polyphenols. 2018 J Immunol Res pmid:29850614
Kim JH et al. Inhibitory activity of (-)-epicatechin-3,5-O-digallate on α-glucosidase and in silico analysis. 2018 Int. J. Biol. Macromol. pmid:28958819
Di Gennaro P et al. Polyphenol Polymerization by an Alternative Oxidative Microbial Enzyme and Characterization of the Biological Activity of Oligomers. 2018 Biomed Res Int pmid:29850510
Micali A et al. Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity. 2018 Oxid Med Cell Longev pmid:29849925
Pervin M et al. Beneficial Effects of Green Tea Catechins on Neurodegenerative Diseases. 2018 Molecules pmid:29843466
Saeki K et al. In Vitro and In Silico Studies of the Molecular Interactions of Epigallocatechin-3--gallate (EGCG) with Proteins That Explain the Health Benefits of Green Tea. 2018 Molecules pmid:29843451
Wu H et al. Granny Smith apple procyanidin extract upregulates tight junction protein expression and modulates oxidative stress and inflammation in lipopolysaccharide-induced Caco-2 cells. 2018 Food Funct pmid:29808220
Li P et al. Metabolomic analysis reveals the composition differences in 13 Chinese tea cultivars of different manufacturing suitabilities. 2018 J. Sci. Food Agric. pmid:28734044
Escott C et al. Formation of polymeric pigments in red wines through sequential fermentation of flavanol-enriched musts with non-Saccharomyces yeasts. 2018 Food Chem pmid:28873660
Hayashi S et al. Investigation of color-deepening phenomenon in catechin-(4→8)-dimer as a proanthocyanidin model and structural determination of its derivatives by oxidation. 2018 Food Chem pmid:28873531
Kawakami W et al. Structural characterization of proanthocyanidins from adzuki seed coat. 2018 Food Chem pmid:28873529
Tang P et al. Honokiol nanoparticles based on epigallocatechin gallate functionalized chitin to enhance therapeutic effects against liver cancer. 2018 Int J Pharm pmid:29715531
Midttun HLE et al. Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells. 2018 Food Funct pmid:29714395
Wei S et al. Grape seed procyanidin extract inhibits adipogenesis and stimulates lipolysis of porcine adipocytes in vitro. 2018 J. Anim. Sci. pmid:29701782
Park JE et al. Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies. 2018 Molecules pmid:29690635
Rangi S et al. Evidence of similar protective effects afforded by white tea and its active component 'EGCG' on oxidative-stress mediated hepatic dysfunction during benzo(a)pyrene induced toxicity. 2018 Food Chem. Toxicol. pmid:29684493
Ma W et al. First evidence of epicatechin vanillate in grape seed and red wine. 2018 Food Chem pmid:29680058
Varela-Castillo O et al. Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach. 2018 Exp. Oncol. pmid:29600977
Chen Y et al. Occurrence of Functional Molecules in the Flowers of Tea (Camellia sinensis) Plants: Evidence for a Second Resource. 2018 Molecules pmid:29596355
Ni J et al. Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells. 2018 Molecules pmid:29596305
Imran A et al. Exploring the potential of black tea based flavonoids against hyperlipidemia related disorders. 2018 Lipids Health Dis pmid:29592809
Çelik EE and Gökmen V A study on interactions between the insoluble fractions of different coffee infusions and major cocoa free antioxidants and different coffee infusions and dark chocolate. 2018 Food Chem pmid:29571501
Stanley TH et al. Impact of roasting on the flavan-3-ol composition, sensory-related chemistry, and in vitro pancreatic lipase inhibitory activity of cocoa beans. 2018 Food Chem pmid:29571495
