(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Kanagaratnam R et al. An efflux pump (MexAB-OprM) of Pseudomonas aeruginosa is associated with antibacterial activity of Epigallocatechin-3-gallate (EGCG). 2017 Phytomedicine pmid:29157815
Fang R et al. Variation of theanine, phenolic, and methylxanthine compounds in 21 cultivars of Camellia sinensis harvested in different seasons. 2017 Food Chem pmid:27855934
Hu X et al. Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway. 2017 Acta Biomater pmid:27838465
Nacerai H et al. GREEN TEA BEVERAGE AND EPIGALLOCATECIHIN GALLATE ATTENUATE NICOTINE CARDIOCYTOTOXICITY IN RAT. 2017 Acta Pol Pharm pmid:29474782
Wang ZM et al. Polyphenol epigallocatechin-3-gallate alleviates high glucose-induced H9C2 cell damage through PI3K/Akt pathway. 2017 Eur Rev Med Pharmacol Sci pmid:29028073
Bhakta HK et al. Oligonol promotes glucose uptake by modulating the insulin signaling pathway in insulin-resistant HepG2 cells via inhibiting protein tyrosine phosphatase 1B. 2017 Arch. Pharm. Res. pmid:29027136
Pan JH et al. Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation. 2017 PLoS ONE pmid:29176803
Jansson T et al. Green Tea Polyphenols Decrease Strecker Aldehydes and Bind to Proteins in Lactose-Hydrolyzed UHT Milk. 2017 J. Agric. Food Chem. pmid:29119790
Jung ES et al. The green tea modulates large intestinal microbiome and exo/endogenous metabolome altered through chronic UVB-exposure. 2017 PLoS ONE pmid:29117187
Satonaka H et al. (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways. 2017 Anticancer Res. pmid:29061787
Downing LE et al. A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target-gene expression. 2017 Mol Nutr Food Res pmid:27624175
Mizuno M et al. Enhanced radical scavenging activity of a procyanidin B3 analogue comprised of a dimer of planar catechin. 2017 Bioorg. Med. Chem. Lett. pmid:29054360
Türközü D and Tek NA A minireview of effects of green tea on energy expenditure. 2017 Crit Rev Food Sci Nutr pmid:26091183
Yao S et al. Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN. 2017 Int. J. Oncol. pmid:28766684
Yamanaka D et al. Effects of epigallocatechin-3-gallate on systemic inflammation-induced cognitive dysfunction in aged rats. 2017 J Anesth pmid:28752431
Xue B et al. Effect of epigallocatechin gallate on growth performance and antioxidant capacity in heat-stressed broilers. 2017 Arch Anim Nutr pmid:28741959
Koutelidakis AE et al. Bioactivity of Epigallocatechin Gallate Nanoemulsions Evaluated in Mice Model. 2017 J Med Food pmid:28737454
Sakai G et al. Amplification by (‑)‑epigallocatechin gallate of prostaglandin F2α‑stimulated synthesis of osteoprotegerin in osteoblasts. 2017 Mol Med Rep pmid:28849144
Yamamoto N et al. Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways. 2017 Neuroscience pmid:28844000
Ahmed R et al. Molecular Mechanism for the (-)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers. 2017 J. Am. Chem. Soc. pmid:28841302
Pence BD et al. Long-term supplementation with EGCG and beta-alanine decreases mortality but does not affect cognitive or muscle function in aged mice. 2017 Exp. Gerontol. pmid:28818411
Ying L et al. (-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease. 2017 Clin. Exp. Pharmacol. Physiol. pmid:28815679
Chu YW et al. The cytotoxic mechanism of epigallocatechin gallate on proliferative HaCaT keratinocytes. 2017 J. Biomed. Sci. pmid:28810862
Tang L et al. Potential benefit of (-)-epigallocatechin-3-gallate for macrovascular complications in diabetes. 2017 Braz. J. Med. Biol. Res. pmid:28832766
Mohan T et al. Impact of EGCG Supplementation on the Progression of Diabetic Nephropathy in Rats: An Insight into Fibrosis and Apoptosis. 2017 J. Agric. Food Chem. pmid:28823168
Chen L et al. Therapeutic properties of green tea against environmental insults. 2017 J. Nutr. Biochem. pmid:27723473
