(-)-Epicatechin

(-)-Epicatechin is a lipid of Polyketides (PK) class.

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Current reference collection contains 55698 references associated with (-)-Epicatechin in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Dantas AM et al. Bioaccessibility of phenolic compounds in native and exotic frozen pulps explored in Brazil using a digestion model coupled with a simulated intestinal barrier. 2019 Food Chem pmid:30372928
Soares S et al. Effect of malvidin-3-glucoside and epicatechin interaction on their ability to interact with salivary proline-rich proteins. 2019 Food Chem pmid:30409602
Chen W et al. Effect of pH-shifting treatment on structural and functional properties of whey protein isolate and its interaction with (-)-epigallocatechin-3-gallate. 2019 Food Chem pmid:30372932
Owczarek A et al. A validated H qNMR method for direct and simultaneous quantification of esculin, fraxin and (-)-epicatechin in Hippocastani cortex. 2019 Talanta pmid:30348388
Schröder L et al. Effects of green tea, matcha tea and their components epigallocatechin gallate and quercetin on MCF‑7 and MDA-MB-231 breast carcinoma cells. 2019 Oncol. Rep. pmid:30320348
Chen Y et al. Structure-activity relationship of procyanidins on advanced glycation end products formation and corresponding mechanisms. 2019 Food Chem pmid:30309598
Liu B and Yan W Lipophilization of EGCG and effects on antioxidant activities. 2019 Food Chem pmid:30309596
Wang S et al. Integration of (+)-catechin and β-sitosterol to achieve excellent radical-scavenging activity in emulsions. 2019 Food Chem pmid:30309587
Sonmezdag AS et al. Effect of hulling methods and roasting treatment on phenolic compounds and physicochemical properties of cultivars 'Ohadi' and 'Uzun' pistachios (Pistacia vera L.). 2019 Food Chem pmid:30309564
Wang Y et al. Novel insight into the role of withering process in characteristic flavor formation of teas using transcriptome analysis and metabolite profiling. 2019 Food Chem pmid:30309549
da Silva Sauthier MC et al. Screening of Mangifera indica L. functional content using PCA and neural networks (ANN). 2019 Food Chem pmid:30292356
Muñoz-Labrador A et al. Effects of high intensity ultrasound on disaggregation of a macromolecular procyanidin-rich fraction from Vitis vinifera L. seed extract and evaluation of its antioxidant activity. 2019 Ultrason Sonochem pmid:30219355
Kim TE et al. Effect of green tea catechins on the pharmacokinetics of digoxin in humans. 2018 Drug Des Devel Ther pmid:30022812
Imran A et al. Lipid peroxidation diminishing perspective of isolated theaflavins and thearubigins from black tea in arginine induced renal malfunctional rats. 2018 Lipids Health Dis pmid:30021615
Bustos AS et al. Interaction Between Phenolic Compounds and Lipase: The Influence of Solubility and Presence of Particles in the IC Value. 2018 J. Food Sci. pmid:30020550
André DM et al. Epigallocatechin-3-gallate protects against the exacerbation of allergic eosinophilic inflammation associated with obesity in mice. 2018 Int. Immunopharmacol. pmid:30015241
Shin S et al. (-)-Epigallocatechin gallate derivatives reduce the expression of both urokinase plasminogen activator and plasminogen activator inhibitor-1 to inhibit migration, adhesion, and invasion of MDA-MB-231 cells. 2018 Phytother Res pmid:30009577
Zhao L et al. Study on interaction between human salivary α-amylase and sorghum procyanidin tetramer: Binding characteristics and structural analysis. 2018 Int. J. Biol. Macromol. pmid:30001600
Alejo-Armijo A et al. Synthesis and Evaluation of Antimicrobial and Antibiofilm Properties of A-Type Procyanidin Analogues against Resistant Bacteria in Food. 2018 J. Agric. Food Chem. pmid:29464945
Gao C et al. Development of a Thiolysis HPLC Method for the Analysis of Procyanidins in Cranberry Products. 2018 J. Agric. Food Chem. pmid:29430926
Hammerbacher A et al. Gallocatechin biosynthesis via a flavonoid 3',5'-hydroxylase is a defense response in Norway spruce against infection by the bark beetle-associated sap-staining fungus Endoconidiophora polonica. 2018 Phytochemistry pmid:29421514