Seok JK et al. Punicalagin and (-)-Epigallocatechin-3-Gallate Rescue Cell Viability and Attenuate Inflammatory Responses of Human Epidermal Keratinocytes Exposed to Airborne Particulate Matter PM10. 2018 Skin Pharmacol Physiol pmid:29566388
Kim Y and Chang KO Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses. 2018 Virus Res. pmid:29382552
Dai T et al. Investigation the interaction between procyanidin dimer and α-amylase: Spectroscopic analyses and molecular docking simulation. 2018 Int. J. Biol. Macromol. pmid:29408006
Xu YQ et al. Quality development and main chemical components of Tieguanyin oolong teas processed from different parts of fresh shoots. 2018 Food Chem pmid:29407922
Sarmiento V et al. Synthesis of novel (-)-epicatechin derivatives as potential endothelial GPER agonists: Evaluation of biological effects. 2018 Bioorg. Med. Chem. Lett. pmid:29395974
Misaka S et al. Lack of pharmacokinetic interaction between fluvastatin and green tea in healthy volunteers. 2018 Eur. J. Clin. Pharmacol. pmid:29368187
Filippi A et al. Epigallocatechin-3-O-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines. 2018 Int J Food Sci Nutr pmid:29157036
Wang X et al. Physical properties and antioxidant capacity of chitosan/epigallocatechin-3-gallate films reinforced with nano-bacterial cellulose. 2018 Carbohydr Polym pmid:29111045
Vallejo-Ochoa J et al. Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2. 2018 Protoplasma pmid:29110138
Ruban VV et al. Inflammation and oxidative stress in corneal tissue in experimental keratitis due to Fusarium solani: Amelioration following topical therapy with voriconazole and epigallocatechin gallate. 2018 Mycoses pmid:29064157
Penta D et al. Epigenetics of skin cancer: Interventions by selected bioactive phytochemicals. 2018 Photodermatol Photoimmunol Photomed pmid:28976029
Zhang Y et al. Inhibition of Epigallocatechin-3-gallate/Protein Interaction by Methyl-β-cyclodextrin in Myofibrillar Protein Emulsion Gels under Oxidative Stress. 2018 J. Agric. Food Chem. pmid:29976058
Kellett ME et al. Modification of the cellular antioxidant activity (CAA) assay to study phenolic antioxidants in a Caco-2 cell line. 2018 Food Chem pmid:29120793
Rasheed Z et al. Epigallocatechin-3-O-gallate modulates global microRNA expression in interleukin-1β-stimulated human osteoarthritis chondrocytes: potential role of EGCG on negative co-regulation of microRNA-140-3p and ADAMTS5. 2018 Eur J Nutr pmid:28110479
Molinar-Toribio E et al. A high-fat high-sucrose diet affects the long-term metabolic fate of grape proanthocyanidins in rats. 2018 Eur J Nutr pmid:27730364
Abdеlaziz RR et al. Flavocoxid attenuates airway inflammation in ovalbumin-induced mouse asthma model. 2018 Chem. Biol. Interact. pmid:29986831
Gonzalez-Alfonso JL et al. Efficient α-Glucosylation of Epigallocatechin Gallate Catalyzed by Cyclodextrin Glucanotransferase from Thermoanaerobacter Species. 2018 J. Agric. Food Chem. pmid:29939740
Martins NO et al. Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba). 2018 BMC Complement Altern Med pmid:29866157
Rao S et al. Q-TOF LC/MS identification and UHPLC-Online ABTS antioxidant activity guided mapping of barley polyphenols. 2018 Food Chem pmid:30381193
Tsutsumi H et al. Chiral Recognition of Pharmaceuticals Having a Xanthine Skeleton by (-)-Epigallocatechin-3-O-gallate in Water. 2018 Chem. Pharm. Bull. pmid:29863063
Ruta LL et al. Epigallocatechin-3-O-gallate, the main green tea component, is toxic to Saccharomyces cerevisiae cells lacking the Fet3/Ftr1. 2018 Food Chem pmid:30381188
