| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Critchfield JW et al. | Inhibition of HIV activation in latently infected cells by flavonoid compounds. | 1996 | AIDS Res. Hum. Retroviruses | pmid:8825617 |
| Yang J et al. | Vaginal gel formulation based on theaflavin derivatives as a microbicide to prevent HIV sexual transmission. | 2012 | AIDS Res. Hum. Retroviruses | pmid:22867271 |
| Abou-Agag LH et al. | Polyphyenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells. | 2001 | Alcohol. Clin. Exp. Res. | pmid:11236827 |
| Long L et al. | The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model. | 2010 | Alcohol. Clin. Exp. Res. | pmid:20659071 |
| Yee YK and Koo MW | Anti-Helicobacter pylori activity of Chinese tea: in vitro study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10792128 |
| Muñoz-López F | Green tea for everything? | 2004 Jan-Feb | Allergol Immunopathol (Madr) | pmid:14980188 |
| Maeda-Yamamoto M et al. | The efficacy of early treatment of seasonal allergic rhinitis with benifuuki green tea containing O-methylated catechin before pollen exposure: an open randomized study. | 2009 | Allergol Int | pmid:19542766 |
| Masuda S et al. | 'Benifuuki' green tea containing o-methylated catechin reduces symptoms of Japanese cedar pollinosis: a randomized, double-blind, placebo-controlled trial. | 2014 | Allergol Int | pmid:24561771 |
| Hsu CH et al. | Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. | 2011 | Altern Med Rev | pmid:21649457 |
| Brown MD | Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer. | 1999 | Altern Med Rev | pmid:10559550 |
| Patrick L | Hepatitis C: epidemiology and review of complementary/alternative medicine treatments. | 1999 | Altern Med Rev | pmid:10468647 |
| Kidd PM | Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. | 2009 | Altern Med Rev | pmid:19803548 |
| Hoy SM | Polyphenon E 10% ointment: in immunocompetent adults with external genital and perianal warts. | 2012 | Am J Clin Dermatol | pmid:22667336 |
| Rigelsky JM and Sweet BV | Hawthorn: pharmacology and therapeutic uses. | 2002 | Am J Health Syst Pharm | pmid:11887407 |
| Claus-Walker J et al. | Connective tissue turnover in quadriplegia. | 1982 | Am J Phys Med | pmid:7091304 |
| Chang JH et al. | Dietary polyphenols affect MUC5AC expression and ciliary movement in respiratory cells and nasal mucosa. | 2010 Mar-Apr | Am J Rhinol Allergy | pmid:20338103 |
| Losso JN et al. | Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. | Am J Ther | pmid:28901958 | |
| Moghadamtousi SZ et al. | Phytochemistry and biology of Loranthus parasiticus Merr, a commonly used herbal medicine. | 2014 | Am. J. Chin. Med. | pmid:24467533 |
| Luo D et al. | Effect of epigallocatechingallate on ultraviolet B-induced photo-damage in keratinocyte cell line. | 2006 | Am. J. Chin. Med. | pmid:17080554 |
| Thichanpiang P and Wongprasert K | Green tea polyphenol epigallocatechin-3-gallate attenuates TNF-α-induced intercellular adhesion molecule-1 expression and monocyte adhesion to retinal pigment epithelial cells. | 2015 | Am. J. Chin. Med. | pmid:25644976 |
| Yu SJ et al. | Epigallocatechin-3-gallate Prevents Triptolide-Induced Hepatic Injury by Restoring the Th17/T Balance in Mice. | 2016 | Am. J. Chin. Med. | pmid:27744729 |
| Yu FR et al. | Effects of a flavonoid extract from Cynomorium songaricum on the swimming endurance of rats. | 2010 | Am. J. Chin. Med. | pmid:20128045 |
| Syed Hussein SS et al. | (+)-Catechin Attenuates NF-κB Activation Through Regulation of Akt, MAPK, and AMPK Signaling Pathways in LPS-Induced BV-2 Microglial Cells. | 2015 | Am. J. Chin. Med. | pmid:26227399 |
| Hisamura F et al. | Synergistic effect of green tea polyphenols on their protection against FK506-induced cytotoxicity in renal cells. | 2008 | Am. J. Chin. Med. | pmid:18543393 |