Nie RZ et al. Comparison of disaggregative effect of A-type EGCG dimer and EGCG monomer on the preformed bovine insulin amyloid fibrils. 2017 Biophys. Chem. pmid:28818314
Ezgi Ünlü A et al. Investigation of a green process for the polymerization of catechin. 2017 Prep. Biochem. Biotechnol. pmid:28816607
Decroix L et al. Acute cocoa Flavanols intake has minimal effects on exercise-induced oxidative stress and nitric oxide production in healthy cyclists: a randomized controlled trial. 2017 J Int Soc Sports Nutr pmid:28811749
Zhao J et al. Metal chelator EGCG attenuates Fe(III)-induced conformational transition of α-synuclein and protects AS-PC12 cells against Fe(III)-induced death. 2017 J. Neurochem. pmid:28792609
Bhatt V et al. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS. 2017 J Pharm Biomed Anal pmid:27693952
Niu L et al. Reduction of oxidative damages induced by titanium dioxide nanoparticles correlates with induction of the Nrf2 pathway by GSPE supplementation in mice. 2017 Chem. Biol. Interact. pmid:28780322
Kim TE et al. Effect of epigallocatechin-3-gallate, major ingredient of green tea, on the pharmacokinetics of rosuvastatin in healthy volunteers. 2017 Drug Des Devel Ther pmid:28533679
Wong KC et al. (-)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro. 2017 Nutrients pmid:28531166
Patel S et al. Comparative Safety and Efficacy Profile of a Novel Oil in Water Vaccine Adjuvant Comprising Vitamins A and E and a Catechin in Protective Anti-Influenza Immunity. 2017 Nutrients pmid:28531130
Fu QY et al. Antidiabetic Effects of Tea. 2017 Molecules pmid:28531120
Guo Y et al. (-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease. 2017 Neuroreport pmid:28520620
Xie X et al. Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux. 2017 Nutrients pmid:28505110
Pons-Fuster López E et al. Potential chemotherapeutic effects of diosgenin, zoledronic acid and epigallocatechin-3-gallate on PE/CA-PJ15 oral squamous cancer cell line. 2017 Arch. Oral Biol. pmid:28641180
Caporaletti F et al. Hydrogen-Deuterium exchange kinetics in β-lactoglobulin (-)-epicatechin complexes studied by FTIR spectroscopy. 2017 Int. J. Biol. Macromol. pmid:28629860
Dettlaff K et al. Formulation and characterization of EGCG for the treatment of superficial bladder cancer. 2017 Int. J. Mol. Med. pmid:28627636
Kuroyanagi G et al. (-)-Epigallocatechin gallate synergistically potentiates prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts. 2017 Prostaglandins Other Lipid Mediat. pmid:28163121
Vázquez Cisneros LC et al. Effects of green tea and its epigallocatechin (EGCG) content on body weight and fat mass in humans: a systematic review 2017 Nutr Hosp pmid:28627214
de Souza-E-Silva CM et al. Effect of gels containing chlorhexidine or epigallocatechin-3-gallate on the protein composition of the acquired enamel pellicle. 2017 Arch. Oral Biol. pmid:28622550
Rehage M et al. Oral astringent stimuli alter the enamel pellicle's ultrastructure as revealed by electron microscopy. 2017 J Dent pmid:28619693
Miyauchi S et al. Quality evaluation of green tea leaf cultured under artificial light condition using gas chromatography/mass spectrometry. 2017 J. Biosci. Bioeng. pmid:27568369
Shanmuganathan S et al. Epigallocatechin gallate & curcumin prevent transforming growth factor beta 1-induced epithelial to mesenchymal transition in ARPE-19 cells. 2017 Indian J. Med. Res. pmid:29578200
Zhu W et al. A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. 2017 J. Nutr. Biochem. pmid:28772148
Malongane F et al. The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review. 2017 J. Sci. Food Agric. pmid:28585285
Linne B and Simons CT Quantification of Oral Roughness Perception and Comparison with Mechanism of Astringency Perception. 2017 Chem. Senses pmid:28575283
Meena KP et al. Catechin-loaded Eudragit microparticles for the management of diabetes: formulation, characterization and in vivo evaluation of antidiabetic efficacy. 2017 J Microencapsul pmid:28562190