Fu Z et al. Effect of (-)-epigallocatechin gallate (EGCG) extracted from green tea in reducing the formation of acrylamide during the bread baking process. 2018 Food Chem pmid:29037673
Ghitescu RE et al. Catechin loaded PLGA submicron-sized fibers reduce levels of reactive oxygen species induced by MWCNT in vitro. 2018 Eur J Pharm Biopharm pmid:29031922
Qin FY et al. Choushenosides A-C, three dimeric catechin glucosides from Codonopsis pilosula collected in Yunnan province, China. 2018 Phytochemistry pmid:29864628
Pollicino T et al. Flavocoxid exerts a potent antiviral effect against hepatitis B virus. 2018 Inflamm. Res. pmid:29018874
Wang Q et al. Green tea polyphenol epigallocatechin-3-gallate increases atherosclerotic plaque stability in apolipoprotein E-deficient mice fed a high-fat diet. 2018 Kardiol Pol pmid:29862488
Jain P et al. Antimicrobial metabolites from Saraca asoca impairs the membrane transport system and quorum-sensing system in Pseudomonas aeruginosa. 2018 Arch. Microbiol. pmid:28993916
Pang X et al. Identification of Estrogen Receptor Antagonists from Natural Products via and Approaches. 2018 Oxid Med Cell Longev pmid:29861831
Xiong LG et al. Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans. 2018 Redox Biol pmid:28992589
Tan C et al. Catechin modulates the copigmentation and encapsulation of anthocyanins in polyelectrolyte complexes (PECs) for natural colorant stabilization. 2018 Food Chem pmid:29853386
Kfoury N et al. Striking changes in tea metabolites due to elevational effects. 2018 Food Chem pmid:29853384
Ding S et al. Regulation of Immune Function by Polyphenols. 2018 J Immunol Res pmid:29850614
Di Gennaro P et al. Polyphenol Polymerization by an Alternative Oxidative Microbial Enzyme and Characterization of the Biological Activity of Oligomers. 2018 Biomed Res Int pmid:29850510
Micali A et al. Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity. 2018 Oxid Med Cell Longev pmid:29849925
Cao T et al. Antioxidant effects of epigallocatechin-3-gallate on the aTC1-6 pancreatic alpha cell line. 2018 Biochem. Biophys. Res. Commun. pmid:29117537
Ferreira-Nunes R et al. Versatile chromatographic method for catechin determination in development of topical formulations containing natural extracts. 2018 Biomed. Chromatogr. pmid:28809050
Satsu H et al. Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells. 2018 Biosci. Biotechnol. Biochem. pmid:29191128
Al-Sayed E and Abdel-Daim MM Analgesic and anti-inflammatory activities of epicatechin gallate from Bauhinia hookeri. 2018 Drug Dev. Res. pmid:29732583
Carbonaro M et al. Human insulin fibrillogenesis in the presence of epigallocatechin gallate and melatonin: Structural insights from a biophysical approach. 2018 Int. J. Biol. Macromol. pmid:29727655
Sano T et al. Effect of shading intensity on morphological and color traits and on chemical components of new tea (Camellia sinensis L.) shoots under direct covering cultivation. 2018 J. Sci. Food Agric. pmid:29722013
Cabrera R et al. Bioavailability of Compounds Susceptible to Enzymatic Oxidation Enhances Growth of Shiitake Medicinal Mushroom (Lentinus edodes) in Solid-State Fermentation with Vineyard Prunings. 2018 Int J Med Mushrooms pmid:29717673
Tang P et al. Honokiol nanoparticles based on epigallocatechin gallate functionalized chitin to enhance therapeutic effects against liver cancer. 2018 Int J Pharm pmid:29715531
Midttun HLE et al. Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells. 2018 Food Funct pmid:29714395
Wang YQ et al. Suppressive Effects of EGCG on Cervical Cancer. 2018 Molecules pmid:30213130
Wei S et al. Grape seed procyanidin extract inhibits adipogenesis and stimulates lipolysis of porcine adipocytes in vitro. 2018 J. Anim. Sci. pmid:29701782
Park JE et al. Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies. 2018 Molecules pmid:29690635