| Asadi S et al. | Chemical composition analysis, antioxidant, antiglycating activities and neuroprotective effects of S. choloroleuca, S. mirzayanii and S. santolinifolia from Iran. | 2011 | Am. J. Chin. Med. | pmid:21598426 |
| Liu S et al. | PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells. | 2013 | Am. J. Chin. Med. | pmid:23711146 |
| Kim MJ et al. | (-)-Epigallocatechin-3-gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt. | 2009 | Am. J. Chin. Med. | pmid:19655410 |
| Chen YZ and Ung CY | Computer automated prediction of potential therapeutic and toxicity protein targets of bioactive compounds from Chinese medicinal plants. | 2002 | Am. J. Chin. Med. | pmid:12067089 |
| Liao JC et al. | Chemical compositions, anti-inflammatory, antiproliferative and radical-scavenging activities of Actinidia callosa var. ephippioides. | 2012 | Am. J. Chin. Med. | pmid:22928834 |
| Bae UJ et al. | Epigallocatechin-3-Gallate-Rich Green Tea Extract Ameliorates Fatty Liver and Weight Gain in Mice Fed a High Fat Diet by Activating the Sirtuin 1 and AMP Activating Protein Kinase Pathway. | 2018 | Am. J. Chin. Med. | pmid:29595075 |
| Rhyu DY et al. | Active compounds isolated from traditional Chinese prescription Wen-Pi-Tang protecting against peroxynitrite-induced LLC-PK(1) cell damage. | 2008 | Am. J. Chin. Med. | pmid:18711772 |
| Rodriguez M et al. | Letter to the editor: Panaxadiol's anticancer activity is enhanced by epicatechin. | 2010 | Am. J. Chin. Med. | pmid:21061473 |
| Shimada Y et al. | Protective effect of phenolic compounds isolated from the hooks and stems of Uncaria sinensis on glutamate-induced neuronal death. | 2001 | Am. J. Chin. Med. | pmid:11321476 |
| Wang S et al. | Epigallocatechin-3-gallate potentiates the effect of curcumin in inducing growth inhibition and apoptosis of resistant breast cancer cells. | 2014 | Am. J. Chin. Med. | pmid:25242081 |
| Lao W et al. | Comparison of Cytotoxicity and the Anti-Adipogenic Effect of Green Tea Polyphenols with Epigallocatechin-3-Gallate in 3T3-L1 Preadipocytes. | 2015 | Am. J. Chin. Med. | pmid:26446202 |
| Dower JI et al. | Reply to H Schroeter et al. | 2015 | Am. J. Clin. Nutr. | pmid:26429944 |
| Schroeter H et al. | Is this the end of (-)-epicatechin, or not? New study highlights the complex challenges associated with research into the cardiovascular health benefits of bioactive food constituents. | 2015 | Am. J. Clin. Nutr. | pmid:26429943 |
| Koga T and Meydani M | Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells. | 2001 | Am. J. Clin. Nutr. | pmid:11333849 |
| Samavat H et al. | Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial. | 2016 | Am. J. Clin. Nutr. | pmid:27806972 |
| Mähler A et al. | Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial. | 2015 | Am. J. Clin. Nutr. | pmid:25733633 |
| Frankenfeld CL et al. | Dietary flavonoid intake and non-Hodgkin lymphoma risk. | 2008 | Am. J. Clin. Nutr. | pmid:18469269 |
| Henning SM et al. | Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. | 2004 | Am. J. Clin. Nutr. | pmid:15585768 |
| Lorenz M | Cellular targets for the beneficial actions of tea polyphenols. | 2013 | Am. J. Clin. Nutr. | pmid:24172299 |
| Ottaviani JI et al. | Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. | 2012 | Am. J. Clin. Nutr. | pmid:22378733 |
| Kao YH et al. | Modulation of obesity by a green tea catechin. | 2000 | Am. J. Clin. Nutr. | pmid:11063454 |
| Mukhtar H and Ahmad N | Tea polyphenols: prevention of cancer and optimizing health. | 2000 | Am. J. Clin. Nutr. | pmid:10837321 |
| De Gottardi A et al. | Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial. | 2012 | Am. J. Clin. Nutr. | pmid:22811444 |