He Y et al. Epigallocatechin-3-gallate attenuates cerebral cortex damage and promotes brain regeneration in acrylamide-treated rats. 2017 Food Funct pmid:28561817
Kim AR et al. Catechins activate muscle stem cells by Myf5 induction and stimulate muscle regeneration. 2017 Biochem. Biophys. Res. Commun. pmid:28546002
Seo DJ and Choi C Inhibitory mechanism of five natural flavonoids against murine norovirus. 2017 Phytomedicine pmid:28545670
Wang J et al. Physicochemical characterization of the oolong tea polysaccharides with high molecular weight and their synergistic effects in combination with polyphenols on hepatocellular carcinoma. 2017 Biomed. Pharmacother. pmid:28355590
Chen J et al. Anti-skin-aging effect of epigallocatechin gallate by regulating epidermal growth factor receptor pathway on aging mouse model induced by d-Galactose. 2017 Mech. Ageing Dev. pmid:28343910
Sharma R et al. Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice. 2017 Biogerontology pmid:28341876
Wang L et al. Monitoring the Consistency Quality and Antioxidant Activity of Da Hong Pao Teas by HPLC Fingerprinting. 2017 J Chromatogr Sci pmid:28334752
Gee JR et al. A Phase II Randomized, Double-blind, Presurgical Trial of Polyphenon E in Bladder Cancer Patients to Evaluate Pharmacodynamics and Bladder Tissue Biomarkers. 2017 Cancer Prev Res (Phila) pmid:28325826
Atala A Re: Mg(II)-Catechin Nanoparticles Delivering siRNA Targeting EIF5A2 Inhibit Bladder Cancer Cell Growth In Vitro and In Vivo. 2017 J. Urol. pmid:29370654
He Y et al. Effect of epigallocatechin-3-gallate on acrylamide-induced oxidative stress and apoptosis in PC12 cells. 2017 Hum Exp Toxicol pmid:27920337
Lan X et al. (-)-Epicatechin, a Natural Flavonoid Compound, Protects Astrocytes Against Hemoglobin Toxicity via Nrf2 and AP-1 Signaling Pathways. 2017 Mol. Neurobiol. pmid:27864733
Redan BW et al. Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts. 2017 Food Funct pmid:27808339
Yuan L et al. Competitive binding of (-)-epigallocatechin-3-gallate and 5-fluorouracil to human serum albumin: A fluorescence and circular dichroism study. 2017 Spectrochim Acta A Mol Biomol Spectrosc pmid:27776313
Novakovic A et al. Endothelium-dependent vasorelaxant effect of procyanidin B2 on human internal mammary artery. 2017 Eur. J. Pharmacol. pmid:28414054
Lin X et al. Spontaneously Assembled Nano-aggregates in Clear Green Tea Infusions from Camellia ptilophylla and Camellia sinensis. 2017 J. Agric. Food Chem. pmid:28412808
Wu M et al. Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28408365
Sun L et al. Simultaneous separation and purification of chlorogenic acid, epicatechin, hyperoside and phlorizin from thinned young Qinguan apples by successive use of polyethylene and polyamide resins. 2017 Food Chem pmid:28407923
Lee SJ et al. Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts. 2017 PLoS ONE pmid:28384253
Kadhum WR et al. A Novel Chemical Enhancer Approach for Transdermal Drug Delivery with C-Monoglycerol Ester Liquid Crystal-forming Lipid. 2017 J Oleo Sci pmid:28381773
Karthikeyan B et al. Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration. 2017 Apoptosis pmid:27778132
Dostal AM et al. Green tea extract and catechol-O-methyltransferase genotype modify the post-prandial serum insulin response in a randomised trial of overweight and obese post-menopausal women. 2017 J Hum Nutr Diet pmid:27600055
Chang HH et al. Catechins Blunt the Effects of oxLDL and its Primary Metabolite Phosphatidylcholine Hydroperoxide on Endothelial Dysfunction Through Inhibition of Oxidative Stress and Restoration of eNOS in Rats. 2017 Kidney Blood Press. Res. pmid:29161690
Li X et al. Attenuated mTOR Signaling and Enhanced Glucose Homeostasis by Dietary Supplementation with Lotus Seedpod Oligomeric Procyanidins in Streptozotocin (STZ)-Induced Diabetic Mice. 2017 J. Agric. Food Chem. pmid:28314100