BorutinskaitÄ— V et al. Green tea polyphenol EGCG causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells. 2018 Leuk. Lymphoma pmid:28641467
Wu X et al. Reducing the allergenic capacity of β-lactoglobulin by covalent conjugation with dietary polyphenols. 2018 Food Chem pmid:29606470
Dhima IT et al. Modulation of cisplatin cytotoxic activity against leiomyosarcoma cells by epigallocatechin-3-gallate. 2018 Nat. Prod. Res. pmid:28641455
Luo L et al. An approach for degradation of grape seed and skin proanthocyanidin polymers into oligomers by sulphurous acid. 2018 Food Chem pmid:29606439
Pradhan P and Nguyen ML Herpes simplex virus virucidal activity of MST-312 and epigallocatechin gallate. 2018 Virus Res. pmid:29604359
He Q et al. A novel superchilling storage - ice glazing (SS-IG) approach using biopolymer-based composite hydrogel to delay microbiological spoilage and organic oxidation of preserved tilapia. 2018 J. Sci. Food Agric. pmid:29603240
Varela-Castillo O et al. Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach. 2018 Exp. Oncol. pmid:29600977
Chen Y et al. Occurrence of Functional Molecules in the Flowers of Tea (Camellia sinensis) Plants: Evidence for a Second Resource. 2018 Molecules pmid:29596355
Ni J et al. Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells. 2018 Molecules pmid:29596305
Imran A et al. Exploring the potential of black tea based flavonoids against hyperlipidemia related disorders. 2018 Lipids Health Dis pmid:29592809
Hori K et al. Antioxidant phenolic compounds from the rhizomes of Astilbe rivularis. 2018 Nat. Prod. Res. pmid:28361551
Kim Y and Chang KO Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses. 2018 Virus Res. pmid:29382552
Li Y and Wu S Epigallocatechin gallate suppresses hepatic cholesterol synthesis by targeting SREBP-2 through SIRT1/FOXO1 signaling pathway. 2018 Mol. Cell. Biochem. pmid:29446047
Mi Y et al. EGCG evokes Nrf2 nuclear translocation and dampens PTP1B expression to ameliorate metabolic misalignment under insulin resistance condition. 2018 Food Funct pmid:29423494
Yang K and Chan CB Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on its antioxidant activity. 2018 Acta Pharmacol. Sin. pmid:29417944
Dai T et al. Investigation the interaction between procyanidin dimer and α-amylase: Spectroscopic analyses and molecular docking simulation. 2018 Int. J. Biol. Macromol. pmid:29408006
Xu YQ et al. Quality development and main chemical components of Tieguanyin oolong teas processed from different parts of fresh shoots. 2018 Food Chem pmid:29407922
Subramaniam D et al. Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer. 2018 Curr. Med. Chem. pmid:28137215
Sarmiento V et al. Synthesis of novel (-)-epicatechin derivatives as potential endothelial GPER agonists: Evaluation of biological effects. 2018 Bioorg. Med. Chem. Lett. pmid:29395974
Filippi A et al. Epigallocatechin-3-O-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines. 2018 Int J Food Sci Nutr pmid:29157036
Wang X et al. Physical properties and antioxidant capacity of chitosan/epigallocatechin-3-gallate films reinforced with nano-bacterial cellulose. 2018 Carbohydr Polym pmid:29111045
Sun M et al. Metabolic Flux Enhancement and Transcriptomic Analysis Displayed the Changes of Catechins Following Long-Term Pruning in Tea Trees ( Camellia sinensis). 2018 J. Agric. Food Chem. pmid:30021435
Kellett ME et al. Modification of the cellular antioxidant activity (CAA) assay to study phenolic antioxidants in a Caco-2 cell line. 2018 Food Chem pmid:29120793
Fujiki H et al. Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells. 2018 Mol. Cells pmid:29429153
Chaudhury S et al. Probing the inhibitory potency of epigallocatechin gallate against human γB-crystallin aggregation: Spectroscopic, microscopic and simulation studies. 2018 Spectrochim Acta A Mol Biomol Spectrosc pmid:29172128
Siddiqui H et al. Inhibition of Adipogenesis by Thiourea Derivatives. 2018 Med Chem pmid:29165090
Xin Z et al. UPLC-Orbitrap-MS/MS combined with chemometrics establishes variations in chemical components in green tea from Yunnan and Hunan origins. 2018 Food Chem pmid:30381222