| Farrar MD et al. | A randomized controlled trial of green tea catechins in protection against ultraviolet radiation-induced cutaneous inflammation. | 2015 | Am. J. Clin. Nutr. | pmid:26178731 |
| Clifford MN et al. | Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols. | 2013 | Am. J. Clin. Nutr. | pmid:24172307 |
| Hursel R and Westerterp-Plantenga MS | Catechin- and caffeine-rich teas for control of body weight in humans. | 2013 | Am. J. Clin. Nutr. | pmid:24172301 |
| Lambert JD | Does tea prevent cancer? Evidence from laboratory and human intervention studies. | 2013 | Am. J. Clin. Nutr. | pmid:24172300 |
| Pignatelli P et al. | The flavonoids quercetin and catechin synergistically inhibit platelet function by antagonizing the intracellular production of hydrogen peroxide. | 2000 | Am. J. Clin. Nutr. | pmid:11063442 |
| Ellinger S et al. | Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach. | 2012 | Am. J. Clin. Nutr. | pmid:22552030 |
| Wan Y et al. | Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans. | 2001 | Am. J. Clin. Nutr. | pmid:11684527 |
| Greenberg JA et al. | Epicatechin, procyanidins, cocoa, and appetite: a randomized controlled trial. | 2016 | Am. J. Clin. Nutr. | pmid:27510533 |
| Phung OJ et al. | Effect of green tea catechins with or without caffeine on anthropometric measures: a systematic review and meta-analysis. | 2010 | Am. J. Clin. Nutr. | pmid:19906797 |
| Watanabe I et al. | Green tea and death from pneumonia in Japan: the Ohsaki cohort study. | 2009 | Am. J. Clin. Nutr. | pmid:19625686 |
| Mullen W et al. | Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. | 2009 | Am. J. Clin. Nutr. | pmid:19403635 |
| Crozier A | Absorption, metabolism, and excretion of (-)-epicatechin in humans: an evaluation of recent findings. | 2013 | Am. J. Clin. Nutr. | pmid:23985809 |
| Hughes LA et al. | Higher dietary flavone, flavonol, and catechin intakes are associated with less of an increase in BMI over time in women: a longitudinal analysis from the Netherlands Cohort Study. | 2008 | Am. J. Clin. Nutr. | pmid:18996871 |
| Schramm DD et al. | Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells. | 2001 | Am. J. Clin. Nutr. | pmid:11124747 |
| Weaver CM et al. | Botanicals for age-related diseases: from field to practice. | 2008 | Am. J. Clin. Nutr. | pmid:18258645 |
| Hsu SP et al. | Chronic green tea extract supplementation reduces hemodialysis-enhanced production of hydrogen peroxide and hypochlorous acid, atherosclerotic factors, and proinflammatory cytokines. | 2007 | Am. J. Clin. Nutr. | pmid:17991670 |
| Baba S et al. | Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans. | 2007 | Am. J. Clin. Nutr. | pmid:17344491 |
| Mulder TP et al. | Consumption of both black tea and green tea results in an increase in the excretion of hippuric acid into urine. | 2005 | Am. J. Clin. Nutr. | pmid:15640488 |
| Williamson G and Manach C | Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. | 2005 | Am. J. Clin. Nutr. | pmid:15640487 |
| Actis-Goretta L et al. | Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique. | 2013 | Am. J. Clin. Nutr. | pmid:23864538 |
| Nagao T et al. | Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. | 2005 | Am. J. Clin. Nutr. | pmid:15640470 |
| Scalbert A and Zamora-Ros R | Bridging evidence from observational and intervention studies to identify flavonoids most protective for human health. | 2015 | Am. J. Clin. Nutr. | pmid:25832341 |
| Donovan JL | Flavonoids and the risk of cardiovascular disease in women. | 2004 | Am. J. Clin. Nutr. | pmid:14985231 |
| Murphy KJ et al. | Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function. | 2003 | Am. J. Clin. Nutr. | pmid:12791625 |
