(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Xu X et al. The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans. 2011 Antimicrob. Agents Chemother. pmid:21149622
Sharma S et al. Mass spectrometry-based systems approach for identification of inhibitors of Plasmodium falciparum fatty acid synthase. 2007 Antimicrob. Agents Chemother. pmid:17485508
Blanco AR et al. Epigallocatechin gallate inhibits biofilm formation by ocular staphylococcal isolates. 2005 Antimicrob. Agents Chemother. pmid:16189116
Pettinari A et al. Effect of polyphenolic compounds on the proteolytic activities of constitutive and immuno-proteasomes. 2006 Jan-Feb Antioxid. Redox Signal. pmid:16487045
Schroeder EK et al. Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons. 2009 Antioxid. Redox Signal. pmid:18754708
Bors W et al. Chemical studies of proanthocyanidins and hydrolyzable tannins. 2001 Antioxid. Redox Signal. pmid:11813994
Katz DL et al. Cocoa and chocolate in human health and disease. 2011 Antioxid. Redox Signal. pmid:21470061
Spencer JP et al. Bioavailability of flavan-3-ols and procyanidins: gastrointestinal tract influences and their relevance to bioactive forms in vivo. 2001 Antioxid. Redox Signal. pmid:11813978
Yum HW et al. Oligonol inhibits dextran sulfate sodium-induced colitis and colonic adenoma formation in mice. 2013 Antioxid. Redox Signal. pmid:23394584
Leonarduzzi G et al. Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol. 2006 Mar-Apr Antioxid. Redox Signal. pmid:16677084
Fink RC et al. HIV type-1 entry inhibitors with a new mode of action. 2009 Antivir. Chem. Chemother. pmid:19641233
Li S et al. Procyanidin B1 purified from Cinnamomi cortex suppresses hepatitis C virus replication. 2010 Antivir. Chem. Chemother. pmid:20710064
Li S et al. Epigallocatechin gallate inhibits the HIV reverse transcription step. 2011 Antivir. Chem. Chemother. pmid:21730371
de Oliveira A et al. Antiviral activity of theaflavin digallate against herpes simplex virus type 1. 2015 Antiviral Res. pmid:25818500
Orozco-Topete R et al. Safety and efficacy of Virend for topical treatment of genital and anal herpes simplex lesions in patients with AIDS. 1997 Antiviral Res. pmid:9217246
Mahmood N et al. Inhibition of HIV infection by flavanoids. 1993 Antiviral Res. pmid:8279812
Yamaguchi K et al. Inhibitory effects of (-)-epigallocatechin gallate on the life cycle of human immunodeficiency virus type 1 (HIV-1). 2002 Antiviral Res. pmid:11684313
Reid SP et al. HSPA5 is an essential host factor for Ebola virus infection. 2014 Antiviral Res. pmid:25017472
Nakashima H et al. Inhibition of human immunodeficiency viral replication by tannins and related compounds. 1992 Antiviral Res. pmid:1416904
Zu M et al. In vitro anti-influenza virus and anti-inflammatory activities of theaflavin derivatives. 2012 Antiviral Res. pmid:22521753
Nakayama M et al. Inhibition of the infectivity of influenza virus by tea polyphenols. 1993 Antiviral Res. pmid:8215301
Song JM et al. Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives. 2007 Antiviral Res. pmid:17709148
Weber C et al. The green tea catechin, epigallocatechin gallate inhibits chikungunya virus infection. 2015 Antiviral Res. pmid:25446334
Kim M et al. Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate. 2013 Antiviral Res. pmid:23954192
Safrin S et al. Treatment of acyclovir-unresponsive cutaneous herpes simplex virus infection with topically applied SP-303. 1994 Antiviral Res. pmid:7710268
Ferrea G et al. In vitro activity of a Combretum micranthum extract against herpes simplex virus types 1 and 2. 1993 Antiviral Res. pmid:8215303
Khan H et al. Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries. 2016 Antiviral Res. pmid:26593977
Gilbert BE et al. SP-303 small-particle aerosol treatment of influenza A virus infection in mice and respiratory syncytial virus infection in cotton rats. 1993 Antiviral Res. pmid:8317921
Wyde PR et al. The antiviral activity of SP-303, a natural polyphenolic polymer, against respiratory syncytial and parainfluenza type 3 viruses in cotton rats. 1993 Antiviral Res. pmid:8384824
Weber JM et al. Inhibition of adenovirus infection and adenain by green tea catechins. 2003 Antiviral Res. pmid:12742577
Gescher K et al. Oligomeric proanthocyanidins from Rumex acetosa L. inhibit the attachment of herpes simplex virus type-1. 2011 Antiviral Res. pmid:21070811
Xu J et al. Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro. 2008 Antiviral Res. pmid:18313149
Huang HC et al. (-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes. 2014 Antiviral Res. pmid:25260897
Song JM et al. Antiviral effect of catechins in green tea on influenza virus. 2005 Antiviral Res. pmid:16137775
Jin JS et al. Gordonibacter faecihominis sp. nov., isolated from human faeces. 2014 Antonie Van Leeuwenhoek pmid:24948086
Li BY et al. Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol. 2011 Apoptosis pmid:21505870
Manna S et al. Epigallocatechin gallate induced apoptosis in Sarcoma180 cells in vivo: mediated by p53 pathway and inhibition in U1B, U4-U6 UsnRNAs expression. 2006 Apoptosis pmid:17041754
Yu Y et al. Green tea catechins: a fresh flavor to anticancer therapy. 2014 Apoptosis pmid:24081390
Liu S et al. EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways. 2017 Apoptosis pmid:28317089
Lee MH et al. Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB. 2011 Apoptosis pmid:20963498
Karthikeyan B et al. Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration. 2017 Apoptosis pmid:27778132
Zhang T et al. Epigallocatechin-3-gallate enhances ischemia/reperfusion-induced apoptosis in human umbilical vein endothelial cells via AKT and MAPK pathways. 2009 Apoptosis pmid:19669889
Ji D et al. Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms. 2011 Apoptosis pmid:21279443
Lahiry L et al. Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis. 2008 Apoptosis pmid:18454316
Kim CH et al. Epicatechin protects auditory cells against cisplatin-induced death. 2008 Apoptosis pmid:18670884
Mazumdar M et al. Targeting RET to induce medullary thyroid cancer cell apoptosis: an antagonistic interplay between PI3K/Akt and p38MAPK/caspase-8 pathways. 2013 Apoptosis pmid:23329180
Haque A et al. Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2. 2015 Apoptosis pmid:25860284
Carter BE and Drewnowski A Beverages containing soluble fiber, caffeine, and green tea catechins suppress hunger and lead to less energy consumption at the next meal. 2012 Appetite pmid:22922604
Scholey A et al. Acute neurocognitive effects of epigallocatechin gallate (EGCG). 2012 Appetite pmid:22127270
Pence BD et al. Dose-dependent decrease in mortality with no cognitive or muscle function improvements due to dietary EGCG supplementation in aged mice. 2017 Appl Physiol Nutr Metab pmid:28177724