(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Xie D et al. (-)-Epigallocatechin-3-gallate protects cultured spiral ganglion cells from H2O2-induced oxidizing damage. 2004 Acta Otolaryngol. pmid:15224876
Kumar S et al. Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) Schrad. methanolic fruit extract. 2008 Acta Pharm pmid:18515231
Scalia S et al. In vivo human skin penetration of (-)-epigallocatechin-3-gallate from topical formulations. 2014 Acta Pharm pmid:24914725
Rudolfová P et al. Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro. 2014 Acta Pharm pmid:24914720
Siegers CP et al. Influence of dithiocarb, (+)-catechin and silybine on halothane hepatotoxicity in the hypoxic rat model. 1983 Acta Pharmacol Toxicol (Copenh) pmid:6312740
Wang JN et al. Antioxidant activity of polyphenols from seeds of Vitis amurensis in vitro. 2000 Acta Pharmacol. Sin. pmid:11360672
Huang Y et al. Role of endothelium/nitric oxide in vascular response to flavonoids and epicatechin. 2000 Acta Pharmacol. Sin. pmid:11603286
Chen ZY et al. Inhibitory effects of purified green tea epicatechins on contraction and proliferation of arterial smooth muscle cells. 2000 Acta Pharmacol. Sin. pmid:11501167
Su HF et al. Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms. 2016 Acta Pharmacol. Sin. pmid:26972494
Yang D et al. Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway. 2010 Acta Pharmacol. Sin. pmid:20644550
Ling JX et al. Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea. 2012 Acta Pharmacol. Sin. pmid:22941291
Zhen MC et al. Green tea polyphenol epigallocatechin-3-gallate suppresses rat hepatic stellate cell invasion by inhibition of MMP-2 expression and its activation. 2006 Acta Pharmacol. Sin. pmid:17112415
Han DW et al. Epigallocatechin-3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-κB in human dermal fibroblasts. 2011 Acta Pharmacol. Sin. pmid:21516136
Zhou F et al. Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. 2012 Acta Pharmacol. Sin. pmid:22101170
Jin J et al. Prostanoid EP1 receptor as the target of (-)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro. 2012 Acta Pharmacol. Sin. pmid:22555372
Chen ZY et al. (-)epicatechin induces and modulates endothelium-dependent relaxation in isolated rat mesenteric artery rings. 2002 Acta Pharmacol. Sin. pmid:12466059
Yang K and Chan CB Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on its antioxidant activity. 2018 Acta Pharmacol. Sin. pmid:29417944
Lu Y et al. Procyanidins from grape seeds protect against phorbol ester-induced oxidative cellular and genotoxic damage. 2004 Acta Pharmacol. Sin. pmid:15301744
Howells LM et al. Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals. 2007 Acta Pharmacol. Sin. pmid:17723163
Li C et al. Anti-influenza effect and action mechanisms of the chemical constituent gallocatechin-7-gallate from Pithecellobium clypearia Benth. 2018 Acta Pharmacol. Sin. pmid:29802302
Xu F and Zhen YS (-)-Epigallocatechin-3-gallate enhances anti-tumor effect of cytosine arabinoside on HL-60 cells. 2003 Acta Pharmacol. Sin. pmid:12546725
Sheng R et al. EGCG inhibits cardiomyocyte apoptosis in pressure overload-induced cardiac hypertrophy and protects cardiomyocytes from oxidative stress in rats. 2007 Acta Pharmacol. Sin. pmid:17241521
Gan L et al. Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice. 2015 Acta Pharmacol. Sin. pmid:25891086
Nair S et al. Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells. 2010 Acta Pharmacol. Sin. pmid:20729872
Yu DK et al. The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway. 2015 Acta Pharmacol. Sin. pmid:25832428
Nacerai H et al. GREEN TEA BEVERAGE AND EPIGALLOCATECIHIN GALLATE ATTENUATE NICOTINE CARDIOCYTOTOXICITY IN RAT. 2017 Acta Pol Pharm pmid:29474782
Rychlińska I and Gudej J Qualitative and quantitative chromatographic investigation of flavonoids in Pyrus communis L. flowers. Acta Pol Pharm pmid:12848372
Łuczaj W et al. Polyphenols action against oxidative stress formation in endothelial cells. 2009 Nov-Dec Acta Pol Pharm pmid:20050525
Chetia M and Das R Effect of (-)-epicatechin, a flavonoid on the NO and NOS activity of Raillietina echinobothrida. 2018 Acta Trop. pmid:29208358
Alcántara González J et al. Extragenital warts treated with sinecatechins ointment. 2015 Actas Dermosifiliogr pmid:25262363
Skrzydlewska E et al. Green tea as a potent antioxidant in alcohol intoxication. 2002 Addict Biol pmid:12126490
Chen D et al. EGCG, green tea polyphenols and their synthetic analogs and prodrugs for human cancer prevention and treatment. 2011 Adv Clin Chem pmid:21404918
Hosnuter M et al. The Protective Effects of Epigallocatechin Gallate Against Distant Organ Damage After Severe Skin Burns--Experimental Study Using a Rat Model of Thermal Trauma. Adv Clin Exp Med pmid:26467128
Shin YC et al. Hyaluronic Acid/PLGA Core/Shell Fiber Matrices Loaded with EGCG Beneficial to Diabetic Wound Healing. 2016 Adv Healthc Mater pmid:27805803
Pillai L et al. Flavocoxid, an anti-inflammatory agent of botanical origin, does not affect coagulation or interact with anticoagulation therapies. 2010 Adv Ther pmid:20556559
Tang LQ et al. Effects and mechanisms of catechin for adjuvant arthritis in rats. Adv Ther pmid:17660179
Levy R et al. Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis. 2010 Adv Ther pmid:20972845
Levy RM et al. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. 2010 Adv Ther pmid:20845002
Rizzi F and Bettuzzi S Clusterin (CLU) and prostate cancer. 2009 Adv. Cancer Res. pmid:19879420
Katunuma N et al. New apoptosis cascade mediated by lysosomal enzyme and its protection by epigallo-catechin gallate. 2004 Adv. Enzyme Regul. pmid:15581478
Narotzki B et al. Green tea and its major polyphenol EGCG increase the activity of oral peroxidases. 2013 Adv. Exp. Med. Biol. pmid:22836624
Shirakami Y et al. Catechins and Its Role in Chronic Diseases. 2016 Adv. Exp. Med. Biol. pmid:27771921
Andrich K and Bieschke J The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. 2015 Adv. Exp. Med. Biol. pmid:26092630
Caruana M and Vassallo N Tea Polyphenols in Parkinson's Disease. 2015 Adv. Exp. Med. Biol. pmid:26092629
Weinstein B Relevance of the concept of oncogene addiction to hormonal carcinogenesis and molecular targeting in cancer prevention and therapy. 2008 Adv. Exp. Med. Biol. pmid:18497026
Kun L et al. Simultaneous determination of contents of three active components in Jiejia tincture by HPLC method. 2013 Afr J Tradit Complement Altern Med pmid:24311852
Doğan HH and Aydın S Determination of antimicrobial effect, antioxidant activity and phenolic contents of desert truffle in Turkey. 2013 Afr J Tradit Complement Altern Med pmid:24146501
Niu Y et al. The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats. 2013 Aging Cell pmid:23834676
Cameron AR et al. Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a. 2008 Aging Cell pmid:18005251
Fassina G et al. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent. 2002 AIDS pmid:11919502