Ho GT et al. Phenolic Elderberry Extracts, Anthocyanins, Procyanidins, and Metabolites Influence Glucose and Fatty Acid Uptake in Human Skeletal Muscle Cells. 2017 J. Agric. Food Chem. pmid:28303711
de Oliveira Caleare A et al. Flavan-3-ols and proanthocyanidins from Limonium brasiliense inhibit the adhesion of Porphyromonas gingivalis to epithelial host cells by interaction with gingipains. 2017 Fitoterapia pmid:28288871
Luo XL et al. A new catechin derivative from the fruits of Rosa sterilis S. D. Shi. 2017 Nat. Prod. Res. pmid:28287271
Takahashi H et al. Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. 2017 Exp. Gerontol. pmid:28286171
Đorđević NO et al. Comparative analytical study of the selected wine varieties grown in Montenegro. 2017 Nat. Prod. Res. pmid:28278676
Zinellu A et al. N- and S-homocysteinylation reduce the binding of human serum albumin to catechins. 2017 Eur J Nutr pmid:26658763
Peter B et al. Green tea polyphenol tailors cell adhesivity of RGD displaying surfaces: multicomponent models monitored optically. 2017 Sci Rep pmid:28186133
Xie J et al. A novel ECG analog 4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and ROS. 2017 Sci Rep pmid:28186123
Sanna V et al. Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy. 2017 Sci Rep pmid:28145499
Hora M et al. Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains. 2017 Sci Rep pmid:28128355
Lee S et al. Antibacterial activity of epigallocatechin-3-gallate (EGCG) and its synergism with β-lactam antibiotics sensitizing carbapenem-associated multidrug resistant clinical isolates of Acinetobacter baumannii. 2017 Phytomedicine pmid:28160861
Sun L et al. Effects of thinned young apple polyphenols on the quality of grass carp (Ctenopharyngodon idellus) surimi during cold storage. 2017 Food Chem pmid:28159283
Yang R et al. Urea-Driven Epigallocatechin Gallate (EGCG) Permeation into the Ferritin Cage, an Innovative Method for Fabrication of Protein-Polyphenol Co-assemblies. 2017 J. Agric. Food Chem. pmid:28158944
Avadhani KS et al. Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage. 2017 Drug Deliv pmid:28155509
Kumazoe M et al. Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216. 2017 J. Biol. Chem. pmid:28154178
Dias TR et al. Implications of epigallocatechin-3-gallate in cultured human Sertoli cells glycolytic and oxidative profile. 2017 Toxicol In Vitro pmid:28323106
Mizuno M et al. Synthesis and antioxidant activity of a procyanidin B3 analogue. 2017 Bioorg. Med. Chem. Lett. pmid:28082039
Li W et al. Self-assembly of green tea catechin derivatives in nanoparticles for oral lycopene delivery. 2017 J Control Release pmid:28077264
Cui L et al. Extraction of Epigallocatechin Gallate and Epicatechin Gallate from Tea Leaves Using β-Cyclodextrin. 2017 J. Food Sci. pmid:28071811
Dag D and Oztop MH Formation and Characterization of Green Tea Extract Loaded Liposomes. 2017 J. Food Sci. pmid:28071801
Zhang L et al. Effect of metal ions on the binding reaction of (-)-epigallocatechin gallate to β-lactoglobulin. 2017 Food Chem pmid:27979181
Liu Y et al. A novel electrochemical sensor based on a molecularly imprinted polymer for the determination of epigallocatechin gallate. 2017 Food Chem pmid:27979069
Ahmed B et al. Antiadipogenic Effects and Mechanisms of Combinations of Genistein, Epigallocatechin-3-Gallate, and/or Resveratrol in Preadipocytes. 2017 J Med Food pmid:27976976
Yao YF et al. (-)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice. 2017 Life Sci. pmid:27956351
Dong Z et al. (-)-Epicatechin rescues the As O -induced HERG K channel deficiency possibly through upregulating transcription factor SP1 expression. 2017 J. Biochem. Mol. Toxicol. pmid:28768059
Chen Y et al. Differential expression of microRNAs contributed to the health efficacy of EGCG in in vitro subarachnoid hemorrhage model. 2017 Food Funct pmid:29160895