(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Zhao L et al. A new molecular mechanism underlying the EGCG-mediated autophagic modulation of AFP in HepG2 cells. 2017 Cell Death Dis pmid:29095434
Arruda MO et al. The Hydroalcoholic Extract Obtained from L. Leaves Attenuates Oxidative Stress and Improves Survival in Lipopolysaccharide-Treated Macrophages. 2017 J Immunol Res pmid:29085843
Saarenhovi M et al. The effect of an apple polyphenol extract rich in epicatechin and flavan-3-ol oligomers on brachial artery flow-mediated vasodilatory function in volunteers with elevated blood pressure. 2017 Nutr J pmid:29078780
Fong-Ngern K et al. Microvillar injury in renal tubular epithelial cells induced by calcium oxalate crystal and the protective role of epigallocatechin-3-gallate. 2017 FASEB J. pmid:27825102
Meshitsuka S et al. Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis. 2017 Int. J. Hematol. pmid:27815860
Shirai N The Inhibitory Effects of Anthocyanin-Rich Sunrouge Tea on Pancreatic Lipase Activity. 2017 J Oleo Sci pmid:29129901
Yu KY et al. Qualitative and quantitative analysis of chemical constituents in Ardisiae Japonicae Herba. 2017 J Sep Sci pmid:28926203
Rothwell JA et al. Polyphenols: dietary assessment and role in the prevention of cancers. 2017 Curr Opin Clin Nutr Metab Care pmid:28915128
Samavat H et al. A Randomized Controlled Trial of Green Tea Extract Supplementation and Mammographic Density in Postmenopausal Women at Increased Risk of Breast Cancer. 2017 Cancer Prev Res (Phila) pmid:28904061
Cyboran-Mikołajczyk S et al. Interaction of procyanidin B with membrane lipids - Fluorescence, DSC and FTIR studies. 2017 Biochim. Biophys. Acta pmid:28472615
Xiang C et al. Epigallocatechin‑3‑gallate protects from high glucose induced podocyte apoptosis via suppressing endoplasmic reticulum stress. 2017 Mol Med Rep pmid:28901409
Machova Urdzikova L et al. A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines. 2017 Neuropharmacology pmid:28899730
Fujiki H et al. Human cancer stem cells are a target for cancer prevention using (-)-epigallocatechin gallate. 2017 J. Cancer Res. Clin. Oncol. pmid:28942499
Zhou X et al. Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells through the Activation of Nrf2/Caspase-3 Signaling. 2017 J. Vasc. Res. pmid:28942440
Pyner A et al. Inhibition of Human and Rat Sucrase and Maltase Activities To Assess Antiglycemic Potential: Optimization of the Assay Using Acarbose and Polyphenols. 2017 J. Agric. Food Chem. pmid:28914528
Dhanani T et al. Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca. 2017 J Food Drug Anal pmid:28911654
Wang L et al. An analysis method for flavan-3-ols using high performance liquid chromatography coupled with a fluorescence detector. 2017 J Food Drug Anal pmid:28911633
Cejnar R et al. Development of engineered yeast for biosorption of beer haze-active polyphenols. 2017 Appl. Microbiol. Biotechnol. pmid:27770176
Hu B et al. Food macromolecule based nanodelivery systems for enhancing the bioavailability of polyphenols. 2017 J Food Drug Anal pmid:28911541
Sharma N et al. Epigallocatechin gallate, an active green tea compound inhibits the Zika virus entry into host cells via binding the envelope protein. 2017 Int. J. Biol. Macromol. pmid:28666829
Novak Jovanović I and Miličević A A new, simplified model for the estimation of polyphenol oxidation potentials based on the number of OH groups. 2017 Arh Hig Rada Toksikol pmid:28665801
Kim SN et al. Effects of Epigallocatechin-3-Gallate on Autophagic Lipolysis in Adipocytes. 2017 Nutrients pmid:28665330
Nakasone N et al. Epigallocatechin gallate inhibits the type III secretion system of Gram-negative enteropathogenic bacteria under model conditions. 2017 FEMS Microbiol. Lett. pmid:28651361