Fiori J et al. Chiral analysis of theanine and catechin in characterization of green tea by cyclodextrin-modified micellar electrokinetic chromatography and high performance liquid chromatography. 2018 J Chromatogr A pmid:29859684
Toro-Uribe S et al. Design, Fabrication, Characterization, and In Vitro Digestion of Alkaloid-, Catechin-, and Cocoa Extract-Loaded Liposomes. 2018 J. Agric. Food Chem. pmid:30353733
Luo Y et al. Molecular Characterization of WRKY Transcription Factors That Act as Negative Regulators of O-Methylated Catechin Biosynthesis in Tea Plants ( Camellia sinensis L.). 2018 J. Agric. Food Chem. pmid:30350966
Raekiansyah M et al. Inhibitory effect of the green tea molecule EGCG against dengue virus infection. 2018 Arch. Virol. pmid:29429035
Zhang G et al. The application of pomelo peel as a carrier for adsorption of epigallocatechin-3-gallate. 2018 J. Sci. Food Agric. pmid:29393516
Venkatakrishnan K et al. Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea in a double-blind clinical trial. 2018 Food Funct pmid:29384173
Higashino Y et al. Regioselective Synthesis of Procyanidin B6, A 4-6-Condensed (+)-Catechin Dimer, by Intramolecular Condensation. 2018 Molecules pmid:29346322
Qin CY et al. Epigallocatechin gallate attenuates mitochondrial DNA-induced inflammatory damage in the development of ventilator-induced lung injury. 2018 Phytomedicine pmid:30195870
Mukherjee S et al. Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells. 2018 Molecules pmid:29346317
Lai YH et al. Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice. 2018 BMC Complement Altern Med pmid:30189898
Wyganowska-ÅšwiÄ…tkowska M et al. Can EGCG Alleviate Symptoms of Down Syndrome by Altering Proteolytic Activity? 2018 Int J Mol Sci pmid:29342922
Jan S et al. Effect of environmental variables on phytonutrients of Origanum vulgare L. in the sub-humid region of the northwestern Himalayas. 2018 Environ Monit Assess pmid:30187208
Qin FY et al. Two Novel Proline-Containing Catechin Glucoside from Water-Soluble Extract of Codonopsis pilosula. 2018 Molecules pmid:29337873
Li X et al. (-)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice. 2018 Food Funct pmid:30183039
Gao X et al. Phytochemicals, Anti-Inflammatory, Antiproliferative, and Methylglyoxal Trapping Properties of Zijuan Tea. 2018 J. Food Sci. pmid:29337349
Kim KJ et al. Oligonol prevented the relapse of dextran sulfate sodium-ulcerative colitis through enhancing NRF2-mediated antioxidative defense mechanism. 2018 J. Physiol. Pharmacol. pmid:30149369
Zhang G and Zhang J Enhanced oral bioavailability of EGCG using pH-sensitive polymeric nanoparticles: characterization and in vivo investigation on nephrotic syndrome rats. 2018 Drug Des Devel Ther pmid:30147298
Gu M et al. Epigallocatechin Gallate Attenuates Bladder Dysfunction via Suppression of Oxidative Stress in a Rat Model of Partial Bladder Outlet Obstruction. 2018 Oxid Med Cell Longev pmid:30140361
Barbosa S et al. Detection and Quantitation of Frauds in the Authentication of Cranberry-Based Extracts by UHPLC-HRMS (Orbitrap) Polyphenolic Profiling and Multivariate Calibration Methods. 2018 J. Agric. Food Chem. pmid:30130108
Liu B et al. Phytochemical analysis and antibacterial activity of methanolic extract of Bergenia purpurascens against common respiratory infection causing bacterial species in vitro and in neonatal rats. 2018 Microb. Pathog. pmid:29366865
Chung JO et al. Quercetin and fisetin enhanced the small intestine cellular uptake and plasma levels of epi-catechins in in vitro and in vivo models. 2018 Food Funct pmid:29168878