| Rios LY et al. | Cocoa procyanidins are stable during gastric transit in humans. | 2002 | Am. J. Clin. Nutr. | pmid:12399286 |
| Ebeler SE et al. | Dietary catechin delays tumor onset in a transgenic mouse model. | 2002 | Am. J. Clin. Nutr. | pmid:12324302 |
| Holt RR et al. | Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa. | 2002 | Am. J. Clin. Nutr. | pmid:12324293 |
| Nestel PJ | How good is chocolate? | 2001 | Am. J. Clin. Nutr. | pmid:11684518 |
| Arts IC et al. | Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly Study. | 2001 | Am. J. Clin. Nutr. | pmid:11470725 |
| Chen JH et al. | Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide-derived prooxidants. | 2004 | Am. J. Clin. Nutr. | pmid:15321817 |
| Yoneshiro T et al. | Tea catechin and caffeine activate brown adipose tissue and increase cold-induced thermogenic capacity in humans. | 2017 | Am. J. Clin. Nutr. | pmid:28275131 |
| Cassidy A et al. | Habitual intake of flavonoid subclasses and incident hypertension in adults. | 2011 | Am. J. Clin. Nutr. | pmid:21106916 |
| Dower JI et al. | Dietary epicatechin intake and 25-y risk of cardiovascular mortality: the Zutphen Elderly Study. | 2016 | Am. J. Clin. Nutr. | pmid:27225434 |
| Dower JI et al. | Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial. | 2015 | Am. J. Clin. Nutr. | pmid:25934864 |
| Hursel R and Westerterp-Plantenga MS | Green tea catechin plus caffeine supplementation to a high-protein diet has no additional effect on body weight maintenance after weight loss. | 2009 | Am. J. Clin. Nutr. | pmid:19176733 |
| Zheng XX et al. | Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. | 2013 | Am. J. Clin. Nutr. | pmid:23426037 |
| Most J et al. | Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. | 2016 | Am. J. Clin. Nutr. | pmid:27194304 |
| Bell JR et al. | (+)-Catechin in human plasma after ingestion of a single serving of reconstituted red wine. | 2000 | Am. J. Clin. Nutr. | pmid:10617953 |
| Loke WM et al. | Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. | 2008 | Am. J. Clin. Nutr. | pmid:18842789 |
| Dulloo AG et al. | Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. | 1999 | Am. J. Clin. Nutr. | pmid:10584049 |
| Sansone R et al. | Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies. | 2017 | Am. J. Clin. Nutr. | pmid:28003203 |
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| Geybels MS et al. | Dietary flavonoid intake, black tea consumption, and risk of overall and advanced stage prostate cancer. | 2013 | Am. J. Epidemiol. | pmid:23722011 |
| Butler LM et al. | Urinary biomarkers of catechins and risk of hepatocellular carcinoma in the Shanghai Cohort Study. | 2015 | Am. J. Epidemiol. | pmid:25713334 |
| DiCesare D et al. | A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico. | 2002 | Am. J. Gastroenterol. | pmid:12385443 |
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| Vischini G et al. | Increased plasma levels of tacrolimus after ingestion of green tea. | 2011 | Am. J. Kidney Dis. | pmid:21787983 |
| Chrubasik S | Evidence of the effectiveness of hawthorn extract. | 2003 | Am. J. Med. | pmid:14599643 |
| Abd El-Rahman SS et al. | Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats. | 2017 | Am. J. Med. Sci. | pmid:28755734 |
| Yang P and Li H | Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation. | 2010 | Am. J. Obstet. Gynecol. | pmid:20417490 |
| Zhong J et al. | The green tea polyphenol EGCG alleviates maternal diabetes-induced neural tube defects by inhibiting DNA hypermethylation. | 2016 | Am. J. Obstet. Gynecol. | pmid:26979632 |
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(-)-Epicatechin
(-)-Epicatechin is a lipid of Polyketides (PK) class.
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