(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Authors Title Published Journal PubMed Link
Kerry N and Rice-Evans C Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships. 1999 J. Neurochem. pmid:10386977
Saeki K et al. Apoptosis-inducing activity of polyphenol compounds derived from tea catechins in human histiolytic lymphoma U937 cells. 1999 Biosci. Biotechnol. Biochem. pmid:10227148
Sato D Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea. 1999 Int. J. Urol. pmid:10226814
de Mejía EG et al. Antimutagenic effects of natural phenolic compounds in beans. 1999 Mutat. Res. pmid:10224317
Huang Y et al. Involvement of endothelium/nitric oxide in vasorelaxation induced by purified green tea (-)epicatechin. 1999 Biochim. Biophys. Acta pmid:10216249
Yoshioka N et al. Effect of polyphenon-60 on the development of renal cell tumors in rats treated with N-ethyl-N hydroxyethylnitrosamine. 1999 Cancer Lett. pmid:10211943
Kim SU et al. Inhibition of chitin synthase II by catechins from stem bark of Taxus cuspidata. 1999 Planta Med. pmid:10083852
Guo Q et al. ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers. 1999 Biochim. Biophys. Acta pmid:10082983
Okushio K et al. Identification of (-)-epicatechin metabolites and their metabolic fate in the rat. 1999 Drug Metab. Dispos. pmid:9929521
Kondo K et al. Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action. 1999 Free Radic. Biol. Med. pmid:10515590
Facino RM et al. Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats. 1999 Life Sci. pmid:10069526
Zigman S et al. Effects of green tea polyphenols on lens photooxidative stress. 1999 Biol. Bull. pmid:10573853
Yasokawa M et al. (-)-Epigallocatechin gallate inhibits mos activation-mediated xenopus oocyte maturation induced by progesterone. 1999 FEBS Lett. pmid:10606745
Chan PT et al. Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet. 1999 J. Nutr. pmid:10356071
Jacobsen C et al. Partitioning of selected antioxidants in mayonnaise. 1999 J. Agric. Food Chem. pmid:10552692
Nanjo F et al. Radical scavenging activity of tea catechins and their related compounds. 1999 Biosci. Biotechnol. Biochem. pmid:10610125
Maeda-Yamamoto M et al. Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells. 1999 J. Agric. Food Chem. pmid:10794635
Kondo K et al. Mechanistic studies of catechins as antioxidants against radical oxidation. 1999 Arch. Biochem. Biophys. pmid:9917331
Guo Q et al. Electron spin resonance study of free radicals formed from a procyanidin-rich pine (Pinus maritima) bark extract, pycnogenol. 1999 Free Radic. Biol. Med. pmid:10641725
Tsuchiya H Effects of green tea catechins on membrane fluidity. 1999 Pharmacology pmid:10352424
Safety assessment and potential health benefits of food components based on selected scientific criteria. ILSI North America Technical Committee on Food Components for Health Promotion. 1999 Crit Rev Food Sci Nutr pmid:10367185
Yang CS et al. Human salivary tea catechin levels and catechin esterase activities: implication in human cancer prevention studies. 1999 Cancer Epidemiol. Biomarkers Prev. pmid:9950244
Li XC et al. Antifungal activity of (-)-epigallocatechin gallate from Coccoloba dugandiana. 1999 Planta Med. pmid:10630130
Frémont L et al. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. 1999 Life Sci. pmid:10403511
Hoshino N et al. Damage to the cytoplasmic membrane of Escherichia coli by catechin-copper (II) complexes. 1999 Free Radic. Biol. Med. pmid:10641717
Bors W and Michel C Antioxidant capacity of flavanols and gallate esters: pulse radiolysis studies. 1999 Free Radic. Biol. Med. pmid:10641736
Brown MD Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer. 1999 Altern Med Rev pmid:10559550
Hayakawa F et al. DNA cleavage activities of (-)-epigallocatechin, (-)-epicatechin, (+)-catechin, and (-)-epigallocatechin gallate with various kinds of metal ions. 1999 Biosci. Biotechnol. Biochem. pmid:10610127
Sugita-Konishi Y et al. Epigallocatechin gallate and gallocatechin gallate in green tea catechins inhibit extracellular release of Vero toxin from enterohemorrhagic Escherichia coli O157:H7. 1999 Biochim. Biophys. Acta pmid:10572924
Yanagida A et al. Fractionation of apple procyanidins by size-exclusion chromatography. 1999 J Chromatogr A pmid:10514983
Lin YL et al. Theaflavin-3,3'-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kappaB in macrophages. 1999 Eur. J. Pharmacol. pmid:10079014
Min KR et al. (-)-Epiafzelechin: cyclooxygenase-1 inhibitor and anti-inflammatory agent from aerial parts of Celastrus orbiculatus. 1999 Planta Med. pmid:10418338