Hsieh YP et al. Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts. 2017 J. Formos. Med. Assoc. pmid:26922429
Wang Z et al. Epigallocatechin-3-gallate inhibit replication of white spot syndrome virus in Scylla paramamosain. 2017 Fish Shellfish Immunol. pmid:28648884
Sieniawska E et al. LC-QTOF-MS Analysis and Activity Profiles of Popular Antioxidant Dietary Supplements in Terms of Quality Control. 2017 Oxid Med Cell Longev pmid:28642814
Cheng H et al. (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. 2017 Mol Nutr Food Res pmid:28734036
Matić P et al. Validation of Spectrophotometric Methods for the Determination of Total Polyphenol and Total Flavonoid Content. 2017 J AOAC Int pmid:28730980
Koch W et al. Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time. 2017 J AOAC Int pmid:28707612
Borse V et al. Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity. 2017 Cell Death Dis pmid:28703809
Bitto A et al. Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice. 2017 Inflamm. Res. pmid:28238167
Pan C et al. NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage. 2017 Oxid Med Cell Longev pmid:28698767
Xiong LG et al. Tea polyphenol epigallocatechin gallate inhibits Escherichia coli by increasing endogenous oxidative stress. 2017 Food Chem pmid:27664626
Abd El-Rahman SS et al. Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats. 2017 Am. J. Med. Sci. pmid:28755734
Kasai N et al. Effect of epigallocatechin-3-o-gallate and quercetin on the cryopreservation of cartilage tissue. 2017 Biosci. Biotechnol. Biochem. pmid:27648863
Chen Y et al. Anti-myocardial Ischemia Effect and Components of Litchi Pericarp Extracts. 2017 Phytother Res pmid:28744920
Kato E et al. Astilbe thunbergii reduces postprandial hyperglycemia in a type 2 diabetes rat model via pancreatic alpha-amylase inhibition by highly condensed procyanidins. 2017 Biosci. Biotechnol. Biochem. pmid:28743229
Mi Y et al. EGCG ameliorates high-fat- and high-fructose-induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS. 2017 FASEB J. pmid:28739640
Gao X et al. Cellular antioxidant, methylglyoxal trapping, and anti-inflammatory activities of cocoa tea (Camellia ptilophylla Chang). 2017 Food Funct pmid:28725904
Ke Z et al. Discovery of a potent angiotensin converting enzyme inhibitor via virtual screening. 2017 Bioorg. Med. Chem. Lett. pmid:28712707
Qi S et al. Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina. 2017 Mol. Vis. pmid:28458506
Srinivasan E and Rajasekaran R Probing the inhibitory activity of epigallocatechin-gallate on toxic aggregates of mutant (L84F) SOD1 protein through geometry based sampling and steered molecular dynamics. 2017 J. Mol. Graph. Model. pmid:28458007
Sun W et al. Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1. 2017 Free Radic. Biol. Med. pmid:28457936
Mülek M et al. Distribution of Constituents and Metabolites of Maritime Pine Bark Extract (Pycnogenol) into Serum, Blood Cells, and Synovial Fluid of Patients with Severe Osteoarthritis: A Randomized Controlled Trial. 2017 Nutrients pmid:28452960
Zhang L et al. Procyanidin, a kind of biological flavonoid, induces protective anti-tumor immunity and protects mice from lethal B16F10 challenge. 2017 Int. Immunopharmacol. pmid:28445856
Shirakami Y et al. Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation. 2017 Int J Mol Sci pmid:28445390
Deiana M et al. Derangement of intestinal epithelial cell monolayer by dietary cholesterol oxidation products. 2017 Free Radic. Biol. Med. pmid:29102636
Xinqiang S et al. Bioinformatics Analysis on Molecular Mechanism of Green Tea Compound Epigallocatechin-3-Gallate Against Ovarian Cancer. 2017 Clin Transl Sci pmid:28504421
Oliver S et al. Tuneable catechin functionalisation of carbohydrate polymers. 2017 Carbohydr Polym pmid:28504171
