(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Jin UH et al. Inhibitory effect of Salvia miltiorrhia BGE on matrix metalloproteinase-9 activity and migration of TNF-alpha-induced human aortic smooth muscle cells. 2006 Vascul. Pharmacol. pmid:16540379
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Kim Y and Chang KO Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses. 2018 Virus Res. pmid:29382552
Zhao C et al. In vitro evaluation of the antiviral activity of the synthetic epigallocatechin gallate analog-epigallocatechin gallate (EGCG) palmitate against porcine reproductive and respiratory syndrome virus. 2014 Viruses pmid:24566281
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Wang YZ et al. (-)-Epigallocatechin-3-gallate enhances poly I:C-induced interferon-λ1 production and inhibits hepatitis C virus replication in hepatocytes. 2017 World J. Gastroenterol. pmid:28932081
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Zhu BH et al. (-)-Epigallocatechin-3-gallate inhibits growth of gastric cancer by reducing VEGF production and angiogenesis. 2007 World J. Gastroenterol. pmid:17451194
He W et al. Epigallocatechin gallate inhibits HBV DNA synthesis in a viral replication - inducible cell line. 2011 World J. Gastroenterol. pmid:21472112
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Wang X et al. Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice. 2017 World J. Gastroenterol. pmid:29290650
Ran ZH et al. Apoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45 via activation of the mitochondrial pathway. 2007 World J. Gastroenterol. pmid:17696257
Hoensch H et al. Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence. 2008 World J. Gastroenterol. pmid:18407592
Masamune A et al. Green tea polyphenol epigallocatechin-3-gallate blocks PDGF-induced proliferation and migration of rat pancreatic stellate cells. 2005 World J. Gastroenterol. pmid:15948241
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Lin YH et al. Dressing with epigallocatechin gallate nanoparticles for wound regeneration. 2016 Wound Repair Regen pmid:26472668
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Zhu BT et al. Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate. 2008 Xenobiotica pmid:18197555
Mohamed MF et al. Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity. 2010 Xenobiotica pmid:20666626
Yang W et al. Epigallocatechin-3-gallate decreases the transport and metabolism of simvastatin in rats. 2017 Xenobiotica pmid:27052517
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Wu LQ and Lu M [Efficacy of epigallocatechin gallate in treatment of alkali burn injury of murine cornea]. 2015 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:25851970
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Sun Q et al. [Biomodifying effect of epigallocatechin-3-gallate on dentine substrate splicing surface]. 2016 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:26980652
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Liu J et al. [Effect of epigallocatechin-3-gallate on the proliferation and osteogenesis of human periodontal ligament cells]. 2016 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:27978918
Yu HH et al. [Effects of epigallocatechin-3-gallate modification on the bonding stability of an etch-and-rinse adhesive to intraradicular dentin]. 2017 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:28253588
Zhu BH et al. [Epigallocatechin-3-gallate inhibits growth and angiogenesis of gastric cancer and its molecular mechanism]. 2009 Zhonghua Wei Chang Wai Ke Za Zhi pmid:19145512
Tang H et al. [Role and mechanism research on reversal of 5-fluorouracil resistance by epigallocatechin gallate in gastric cancer drug-resistance cells lines SGC-7901/5-FU]. 2016 Zhonghua Wei Chang Wai Ke Za Zhi pmid:27781257
Zhu BH et al. [(-)-Epigallocatechin-3-gallate reduces vascular endothelial growth factor expression in gastric cancer cells via suppressing activity]. 2011 Zhonghua Wei Chang Wai Ke Za Zhi pmid:21866460
Zhang CX et al. [Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1]. 2011 Zhonghua Wei Chang Wai Ke Za Zhi pmid:21866461
Fan B et al. [Neuroprotective effect of epigallocatechin gallate on oxidative-stress-injured retinal cells]. 2008 Zhonghua Yi Xue Za Zhi pmid:19024545
Chen XL et al. [Epigallocatechin-3-gallate induces apoptosis in human hepatocellular carcinoma cells]. 2008 Zhonghua Yi Xue Za Zhi pmid:19080641
Yang XY et al. [The role of NF-E2-related factor 2 in the induction of uridine 5'-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells]. 2006 Zhonghua Yi Xue Za Zhi pmid:16620709
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Han ZX et al. [The antagonistic action of epigallocatechin-3-gallate on microcystin LR-induced oxidative damage on hepatocytes of mice and the expression of cytochrome P450 2E1]. 2010 Zhonghua Yu Fang Yi Xue Za Zhi pmid:20388359
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Tong JL et al. [Epigallocatechin gallate induces apoptosis in human hepatocellular carcinoma HepG2 cells via TGF/Smad signaling pathway]. 2009 Zhonghua Zhong Liu Za Zhi pmid:20021857