Suganuma M et al. Synergistic effects of (--)-epigallocatechin gallate with (--)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9. 1999 Cancer Res. pmid:9892181
Xu M and Dashwood RH Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis. 1999 Cancer Lett. pmid:10503900
Rimbach G et al. Effect of procyanidins from Pinus maritima on glutathione levels in endothelial cells challenged by 3-morpholinosydnonimine or activated macrophages. 1999 Redox Rep. pmid:10658822
Lotito SB and Fraga CG (+)-Catechin as antioxidant: mechanisms preventing human plasma oxidation and activity in red wines. 1999 Biofactors pmid:10609873
Manach C et al. Comparison of the bioavailability of quercetin and catechin in rats. 1999 Free Radic. Biol. Med. pmid:10641719
Es-Safi NE et al. New polyphenolic compounds with xanthylium skeletons formed through reaction between (+)-catechin and glyoxylic acid. 1999 J. Agric. Food Chem. pmid:10606598
Schulz H et al. Application of near-infrared reflectance spectroscopy to the simultaneous prediction of alkaloids and phenolic substances in green tea leaves. 1999 J. Agric. Food Chem. pmid:10606573
Subramanian N et al. Role of polyphenol oxidase and peroxidase in the generation of black tea theaflavins. 1999 J. Agric. Food Chem. pmid:10552528
Es-Safi NE et al. Studies on the acetaldehyde-induced condensation of (-)-epicatechin and malvidin 3-O-glucoside in a model solution system. 1999 J. Agric. Food Chem. pmid:10552502
Dvorakova K et al. Pharmacokinetics of the green tea derivative, EGCG, by the topical route of administration in mouse and human skin. 1999 Cancer Chemother. Pharmacol. pmid:10071985
Chen W et al. Inhibition of ultraviolet B--induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line. 1999 Mol. Carcinog. pmid:10078934
Katiyar SK et al. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. 1999 Photochem. Photobiol. pmid:10048310
Dulloo AG et al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. 1999 Am. J. Clin. Nutr. pmid:10584049
Arteel GE and Sies H Protection against peroxynitrite by cocoa polyphenol oligomers. 1999 FEBS Lett. pmid:10580113
Surh Y Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. 1999 Mutat. Res. pmid:10518003
Lazarus SA et al. Chocolate contains additional flavonoids not found in tea. 1999 Lancet pmid:10577676
Suganuma M et al. Green tea and cancer chemoprevention. 1999 Mutat. Res. pmid:10518005
Yoshida H et al. Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein. 1999 Biochem. Pharmacol. pmid:10571243
L'Allemain G [Multiple actions of EGCG, the main component of green tea]. 1999 Bull Cancer pmid:10519963
Chen YC et al. Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theaflavin-3,3'-digallate from black tea in NIH3T3 cells. 1999 J. Agric. Food Chem. pmid:10563991
Dufour C and Bayonove CL Interactions between wine polyphenols and aroma substances. An insight at the molecular level. 1999 J. Agric. Food Chem. pmid:10563952
Hammerstone JF et al. Identification of procyanidins in cocoa (Theobroma cacao) and chocolate using high-performance liquid chromatography/mass spectrometry. 1999 J. Agric. Food Chem. pmid:10563922
Saint-Cricq De Gaulejac N et al. Comparative study of polyphenol scavenging activities assessed by different methods. 1999 J. Agric. Food Chem. pmid:10563911
Holodniy M et al. A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. 1999 Am. J. Gastroenterol. pmid:10566728
Garbisa S et al. Tumor invasion: molecular shears blunted by green tea. 1999 Nat. Med. pmid:10545959
Bhisey RA et al. Long-term carcinogenicity of pan masala in Swiss mice. 1999 Int. J. Cancer pmid:10521807
Devic M et al. The BANYULS gene encodes a DFR-like protein and is a marker of early seed coat development. 1999 Plant J. pmid:10504561
Noguchi Y et al. Inhibition of Df-protease associated with allergic diseases by polyphenol. 1999 J. Agric. Food Chem. pmid:10552595
Zhang HY et al. Theoretical elucidation of activity differences of five phenolic antioxidants. 1999 Zhongguo Yao Li Xue Bao pmid:10452126
Nagata H et al. Antioxidative action of flavonoids, quercetin and catechin, mediated by the activation of glutathione peroxidase. 1999 Tokai J. Exp. Clin. Med. pmid:10530620
Donovan JL et al. Catechin is present as metabolites in human plasma after consumption of red wine. 1999 J. Nutr. pmid:10460201
Takahashi T et al. Toxicological studies on procyanidin B-2 for external application as a hair growing agent. 1999 Food Chem. Toxicol. pmid:10456683
Shoji T et al. Gel permeation chromatography of anthocyanin pigments from Rosé cider and red wine. 1999 J. Agric. Food Chem. pmid:10552581