Zhang M and Xu M Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9. 2017 Fundam Clin Pharmacol pmid:28477356
Divya P et al. Epigallocatechin gallate protects BEAS-2B cells from lipopolysaccharide-induced apoptosis through upregulation of gastrin-releasing peptide. 2017 Mol. Cell. Biochem. pmid:28432554
Zhang QA et al. Effect of ultrasound on the interaction between (-)-epicatechin gallate and bovine serum albumin in a model wine. 2017 Ultrason Sonochem pmid:28427650
Lee PMY et al. Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men. 2017 Prostate Cancer Prostatic Dis. pmid:28417981
Robinson AL et al. Polyvinylpolypyrrolidone reduces cross-reactions between antibodies and phenolic compounds in an enzyme-linked immunosorbent assay for the detection of ochratoxin A. 2017 Food Chem pmid:27507446
Yates AA et al. Bioactive nutrients - Time for tolerable upper intake levels to address safety. 2017 Regul. Toxicol. Pharmacol. pmid:28110066
Guo J et al. Multivariate statistical analysis of the polyphenolic constituents in kiwifruit juices to trace fruit varieties and geographical origins. 2017 Food Chem pmid:28490110
Ye F et al. Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains. 2017 J. Biol. Chem. pmid:28487468
Sato K et al. Effect of epigallocatechin-3-gallate on the increase in type II collagen accumulation in cartilage-like MSC sheets. 2017 Biosci. Biotechnol. Biochem. pmid:28485205
Fouad AA et al. Epigallocatechin-3-gallate counters cisplatin toxicity of rat testes. 2017 Pharm Biol pmid:28478745
Hsiao HB et al. (-)-Epicatechin 3-O-β-D-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways. 2017 BMC Complement Altern Med pmid:28468652
Pence BD et al. Dose-dependent decrease in mortality with no cognitive or muscle function improvements due to dietary EGCG supplementation in aged mice. 2017 Appl Physiol Nutr Metab pmid:28177724
Moon JY et al. α-Syntrophin stabilizes catalase to reduce endogenous reactive oxygen species levels during myoblast differentiation. 2017 FEBS J. pmid:28485891
Kwon YS et al. Effects of Epigallocatechin Gallate, an Antibacterial Cross-linking Agent, on Proliferation and Differentiation of Human Dental Pulp Cells Cultured in Collagen Scaffolds. 2017 J Endod pmid:28132713
Shetty PK et al. Skin Delivery of EGCG and Silibinin: Potential of Peptide Dendrimers for Enhanced Skin Permeation and Deposition. 2017 AAPS PharmSciTech pmid:28124212
Oya Y et al. Down-regulation of histone deacetylase 4, -5 and -6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin. 2017 J. Nutr. Biochem. pmid:28103535
Zhao Y et al. Synergistic effects of caffeine and catechins on lipid metabolism in chronically fed mice via the AMP-activated protein kinase signaling pathway. 2017 Eur J Nutr pmid:27444711
Roomi MW et al. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells. 2017 Oncol. Rep. pmid:28112361
Chen JH et al. Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells. 2017 Eur J Nutr pmid:27318926
Luo H et al. Characterization of Active Anthocyanin Degradation in the Petals of Rosa chinensis and Brunfelsia calycina Reveals the Effect of Gallated Catechins on Pigment Maintenance. 2017 Int J Mol Sci pmid:28346355
Saito A Challenges and complexity of functionality evaluation of flavan-3-ol derivatives. 2017 Biosci. Biotechnol. Biochem. pmid:28345490
Li Q et al. Affinity chromatographic methodologies based on immobilized voltage dependent anion channel isoform 1 and application in protein-ligand interaction analysis and bioactive compounds screening from traditional medicine. 2017 J Chromatogr A pmid:28342583
Hollands WJ et al. Development, validation and evaluation of an analytical method for the determination of monomeric and oligomeric procyanidins in apple extracts. 2017 J Chromatogr A pmid:28341432
Mangels DR and Mohler ER Catechins as Potential Mediators of Cardiovascular Health. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:28336557