Ha TJ et al. Isolation and identification of α-glucosidase inhibitory constituents from the seeds of Vigna nakashimae: Enzyme kinetic study with active phytochemical. 2018 Food Chem pmid:30381216
Abdеlaziz RR et al. Flavocoxid attenuates airway inflammation in ovalbumin-induced mouse asthma model. 2018 Chem. Biol. Interact. pmid:29986831
Zerbib M et al. New flavanol O-glycosides in grape and wine. 2018 Food Chem pmid:30381210
Gonzalez-Alfonso JL et al. Efficient α-Glucosylation of Epigallocatechin Gallate Catalyzed by Cyclodextrin Glucanotransferase from Thermoanaerobacter Species. 2018 J. Agric. Food Chem. pmid:29939740
Li Y et al. Reduction of Nε-(carboxymethyl) lysine by (-)-epicatechin and (-)-epigallocatechin gallate: The involvement of a possible trapping mechanism by catechin quinones. 2018 Food Chem pmid:30381208
Rao S et al. Q-TOF LC/MS identification and UHPLC-Online ABTS antioxidant activity guided mapping of barley polyphenols. 2018 Food Chem pmid:30381193
Ruta LL et al. Epigallocatechin-3-O-gallate, the main green tea component, is toxic to Saccharomyces cerevisiae cells lacking the Fet3/Ftr1. 2018 Food Chem pmid:30381188
Moreno-Ulloa A et al. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. 2018 Food Funct pmid:29171848
Ferreira PG et al. Detection of the antiviral activity of epicatechin isolated from Salacia crassifolia (Celastraceae) against Mayaro virus based on protein C homology modelling and virtual screening. 2018 Arch. Virol. pmid:29478125
Chassagne F et al. A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. 2018 Fitoterapia pmid:29477305
Scholl C et al. Population nutrikinetics of green tea extract. 2018 PLoS ONE pmid:29466429
Czerwińska ME et al. The influence of procyanidins isolated from small-leaved lime flowers (Tilia cordata Mill.) on human neutrophils. 2018 Fitoterapia pmid:29447978
Raekiansyah M et al. Inhibitory effect of the green tea molecule EGCG against dengue virus infection. 2018 Arch. Virol. pmid:29429035
Cai ZY et al. Bioavailability of Tea Catechins and Its Improvement. 2018 Molecules pmid:30217074
Zhang G et al. The application of pomelo peel as a carrier for adsorption of epigallocatechin-3-gallate. 2018 J. Sci. Food Agric. pmid:29393516
Shirakami Y and Shimizu M Possible Mechanisms of Green Tea and Its Constituents against Cancer. 2018 Molecules pmid:30205425
Venkatakrishnan K et al. Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea in a double-blind clinical trial. 2018 Food Funct pmid:29384173
Deng M et al. Effect of Storage Conditions on Phenolic Profiles and Antioxidant Activity of Litchi Pericarp. 2018 Molecules pmid:30200581
Higashino Y et al. Regioselective Synthesis of Procyanidin B6, A 4-6-Condensed (+)-Catechin Dimer, by Intramolecular Condensation. 2018 Molecules pmid:29346322
Qin CY et al. Epigallocatechin gallate attenuates mitochondrial DNA-induced inflammatory damage in the development of ventilator-induced lung injury. 2018 Phytomedicine pmid:30195870
Lai YH et al. Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice. 2018 BMC Complement Altern Med pmid:30189898
Jan S et al. Effect of environmental variables on phytonutrients of Origanum vulgare L. in the sub-humid region of the northwestern Himalayas. 2018 Environ Monit Assess pmid:30187208
Li X et al. (-)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice. 2018 Food Funct pmid:30183039
Bhattacharya D et al. Antibacterial activity of polyphenolic fraction of Kombucha against Vibrio cholerae: targeting cell membrane. 2018 Lett. Appl. Microbiol. pmid:29193174
James KD et al. Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice. 2018 Food Chem. Toxicol. pmid:29175576
Ganeshpurkar A and Saluja AK Protective effect of catechin on humoral and cell mediated immunity in rat model. 2018 Int. Immunopharmacol. pmid:29172063
Chung JO et al. Quercetin and fisetin enhanced the small intestine cellular uptake and plasma levels of epi-catechins in in vitro and in vivo models. 2018 Food Funct pmid:29168878