Menon LG et al. Anti-metastatic activity of curcumin and catechin. 1999 Cancer Lett. pmid:10454257
Harada M et al. Identification of the major antioxidative metabolites in biological fluids of the rat with ingested (+)-catechin and (-)-epicatechin. 1999 Biosci. Biotechnol. Biochem. pmid:10427682
Isemura M et al. Inhibition of matrix metalloproteinases by tea catechins and related polyphenols. 1999 Ann. N. Y. Acad. Sci. pmid:10415792
Zhong Z et al. Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers. 1999 J. Pharmacol. Exp. Ther. pmid:10411569
Mabe K et al. In vitro and in vivo activities of tea catechins against Helicobacter pylori. 1999 Antimicrob. Agents Chemother. pmid:10390246
Swiercz R et al. Angiostatic activity of synthetic inhibitors of urokinase type plasminogen activator. 1999 May-Jun Oncol. Rep. pmid:10203585
Shankel DM et al. Role of antimutagens/anticarcinogens in cancer prevention. 2000 Biofactors pmid:11216471
Dong Z Effects of food factors on signal transduction pathways. 2000 Biofactors pmid:11216482
de Pascual-Teresa S et al. Quantitative analysis of flavan-3-ols in Spanish foodstuffs and beverages. 2000 J. Agric. Food Chem. pmid:11087482
Ma C et al. Inhibitory effects on HIV-1 protease of constituents from the wood of Xanthoceras sorbifolia. 2000 J. Nat. Prod. pmid:10691716
Yang L et al. Oxidative stability of conjugated linoleic acid isomers. 2000 J. Agric. Food Chem. pmid:10956070
Kao YH et al. Modulation of obesity by a green tea catechin. 2000 Am. J. Clin. Nutr. pmid:11063454
Williams SN et al. Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. 2000 Chem. Biol. Interact. pmid:11064004
Mukhtar H and Ahmad N Tea polyphenols: prevention of cancer and optimizing health. 2000 Am. J. Clin. Nutr. pmid:10837321
Ahmad N et al. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate. 2000 Biochem. Biophys. Res. Commun. pmid:10964666
Nomura M et al. Inhibition of ultraviolet B-induced AP-1 activation by theaflavins from black tea. 2000 Mol. Carcinog. pmid:10942531
Shi X et al. Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr(VI)-induced DNA damage and Cr(IV)- or TPA-stimulated NF-kappaB activation. 2000 Mol. Cell. Biochem. pmid:10839202
Hashimoto R et al. Inhibition of radical reaction of apolipoprotein B-100 and alpha-tocopherol in human plasma by green tea catechins. 2000 J. Agric. Food Chem. pmid:11312811
Lee S et al. Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils. 2000 Neurosci. Lett. pmid:10863027
Kao YH et al. Modulation of endocrine systems and food intake by green tea epigallocatechin gallate. 2000 Endocrinology pmid:10698173
Erickson AJ et al. Nitrification inhibitors from the roots of Leucaena leucocephala. 2000 J. Agric. Food Chem. pmid:11312789
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Reguant C et al. Influence of phenolic compounds on the physiology of Oenococcus oeni from wine. 2000 J. Appl. Microbiol. pmid:10849183
Buschmann H et al. Hydrogen peroxide and flavan-3-ols in storage roots of cassava (Manihot esculenta crantz) during postharvest deterioration. 2000 J. Agric. Food Chem. pmid:11087513
Kobayashi Y et al. Green tea polyphenols inhibit the sodium-dependent glucose transporter of intestinal epithelial cells by a competitive mechanism. 2000 J. Agric. Food Chem. pmid:11087528
Mao TK et al. The effect of cocoa procyanidins on the transcription and secretion of interleukin 1 beta in peripheral blood mononuclear cells. 2000 Life Sci. pmid:11210713
Degenhardt A et al. Isolation of black tea pigments using high-speed countercurrent chromatography and studies on properties of black tea polymers. 2000 J. Agric. Food Chem. pmid:11087459
Higashimoto M et al. Inhibitory effects of tea extracts on the mutagenicity of 1-methyl-1, 2,3,4-tetrahydro-beta-carboline-3-carboxylic acid on treatment with nitrite in the presence of ethanol. 2000 Food Chem. Toxicol. pmid:10685009
Kuruto-Niwa R et al. Effects of tea catechins on the ERE-regulated estrogenic activity. 2000 J. Agric. Food Chem. pmid:11312808
Komatsu M and Hiramatsu M The efficacy of an antioxidant cocktail on lipid peroxide level and superoxide dismutase activity in aged rat brain and DNA damage in iron-induced epileptogenic foci. 2000 Toxicology pmid:10962133
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Saeki K et al. Importance of a pyrogallol-type structure in catechin compounds for apoptosis-inducing activity. 2000 Phytochemistry pmid:10703063
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