Fan FY et al. Catechins and Their Therapeutic Benefits to Inflammatory Bowel Disease. 2017 Molecules pmid:28335502
Cordero-Herrera I et al. (-)-Epicatechin attenuates high-glucose-induced inflammation by epigenetic modulation in human monocytes. 2017 Eur J Nutr pmid:26704714
Xu J et al. A Review of the Antiviral Role of Green Tea Catechins. 2017 Molecules pmid:28805687
Yu J et al. Development of Epigallocatechin-3-gallate-Encapsulated Nanohydroxyapatite/Mesoporous Silica for Therapeutic Management of Dentin Surface. 2017 ACS Appl Mater Interfaces pmid:28703572
Wang X et al. Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice. 2017 World J. Gastroenterol. pmid:29290650
Gautam S et al. Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative. 2017 Biochim. Biophys. Acta pmid:28238838
Dudek MK et al. Trimeric and Tetrameric A-Type Procyanidins from Peanut Skins. 2017 J. Nat. Prod. pmid:28231711
Sun P et al. Combined small RNA and degradome sequencing reveals complex microRNA regulation of catechin biosynthesis in tea (Camellia sinensis). 2017 PLoS ONE pmid:28225779
Ikeda M et al. Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin. 2017 Molecules pmid:28218710
Bello M et al. Molecular recognition between pancreatic lipase and natural and synthetic inhibitors. 2017 Int. J. Biol. Macromol. pmid:28212930
Chang JH et al. Epigallocatechin-3-gallate modulates arrhythmogenic activity and calcium homeostasis of left atrium. 2017 Int. J. Cardiol. pmid:28117139
Chang CY et al. Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization. 2017 Int J Nanomedicine pmid:28115846
Ikarashi N et al. Epigallocatechin gallate induces a hepatospecific decrease in the CYP3A expression level by altering intestinal flora. 2017 Eur J Pharm Sci pmid:28115221
Zhang QA et al. Antioxidant Evaluation and Composition Analysis of Extracts from Fuzhuan Brick Tea and Its Comparison with Two Instant Tea Products. 2017 J AOAC Int pmid:28109088
Tiwari M et al. EGCG, a tea polyphenol, as a potential mitigator of hematopoietic radiation injury in mice. 2017 Biomed. Pharmacother. pmid:28107697
Yu HH et al. Effects of Epigallocatechin-3-gallate (EGCG) on the bond strength of fiber posts to Sodium hypochlorite (NaOCl) treated intraradicular dentin. 2017 Sci Rep pmid:28652570
Lorenz M et al. Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG). 2017 Sci Rep pmid:28536463
Bai Q et al. Epigallocatechin-3-gallate promotes angiogenesis via up-regulation of Nfr2 signaling pathway in a mouse model of ischemic stroke. 2017 Behav. Brain Res. pmid:28042007
Sampath C et al. Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity. 2017 Biomed. Pharmacother. pmid:28040599
Luo KW et al. EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9. 2017 J. Nutr. Biochem. pmid:28040581
Prince PD et al. LPS-induced renal inflammation is prevented by (-)-epicatechin in rats. 2017 Redox Biol pmid:28039839
An TT et al. Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form. 2017 Redox Biol pmid:28038426
Mariotti-Celis MS et al. The Antioxidant and Safety Properties of Spent Coffee Ground Extracts Impacted by the Combined Hot Pressurized Liquid Extraction-Resin Purification Process. 2017 Molecules pmid:29271942
Ganesh HVS et al. Epigallocatechin Gallate-Modified Graphite Paste Electrode for Simultaneous Detection of Redox-Active Biomolecules. 2017 Sensors (Basel) pmid:29271930
Yu C et al. Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway. 2017 Int. J. Biol. Sci. pmid:29230104
Haney CM et al. Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules. 2017 Biochemistry pmid:28045494
Harati K et al. Anti‑proliferative activity of epigallocatechin‑3‑gallate and silibinin on soft tissue sarcoma cells. 2017 Mol Med Rep pmid:27909727